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Tag Archives: science & technology
#435793 Tiny Robots Carry Stem Cells Through a ...
Engineers have built microrobots to perform all sorts of tasks in the body, and can now add to that list another key skill: delivering stem cells. In a paper published today in Science Robotics, researchers describe propelling a magnetically-controlled, stem-cell-carrying bot through a live mouse.
Under a rotating magnetic field, the microrobots moved with rolling and corkscrew-style locomotion. The researchers, led by Hongsoo Choi and his team at the Daegu Gyeongbuk Institute of Science & Technology (DGIST), in South Korea, also demonstrated their bot’s moves in slices of mouse brain, in blood vessels isolated from rat brains, and in a multi-organ-on-a chip.
The invention provides an alternative way to deliver stem cells, which are increasingly important in medicine. Such cells can be coaxed into becoming nearly any kind of cell, making them great candidates for treating neurodegenerative disorders such as Alzheimer’s.
But delivering stem cells typically requires an injection with a needle, which lowers the survival rate of the stem cells, and limits their reach in the body. Microrobots, however, have the potential to deliver stem cells to precise, hard-to-reach areas, with less damage to surrounding tissue, and better survival rates, says Jin-young Kim, a principle investigator at DGIST-ETH Microrobotics Research Center, and an author on the paper.
The virtues of microrobots have inspired several research groups to propose and test different designs in simple conditions, such as microfluidic channels and other static environments. A group out of Hong Kong last year described a burr-shaped bot that carried cells through live, transparent zebrafish.
The new research presents a magnetically-actuated microrobot that successfully carried stem cells through a live mouse. In additional experiments, the cells, which had differentiated into brain cells such as astrocytes, oligodendrocytes, and neurons, transferred to microtissues on the multi-organ-on-a-chip. Taken together, the proof-of-concept experiments demonstrate the potential for microrobots to be used in human stem cell therapy, says Kim.
The team fabricated the robots with 3D laser lithography, and designed them in two shapes: spherical and helical. Using a rotating magnetic field, the scientists navigated the spherical-shaped bots with a rolling motion, and the helical bots with a corkscrew motion. These styles of locomotion proved more efficient than that from a simple pulling force, and were more suitable for use in biological fluids, the scientists reported.
The big challenge in navigating microbots in a live animal (or human body) is being able to see them in real time. Imaging with fMRI doesn’t work, because the magnetic fields interfere with the system. “To precisely control microbots in vivo, it is important to actually see them as they move,” the authors wrote in their paper.
That wasn’t possible during experiments in a live mouse, so the researchers had to check the location of the microrobots before and after the experiments using an optical tomography system called IVIS. They also had to resort to using a pulling force with a permanent magnet to navigate the microrobots inside the mouse, due to the limitations of the IVIS system.
Kim says he and his colleagues are developing imaging systems that will enable them to view in real time the locomotion of their microrobots in live animals. Continue reading
#435669 Watch World Champion Soccer Robots Take ...
RoboCup 2019 took place earlier this month down in Sydney, Australia. While there are many different events including RoboCup@Home, RoboCup Rescue, and a bunch of different soccer leagues, one of the most compelling events is middle-size league (MSL), where mobile robots each about the size of a fire hydrant play soccer using a regular size FIFA soccer ball. The robots are fully autonomous, making their own decisions in real time about when to dribble, pass, and shoot.
The long-term goal of RoboCup is this:
By the middle of the 21st century, a team of fully autonomous humanoid robot soccer players shall win a soccer game, complying with the official rules of FIFA, against the winner of the most recent World Cup.
While the robots are certainly not there yet, they're definitely getting closer.
Even if you’re not a particular fan of soccer, it’s impressive to watch the robots coordinate with each other, setting up multiple passes and changing tactics on the fly in response to the movements of the other team. And the ability of these robots to shoot accurately is world-class (like, human world-class), as they’re seemingly able to put the ball in whatever corner of the goal they choose with split-second timing.
The final match was between Tech United from Eindhoven University of Technology in the Netherlands (whose robots are called TURTLE), and Team Water from Beijing Information Science & Technology University. Without spoiling it, I can tell you that the game was tied within just the last few seconds, meaning that it had to go to overtime. You can watch the entire match on YouTube, or a 5-minute commentated highlight video here:
It’s become a bit of a tradition to have the winning MSL robots play a team of what looks to be inexperienced adult humans wearing long pants and dress shoes.
The fact that the robots managed to score even once is pretty awesome, and it also looks like the robots are playing very conservatively (more so than the humans) so as not to accidentally injure any of us fragile meatbags with our spindly little legs. I get that RoboCup wants its first team of robots that can beat a human World Cup winning team to be humanoids, but at the moment, the MSL robots are where all the skill is.
To get calibrated on the state of the art for humanoid soccer robots, here’s the adult size final, Team Nimbro from the University of Bonn in Germany versus Team Sweaty from Offenburg University in Germany:
Yup, still a lot of falling over.
There’s lots more RoboCup on YouTube: Some channels to find more matches include the official RoboCup 2019 channel, and Tech United Eindhoven’s channel, which has both live English commentary and some highlight videos.
[ RoboCup 2019 ] Continue reading
#435292 It’s a draw! Humanoid artist
There goes another human skill! This humanoid artist sketches people via AI. Any good? You decide…