Tag Archives: injury

#439077 How Scientists Grew Human Muscles in Pig ...

Posted on April 7, 2021 by Android

The little pigs bouncing around the lab looked exceedingly normal. Yet their adorable exterior hid a remarkable secret: each piglet carried two different sets of genes. For now, both sets came from their own species. But one day, one of those sets may be human.

The piglets are chimeras—creatures with intermingled sets of genes, as if multiple entities were seamlessly mashed together. Named after the Greek lion-goat-serpent monsters, chimeras may hold the key to an endless supply of human organs and tissues for transplant. The crux is growing these human parts in another animal—one close enough in size and function to our own.

Last week, a team from the University of Minnesota unveiled two mind-bending chimeras. One was joyous little piglets, each propelled by muscles grown from a different pig. Another was pig embryos, transplanted into surrogate pigs, that developed human muscles for more than 20 days.

The study, led by Drs. Mary and Daniel Garry at the University of Minnesota, had a therapeutic point: engineering a brilliant way to replace muscle loss, especially for the muscles around our skeletons that allow us to move and navigate the world. Trauma and injury, such as from firearm wounds or car crashes, can damage muscle tissue beyond the point of repair. Unfortunately, muscles are also stubborn in that donor tissue from cadavers doesn’t usually “take” at the injury site. For now, there are no effective treatments for severe muscle death, called volumetric muscle loss.

The new human-pig hybrids are designed to tackle this problem. Muscle wasting aside, the study also points to a clever “hack” that increases the amount of human tissue inside a growing pig embryo.

If further improved, the technology could “provide an unlimited supply of organs for transplantation,” said Dr. Mary Garry to Inverse. What’s more, because the human tissue can be sourced from patients themselves, the risk of rejection by the immune system is relatively low—even when grown inside a pig.

“The shortage of organs for heart transplantation, vascular grafting, and skeletal muscle is staggering,” said Garry. Human-animal chimeras could have a “seismic impact” that transforms organ transplantation and helps solve the organ shortage crisis.

That is, if society accepts the idea of a semi-humanoid pig.

Wait…But How?
The new study took a page from previous chimera recipes.

The main ingredients and steps go like this: first, you need an embryo that lacks the ability to develop a tissue or organ. This leaves an “empty slot” of sorts that you can fill with another set of genes—pig, human, or even monkey.

Second, you need to fine-tune the recipe so that the embryos “take” the new genes, incorporating them into their bodies as if they were their own. Third, the new genes activate to instruct the growing embryo to make the necessary tissue or organs without harming the overall animal. Finally, the foreign genes need to stay put, without cells migrating to another body part—say, the brain.

Not exactly straightforward, eh? The piglets are technological wonders that mix cutting-edge gene editing with cloning technologies.

The team went for two chimeras: one with two sets of pig genes, the other with a pig and human mix. Both started with a pig embryo that can’t make its own skeletal muscles (those are the muscles surrounding your bones). Using CRISPR, the gene-editing Swiss Army Knife, they snipped out three genes that are absolutely necessary for those muscles to develop. Like hitting a bullseye with three arrows simultaneously, it’s already a technological feat.

Here’s the really clever part: the muscles around your bones have a slightly different genetic makeup than the ones that line your blood vessels or the ones that pump your heart. While the resulting pig embryos had severe muscle deformities as they developed, their hearts beat as normal. This means the gene editing cut only impacted skeletal muscles.

Then came step two: replacing the missing genes. Using a microneedle, the team injected a fertilized and slightly developed pig egg—called a blastomere—into the embryo. If left on its natural course, a blastomere eventually develops into another embryo. This step “smashes” the two sets of genes together, with the newcomer filling the muscle void. The hybrid embryo was then placed into a surrogate, and roughly four months later, chimeric piglets were born.

Equipped with foreign DNA, the little guys nevertheless seemed totally normal, nosing around the lab and running everywhere without obvious clumsy stumbles. Under the microscope, their “xenomorph” muscles were indistinguishable from run-of-the-mill average muscle tissue—no signs of damage or inflammation, and as stretchy and tough as muscles usually are. What’s more, the foreign DNA seemed to have only developed into muscles, even though they were prevalent across the body. Extensive fishing experiments found no trace of the injected set of genes inside blood vessels or the brain.

A Better Human-Pig Hybrid
Confident in their recipe, the team next repeated the experiment with human cells, with a twist. Instead of using controversial human embryonic stem cells, which are obtained from aborted fetuses, they relied on induced pluripotent stem cells (iPSCs). These are skin cells that have been reverted back into a stem cell state.

Unlike previous attempts at making human chimeras, the team then scoured the genetic landscape of how pig and human embryos develop to find any genetic “brakes” that could derail the process. One gene, TP53, stood out, which was then promptly eliminated with CRISPR.

This approach provides a way for future studies to similarly increase the efficiency of interspecies chimeras, the team said.

The human-pig embryos were then carefully grown inside surrogate pigs for less than a month, and extensively analyzed. By day 20, the hybrids had already grown detectable human skeletal muscle. Similar to the pig-pig chimeras, the team didn’t detect any signs that the human genes had sprouted cells that would eventually become neurons or other non-muscle cells.

