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#432021 Unleashing Some of the Most Ambitious ...

At Singularity University, we are unleashing a generation of women who are smashing through barriers and starting some of the most ambitious technology companies on the planet.

Singularity University was founded in 2008 to empower leaders to use exponential technologies to solve our world’s biggest challenges. Our flagship program, the Global Solutions Program, has historically brought 80 entrepreneurs from around the world to Silicon Valley for 10 weeks to learn about exponential technologies and create moonshot startups that improve the lives of a billion people within a decade.

After nearly 10 years of running this program, we can say that about 70 percent of our successful startups have been founded or co-founded by female entrepreneurs (see below for inspiring examples of their work). This is in sharp contrast to the typical 10–20 percent of venture-backed tech companies that have a female founder, as reported by TechCrunch.

How are we so dramatically changing the game? While 100 percent of the credit goes to these courageous women, as both an alumna of the Global Solutions Program and our current vice chair of Global Grand Challenges, I want to share my reflections on what has worked.

At the most basic level, it is essential to deeply believe in the inherent worth, intellectual genius, and profound entrepreneurial caliber of women. While this may seem obvious, this is not the way our world currently thinks—we live in a world that sees women’s ideas, contributions, work, and existence as inherently less valuable than men’s.

For example, a 2017 Harvard Business Review article noted that even when women engage in the same behaviors and work as men, their work is considered less valuable simply because a woman did the job. An additional 2017 Harvard Business Review article showed that venture capitalists are significantly less likely to invest in female entrepreneurs and are more likely to ask men questions about the potential success of their companies while grilling women about the potential downfalls of their companies.

This doubt and lack of recognition of the genius and caliber of women is also why women are still paid less than men for completing identical work. Further, it’s why women’s work often gets buried in “number two” support roles of men in leadership roles and why women are expected to take on second shifts at home managing tedious household chores in addition to their careers. I would also argue these views as well as the rampant sexual harassment, assault, and violence against women that exists today stems from stubborn, historical, patriarchal views of women as living for the benefit of men, rather than for their own sovereignty and inherent value.

As with any other business, Singularity University has not been immune to these biases but is resolutely focused on helping women achieve intellectual genius and global entrepreneurial caliber by harnessing powerful exponential technologies.

We create an environment where women can physically and intellectually thrive free of harassment to reach their full potential, and we are building a broader ecosystem of alumni and partners around the world who not only support our female entrepreneurs throughout their entrepreneurial journeys, but who are also sparking and leading systemic change in their own countries and communities.

Respecting the Intellectual Genius and Entrepreneurial Caliber of Women
The entrepreneurial legends of our time—Steve Jobs, Elon Musk, Mark Zuckerberg, Bill Gates, Jeff Bezos, Larry Page, Sergey Brin—are men who have all built their empires using exponential technologies. Exponential technologies helped these men succeed faster and with greater impact due to Moore’s Law and the Law of Accelerating Returns which states that any digital technology (such as computing, software, artificial intelligence, robotics, quantum computing, biotechnology, nanotechnology, etc.) will become more sophisticated while dramatically falling in price, enabling rapid scaling.

Knowing this, an entrepreneur can plot her way to an ambitious global solution over time, releasing new applications just as the technology and market are ready. Furthermore, these rapidly advancing technologies often converge to create new tools and opportunities for innovators to come up with novel solutions to challenges that were previously impossible to solve in the past.

For various reasons, women have not pursued exponential technologies as aggressively as men (or were prevented or discouraged from doing so).

While more women are founding firms at a higher rate than ever in wealthy countries like the United States, the majority are small businesses in linear industries that have been around for hundreds of years, such as social assistance, health, education, administrative, or consulting services. In lower-income countries, international aid agencies and nonprofits often encourage women to pursue careers in traditional handicrafts, micro-enterprise, and micro-finance. While these jobs have historically helped women escape poverty and gain financial independence, they have done little to help women realize the enormous power, influence, wealth, and ability to transform the world for the better that comes from building companies, nonprofits, and solutions grounded in exponential technologies.

