Tag Archives: uk

#437765 Video Friday: Massive Robot Joins ...

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):

AWS Cloud Robotics Summit – August 18-19, 2020 – [Online Conference]
CLAWAR 2020 – August 24-26, 2020 – [Virtual Conference]
ICUAS 2020 – September 1-4, 2020 – Athens, Greece
ICRES 2020 – September 28-29, 2020 – Taipei, Taiwan
IROS 2020 – October 25-29, 2020 – Las Vegas, Nevada
ICSR 2020 – November 14-16, 2020 – Golden, Colorado
Let us know if you have suggestions for next week, and enjoy today’s videos.

Here are some professional circus artists messing around with an industrial robot for fun, like you do.

The acrobats are part of Östgötateatern, a Swedish theatre group, and the chair bit got turned into its own act, called “The Last Fish.” But apparently the Swedish Work Environment Authority didn’t like that an industrial robot—a large ABB robotic arm—was being used in an artistic performance, arguing that the same safety measures that apply in a factory setting would apply on stage. In other words, the robot had to operate inside a protective cage and humans could not physically interact with it.

When told that their robot had to be removed, the acrobats went to court. And won! At least that’s what we understand from this Swedish press release. The court in Linköping, in southern Sweden, ruled that the safety measures taken by the theater had been sufficient. The group had worked with a local robotics firm, Dyno Robotics, to program the manipulator and learn how to interact with it as safely as possible. The robot—which the acrobats say is the eighth member of their troupe—will now be allowed to return.

[ Östgötateatern ]

Houston Mechathronics’ Aquanaut continues to be awesome, even in the middle of a pandemic. It’s taken the big step (big swim?) out of NASA’s swimming pool and into open water.

[ HMI ]

Researchers from Carnegie Mellon University and Facebook AI Research have created a navigation system for robots powered by common sense. The technique uses machine learning to teach robots how to recognize objects and understand where they’re likely to be found in house. The result allows the machines to search more strategically.

[ CMU ]

Cassie manages 2.1 m/s, which is uncomfortably fast in a couple of different ways.

Next, untethered. After that, running!

[ Michigan Robotics ]

Engineers at Caltech have designed a new data-driven method to control the movement of multiple robots through cluttered, unmapped spaces, so they do not run into one another.

Multi-robot motion coordination is a fundamental robotics problem with wide-ranging applications that range from urban search and rescue to the control of fleets of self-driving cars to formation-flying in cluttered environments. Two key challenges make multi-robot coordination difficult: first, robots moving in new environments must make split-second decisions about their trajectories despite having incomplete data about their future path; second, the presence of larger numbers of robots in an environment makes their interactions increasingly complex (and more prone to collisions).

To overcome these challenges, Soon-Jo Chung, Bren Professor of Aerospace, and Yisong Yue, professor of computing and mathematical sciences, along with Caltech graduate student Benjamin Rivière (MS ’18), postdoctoral scholar Wolfgang Hönig, and graduate student Guanya Shi, developed a multi-robot motion-planning algorithm called “Global-to-Local Safe Autonomy Synthesis,” or GLAS, which imitates a complete-information planner with only local information, and “Neural-Swarm,” a swarm-tracking controller augmented to learn complex aerodynamic interactions in close-proximity flight.

[ Caltech ]

Fetch Robotics’ Freight robot is now hauling around pulsed xenon UV lamps to autonomously disinfect spaces with UV-A, UV-B, and UV-C, all at the same time.

[ SmartGuard UV ]

When you’re a vertically symmetrical quadruped robot, there is no upside-down.

[ Ghost Robotics ]

In the virtual world, the objects you pick up do not exist: you can see that cup or pen, but it does not feel like you’re touching them. That presented a challenge to EPFL professor Herbert Shea. Drawing on his extensive experience with silicone-based muscles and motors, Shea wanted to find a way to make virtual objects feel real. “With my team, we’ve created very small, thin and fast actuators,” explains Shea. “They are millimeter-sized capsules that use electrostatic energy to inflate and deflate.” The capsules have an outer insulating membrane made of silicone enclosing an inner pocket filled with oil. Each bubble is surrounded by four electrodes, that can close like a zipper. When a voltage is applied, the electrodes are pulled together, causing the center of the capsule to swell like a blister. It is an ingenious system because the capsules, known as HAXELs, can move not only up and down, but also side to side and around in a circle. “When they are placed under your fingers, it feels as though you are touching a range of different objects,” says Shea.