For now, human-animal chimeras are not allowed to grow to term, in part to stem the theoretical possibility of engineering humanoid hybrid animals (shudder). However, a sentient human-pig chimera is something that the team specifically addressed. Through multiple experiments, they found no trace of human genes in the embryos’ brain stem cells 20 and 27 days into development. Similarly, human donor genes were absent in cells that would become the hybrid embryos’ reproductive cells.

Despite bioethical quandaries and legal restrictions, human-animal chimeras have taken off, both as a source of insight into human brain development and a well of personalized organs and tissues for transplant. In 2019, Japan lifted its ban on developing human brain cells inside animal embryos, as well as the term limit—to global controversy. There’s also the question of animal welfare, given that hybrid clones will essentially become involuntary organ donors.

As the debates rage on, scientists are nevertheless pushing the limits of human-animal chimeras, while treading as carefully as possible.

“Our data…support the feasibility of the generation of these interspecies chimeras, which will serve as a model for translational research or, one day, as a source for xenotransplantation,” the team said.

Image Credit: Christopher Carson on Unsplash Continue reading →

Posted in Human Robots

#439055 Stretch Is Boston Dynamics’ Take on a ...

Posted on April 2, 2021 by Android

Today, Boston Dynamics is announcing Stretch, a mobile robot designed to autonomously move boxes around warehouses. At first glance, you might be wondering why the heck this is a Boston Dynamics robot at all, since the dynamic mobility that we associate with most of their platforms is notably absent. The combination of strength and speed in Stretch’s arm is something we haven’t seen before in a mobile robot, and it’s what makes this a unique and potentially exciting entry into the warehouse robotics space.

Useful mobile manipulation in any environment that’s not almost entirely structured is still a significant challenge in robotics, and it requires a very difficult combination of sensing, intelligence, and dynamic motion, all of which are classic Boston Dynamics. But also classic Boston Dynamics is building really cool platforms, and only later trying to figure out a way of making them commercially viable. So why Stretch, why boxes, why now, and (the real question) why not Handle? We talk with Boston Dynamics’ Vice President of Product Engineering Kevin Blankespoor to find out.

Stretch is very explicitly a box-handling mobile robot for relatively well structured warehouses. It’s in no way designed to be a generalist that many of Boston Dynamics’ other robots are. And to be fair, this is absolutely how to make a robot that’s practical and cost effective right out of the crate: Identify a task that is dull or dirty or dangerous for humans, design a robot to do that task safely and efficiently, and deploy it with the expectation that it’ll be really good at that task but not necessarily much else. This is a very different approach than a robot like Spot, where the platform came first and the practical applications came later—with Stretch, it’s all about that specific task in a specific environment.

There are already robotic solutions for truck unloading, palletizing, and depalletizing, but Stretch seems to be uniquely capable. For truck unloading, the highest performance systems that I’m aware of are monstrous things (here’s one example from Honeywell) that use a ton of custom hardware to just sort of ingest the cargo within a trailer all at once. In a highly structured and predictable warehouse, this sort of thing may pay off over the long term, but it’s going to be extremely expensive and not very versatile at all.

Palletizing and depalletizing robots are much more common in warehouses today. They’re almost always large industrial arms surrounded by a network of custom conveyor belts and whatnot, suffering from the same sorts of constraints as a truck unloader— very capable in some situations, but generally high cost and low flexibility.

Photo: Boston Dynamics

Stretch is probably not going to be able to compete with either of these types of dedicated systems when it comes to sheer speed, but it offers lots of other critical advantages: It’s fast and easy to deploy, easy to use, and adaptable to a variety of different tasks without costly infrastructure changes. It’s also very much not Handle, which was Boston Dynamics’ earlier (although not that much earlier) attempt at a box-handling robot for warehouses, and (let’s be honest here) a much more Boston Dynamics-y thing than Stretch seems to be. To learn more about why the answer is Stretch rather than Handle, and how Stretch will fit into the warehouse of the very near future, we spoke with Kevin Blankespoor, Boston Dynamics’ VP of Product Engineering and chief engineer for both Handle and Stretch.

IEEE Spectrum: Tell me about Stretch!

Kevin Blankespoor: Stretch is the first mobile robot that we’ve designed specifically for the warehouse. It’s all about moving boxes. Stretch is a flexible robot that can move throughout the warehouse and do different tasks. During a typical day in the life of Stretch in the future, it might spend the morning on the inbound side of the warehouse unloading boxes from trucks. It might spend the afternoon in the aisles of the warehouse building up pallets to go to retailers and e-commerce facilities, and it might spend the evening on the outbound side of the warehouse loading boxes into the trucks. So, it really goes to where the work is.

There are already other robots that include truck unloading robots, palletizing and depalletizing robots, and mobile bases with arms on them. What makes Boston Dynamics the right company to introduce a new robot in this space?

We definitely thought through this, because there are already autonomous mobile robots [AMRs] out there. Most of them, though, are more like pallet movers or tote movers—they don't have an arm, and most of them are really just about moving something from point A to point B without manipulation capability. We've seen some experiments where people put arms on AMRs, but nothing that's made it very far in the market. And so when we started looking at Stretch, we realized we really needed to make a custom robot, and that it was something we could do quickly.

