Tag Archives: tools
#438762 When Robots Enter the World, Who Is ...
Over the last half decade or so, the commercialization of autonomous robots that can operate outside of structured environments has dramatically increased. But this relatively new transition of robotic technologies from research projects to commercial products comes with its share of challenges, many of which relate to the rapidly increasing visibility that these robots have in society.
Whether it's because of their appearance of agency, or because of their history in popular culture, robots frequently inspire people’s imagination. Sometimes this is a good thing, like when it leads to innovative new use cases. And sometimes this is a bad thing, like when it leads to use cases that could be classified as irresponsible or unethical. Can the people selling robots do anything about the latter? And even if they can, should they?
Roboticists understand that robots, fundamentally, are tools. We build them, we program them, and even the autonomous ones are just following the instructions that we’ve coded into them. However, that same appearance of agency that makes robots so compelling means that it may not be clear to people without much experience with or exposure to real robots that a robot itself isn’t inherently good or bad—rather, as a tool, a robot is a reflection of its designers and users.
This can put robotics companies into a difficult position. When they sell a robot to someone, that person can, hypothetically, use the robot in any way they want. Of course, this is the case with every tool, but it’s the autonomous aspect that makes robots unique. I would argue that autonomy brings with it an implied association between a robot and its maker, or in this case, the company that develops and sells it. I’m not saying that this association is necessarily a reasonable one, but I think that it exists, even if that robot has been sold to someone else who has assumed full control over everything it does.
“All of our buyers, without exception, must agree that Spot will not be used to harm or intimidate people or animals, as a weapon or configured to hold a weapon”
—Robert Playter, Boston Dynamics
Robotics companies are certainly aware of this, because many of them are very careful about who they sell their robots to, and very explicit about what they want their robots to be doing. But once a robot is out in the wild, as it were, how far should that responsibility extend? And realistically, how far can it extend? Should robotics companies be held accountable for what their robots do in the world, or should we accept that once a robot is sold to someone else, responsibility is transferred as well? And what can be done if a robot is being used in an irresponsible or unethical way that could have a negative impact on the robotics community?
For perspective on this, we contacted folks from three different robotics companies, each of which has experience selling distinctive mobile robots to commercial end users. We asked them the same five questions about the responsibility that robotics companies have regarding the robots that they sell, and here’s what they had to say:
Do you have any restrictions on what people can do with your robots? If so, what are they, and if not, why not?
Péter Fankhauser, CEO, ANYbotics:
We closely work together with our customers to make sure that our solution provides the right approach for their problem. Thereby, the target use case is clear from the beginning and we do not work with customers interested in using our robot ANYmal outside the intended target applications. Specifically, we strictly exclude any military or weaponized uses and since the foundation of ANYbotics it is close to our heart to make human work easier, safer, and more enjoyable.
Robert Playter, CEO, Boston Dynamics:
Yes, we have restrictions on what people can do with our robots, which are outlined in our Terms and Conditions of Sale. All of our buyers, without exception, must agree that Spot will not be used to harm or intimidate people or animals, as a weapon or configured to hold a weapon. Spot, just like any product, must be used in compliance with the law.
Ryan Gariepy, CTO, Clearpath Robotics:
We do have strict restrictions and KYC processes which are based primarily on Canadian export control regulations. They depend on the type of equipment sold as well as where it is going. More generally, we also will not sell or support a robot if we know that it will create an uncontrolled safety hazard or if we have reason to believe that the buyer is unqualified to use the product. And, as always, we do not support using our products for the development of fully autonomous weapons systems.
More broadly, if you sell someone a robot, why should they be restricted in what they can do with it?
Péter Fankhauser, ANYbotics: We see the robot less as a simple object but more as an artificial workforce. This implies to us that the usage is closely coupled with the transfer of the robot and both the customer and the provider agree what the robot is expected to do. This approach is supported by what we hear from our customers with an increasing interest to pay for the robots as a service or per use.