[ EPFL ]

Through the simple trick of reversing motors on impact, a quadrotor can land much more reliably on slopes.

[ Sherbrooke ]

Turtlebot delivers candy at Harvard.

I <3 Turtlebot SO MUCH

[ Harvard ]

Traditional drone controllers are a little bit counterintuitive, because there’s one stick that’s forwards and backwards and another stick that’s up and down but they’re both moving on the same axis. How does that make sense?! Here’s a remote that gives you actual z-axis control instead.

[ Fenics ]

Thanks Ashley!

Lio is a mobile robot platform with a multifunctional arm explicitly designed for human-robot interaction and personal care assistant tasks. The robot has already been deployed in several health care facilities, where it is functioning autonomously, assisting staff and patients on an everyday basis.

[ F&P Robotics ]

Video shows a ground vehicle autonomously exploring and mapping a multi-storage garage building and a connected patio on Carnegie Mellon University campus. The vehicle runs onboard state estimation and mapping leveraging range, vision, and inertial sensing, local planning for collision avoidance, and terrain analysis. All processing is real-time and no post-processing involved. The vehicle drives at 2m/s through the exploration run. This work is dedicated to DARPA Subterranean Challange.

[ CMU ]

Raytheon UK’s flagship STEM programme, the Quadcopter Challenge, gives 14-15 year olds the chance to participate in a hands-on, STEM-based engineering challenge to build a fully operational quadcopter. Each team is provided with an identical kit of parts, tools and instructions to build and customise their quadcopter, whilst Raytheon UK STEM Ambassadors provide mentoring, technical support and deliver bite-size learning modules to support the build.

[ Raytheon ]

A video on some of the research work that is being carried out at The Australian Centre for Field Robotics, University of Sydney.

[ University of Sydney ]

Jeannette Bohg, assistant professor of computer science at Stanford University, gave one of the Early Career Award Keynotes at RSS 2020.

[ RSS 2020 ]

Adam Savage remembers Grant Imahara.

[ Tested ] Continue reading

Posted in Human Robots

#437695 Video Friday: Even Robots Know That You ...

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

CLAWAR 2020 – August 24-26, 2020 – [Online Conference]
Other Than Human – September 3-10, 2020 – Stockholm, Sweden
ICRES 2020 – September 28-29, 2020 – Taipei, Taiwan
AUVSI EXPONENTIAL 2020 – October 5-8, 2020 – [Online Conference]
IROS 2020 – October 25-29, 2020 – Las Vegas, Nev., USA
CYBATHLON 2020 – November 13-14, 2020 – [Online Event]
ICSR 2020 – November 14-16, 2020 – Golden, Colo., USA
Let us know if you have suggestions for next week, and enjoy today's videos.

From the Robotics and Perception Group at UZH comes Flightmare, a simulation environment for drones that combines a slick rendering engine with a robust physics engine that can run as fast as your system can handle.

Flightmare is composed of two main components: a configurable rendering engine built on Unity and a flexible physics engine for dynamics simulation. Those two components are totally decoupled and can run independently from each other. Flightmare comes with several desirable features: (i) a large multi-modal sensor suite, including an interface to extract the 3D point-cloud of the scene; (ii) an API for reinforcement learning which can simulate hundreds of quadrotors in parallel; and (iii) an integration with a virtual-reality headset for interaction with the simulated environment. Flightmare can be used for various applications, including path-planning, reinforcement learning, visual-inertial odometry, deep learning, human-robot interaction, etc.

[ Flightmare ]

Quadruped robots yelling at people to maintain social distancing is really starting to become a thing, for better or worse.