“We got a lot of interest from people who wanted to put Atlas to work in the warehouse, but we knew that we could build a simpler robot to do some of those same tasks.”

Stretch is built with pieces from Spot and Atlas and that gave us a big head start. For example, if you look at Stretch’s vision system, it's 2D cameras, depth sensors, and software that allows it to do obstacle detection, box detection, and localization. Those are all the same sensors and software that we've been using for years on our legged robots. And if you look closely at Stretch’s wrist joints, they're actually the same as Spot’s hips. They use the same electric motors, the same gearboxes, the same sensors, and they even have the same closed-loop controller controlling the joints.

If you were to buy an existing industrial robot arm with this kind of performance, it would be about four times heavier than the arm we built, and it's really hard to make that into a mobile robot. A lot of this came from our leg technology because it’s so important for our leg designs to be lightweight for the robots to balance. We took that same strength to weight advantage that we have, and built it into this arm. We're able to rapidly piece together things from our other robots to get us out of the gate quickly, so even though this looks like a totally different robot, we think we have a good head start going into this market.

At what point did you decide to go with an arm on a statically stable base on Stretch, rather than something more, you know, dynamic-y?

Stretch looks really different than the robots that Boston Dynamics has done in the past. But you'd be surprised how much similarity there is between our legged robots and Stretch under the hood. Looking back, we actually got our start on moving boxes with Atlas, and at that point it was just research and development. We were really trying to do force control for box grasping. We were picking up heavy boxes and maintaining balance and working on those fundamentals. We released a video of that as our first next-gen Atlas video, and it was interesting. We got a lot of interest from people who wanted to put Atlas to work in the warehouse, but we knew that we could build a simpler robot to do some of those same tasks.

So at this point we actually came up with Handle. The intent of Handle was to do a couple things—one was, we thought we could build a simpler robot that had Atlas’ attributes. Handle has a small footprint so it can fit in tight spaces, but it can pick up heavy boxes. And in addition to that, we had always really wanted to combine wheels and legs. We’d been talking about doing that for a decade and so Handle was a chance for us to try it.

We built a couple versions of Handle, and the first one was really just a prototype to kind of explore the morphology. But the second one was more purpose-built for warehouse tasks, and we started building pallets with that one and it looked pretty good. And then we started doing truck unloading with Handle, which was the pivotal moment. Handle could do it, but it took too long. Every time Handle grasped a box, it would have to roll back and then get to a place where it could spin itself to face forward and place the box, and trucks are very tight for a robot this size, so there's not a lot of room to maneuver. We knew the whole time that there was a robot like Stretch that was another alternative, but that's really when it became clear that Stretch would have a lot of advantages, and we started working on it about a year ago.

Stretch is certainly impressive in a practical way, but I’ll admit to really hoping that something like Handle could have turned out to be a viable warehouse robot.

I love the Handle project as well, and I’m very passionate about that robot. And there was a stage before we built Stretch where we thought, “this would be pretty standard looking compared to Handle, is it going to capture enough of the Boston Dynamics secret sauce?” But when you actually dissect all the problems within Stretch that you have to tackle, there are a lot of cool robotics problems left in there—the vision system, the planning, the manipulation, the grasping of the boxes—it's a lot harder to solve than it looks, and we're excited that we're actually getting fairly far down that road now.

What happens to Handle now?

Stretch has really taken over our team as far as warehouse products go. Handle we still use occasionally as a research robot, but it’s not actively under development. Stretch is really Handle’s descendent. Handle’s not retired, exactly, but we’re just using it for things like the dance video.

There’s still potential to do cool stuff with Handle. I do think that combining wheels with legs is very cool, and largely unexplored compared to its potential. So I still think that you're gonna see versions of robots combining wheels and legs like Handle, and maybe a version of Handle in the future that does more of that. But because we're switching this thread from research into product, Stretch is really the main focus now.

How autonomous is Stretch?

Stretch is semi-autonomous, and that means it really needs to work with people to tap into its full potential. With truck unloading, for example, a person will drive Stretch into the back of the truck and then basically point Stretch in the right direction and say go. And from that point on, everything’s autonomous. Stretch has its vision system and its mobility and it can detect all the boxes, grasp all boxes, and move them onto a conveyor all autonomously. This is something that takes people hours to do manually, and Stretch can go all the way until it gets to the last box, and the truck is empty. There are some parts of the truck unloading task that do require people, like verifying that the truck is in the right place and opening the doors. But this takes a person just a few minutes, and then the robot can spend hours or as long as it takes to do its job autonomously.

There are also other tasks in the warehouse where the autonomy will increase in the future. After truck unloading, the second thing we’ll take on is order building, which will be more in the aisles of a warehouse. For that, Stretch will be navigating around the warehouse, finding the right pallet it needs to take a box from, and loading it onto a new pallet. This will be a different model with more autonomy; you’ll still have people involved to some degree, but the robot will have a higher percentage of the time where it can work independently.