Robert Playter, Boston Dynamics: We’re offering a product for sale. We’re going to do the best we can to stop bad actors from using our technology for harm, but we don’t have the control to regulate every use. That said, we believe that our business will be best served if our technology is used for peaceful purposes—to work alongside people as trusted assistants and remove them from harm’s way. We do not want to see our technology used to cause harm or promote violence. Our restrictions are similar to those of other manufacturers or technology companies that take steps to reduce or eliminate the violent or unlawful use of their products.
Ryan Gariepy, Clearpath Robotics: Assuming the organization doing the restricting is a private organization and the robot and its software is sold vs. leased or “managed,” there aren't strong legal reasons to restrict use. That being said, the manufacturer likewise has no obligation to continue supporting that specific robot or customer going forward. However, given that we are only at the very edge of how robots will reshape a great deal of society, it is in the best interest for the manufacturer and user to be honest with each other about their respective goals. Right now, you're not only investing in the initial purchase and relationship, you're investing in the promise of how you can help each other succeed in the future.
“If a robot is being used in a way that is irresponsible due to safety: intervene! If it’s unethical: speak up!”
—Péter Fankhauser, ANYbotics
What can you realistically do to make sure that people who buy your robots use them in the ways that you intend?
Péter Fankhauser, ANYbotics: We maintain a close collaboration with our customers to ensure their success with our solution. So for us, we have refrained from technical solutions to block unintended use.
Robert Playter, Boston Dynamics: We vet our customers to make sure that their desired applications are things that Spot can support, and are in alignment with our Terms and Conditions of Sale. We’ve turned away customers whose applications aren’t a good match with our technology. If customers misuse our technology, we’re clear in our Terms of Sale that their violations may void our warranty and prevent their robots from being updated, serviced, repaired, or replaced. We may also repossess robots that are not purchased, but leased. Finally, we will refuse future sales to customers that violate our Terms of Sale.
Ryan Gariepy, Clearpath Robotics: We typically work with our clients ahead of the purchase to make sure their expectations match reality, in particular on aspects like safety, supervisory requirements, and usability. It's far worse to sell a robot that'll sit on a shelf or worse, cause harm, then to not sell a robot at all, so we prefer to reduce the risk of this situation in advance of receiving an order or shipping a robot.
How do you evaluate the merit of edge cases, for example if someone wants to use your robot in research or art that may push the boundaries of what you personally think is responsible or ethical?
Péter Fankhauser, ANYbotics: It’s about the dialog, understanding, and figuring out alternatives that work for all involved parties and the earlier you can have this dialog the better.
Robert Playter, Boston Dynamics: There’s a clear line between exploring robots in research and art, and using the robot for violent or illegal purposes.
Ryan Gariepy, Clearpath Robotics: We have sold thousands of robots to hundreds of clients, and I do not recall the last situation that was not covered by a combination of export control and a general evaluation of the client's goals and expectations. I'm sure this will change as robots continue to drop in price and increase in flexibility and usability.
“You're not only investing in the initial purchase and relationship, you're investing in the promise of how you can help each other succeed in the future.”
—Ryan Gariepy, Clearpath Robotics
What should roboticists do if we see a robot being used in a way that we feel is unethical or irresponsible?
Péter Fankhauser, ANYbotics: If it’s irresponsible due to safety: intervene! If it’s unethical: speak up!
Robert Playter, Boston Dynamics: We want robots to be beneficial for humanity, which includes the notion of not causing harm. As an industry, we think robots will achieve long-term commercial viability only if people see robots as helpful, beneficial tools without worrying if they’re going to cause harm.
Ryan Gariepy, Clearpath Robotics: On a one off basis, they should speak to a combination of the user, the supplier or suppliers, the media, and, if safety is an immediate concern, regulatory or government agencies. If the situation in question risks becoming commonplace and is not being taken seriously, they should speak up more generally in appropriate forums—conferences, industry groups, standards bodies, and the like.