We need women to be working with exponential technologies today in order to be powerful leaders in the future.

Participants who enroll in our Global Solutions Program spend the first few weeks of the program learning about exponential technologies from the world’s experts and the final weeks launching new companies or nonprofits in their area of interest. We require that women (as well as men) utilize exponential technologies as a condition of the program.

In this sense, at Singularity University women start their endeavors with all of us believing and behaving in a way that assumes they can achieve global impact at the level of our world’s most legendary entrepreneurs.

Creating an Environment Where Woman Can Thrive
While challenging women to embrace exponential technologies is essential, it is also important to create an environment where women can thrive. In particular, this means ensuring women feel at home on our campus by ensuring gender diversity, aggressively addressing sexual harassment, and flipping the traditional culture from one that penalizes women, to one that values and supports them.

While women were initially only a small minority of our Global Solutions Program, in 2014, we achieved around 50% female attendance—a statistic that has since held over the years.

This is not due to a quota—every year we turn away extremely qualified women from our program (and are working on reformulating the program to allow more people to participate in the future.) While part of our recruiting success is due to the efforts of our marketing team, we also benefited from the efforts of some of our early female founders, staff, faculty, and alumnae including Susan Fonseca, Emeline Paat-Dahlstrom, Kathryn Myronuk, Lajuanda Asemota, Chiara Giovenzana, and Barbara Silva Tronseca.

As early champions of Singularity University these women not only launched diversity initiatives and personally reached out to women, but were crucial role models holding leadership roles in our community. In addition, Fonseca and Silva also both created multiple organizations and initiatives outside of (or in conjunction with) the university that produced additional pipelines of female candidates. In particular, Fonseca founded Women@TheFrontier as well as other organizations focusing on women, technology and innovation, and Silva founded BestInnovation (a woman’s accelerator in Latin America), as well as led Singularity University’s Chilean Chapter and founded the first SingularityU Summit in Latin America.

These women’s efforts in globally scaling Singularity University have been critical in ensuring woman around the world now see Singularity University as a place where they can lead and shape the future.

Also, thanks to Google (Alphabet) and many of our alumni and partners, we were able to provide full scholarships to any woman (or man) to attend our program regardless of their economic status. Google committed significant funding for full scholarships while our partners around the world also hosted numerous Global Impact Competitions, where entrepreneurs pitched their solutions to their local communities with the winners earning a full scholarship funded by our partners to attend the Global Solution Program as their prize.

Google and our partners’ support helped individuals attend our program and created a wider buzz around exponential technology and social change around the world in local communities. It led to the founding of 110 SU chapters in 55 countries.

Another vital aspect of our work in supporting women has been trying to create a harassment-free environment. Throughout the Silicon Valley, more than 60% of women convey that while they are trying to build their companies or get their work done, they are also dealing with physical and sexual harassment while being demeaned and excluded in other ways in the workplace. We have taken actions to educate and train our staff on how to deal with situations should they occur. All staff receives training on harassment when they join Singularity University, and all Global Solutions Program participants attend mandatory trainings on sexual harassment when they first arrive on campus. We also have male and female wellness counselors available that can offer support to both individuals and teams of entrepreneurs throughout the entire program.

While at a minimum our campus must be physically safe for women, we also strive to create a culture that values women and supports them in the additional challenges and expectations they face. For example, one of our 2016 female participants, Van Duesterberg, was pregnant during the program and said that instead of having people doubt her commitment to her startup or make her prove she could handle having a child and running a start-up at the same time, people went out of their way to help her.

“I was the epitome of a person not supposed to be doing a startup,” she said. “I was pregnant and would need to take care of my child. But Singularity University was supportive and encouraging. They made me feel super-included and that it was possible to do both. I continue to come back to campus even though the program is over because the network welcomes me and supports me rather than shuts me out because of my physical limitations. Rather than making me feel I had to prove myself, everyone just understood me and supported me, whether it was bringing me healthy food or recommending funders.”