What kinds of constraints is Stretch operating under? Do the boxes all have to be stacked neatly in the back of the truck, do they have to be the same size, the same color, etc?

“This will be a different model with more autonomy. You’ll still have people involved to some degree, but the robot will have a higher percentage of the time where it can work independently.”

If you think about manufacturing, where there's been automation for decades, you can go into a modern manufacturing facility and there are robot arms and conveyors and other machines. But if you look at the actual warehouse space, 90+ percent is manually operated, and that's because of what you just asked about— things that are less structured, where there’s more variety, and it's more challenging for a robot. But this is starting to change. This is really, really early days, and you’re going to be seeing a lot more robots in the warehouse space.

The warehouse robotics industry is going to grow a lot over the next decade, and a lot of that boils down to vision—the ability for robots to navigate and to understand what they’re seeing. Actually seeing boxes in real world scenarios is challenging, especially when there's a lot of variety. We've been testing our machine learning-based box detection system on Pick for a few years now, and it's gotten far enough that we know it’s one of the technical hurdles you need to overcome to succeed in the warehouse.

Can you compare the performance of Stretch to the performance of a human in a box-unloading task?

Stretch can move cases up to 50 pounds which is the OSHA limit for how much a single person's allowed to move. The peak case rate for Stretch is 800 cases per hour. You really need to keep up with the flow of goods throughout the warehouse, and 800 cases per hour should be enough for most applications. This is similar to a really good human; most humans are probably slower, and it’s hard for a human to sustain that rate, and one of the big issues with people doing this jobs is injury rates. Imagine moving really heavy boxes all day, and having to reach up high or bend down to get them—injuries are really common in this area. Truck unloading is one of the hardest jobs in a warehouse, and that’s one of the reasons we’re starting there with Stretch.

Is Stretch safe for humans to be around?

We looked at using collaborative robot arms for Stretch, but they don’t have the combination of strength and speed and reach to do this task. That’s partially just due to the laws of physics—if you want to move a 50lb box really fast, that’s a lot of energy there. So, Stretch does need to maintain separation from humans, but it’s pretty safe when it’s operating in the back of a truck.

In the middle of a warehouse, Stretch will have a couple different modes. When it's traveling around it'll be kind of like an AMR, and use a safety-rated lidar making sure that it slows down or stops as people get closer. If it's parked and the arm is moving, it'll do the same thing, monitoring anyone getting close and either slow down or stop.

How do you see Stretch interacting with other warehouse robots?

For building pallet orders, we can do that in a couple of different ways, and we’re experimenting with partners in the AMR space. So you might have an AMR that moves the pallet around and then rendezvous with Stretch, and Stretch does the manipulation part and moves boxes onto the pallet, and then the AMR scuttles off to the next rendezvous point where maybe a different Stretch meets it. We’re developing prototypes of that behavior now with a few partners. Another way to do it is Stretch can actually pull the pallet around itself and do both tasks. There are two fundamental things that happen in the warehouse: there's movement of goods, and there's manipulation of goods, and Stretch can do both.

You’re aware that Hello Robot has a mobile manipulator called Stretch, right?

Great minds think alike! We know Aaron [Edsinger] from the Google days; we all used to be in the same company, and he’s a great guy. We’re in very different applications and spaces, though— Aaron’s robot is going into research and maybe a little bit into the consumer space, while this robot is on a much bigger scale aimed at industrial applications, so I think there’s actually a lot of space between our robots, in terms of how they’ll be used.

Editor’s Note: We did check in with Aaron Edsinger at Hello Robot, and he sees things a little bit differently. “We're disappointed they chose our name for their robot,” Edsinger told us. “We're seriously concerned about it and considering our options.” We sincerely hope that Boston Dynamics and Hello Robot can come to an amicable solution on this.
What’s the timeline for commercial deployment of Stretch?

This is a prototype of the Stretch robot, and anytime we design a new robot, we always like to build a prototype as quickly as possible so we can figure out what works and what doesn't work. We did that with our bipeds and quadrupeds as well. So, we get an early look at what we need to iterate, because any time you build the first thing, it's not the right thing, and you always need to make changes to get to the final version. We've got about six of those Stretch prototypes operating now. In parallel, our hardware team is finishing up the design of the productized version of Stretch. That version of Stretch looks a lot like the prototype, but every component has been redesigned from the ground up to be manufacturable, to be reliable, and to be higher performance.

For the productized version of Stretch, we’ll build up the first units this summer, and then it’ll go on sale next year. So this is kind of a sneak peak into what the final product will be.

How much does it cost, and will you be selling Stretch, or offering it as a service?

We’re not quite ready to talk about cost yet, but it’ll be cost effective, and similar in cost to existing systems if you were to combine an industrial robot arm, custom gripper, and mobile base. We’re considering both selling and leasing as a service, but we’re not quite ready to narrow it down yet.

Photo: Boston Dynamics

As with all mobile manipulators, what Stretch can do long-term is constrained far more by software than by hardware. With a fast and powerful arm, a mobile base, a solid perception system, and 16 hours of battery life, you can imagine how different grippers could enable all kinds of different capabilities. But we’re getting ahead of ourselves, because it’s a long, long way from getting a prototype to work pretty well to getting robots into warehouses in a way that’s commercially viable long-term, even when the use case is as clear as it seems to be for Stretch.