We introduce a fully autonomous surveillance robot based on a quadruped platform that can promote social distancing in complex urban environments. Specifically, to achieve autonomy, we mount multiple cameras and a 3D LiDAR on the legged robot. The robot then uses an onboard real-time social distancing detection system to track nearby pedestrian groups. Next, the robot uses a crowd-aware navigation algorithm to move freely in highly dynamic scenarios. The robot finally uses a crowd aware routing algorithm to effectively promote social distancing by using human-friendly verbal cues to send suggestions to overcrowded pedestrians.

[ Project ]

Thanks Fan!

The Personal Robotics Group at Oregon State University is looking at UV germicidal irradiation for surface disinfection with a Fetch Manipulator Robot.

Fetch Robot disinfecting dance party woo!

[ Oregon State ]

How could you not take a mask from this robot?

[ Reachy ]

This work presents the design, development and autonomous navigation of the alpha-version of our Resilient Micro Flyer, a new type of collision-tolerant small aerial robot tailored to traversing and searching within highly confined environments including manhole-sized tubes. The robot is particularly lightweight and agile, while it implements a rigid collision-tolerant design which renders it resilient during forcible interaction with the environment. Furthermore, the design of the system is enhanced through passive flaps ensuring smoother and more compliant collision which was identified to be especially useful in very confined settings.

[ ARL ]

Pepper can make maps and autonomously navigate, which is interesting, but not as interesting as its posture when it's wandering around.

Dat backing into the charging dock tho.

[ Pepper ]

RatChair a strategy for displacing big objects by attaching relatively small vibration sources. After learning how several random bursts of vibration affect its pose, an optimization algorithm discovers the optimal sequence of vibration patterns required to (slowly but surely) move the object to a specified position.

This is from 2015, why isn't all of my furniture autonomous yet?!

[ KAIST ]

The new SeaDrone Pro is designed to be the underwater equivalent of a quadrotor. This video is a rendering, but we've been assured that it does actually exist.

[ SeaDrone ]

Thanks Eduardo!

Porous Loops is a lightweight composite facade panel that shows the potential of 3D printing of mineral foams for building scale applications.

[ ETH ]

Thanks Fan!

Here's an interesting idea for a robotic gripper- it's what appears to be a snap bracelet coupled to a pneumatic actuator that allows the snap bracelet to be reset.

[ Georgia Tech ]

Graze is developing a commercial robotic lawnmower. They're also doing a sort of crowdfunded investment thing, which probably explains the painfully overproduced nature of the following video:

A couple things about this: the hard part, which the video skips over almost entirely, is the mapping, localization, and understanding where to mow and where not to mow. The pitch deck seems to suggest that this is mostly done through computer vision, a thing that's perhaps easy to do under controlled ideal conditions, but difficult to apply to a world full lawns that are all different. The commercial aspect is interesting because golf courses are likely as standardized as you can get, but the emphasis here on how much money they can make without really addressing any of the technical stuff makes me raise an eyebrow or two.

[ Graze ]

The record & playback X-series arm demo allows the user to record the arm's movements while motors are torqued off. Then, the user may torque the motor's on and watch the movements they just made playback!

[ Interbotix ]

Shadow Robot has a new teleop system for its hand. I'm guessing that it's even trickier to use than it looks.

[ Shadow Robot ]

Quanser Interactive Labs is a collection of virtual hardware-based laboratory activities that supplement traditional or online courses. Same as working with physical systems in the lab, students work with virtual twins of Quanser's most popular plants, develop their mathematical models, implement and simulate the dynamic behavior of these systems, design controllers, and validate them on a high-fidelity 3D real-time virtual models. The virtual systems not only look like the real ones, they also behave, can be manipulated, measured, and controlled like real devices. And finally, when students go to the lab, they can deploy their virtually-validated designs on actual physical equipment.

[ Quanser ]

This video shows robot-assisted heart surgery. It's amazing to watch if you haven't seen this sort of thing before, but be aware that there is a lot of blood.

This video demonstrates a fascinating case of robotic left atrial myxoma excision, narrated by Joel Dunning, Middlesbrough, UK. The Robotic platform provides superior visualisation and enhanced dexterity, through keyhole incisions. Robotic surgery is an integral part of our Minimally Invasive Cardiothoracic Surgery Program.