Another strength that we have in supporting women is that after the Global Solutions Program, entrepreneurs have access to a much larger ecosystem.

Many entrepreneurs partake in SU Ventures, which can provide further support to startups as they develop, and we now have a larger community of over 200,000 people in almost every country. These members have often attended other Singularity University programs, events and are committed to our vision of the future. These women and men consist of business executives, Fortune 500 companies, investors, nonprofit and government leaders, technologists, members of the media, and other movers and shakers in the world. They have made introductions for our founders, collaborated with them on business ventures, invested in them and showcased their work at high profile events around the world.

Building for the Future
While our Global Solutions Program is making great strides in supporting female entrepreneurs, there is always more work to do. We are now focused on achieving the same degree of female participation across all of our programs and actively working to recruit and feature more female faculty and speakers on stage. As our community grows and scales around the world, we are also intent at how to best uphold our values and policies around sexual harassment across diverse locations and cultures. And like all businesses everywhere, we are focused on recruiting more women to serve at senior leadership levels within SU. As we make our way forward, we hope that you will join us in boldly leading this change and recognizing the genius and power of female entrepreneurs.

Meet Some of Our Female Moonshots
While we have many remarkable female entrepreneurs in the Singularity University community, the list below features a few of the women who have founded or co-founded companies at the Global Solutions Program that have launched new industries and are on their way to changing the way our world works for millions if not billions of people.

Jessica Scorpio co-founded Getaround in 2009. Getaround was one of the first car-sharing service platforms allowing anyone to rent out their car using a smartphone app. GetAround was a revolutionary idea in 2009, not only because smartphones and apps were still in their infancy, but because it was unthinkable that a technology startup could disrupt the major entrenched car, transport, and logistics companies. Scorpio’s early insights and pioneering entrepreneurial work brought to life new ways that humans relate to car sharing and the future self-driving car industry. Scorpio and Getaround have won numerous awards, and Getaround now serves over 200,000 members.

Paola Santana co-founded Matternet in 2011, which pioneered the commercial drone transport industry. In 2011, only military, hobbyists or the film industry used drones. Matternet demonstrated that drones could be used for commercial transport in short point-to-point deliveries for high-value goods laying the groundwork for drone transport around the world as well as some of the early thinking behind the future flying car industry. Santana was also instrumental in shaping regulations for the use of commercial drones around the world, making the industry possible.

Sara Naseri co-founded Qurasense in 2014, a life sciences start-up that analyzes women’s health through menstrual blood allowing women to track their health every month. Naseri is shifting our understanding of women’s menstrual blood as a waste product and something “not to be talked about,” to a rich, non-invasive, abundant source of information about women’s health.

Abi Ramanan co-founded ImpactVision in 2015, a software company that rapidly analyzes the quality and characteristics of food through hyperspectral images. Her long-term vision is to digitize food supply chains to reduce waste and fraud, given that one-third of all food is currently wasted before it reaches our plates. Ramanan is also helping the world understand that hyperspectral technology can be used in many industries to help us “see the unseen” and augment our ability to sense and understand what is happening around us in a much more sophisticated way.

Anita Schjøll Brede and Maria Ritola co-founded Iris AI in 2015, an artificial intelligence company that is building an AI research assistant that drastically improves the efficiency of R&D research and breaks down silos between different industries. Their long-term vision is for Iris AI to become smart enough that she will become a scientist herself. Fast Company named Iris AI one of the 10 most innovative artificial intelligence companies for 2017.

Hla Hla Win co-founded 360ed in 2016, a startup that conducts teacher training and student education through virtual reality and augmented reality in Myanmar. They have already connected teachers from 128 private schools in Myanmar with schools teaching 21st-century skills in Silicon Valley and around the world. Their moonshot is to build a platform where any teacher in the world can share best practices in teachers’ training. As they succeed, millions of children in some of the poorest parts of the world will have access to a 21st-century education.