Stretch also could signal a significant shift in focus for Boston Dynamics. While Blankespoor’s comments about Stretch leveraging Boston Dynamics’ expertise with robots like Spot and Atlas are well taken, Stretch is arguably the most traditional robot that the company has designed, and they’ve done so specifically to be able to sell robots into industry. This is what you do if you’re a robotics company who wants to make money by selling robots commercially, which (historically) has not been what Boston Dynamics is all about. Despite its bonkers valuation, Boston Dynamics ultimately needs to make money, and robots like Stretch are a good way to do it. With that in mind, I wouldn’t be surprised to see more robots like this from Boston Dynamics—robots that leverage the company’s unique technology, but that are designed to do commercially useful tasks in a somewhat less flashy way. And if this strategy keeps Boston Dynamics around (while funding some occasional creative craziness), then I’m all for it. Continue reading →

Posted in Human Robots

#437851 Boston Dynamics’ Spot Robot Dog ...

Posted on December 2, 2020 by Android

Boston Dynamics has been fielding questions about when its robots are going to go on sale and how much they’ll cost for at least a dozen years now. I can say this with confidence, because that’s how long I’ve been a robotics journalist, and I’ve been pestering them about it the entire time. But it’s only relatively recently that the company started to make a concerted push away from developing robots exclusively for the likes of DARPA into platforms with more commercial potential, starting with a compact legged robot called Spot, first introduced in 2016.

Since then, we’ve been following closely as Spot has gone from a research platform to a product, and today, Boston Dynamics is announcing the final step in that process: commercial availability. You can now order a Spot Explorer Kit from the Boston Dynamics online store for US $74,500 (plus tax), shipping included, with delivery in 6 to 8 weeks. FINALLY!

Over the past 10 months or so, Boston Dynamics has leased Spot robots to carefully selected companies, research groups, and even a few individuals as part of their early adopter program—that’s where all of the clips in the video below came from. While there are over 100 Spots out in the world right now, getting one of them has required convincing Boston Dynamics up front that you knew more or less exactly what you wanted to do and how you wanted to do it. If you’re a big construction company or the Jet Propulsion Laboratory or Adam Savage, that’s all well and good, but for other folks who think that a Spot could be useful for them somehow and want to give it a shot, this new availability provides a fewer-strings attached opportunity to do some experimentation with the robot.

There’s a lot of cool stuff going on in that video, but we were told that the one thing that really stood out to the folks at Boston Dynamics was a 2-second clip that you can see on the left-hand side of the screen from 0:19 to 0:21. In it, Spot is somehow managing to walk across a spider web of rebar without getting tripped up, at faster than human speed. This isn’t something that Spot was specifically programmed to do, and in fact the Spot User Guide specifically identifies “rebar mesh” as an unsafe operating environment. But the robot just handles it, and that’s a big part of what makes Spot so useful—its ability to deal with (almost) whatever you can throw at it.

Before you get too excited, Boston Dynamics is fairly explicit that the current license for the robot is intended for commercial use, and the company specifically doesn’t want people to be just using it at home for fun. We know this because we asked (of course we asked), and they told us “we specifically don’t want people to just be using it at home for fun.” Drat. You can still buy one as an individual, but you have to promise that you’ll follow the terms of use and user guidelines, and it sounds like using a robot in your house might be the second-fastest way to invalidate your warranty:

SPOT IS AN AMAZING ROBOT, BUT IS NOT CERTIFIED SAFE FOR IN-HOME USE OR INTENDED FOR USE NEAR CHILDREN OR OTHERS WHO MAY NOT APPRECIATE THE HAZARDS ASSOCIATED WITH ITS OPERATION.

Not being able to get Spot to play with your kids may be disappointing, but for those of you with the sort of kids who are also students, the good news is that Boston Dynamics has carved out a niche for academic institutions, which can buy Spot at a discounted price. And if you want to buy a whole pack of Spots, there’s a bulk discount for Enterprise users as well.

What do you get for $74,500? All this!

Spot robot
Spot battery (2x)
Spot charger
Tablet controller and charger
Robot case for storage and transportation
FREE SHIPPING!

Photo: Boston Dynamics

The basic package includes the robot, two batteries, charger, a tablet controller, and a storage case.

You can view detailed specs here.

So is $75k a lot of money for a robot like Spot, or not all that much? We don’t have many useful points of comparison, partially because it’s not clear to what extent other pre-commercial quadrupedal robots (like ANYmal or Aliengo) share capabilities and features with Spot. For more perspective on Spot’s price tag, we spoke to Michael Perry, vice president of business development at Boston Dynamics.

IEEE Spectrum: Why is Spot so affordable?

Michael Perry: The main goal of selling the robot at this stage is to try to get it into the hands of as many application developers as possible, so that we can learn from the community what the biggest driver of value is for Spot. As a platform, unlocking the value of an ecosystem is our core focus right now.

Spectrum: Why is Spot so expensive?