As more and more robots representing different capabilities become commercially available, these issues are likely to come up more frequently. The three companies we talked to certainly don’t represent every viewpoint, and we did reach out to other companies who declined to comment. But I would think (I would hope?) that everyone in the robotics community can agree that robots should be used in a way that makes people’s lives better. What “better” means in the context of art and research and even robots in the military may not always be easy to define, and inevitably there’ll be disagreement as to what is ethical and responsible, and what isn’t.
We’ll keep on talking about it, though, and do our best to help the robotics community to continue growing and evolving in a positive way. Let us know what you think in the comments. Continue reading
Posted in Human Robots
#437957 Meet Assembloids, Mini Human Brains With ...
It’s not often that a twitching, snowman-shaped blob of 3D human tissue makes someone’s day.
But when Dr. Sergiu Pasca at Stanford University witnessed the tiny movement, he knew his lab had achieved something special. You see, the blob was evolved from three lab-grown chunks of human tissue: a mini-brain, mini-spinal cord, and mini-muscle. Each individual component, churned to eerie humanoid perfection inside bubbling incubators, is already a work of scientific genius. But Pasca took the extra step, marinating the three components together inside a soup of nutrients.
The result was a bizarre, Lego-like human tissue that replicates the basic circuits behind how we decide to move. Without external prompting, when churned together like ice cream, the three ingredients physically linked up into a fully functional circuit. The 3D mini-brain, through the information highway formed by the artificial spinal cord, was able to make the lab-grown muscle twitch on demand.
In other words, if you think isolated mini-brains—known formally as brain organoids—floating in a jar is creepy, upgrade your nightmares. The next big thing in probing the brain is assembloids—free-floating brain circuits—that now combine brain tissue with an external output.
The end goal isn’t to freak people out. Rather, it’s to recapitulate our nervous system, from input to output, inside the controlled environment of a Petri dish. An autonomous, living brain-spinal cord-muscle entity is an invaluable model for figuring out how our own brains direct the intricate muscle movements that allow us stay upright, walk, or type on a keyboard.
It’s the nexus toward more dexterous brain-machine interfaces, and a model to understand when brain-muscle connections fail—as in devastating conditions like Lou Gehrig’s disease or Parkinson’s, where people slowly lose muscle control due to the gradual death of neurons that control muscle function. Assembloids are a sort of “mini-me,” a workaround for testing potential treatments on a simple “replica” of a person rather than directly on a human.
From Organoids to Assembloids
The miniature snippet of the human nervous system has been a long time in the making.
It all started in 2014, when Dr. Madeleine Lancaster, then a post-doc at Stanford, grew a shockingly intricate 3D replica of human brain tissue inside a whirling incubator. Revolutionarily different than standard cell cultures, which grind up brain tissue to reconstruct as a flat network of cells, Lancaster’s 3D brain organoids were incredibly sophisticated in their recapitulation of the human brain during development. Subsequent studies further solidified their similarity to the developing brain of a fetus—not just in terms of neuron types, but also their connections and structure.
With the finding that these mini-brains sparked with electrical activity, bioethicists increasingly raised red flags that the blobs of human brain tissue—no larger than the size of a pea at most—could harbor the potential to develop a sense of awareness if further matured and with external input and output.
Despite these concerns, brain organoids became an instant hit. Because they’re made of human tissue—often taken from actual human patients and converted into stem-cell-like states—organoids harbor the same genetic makeup as their donors. This makes it possible to study perplexing conditions such as autism, schizophrenia, or other brain disorders in a dish. What’s more, because they’re grown in the lab, it’s possible to genetically edit the mini-brains to test potential genetic culprits in the search for a cure.
Yet mini-brains had an Achilles’ heel: not all were made the same. Rather, depending on the region of the brain that was reverse engineered, the cells had to be persuaded by different cocktails of chemical soups and maintained in isolation. It was a stark contrast to our own developing brains, where regions are connected through highways of neural networks and work in tandem.