Min FitzGerald and Van Duesterberg cofounded Nutrigene in 2017, a startup that ships freshly formulated, tailor-made supplement elixirs directly to consumers. Their long-term vision is to help people optimize their health using actionable data insights, so people can take a guided, tailored approaching to thriving into longevity.

Anna Skaya co-founded Basepaws in 2016, which created the first genetic test for cats and is building a community of citizen scientist pet owners. They are creating personalized pet products such as supplements, therapeutics, treats, and toys while also developing a database of genetic data for future research that will help both humans and pets over the long term.

Olivia Ramos co-founded Deep Blocks in 2016, a startup using artificial intelligence to integrate and streamline the processes of architecture, pre-construction, and real estate. As digital technologies, artificial intelligence, and robotics advance, it no longer makes sense for these industries to exist separately. Ramos recognized the tremendous value and efficiency that it is now possible to unlock with exponential technologies and creating an integrated industry in the future.

Please also visit our website to learn more about other female entrepreneurs, staff and faculty who are pioneering the future through exponential technologies. Continue reading

Posted in Human Robots

#431907 The Future of Cancer Treatment Is ...

In an interview at Singularity University’s Exponential Medicine in San Diego, Richard Wender, chief cancer control officer at the American Cancer Society, discussed how technology has changed cancer care and treatment in recent years.
Just a few years ago, microscopes were the primary tool used in cancer diagnoses, but we’ve come a long way since.
“We still look at a microscope, we still look at what organ the cancer started in,” Wender said. “But increasingly we’re looking at the molecular signature. It’s not just the genomics, and it’s not just the genes. It’s also the cellular environment around that cancer. We’re now targeting our therapies to the mutations that are found in that particular cancer.”
Cancer treatments in the past have been largely reactionary, but they don’t need to be. Most cancer is genetic, which means that treatment can be preventative. This is one reason why newer cancer treatment techniques are searching for actionable targets in the specific gene before the cancer develops.

When asked how artificial intelligence and machine learning technologies are reshaping clinical trials, Wender acknowledged that how clinical trials have been run in the past won’t work moving forward.
“Our traditional ways of learning about cancer were by finding a particular cancer type and conducting a long clinical trial that took a number of years enrolling patients from around the country. That is not how we’re going to learn to treat individual patients in the future.”
Instead, Wender emphasized the need for gathering as much data as possible, and from as many individual patients as possible. This data should encompass clinical, pathological, and molecular data and should be gathered from a patient all the way through their final outcome. “Literally every person becomes a clinical trial of one,” Wender said.
For the best cancer treatment and diagnostics, Wender says the answer is to make the process collaborative by pulling in resources from organizations and companies that are both established and emerging.
It’s no surprise to hear that the best solutions come from pairing together uncommon partners to innovate.
Image Credit: jovan vitanovski / Shutterstock.com Continue reading

Posted in Human Robots

#431872 AI Uses Titan Supercomputer to Create ...