Perry: Expensive is relative, but compared to the initial prototypes of Spot, we’ve been able to drop down the cost pretty significantly. One key thing has been designing it for robustness—we’ve put hundreds and hundreds of hours on the robot to make sure that it’s able to be successful when it falls, or when it has an electrostatic discharge. We’ve made sure that it’s able to perceive a wide variety of environments that are difficult for traditional vision-based sensors to handle. A lot of that engineering is baked into the core product so that you don’t have to worry about the mobility or robotic side of the equation, you can just focus on application development.

Photos: Boston Dynamics

Accessories for Spot include [clockwise from top left]: Spot GXP with additional ports for payload integration; Spot CAM with panorama camera and advanced comms; Spot CAM+ with pan-tilt-zoom camera for inspections; Spot EAP with lidar to enhance autonomy on large sites; Spot EAP+ with Spot CAM camera plus lidar; and Spot CORE for additional processing power.

The $75k that you’ll pay for the Spot Explorer Kit, it’s important to note, is just the base price for the robot. As with other things that fall into this price range (like a luxury car), there are all kinds of fun ways to drive that cost up with accessories, although for Spot, some of those accessories will be necessary for many (if not most) applications. For example, a couple of expansion ports to make it easier to install your own payloads on Spot will run you $1,275. An additional battery is $4,620. And if you want to really get some work done, the Enhanced Autonomy Package (with 360 cameras, lights, better comms, and a Velodyne VLP-16) will set you back an additional $34,570. If you were hoping for an arm, you’ll have to wait until the end of the year.

Each Spot also includes a year’s worth of software updates and a warranty, although the standard warranty just covers “defects related to materials and workmanship” not “I drove my robot off a cliff” or “I tried to take my robot swimming.” For that sort of thing (user error) to be covered, you’ll need to upgrade to the $12,000 Spot CARE premium service plan to cover your robot for a year as long as you don’t subject it to willful abuse, which both of those examples I just gave probably qualify as.

While we’re on the subject of robot abuse, Boston Dynamics has very sensibly devoted a substantial amount of the Spot User Guide to help new users understand how they should not be using their robot, in order to “lessen the risk of serious injury, death, or robot and other property damage.” According to the guide, some things that could cause Spot to fall include holes, cliffs, slippery surfaces (like ice and wet grass), and cords. Spot’s sensors also get confused by “transparent, mirrored, or very bright obstacles,” and the guide specifically says Spot “may crash into glass doors and windows.” Also this: “Spot cannot predict trajectories of moving objects. Do not operate Spot around moving objects such as vehicles, children, or pets.”

We should emphasize that this is all totally reasonable, and while there are certainly a lot of things to be aware of, it’s frankly astonishing that these are the only things that Boston Dynamics explicitly warns users against. Obviously, not every potentially unsafe situation or thing is described above, but the point is that Boston Dynamics is willing to say to new users, “here’s your robot, go do stuff with it” without feeling the need to hold their hand the entire time.

There’s one more thing to be aware of before you decide to buy a Spot, which is the following:

“All orders will be subject to Boston Dynamics’ Terms and Conditions of Sale which require the beneficial use of its robots.”

Specifically, this appears to mean that you aren’t allowed to (or supposed to) use the robot in a way that could hurt living things, or “as a weapon, or to enable any weapon.” The conditions of sale also prohibit using the robot for “any illegal or ultra-hazardous purpose,” and there’s some stuff in there about it not being cool to use Spot for “nuclear, chemical, or biological weapons proliferation, or development of missile technology,” which seems weirdly specific.

“Once you make a technology more broadly available, the story of it starts slipping out of your hands. Our hope is that ahead of time we’re able to clearly articulate the beneficial uses of the robot in environments where we think the robot has a high potential to reduce the risk to people, rather than potentially causing harm.”
—Michael Perry, Boston Dynamics

I’m very glad that Boston Dynamics is being so upfront about requiring that Spot is used beneficially. However, it does put the company in a somewhat challenging position now that these robots are being sold. Boston Dynamics can (and will) perform some amount of due-diligence before shipping a Spot, but ultimately, once the robots are in someone else’s hands, there’s only so much that BD can do.

Spectrum: Why is beneficial use important to Boston Dynamics?

Perry: One of the key things that we’ve highlighted many times in our license and terms of use is that we don’t want to see the robot being used in any way that inflicts physical harm on people or animals. There are philosophical reasons for that—I think all of us don’t want to see our technology used in a way that would hurt people. But also from a business perspective, robots are really terrible at conveying intention. In order for the robot to be helpful long-term, it has to be trusted as a piece of technology. So rather than looking at a robot and wondering, “is this something that could potentially hurt me,” we want people to think “this is a robot that’s here to help me.” To the extent that people associate Boston Dynamics with cutting edge robots, we think that this is an important stance for the rollout of our first commercial product. If we find out that somebody’s violated our terms of use, their warranty is invalidated, we won’t repair their product, and we have a licensing timeout that would prevent them from accessing their robot after that timeout has expired. It’s a remediation path, but we do think that it’s important to at least provide that as something that helps enforce our position on use of our technology.