[ Tristan D. Yan ]

Thanks Fan!

In this talk, we present our work on learning control policies directly in simulation that are deployed onto real drones without any fine tuning. The presentation covers autonomous drone racing, drone acrobatics, and uncertainty estimation in deep networks.

[ RPG ] Continue reading

Posted in Human Robots

#437562 Video Friday: Aquanaut Robot Takes to ...

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

IROS 2020 – October 25-25, 2020 – [Online]
ICSR 2020 – November 14-16, 2020 – Golden, Colo., USA
Bay Area Robotics Symposium – November 20, 2020 – [Online]
ACRA 2020 – December 8-10, 2020 – [Online]
Let us know if you have suggestions for next week, and enjoy today's videos.

To prepare the Perseverance rover for its date with Mars, NASA’s Mars 2020 mission team conducted a wide array of tests to help ensure a successful entry, descent and landing at the Red Planet. From parachute verification in the world’s largest wind tunnel, to hazard avoidance practice in Death Valley, California, to wheel drop testing at NASA’s Jet Propulsion Laboratory and much more, every system was put through its paces to get ready for the big day. The Perseverance rover is scheduled to land on Mars on February 18, 2021.

[ JPL ]

Awesome to see Aquanaut—the “underwater transformer” we wrote about last year—take to the ocean!

Also their new website has SHARKS on it.

[ HMI ]

Nature has inspired engineers at UNSW Sydney to develop a soft fabric robotic gripper which behaves like an elephant's trunk to grasp, pick up and release objects without breaking them.

[ UNSW ]

Collaborative robots offer increased interaction capabilities at relatively low cost but, in contrast to their industrial counterparts, they inevitably lack precision. We address this problem by relying on a dual-arm system with laser-based sensing to measure relative poses between objects of interest and compensate for pose errors coming from robot proprioception.

[ Paper ]

Developed by NAVER LABS, with Korea University of Technology & Education (Koreatech), the robot arm now features an added waist, extending the available workspace, as well as a sensor head that can perceive objects. It has also been equipped with a robot hand “BLT Gripper” that can change to various grasping methods.

[ NAVER Labs ]

In case you were still wondering why SoftBank acquired Aldebaran and Boston Dynamics:

[ RobotStart ]

DJI's new Mini 2 drone is here with a commercial so hip it makes my teeth scream.

[ DJI ]

Using simple materials, such as plastic struts and cardboard rolls, the first prototype of the RBO Hand 3 is already capable of grasping a large range of different objects thanks to its opposable thumb.

The RBO Hand 3 performs an edge grasp before handing-over the object to a person. The hand actively exploits constraints in the environment (the tabletop) for grasping the object. Thanks to its compliance, this interaction is safe and robust.

[ TU Berlin ]

Flyability's Elios 2 helped researchers inspect Reactor Five at the Chernobyl nuclear disaster site in order to determine whether any uranium was present. Prior to this mission, Reactor Five had not been investigated since the disaster in April of 1986.

[ Flyability ]

Thanks Zacc!

SOTO 2 is here! Together with our development partners from the industry, we have greatly enhanced the SOTO prototype over the last two years. With the new version of the robot, Industry 4.0 will become a great deal more real: SOTO brings materials to the assembly line, just-in-time and completely autonomously.

[ Magazino ]

A drone that can fly sustainably for long distances over land and water, and can land almost anywhere, will be able to serve a wide range of applications. There are already drones that fly using ‘green’ hydrogen, but they either fly very slowly or cannot land vertically. That’s why researchers at TU Delft, together with the Royal Netherlands Navy and the Netherlands Coastguard, developed a hydrogen-powered drone that is capable of vertical take-off and landing whilst also being able to fly horizontally efficiently for several hours, much like regular aircraft. The drone uses a combination of hydrogen and batteries as its power source.

[ MAVLab ]

The National Nuclear User Facility for Hot Robotics (NNUF-HR) is an EPSRC funded facility to support UK academia and industry to deliver ground-breaking, impactful research in robotics and artificial intelligence for application in extreme and challenging nuclear environments.