You don’t have to dig too deeply into the archive of dystopian science fiction to uncover the horror that intelligent machines might unleash. The Matrix and The Terminator are probably the most well-known examples of self-replicating, intelligent machines attempting to enslave or destroy humanity in the process of building a brave new digital world.
The prospect of artificially intelligent machines creating other artificially intelligent machines took a big step forward in 2017. However, we’re far from the runaway technological singularity futurists are predicting by mid-century or earlier, let alone murderous cyborgs or AI avatar assassins.
The first big boost this year came from Google. The tech giant announced it was developing automated machine learning (AutoML), writing algorithms that can do some of the heavy lifting by identifying the right neural networks for a specific job. Now researchers at the Department of Energy’s Oak Ridge National Laboratory (ORNL), using the most powerful supercomputer in the US, have developed an AI system that can generate neural networks as good if not better than any developed by a human in less than a day.
It can take months for the brainiest, best-paid data scientists to develop deep learning software, which sends data through a complex web of mathematical algorithms. The system is modeled after the human brain and known as an artificial neural network. Even Google’s AutoML took weeks to design a superior image recognition system, one of the more standard operations for AI systems today.
Computing Power
Of course, Google Brain project engineers only had access to 800 graphic processing units (GPUs), a type of computer hardware that works especially well for deep learning. Nvidia, which pioneered the development of GPUs, is considered the gold standard in today’s AI hardware architecture. Titan, the supercomputer at ORNL, boasts more than 18,000 GPUs.
The ORNL research team’s algorithm, called MENNDL for Multinode Evolutionary Neural Networks for Deep Learning, isn’t designed to create AI systems that cull cute cat photos from the internet. Instead, MENNDL is a tool for testing and training thousands of potential neural networks to work on unique science problems.
That requires a different approach from the Google and Facebook AI platforms of the world, notes Steven Young, a postdoctoral research associate at ORNL who is on the team that designed MENNDL.
“We’ve discovered that those [neural networks] are very often not the optimal network for a lot of our problems, because our data, while it can be thought of as images, is different,” he explains to Singularity Hub. “These images, and the problems, have very different characteristics from object detection.”
AI for Science
One application of the technology involved a particle physics experiment at the Fermi National Accelerator Laboratory. Fermilab researchers are interested in understanding neutrinos, high-energy subatomic particles that rarely interact with normal matter but could be a key to understanding the early formation of the universe. One Fermilab experiment involves taking a sort of “snapshot” of neutrino interactions.
The team wanted the help of an AI system that could analyze and classify Fermilab’s detector data. MENNDL evaluated 500,000 neural networks in 24 hours. Its final solution proved superior to custom models developed by human scientists.
In another case involving a collaboration with St. Jude Children’s Research Hospital in Memphis, MENNDL improved the error rate of a human-designed algorithm for identifying mitochondria inside 3D electron microscopy images of brain tissue by 30 percent.
“We are able to do better than humans in a fraction of the time at designing networks for these sort of very different datasets that we’re interested in,” Young says.
What makes MENNDL particularly adept is its ability to define the best or most optimal hyperparameters—the key variables—to tackle a particular dataset.
“You don’t always need a big, huge deep network. Sometimes you just need a small network with the right hyperparameters,” Young says.
A Virtual Data Scientist
That’s not dissimilar to the approach of a company called H20.ai, a startup out of Silicon Valley that uses open source machine learning platforms to “democratize” AI. It applies machine learning to create business solutions for Fortune 500 companies, including some of the world’s biggest banks and healthcare companies.
“Our software is more [about] pattern detection, let’s say anti-money laundering or fraud detection or which customer is most likely to churn,” Dr. Arno Candel, chief technology officer at H2O.ai, tells Singularity Hub. “And that kind of insight-generating software is what we call AI here.”
The company’s latest product, Driverless AI, promises to deliver the data scientist equivalent of a chessmaster to its customers (the company claims several such grandmasters in its employ and advisory board). In other words, the system can analyze a raw dataset and, like MENNDL, automatically identify what features should be included in the computer model to make the most of the data based on the best “chess moves” of its grandmasters.
“So we’re using those algorithms, but we’re giving them the human insights from those data scientists, and we automate their thinking,” he explains. “So we created a virtual data scientist that is relentless at trying these ideas.”
Inside the Black Box
Not unlike how the human brain reaches a conclusion, it’s not always possible to understand how a machine, despite being designed by humans, reaches its own solutions. The lack of transparency is often referred to as the AI “black box.” Experts like Young say we can learn something about the evolutionary process of machine learning by generating millions of neural networks and seeing what works well and what doesn’t.
“You’re never going to be able to completely explain what happened, but maybe we can better explain it than we currently can today,” Young says.
Transparency is built into the “thought process” of each particular model generated by Driverless AI, according to Candel.
The computer even explains itself to the user in plain English at each decision point. There is also real-time feedback that allows users to prioritize features, or parameters, to see how the changes improve the accuracy of the model. For example, the system may include data from people in the same zip code as it creates a model to describe customer turnover.
“That’s one of the advantages of our automatic feature engineering: it’s basically mimicking human thinking,” Candel says. “It’s not just neural nets that magically come up with some kind of number, but we’re trying to make it statistically significant.”
Moving Forward
Much digital ink has been spilled over the dearth of skilled data scientists, so automating certain design aspects for developing artificial neural networks makes sense. Experts agree that automation alone won’t solve that particular problem. However, it will free computer scientists to tackle more difficult issues, such as parsing the inherent biases that exist within the data used by machine learning today.
“I think the world has an opportunity to focus more on the meaning of things and not on the laborious tasks of just fitting a model and finding the best features to make that model,” Candel notes. “By automating, we are pushing the burden back for the data scientists to actually do something more meaningful, which is think about the problem and see how you can address it differently to make an even bigger impact.”
The team at ORNL expects it can also make bigger impacts beginning next year when the lab’s next supercomputer, Summit, comes online. While Summit will boast only 4,600 nodes, it will sport the latest and greatest GPU technology from Nvidia and CPUs from IBM. That means it will deliver more than five times the computational performance of Titan, the world’s fifth-most powerful supercomputer today.
“We’ll be able to look at much larger problems on Summit than we were able to with Titan and hopefully get to a solution much faster,” Young says.
It’s all in a day’s work.
Image Credit: Gennady Danilkin / Shutterstock.com Continue reading