Pasca faced the problem head-on. Betting on the brain’s self-assembling capacity, his team hypothesized that it might be possible to grow different mini-brains, each reflecting a different brain region, and have them fuse together into a synchronized band of neuron circuits to process information. Last year, his idea paid off.
In one mind-blowing study, his team grew two separate portions of the brain into blobs, one representing the cortex, the other a deeper part of the brain known to control reward and movement, called the striatum. Shockingly, when put together, the two blobs of human brain tissue fused into a functional couple, automatically establishing neural highways that resulted in one of the most sophisticated recapitulations of a human brain. Pasca crowned this tissue engineering crème-de-la-crème “assembloids,” a portmanteau between “assemble” and “organoids.”
“We have demonstrated that regionalized brain spheroids can be put together to form fused structures called brain assembloids,” said Pasca at the time.” [They] can then be used to investigate developmental processes that were previously inaccessible.”
And if that’s possible for wiring up a lab-grown brain, why wouldn’t it work for larger neural circuits?
Assembloids, Assemble
The new study is the fruition of that idea.
The team started with human skin cells, scraped off of eight healthy people, and transformed them into a stem-cell-like state, called iPSCs. These cells have long been touted as the breakthrough for personalized medical treatment, before each reflects the genetic makeup of its original host.
Using two separate cocktails, the team then generated mini-brains and mini-spinal cords using these iPSCs. The two components were placed together “in close proximity” for three days inside a lab incubator, gently floating around each other in an intricate dance. To the team’s surprise, under the microscope using tracers that glow in the dark, they saw highways of branches extending from one organoid to the other like arms in a tight embrace. When stimulated with electricity, the links fired up, suggesting that the connections weren’t just for show—they’re capable of transmitting information.
“We made the parts,” said Pasca, “but they knew how to put themselves together.”
Then came the ménage à trois. Once the mini-brain and spinal cord formed their double-decker ice cream scoop, the team overlaid them onto a layer of muscle cells—cultured separately into a human-like muscular structure. The end result was a somewhat bizarre and silly-looking snowman, made of three oddly-shaped spherical balls.
Yet against all odds, the brain-spinal cord assembly reached out to the lab-grown muscle. Using a variety of tools, including measuring muscle contraction, the team found that this utterly Frankenstein-like snowman was able to make the muscle component contract—in a way similar to how our muscles twitch when needed.
“Skeletal muscle doesn’t usually contract on its own,” said Pasca. “Seeing that first twitch in a lab dish immediately after cortical stimulation is something that’s not soon forgotten.”
When tested for longevity, the contraption lasted for up to 10 weeks without any sort of breakdown. Far from a one-shot wonder, the isolated circuit worked even better the longer each component was connected.
Pasca isn’t the first to give mini-brains an output channel. Last year, the queen of brain organoids, Lancaster, chopped up mature mini-brains into slices, which were then linked to muscle tissue through a cultured spinal cord. Assembloids are a step up, showing that it’s possible to automatically sew multiple nerve-linked structures together, such as brain and muscle, sans slicing.
The question is what happens when these assembloids become more sophisticated, edging ever closer to the inherent wiring that powers our movements. Pasca’s study targets outputs, but what about inputs? Can we wire input channels, such as retinal cells, to mini-brains that have a rudimentary visual cortex to process those examples? Learning, after all, depends on examples of our world, which are processed inside computational circuits and delivered as outputs—potentially, muscle contractions.
To be clear, few would argue that today’s mini-brains are capable of any sort of consciousness or awareness. But as mini-brains get increasingly more sophisticated, at what point can we consider them a sort of AI, capable of computation or even something that mimics thought? We don’t yet have an answer—but the debates are on.
Image Credit: christitzeimaging.com / Shutterstock.com Continue reading
Posted in Human Robots