[ NNUF ]

At the Karolinska University Laboratory in Sweden, an innovation project based around an ABB collaborative robot has increased efficiency and created a better working environment for lab staff.

[ ABB ]

What I find interesting about DJI's enormous new agricultural drone is that it's got a spinning obstacle detecting sensor that's a radar, not a lidar.

Also worth noting is that it seems to detect the telephone pole, but not the support wire that you can see in the video feed, although the visualization does make it seem like it can spot the power lines above.

[ DJI ]

Josh Pieper has spend the last year building his own quadruped, and you can see what he's been up to in just 12 minutes.

[ mjbots ]

Thanks Josh!

Dr. Ryan Eustice, TRI Senior Vice President of Automated Driving, delivers a keynote speech — “The Road to Vehicle Automation, a Toyota Guardian Approach” — to SPIE's Future Sensing Technologies 2020. During the presentation, Eustice provides his perspective on the current state of automated driving, summarizes TRI's Guardian approach — which amplifies human drivers, rather than replacing them — and summarizes TRI's recent developments in core AD capabilities.

[ TRI ]

Two excellent talks this week from UPenn GRASP Lab, from Ruzena Bajcsy and Vijay Kumar.

A panel discussion on the future of robotics and societal challenges with Dr. Ruzena Bajcsy as a Roboticist and Founder of the GRASP Lab.

In this talk I will describe the role of the White House Office of Science and Technology Policy in supporting science and technology research and education, and the lessons I learned while serving in the office. I will also identify a few opportunities at the intersection of technology and policy and broad societal challenges.

[ UPenn ]

The IROS 2020 “Perception, Learning, and Control for Autonomous Agile Vehicles” workshop is all online—here's the intro, but you can click through for a playlist that includes videos of the entire program, and slides are available as well.

[ NYU ] Continue reading

Posted in Human Robots

#437407 Nvidia’s Arm Acquisition Brings the ...

Artificial intelligence and mobile computing have been two of the most disruptive technologies of this century. The unification of the two companies that made them possible could have wide-ranging consequences for the future of computing.

California-based Nvidia’s graphics processing units (GPUs) have powered the deep learning revolution ever since Google researchers discovered in 2011 that they could run neural networks far more efficiently than conventional CPUs. UK company Arm’s energy-efficient chip designs have dominated the mobile and embedded computing markets for even longer.

Now the two will join forces after the American company announced a $40 billion deal to buy Arm from its Japanese owner, Softbank. In a press release announcing the deal, Nvidia touted its potential to rapidly expand the reach of AI into all areas of our lives.

“In the years ahead, trillions of computers running AI will create a new internet-of-things that is thousands of times larger than today’s internet-of-people,” said Nvidia founder and CEO Jensen Huang. “Uniting NVIDIA’s AI computing capabilities with the vast ecosystem of Arm’s CPU, we can advance computing from the cloud, smartphones, PCs, self-driving cars and robotics, to edge IoT, and expand AI computing to every corner of the globe.”

There are good reasons to believe the hype. The two companies are absolutely dominant in their respective fields—Nvidia’s GPUs support more than 97 percent of AI computing infrastructure offered by big cloud service providers, and Arm’s chips power more than 90 percent of smartphones. And there’s little overlap in their competencies, which means the relationship could be a truly symbiotic one.

“I think the deal “fits like a glove” in that Arm plays in areas that Nvidia does not or isn’t that successful, while NVIDIA plays in many places Arm doesn’t or isn’t that successful,” analyst Patrick Moorhead wrote in Forbes.

One of the most obvious directions would be to expand Nvidia’s AI capabilities to the kind of low-power edge devices that Arm excels in. There’s growing demand for AI in devices like smartphones, wearables, cars, and drones, where transmitting data to the cloud for processing is undesirable either for reasons of privacy or speed.

But there might also be fruitful exchanges in the other direction. Huang told Moorhead a major focus would be bringing Arm’s expertise in energy efficiency to the data center. That’s a big concern for technology companies whose electricity bills and green credentials are taking a battering thanks to the huge amounts of energy required to run millions of computer chips around the clock.