Posted in Human Robots

#431859 Digitized to Democratized: These Are the ...

“The Six Ds are a chain reaction of technological progression, a road map of rapid development that always leads to enormous upheaval and opportunity.”
–Peter Diamandis and Steven Kotler, Bold
We live in incredible times. News travels the globe in an instant. Music, movies, games, communication, and knowledge are ever-available on always-connected devices. From biotechnology to artificial intelligence, powerful technologies that were once only available to huge organizations and governments are becoming more accessible and affordable thanks to digitization.
The potential for entrepreneurs to disrupt industries and corporate behemoths to unexpectedly go extinct has never been greater.
One hundred or fifty or even twenty years ago, disruption meant coming up with a product or service people needed but didn’t have yet, then finding a way to produce it with higher quality and lower costs than your competitors. This entailed hiring hundreds or thousands of employees, having a large physical space to put them in, and waiting years or even decades for hard work to pay off and products to come to fruition.

“Technology is disrupting traditional industrial processes, and they’re never going back.”

But thanks to digital technologies developing at exponential rates of change, the landscape of 21st-century business has taken on a dramatically different look and feel.
The structure of organizations is changing. Instead of thousands of employees and large physical plants, modern start-ups are small organizations focused on information technologies. They dematerialize what was once physical and create new products and revenue streams in months, sometimes weeks.
It no longer takes a huge corporation to have a huge impact.
Technology is disrupting traditional industrial processes, and they’re never going back. This disruption is filled with opportunity for forward-thinking entrepreneurs.
The secret to positively impacting the lives of millions of people is understanding and internalizing the growth cycle of digital technologies. This growth cycle takes place in six key steps, which Peter Diamandis calls the Six Ds of Exponentials: digitization, deception, disruption, demonetization, dematerialization, and democratization.
According to Diamandis, cofounder and chairman of Singularity University and founder and executive chairman of XPRIZE, when something is digitized it begins to behave like an information technology.

Newly digitized products develop at an exponential pace instead of a linear one, fooling onlookers at first before going on to disrupt companies and whole industries. Before you know it, something that was once expensive and physical is an app that costs a buck.
Newspapers and CDs are two obvious recent examples. The entertainment and media industries are still dealing with the aftermath of digitization as they attempt to transform and update old practices tailored to a bygone era. But it won’t end with digital media. As more of the economy is digitized—from medicine to manufacturing—industries will hop on an exponential curve and be similarly disrupted.
Diamandis’s 6 Ds are critical to understanding and planning for this disruption.
The 6 Ds of Exponential Organizations are Digitized, Deceptive, Disruptive, Demonetized, Dematerialized, and Democratized.