It’s very important to keep all of this in context: Spot is a tool. It’s got some autonomy and the appearance of agency, but it’s still just doing what people tell it to do, even if those things might be unsafe. If you read through the user guide, it’s clear how much of an effort Boston Dynamics is making to try to convey the importance of safety to Spot users—and ultimately, barring some unforeseen and catastrophic software or hardware issues, safety is about the users, rather than Boston Dynamics or Spot itself. I bring this up because as we start seeing more and more Spots doing things without Boston Dynamics watching over them quite so closely, accidents are likely inevitable. Spot might step on someone’s foot. It might knock someone over. If Spot was perfectly safe, it wouldn’t be useful, and we have to acknowledge that its impressive capabilities come with some risks, too.

Photo: Boston Dynamics

Each Spot includes a year’s worth of software updates and a warranty, although the standard warranty just covers “defects related to materials and workmanship” not “I drove my robot off a cliff.”

Now that Spot is on the market for real, we’re excited to see who steps up and orders one. Depending on who the potential customer is, Spot could either seem like an impossibly sophisticated piece of technology that they’d never be able to use, or a magical way of solving all of their problems overnight. In reality, it’s of course neither of those things. For the former (folks with an idea but without a lot of robotics knowledge or experience), Spot does a lot out of the box, but BD is happy to talk with people and facilitate connections with partners who might be able to integrate specific software and hardware to get Spot to do a unique task. And for the latter (who may also be folks with an idea but without a lot of robotics knowledge or experience), BD’s Perry offers a reminder Spot is not Rosie the Robot, and would be equally happy to talk about what the technology is actually capable of doing.

Looking forward a bit, we asked Perry whether Spot’s capabilities mean that customers are starting to think beyond using robots to simply replace humans, and are instead looking at them as a way of enabling a completely different way of getting things done.

Spectrum: Do customers interested in Spot tend to think of it as a way of replacing humans at a specific task, or as a system that can do things that humans aren’t able to do?

Perry: There are what I imagine as three levels of people understanding the robot applications. Right now, we’re at level one, where you take a person out of this dangerous, dull job, and put a robot in. That’s the entry point. The second level is, using the robot, can we increase the production of that task? For example, take site documentation on a construction site—right now, people do 360 image capture of a site maybe once a week, and they might do a laser scan of the site once per project. At the second level, the question is, what if you were able to get that data collection every day, or multiple times a day? What kinds of benefits would that add to your process? To continue the construction example, the third level would be, how could we completely redesign this space now that we know that this type of automation is available? To take one example, there are some things that we cannot physically build because it’s too unsafe for people to be a part of that process, but if you were to apply robotics to that process, then you could potentially open up a huge envelope of design that has been inaccessible to people.

To order a Spot of your very own, visit shop.bostondynamics.com.

A version of this post appears in the August 2020 print issue as “$74,500 Will Fetch You a Spot.” Continue reading →

Posted in Human Robots

#437820 In-Shoe Sensors and Mobile Robots Keep ...

Posted on December 1, 2020 by Android

In shoe sensor

Researchers at Stevens Institute of Technology are leveraging some of the newest mechanical and robotic technologies to help some of our oldest populations stay healthy, active, and independent.

Yi Guo, professor of electrical and computer engineering and director of the Robotics and Automation Laboratory, and Damiano Zanotto, assistant professor of mechanical engineering, and director of the Wearable Robotic Systems Laboratory, are collaborating with Ashley Lytle, assistant professor in Stevens’ College of Arts and Letters, and Ashwini K. Rao of Columbia University Medical Center, to combine an assistive mobile robot companion with wearable in-shoe sensors in a system designed to help elderly individuals maintain the balance and motion they need to thrive.

“Balance and motion can be significant issues for this population, and if elderly people fall and experience an injury, they are less likely to stay fit and exercise,” Guo said. “As a consequence, their level of fitness and performance decreases. Our mobile robot companion can help decrease the chances of falling and contribute to a healthy lifestyle by keeping their walking function at a good level.”

The mobile robots are designed to lead walking sessions and using the in-shoe sensors, monitor the user’s gait, indicate issues, and adjust the exercise speed and pace. The initiative is part of a four-year National Science Foundation research project.

“For the first time, we’re integrating our wearable sensing technology with an autonomous mobile robot,” said Zanotto, who worked with elderly people at Columbia University Medical Center for three years before coming to Stevens in 2016. “It’s exciting to be combining these different areas of expertise to leverage the strong points of wearable sensing technology, such as accurately capturing human movement, with the advantages of mobile robotics, such as much larger computational powers.”

The team is developing algorithms that fuse real-time data from smart, unobtrusive, in-shoe sensors and advanced on-board sensors to inform the robot’s navigation protocols and control the way the robot interacts with elderly individuals. It’s a promising way to assist seniors in safely doing walking exercises and maintaining their quality of life.

Bringing the benefits of the lab to life

Guo and Zanotto are working with Lytle, an expert in social and health psychology, to implement a social connectivity capability and make the bi-directional interaction between human and robot even more intuitive, engaging, and meaningful for seniors.

“Especially during COVID, it’s important for elderly people living on their own to connect socially with family and friends,” Zanotto said, “and the robot companion will also offer teleconferencing tools to provide that interaction in an intuitive and transparent way.”