The deal may not be plain sailing, though, most notably due to the two companies’ differing business models. While Nvidia sells ready-made processors, Arm simply creates chip designs and then licenses them to other companies who can then customize them to their particular hardware needs. It operates on an open-licence basis whereby any company with the necessary cash can access its designs.

As a result, its designs are found in products built by hundreds of companies that license its innovations, including Apple, Samsung, Huawei, Qualcomm, and even Nvidia. Some, including two of the company’s co-founders, have raised concerns that the purchase by Nvidia, which competes with many of these other companies, could harm the neutrality that has been central to its success.

It’s possible this could push more companies towards RISC-V, an open-source technology developed by researchers at the University of California at Berkeley that rivals Arm’s and is not owned by any one company. However, there are plenty of reasons why most companies still prefer arm over the less feature-rich open-source option, and it might take a considerable push to convince Arm’s customers to jump ship.

The deal will also have to navigate some thorny political issues. Unions, politicians, and business leaders in the UK have voiced concerns that it could lead to the loss of high-tech jobs, and government sources have suggested conditions could be placed on the deal.

Regulators in other countries could also put a spanner in the works. China is concerned that if Arm becomes US-owned, many of the Chinese companies that rely on its technology could become victims of export restrictions as the China-US trade war drags on. South Korea is also wary that the deal could create a new technology juggernaut that could dent Samsung’s growth in similar areas.

Nvidia has made commitments to keep Arm’s headquarters in the UK, which it says should lessen concerns around jobs and export restrictions. It’s also pledged to open a new world-class technology center in Cambridge and build a state-of-the-art AI supercomputer powered by Arm’s chips there. Whether the deal goes through still hangs in the balance, but of it does it could spur a whole new wave of AI innovation.

Image Credit: Nvidia Continue reading

Posted in Human Robots

#437293 These Scientists Just Completed a 3D ...

Human brain maps are a dime a dozen these days. Maps that detail neurons in a certain region. Maps that draw out functional connections between those cells. Maps that dive deeper into gene expression. Or even meta-maps that combine all of the above.

But have you ever wondered: how well do those maps represent my brain? After all, no two brains are alike. And if we’re ever going to reverse-engineer the brain as a computer simulation—as Europe’s Human Brain Project is trying to do—shouldn’t we ask whose brain they’re hoping to simulate?

Enter a new kind of map: the Julich-Brain, a probabilistic map of human brains that accounts for individual differences using a computational framework. Rather than generating a static PDF of a brain map, the Julich-Brain atlas is also dynamic, in that it continuously changes to incorporate more recent brain mapping results. So far, the map has data from over 24,000 thinly sliced sections from 23 postmortem brains covering most years of adulthood at the cellular level. But the atlas can also continuously adapt to progress in mapping technologies to aid brain modeling and simulation, and link to other atlases and alternatives.

In other words, rather than “just another” human brain map, the Julich-Brain atlas is its own neuromapping API—one that could unite previous brain-mapping efforts with more modern methods.

“It is exciting to see how far the combination of brain research and digital technologies has progressed,” said Dr. Katrin Amunts of the Institute of Neuroscience and Medicine at Research Centre Jülich in Germany, who spearheaded the study.

The Old Dogma
The Julich-Brain atlas embraces traditional brain-mapping while also yanking the field into the 21st century.

First, the new atlas includes the brain’s cytoarchitecture, or how brain cells are organized. As brain maps go, these kinds of maps are the oldest and most fundamental. Rather than exploring how neurons talk to each other functionally—which is all the rage these days with connectome maps—cytoarchitecture maps draw out the physical arrangement of neurons.

Like a census, these maps literally capture how neurons are distributed in the brain, what they look like, and how they layer within and between different brain regions.

Because neurons aren’t packed together the same way between different brain regions, this provides a way to parse the brain into areas that can be further studied. When we say the brain’s “memory center,” the hippocampus, or the emotion center, the “amygdala,” these distinctions are based on cytoarchitectural maps.