Diamandis uses the contrasting fates of Kodak and Instagram to illustrate the power of the six Ds and exponential thinking.
Kodak invented the digital camera in 1975, but didn’t invest heavily in the new technology, instead sticking with what had always worked: traditional cameras and film. In 1996, Kodak had a $28 billion market capitalization with 95,000 employees.
But the company didn’t pay enough attention to how digitization of their core business was changing it; people were no longer taking pictures in the same way and for the same reasons as before.
After a downward spiral, Kodak went bankrupt in 2012. That same year, Facebook acquired Instagram, a digital photo sharing app, which at the time was a startup with 13 employees. The acquisition’s price tag? $1 billion. And Instagram had been founded only 18 months earlier.
The most ironic piece of this story is that Kodak invented the digital camera; they took the first step toward overhauling the photography industry and ushering it into the modern age, but they were unwilling to disrupt their existing business by taking a risk in what was then uncharted territory. So others did it instead.
The same can happen with any technology that’s just getting off the ground. It’s easy to stop pursuing it in the early part of the exponential curve, when development appears to be moving slowly. But failing to follow through only gives someone else the chance to do it instead.
The Six Ds are a road map showing what can happen when an exponential technology is born. Not every phase is easy, but the results give even small teams the power to change the world in a faster and more impactful way than traditional business ever could.
Image Credit: Mohammed Tareq / Shutterstock Continue reading

Posted in Human Robots

#431836 Do Our Brains Use Deep Learning to Make ...