“We want to use the robot for social connectedness, perhaps integrating it with a conversation agent such as Alexa,” Guo added. “The goal is to make it a companion robot that can sense, for example, that you are cooking, or you’re in the living room, and help with things you would do there.”

It’s a powerful example of how abstract concepts can have meaningful real-life benefits.

“As engineers, we tend to work in the lab, trying to optimize our algorithms and devices and technologies,” Zanotto noted, “but at the end of the day, what we do has limited value unless it has impact on real life. It’s fascinating to see how the devices and technologies we’re developing in the lab can be applied to make a difference for real people.”

Maintaining balance in a global pandemic

Although COVID-19 has delayed the planned testing at a senior center in New York City, it has not stopped the team’s progress.

“Although we can’t test on elderly populations yet, our students are still testing in the lab,” Guo said. “This summer and fall, for the first time, the students validated the system’s real-time ability to monitor and assess the dynamic margin of stability during walking—in other words, to evaluate whether the person following the robot is walking normally or has a risk of falling. They’re also designing parameters for the robot to give early warnings and feedback that help the human subjects correct posture and gait issues while walking.”

Those warnings would be literally underfoot, as the in-shoe sensors would pulse like a vibrating cell phone to deliver immediate directional information to the subject.

“We’re not the first to use this vibrotactile stimuli technology, but this application is new,” Zanotto said.

So far, the team has published papers in top robotics publication venues including IEEE Transactions on Neural Systems and Rehabilitation Engineering and the 2020 IEEE International Conference on Robotics and Automation (ICRA). It’s a big step toward realizing the synergies of bringing the technical expertise of engineers to bear on the clinical focus on biometrics—and the real lives of seniors everywhere. Continue reading →

Posted in Human Robots

#435628 Soft Exosuit Makes Walking and Running ...

Posted on September 13, 2019 by Android

Researchers at Harvard’s Wyss Institute have been testing a flexible, lightweight exosuit that can improve your metabolic efficiency by 4 to 10 percent while walking and running. This is very important because, according to a press release from Harvard, the suit can help you be faster and more efficient, whether you’re “walking at a leisurely pace,” or “running for your life.” Great!

Making humans better at running for their lives is something that we don’t put nearly enough research effort into, I think. The problem may not come up very often, but when it does, it’s super important (because, bears). So, sign me up for anything that we can do to make our desperate flights faster or more efficient—especially if it’s a lightweight, wearable exosuit that’s soft, flexible, and comfortable to wear.

This is the same sort of exosuit that was part of a DARPA program that we wrote about a few years ago, which was designed to make it easier for soldiers to carry heavy loads for long distances.

Photos: Wyss Institute at Harvard University

The system uses two waist-mounted electrical motors connected with cables to thigh straps that run down around your butt. The motors pull on the cables at the same time that your muscles actuate, helping them out and reducing the amount of work that your muscles put in without decreasing the amount of force they exert on your legs. The entire suit (batteries included) weighs 5 kilograms (11 pounds).

In order for the cables to actuate at the right time, the suit tracks your gait with two inertial measurement units (IMUs) on the thighs and one on the waist, and then adjusts its actuation profile accordingly. It works well, too, with measurable increases in performance:

We show that a portable exosuit that assists hip extension can reduce the metabolic rate of treadmill walking at 1.5 meters per second by 9.3 percent and that of running at 2.5 meters per second by 4.0 percent compared with locomotion without the exosuit. These reduction magnitudes are comparable to the effects of taking off 7.4 and 5.7 kilograms during walking and running, respectively, and are in a range that has shown meaningful athletic performance changes.

By increasing your efficiency, you can think of the suit as being able to make you walk or run faster, or farther, or carry a heavier load, all while spending the same amount of energy (or less), which could be just enough to outrun the bear that’s chasing you. Plus, it doesn’t appear to be uncomfortable to wear, and doesn’t require the user to do anything differently, which means that (unlike most robotics things) it’s maybe actually somewhat practical for real-world use—whether you’re indoors or outdoors, or walking or running, or being chased by a bear or not.

Sadly, I have no idea when you might be able to buy one of these things. But the researchers are looking for ways to make the suit even easier to use, while also reducing the weight and making the efficiency increase more pronounced. Harvard’s Conor Walsh says they’re “excited to continue to apply it to a range of applications, including assisting those with gait impairments, industry workers at risk of injury performing physically strenuous tasks, or recreational weekend warriors.” As a weekend warrior who is not entirely sure whether he can outrun a bear, I’m excited for this.

Reducing the metabolic rate of walking and running with a versatile, portable exosuit, by Jinsoo Kim, Giuk Lee, Roman Heimgartner, Dheepak Arumukhom Revi, Nikos Karavas, Danielle Nathanson, Ignacio Galiana, Asa Eckert-Erdheim, Patrick Murphy, David Perry, Nicolas Menard, Dabin Kim Choe, Philippe Malcolm, and Conor J. Walsh from the Wyss Institute for Biologically Inspired Engineering at Harvard University, appears in the current issue of Science. Continue reading →

Posted in Human Robots