Some may call this type of mapping “boring.” But cytoarchitecture maps form the very basis of any sort of neuroscience understanding. Like hand-drawn maps from early explorers sailing to the western hemisphere, these maps provide the brain’s geographical patterns from which we try to decipher functional connections. If brain regions are cities, then cytoarchitecture maps attempt to show trading or other “functional” activities that occur in the interlinking highways.

You might’ve heard of the most common cytoarchitecture map used today: the Brodmann map from 1909 (yup, that old), which divided the brain into classical regions based on the cells’ morphology and location. The map, while impactful, wasn’t able to account for brain differences between people. More recent brain-mapping technologies have allowed us to dig deeper into neuronal differences and divide the brain into more regions—180 areas in the cortex alone, compared with 43 in the original Brodmann map.

The new study took inspiration from that age-old map and transformed it into a digital ecosystem.

A Living Atlas
Work began on the Julich-Brain atlas in the mid-1990s, with a little help from the crowd.

The preparation of human tissue and its microstructural mapping, analysis, and data processing is incredibly labor-intensive, the authors lamented, making it impossible to do for the whole brain at high resolution in just one lab. To build their “Google Earth” for the brain, the team hooked up with EBRAINS, a shared computing platform set up by the Human Brain Project to promote collaboration between neuroscience labs in the EU.

First, the team acquired MRI scans of 23 postmortem brains, sliced the brains into wafer-thin sections, and scanned and digitized them. They corrected distortions from the chopping using data from the MRI scans and then lined up neurons in consecutive sections—picture putting together a 3D puzzle—to reconstruct the whole brain. Overall, the team had to analyze 24,000 brain sections, which prompted them to build a computational management system for individual brain sections—a win, because they could now track individual donor brains too.

Their method was quite clever. They first mapped their results to a brain template from a single person, called the MNI-Colin27 template. Because the reference brain was extremely detailed, this allowed the team to better figure out the location of brain cells and regions in a particular anatomical space.

However, MNI-Colin27’s brain isn’t your or my brain—or any of the brains the team analyzed. To dilute any of Colin’s potential brain quirks, the team also mapped their dataset onto an “average brain,” dubbed the ICBM2009c (catchy, I know).

This step allowed the team to “standardize” their results with everything else from the Human Connectome Project and the UK Biobank, kind of like adding their Google Maps layer to the existing map. To highlight individual brain differences, the team overlaid their dataset on existing ones, and looked for differences in the cytoarchitecture.

The microscopic architecture of neurons change between two areas (dotted line), forming the basis of different identifiable brain regions. To account for individual differences, the team also calculated a probability map (right hemisphere). Image credit: Forschungszentrum Juelich / Katrin Amunts
Based on structure alone, the brains were both remarkably different and shockingly similar at the same time. For example, the cortexes—the outermost layer of the brain—were physically different across donor brains of different age and sex. The region especially divergent between people was Broca’s region, which is traditionally linked to speech production. In contrast, parts of the visual cortex were almost identical between the brains.

The Brain-Mapping Future
Rather than relying on the brain’s visible “landmarks,” which can still differ between people, the probabilistic map is far more precise, the authors said.

What’s more, the map could also pool yet unmapped regions in the cortex—about 30 percent or so—into “gap maps,” providing neuroscientists with a better idea of what still needs to be understood.

“New maps are continuously replacing gap maps with progress in mapping while the process is captured and documented … Consequently, the atlas is not static but rather represents a ‘living map,’” the authors said.

Thanks to its structurally-sound architecture down to individual cells, the atlas can contribute to brain modeling and simulation down the line—especially for personalized brain models for neurological disorders such as seizures. Researchers can also use the framework for other species, and they can even incorporate new data-crunching processors into the workflow, such as mapping brain regions using artificial intelligence.

Fundamentally, the goal is to build shared resources to better understand the brain. “[These atlases] help us—and more and more researchers worldwide—to better understand the complex organization of the brain and to jointly uncover how things are connected,” the authors said.

Image credit: Richard Watts, PhD, University of Vermont and Fair Neuroimaging Lab, Oregon Health and Science University Continue reading

Posted in Human Robots