The first time Dr. Blake Richards heard about deep learning, he was convinced that he wasn’t just looking at a technique that would revolutionize artificial intelligence. He also knew he was looking at something fundamental about the human brain.
That was the early 2000s, and Richards was taking a course with Dr. Geoff Hinton at the University of Toronto. Hinton, a pioneer architect of the algorithm that would later take the world by storm, was offering an introductory course on his learning method inspired by the human brain.
The key words here are “inspired by.” Despite Richards’ conviction, the odds were stacked against him. The human brain, as it happens, seems to lack a critical function that’s programmed into deep learning algorithms. On the surface, the algorithms were violating basic biological facts already proven by neuroscientists.
But what if, superficial differences aside, deep learning and the brain are actually compatible?
Now, in a new study published in eLife, Richards, working with DeepMind, proposed a new algorithm based on the biological structure of neurons in the neocortex. Also known as the cortex, this outermost region of the brain is home to higher cognitive functions such as reasoning, prediction, and flexible thought.
The team networked their artificial neurons together into a multi-layered network and challenged it with a classic computer vision task—identifying hand-written numbers.
The new algorithm performed well. But the kicker is that it analyzed the learning examples in a way that’s characteristic of deep learning algorithms, even though it was completely based on the brain’s fundamental biology.
“Deep learning is possible in a biological framework,” concludes the team.
Because the model is only a computer simulation at this point, Richards hopes to pass the baton to experimental neuroscientists, who could actively test whether the algorithm operates in an actual brain.
If so, the data could then be passed back to computer scientists to work out the next generation of massively parallel and low-energy algorithms to power our machines.
It’s a first step towards merging the two fields back into a “virtuous circle” of discovery and innovation.
The blame game
While you’ve probably heard of deep learning’s recent wins against humans in the game of Go, you might not know the nitty-gritty behind the algorithm’s operations.
In a nutshell, deep learning relies on an artificial neural network with virtual “neurons.” Like a towering skyscraper, the network is structured into hierarchies: lower-level neurons process aspects of an input—for example, a horizontal or vertical stroke that eventually forms the number four—whereas higher-level neurons extract more abstract aspects of the number four.
To teach the network, you give it examples of what you’re looking for. The signal propagates forward in the network (like climbing up a building), where each neuron works to fish out something fundamental about the number four.
Like children trying to learn a skill the first time, initially the network doesn’t do so well. It spits out what it thinks a universal number four should look like—think a Picasso-esque rendition.
But here’s where the learning occurs: the algorithm compares the output with the ideal output, and computes the difference between the two (dubbed “error”). This error is then “backpropagated” throughout the entire network, telling each neuron: hey, this is how far off you were, so try adjusting your computation closer to the ideal.
Millions of examples and tweakings later, the network inches closer to the desired output and becomes highly proficient at the trained task.
This error signal is crucial for learning. Without efficient “backprop,” the network doesn’t know which of its neurons are off kilter. By assigning blame, the AI can better itself.
The brain does this too. How? We have no clue.
Biological No-Go
What’s clear, though, is that the deep learning solution doesn’t work.
Backprop is a pretty needy function. It requires a very specific infrastructure for it to work as expected.
For one, each neuron in the network has to receive the error feedback. But in the brain, neurons are only connected to a few downstream partners (if that). For backprop to work in the brain, early-level neurons need to be able to receive information from billions of connections in their downstream circuits—a biological impossibility.
And while certain deep learning algorithms adapt a more local form of backprop— essentially between neurons—it requires their connection forwards and backwards to be symmetric. This hardly ever occurs in the brain’s synapses.
More recent algorithms adapt a slightly different strategy, in that they implement a separate feedback pathway that helps the neurons to figure out errors locally. While it’s more biologically plausible, the brain doesn’t have a separate computational network dedicated to the blame game.
What it does have are neurons with intricate structures, unlike the uniform “balls” that are currently applied in deep learning.
Branching Networks
The team took inspiration from pyramidal cells that populate the human cortex.
“Most of these neurons are shaped like trees, with ‘roots’ deep in the brain and ‘branches’ close to the surface,” says Richards. “What’s interesting is that these roots receive a different set of inputs than the branches that are way up at the top of the tree.”
This is an illustration of a multi-compartment neural network model for deep learning. Left: Reconstruction of pyramidal neurons from mouse primary visual cortex. Right: Illustration of simplified pyramidal neuron models. Image Credit: CIFAR
Curiously, the structure of neurons often turn out be “just right” for efficiently cracking a computational problem. Take the processing of sensations: the bottoms of pyramidal neurons are right smack where they need to be to receive sensory input, whereas the tops are conveniently placed to transmit feedback errors.
Could this intricate structure be evolution’s solution to channeling the error signal?
The team set up a multi-layered neural network based on previous algorithms. But rather than having uniform neurons, they gave those in middle layers—sandwiched between the input and output—compartments, just like real neurons.
When trained with hand-written digits, the algorithm performed much better than a single-layered network, despite lacking a way to perform classical backprop. The cell-like structure itself was sufficient to assign error: the error signals at one end of the neuron are naturally kept separate from input at the other end.
Then, at the right moment, the neuron brings both sources of information together to find the best solution.
There’s some biological evidence for this: neuroscientists have long known that the neuron’s input branches perform local computations, which can be integrated with signals that propagate backwards from the so-called output branch.
However, we don’t yet know if this is the brain’s way of dealing blame—a question that Richards urges neuroscientists to test out.
What’s more, the network parsed the problem in a way eerily similar to traditional deep learning algorithms: it took advantage of its multi-layered structure to extract progressively more abstract “ideas” about each number.
“[This is] the hallmark of deep learning,” the authors explain.
The Deep Learning Brain
Without doubt, there will be more twists and turns to the story as computer scientists incorporate more biological details into AI algorithms.
One aspect that Richards and team are already eyeing is a top-down predictive function, in which signals from higher levels directly influence how lower levels respond to input.
Feedback from upper levels doesn’t just provide error signals; it could also be nudging lower processing neurons towards a “better” activity pattern in real-time, says Richards.
The network doesn’t yet outperform other non-biologically derived (but “brain-inspired”) deep networks. But that’s not the point.
“Deep learning has had a huge impact on AI, but, to date, its impact on neuroscience has been limited,” the authors say.
Now neuroscientists have a lead they could experimentally test: that the structure of neurons underlie nature’s own deep learning algorithm.
“What we might see in the next decade or so is a real virtuous cycle of research between neuroscience and AI, where neuroscience discoveries help us to develop new AI and AI can help us interpret and understand our experimental data in neuroscience,” says Richards.
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