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They say size isn’t everything, but when it comes to delta robots it seems like it’s pretty important.
The speed and precision of these machines sees them employed in delicate pick-and-place tasks in all kinds of factories, as well as to control 3D printer heads. But Harvard researchers have found that scaling them down to millimeter scale makes them even faster and more precise, opening up applications in everything from microsurgery to manipulating tiny objects like circuit board components or even living cells.
Unlike the industrial robots you’re probably more familiar with, delta robots consist of three individually controlled arms supporting a platform. Different combinations of movements can move the platform in three directions, and a variety of tools can be attached to this platform.
The benefit of this design is that unlike a typical robotic arm, all the motors are housed at the base rather than at the joints, which reduces their mechanical complexity, but also—importantly—the weight of the arms. That means they can move and accelerate faster and with greater precision.
It’s been known for a while that the physics of these robots means the smaller you can make them, the more pronounced these advantages become, but scientists had struggled to build them at scales below tens of centimeters.
In a recent paper in the journal Science Robotics, the researchers describe how they used an origami-inspired micro-fabrication approach that relies on folding flat sheets of composite materials to create a robot measuring just 15 millimeters by 15 millimeters by 20 millimeters.
The robot dubbed “milliDelta” features joints that rely on a flexible polymer core to bend—a simplified version of the more complicated joints found in large-scale delta robots. The machine was powered by three piezoelectric actuators, which flex when a voltage is applied, and could perform movements at frequencies 15 to 20 times higher than current delta robots, with precisions down to roughly 5 micrometers.
One potential use for the device is to cancel out surgeons’ hand tremors as they carry out delicate microsurgery procedures, such as operations on the eye’s retina. The researchers actually investigated this application in their paper. They got volunteers to hold a toothpick and measured the movement of the tip to map natural hand tremors. They fed this data to the milliDelta, which was able to match the movements and therefore cancel them out.
In an email to Singularity Hub, the researchers said that adding the robot to the end of a surgical tool could make it possible to stabilize needles or scalpels, though this would require some design optimization. For a start, the base would have to be redesigned to fit on a surgical tool, and sensors would have to be added to the robot to allow it to measure tremors in real time.
Another promising application for the device would be placing components on circuit boards at very high speeds, which could prove valuable in electronics manufacturing. The researchers even think the device’s precision means it could be used for manipulating living cells in research and clinical laboratories.
The researchers even said it would be feasible to integrate the devices onto microrobots to give them similarly impressive manipulation capabilities, though that would require considerable work to overcome control and sensing challenges.
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The first time Dr. Blake Richards heard about deep learning, he was convinced that he wasn’t just looking at a technique that would revolutionize artificial intelligence. He also knew he was looking at something fundamental about the human brain.
That was the early 2000s, and Richards was taking a course with Dr. Geoff Hinton at the University of Toronto. Hinton, a pioneer architect of the algorithm that would later take the world by storm, was offering an introductory course on his learning method inspired by the human brain.
The key words here are “inspired by.” Despite Richards’ conviction, the odds were stacked against him. The human brain, as it happens, seems to lack a critical function that’s programmed into deep learning algorithms. On the surface, the algorithms were violating basic biological facts already proven by neuroscientists.
But what if, superficial differences aside, deep learning and the brain are actually compatible?
Now, in a new study published in eLife, Richards, working with DeepMind, proposed a new algorithm based on the biological structure of neurons in the neocortex. Also known as the cortex, this outermost region of the brain is home to higher cognitive functions such as reasoning, prediction, and flexible thought.
The team networked their artificial neurons together into a multi-layered network and challenged it with a classic computer vision task—identifying hand-written numbers.
The new algorithm performed well. But the kicker is that it analyzed the learning examples in a way that’s characteristic of deep learning algorithms, even though it was completely based on the brain’s fundamental biology.
“Deep learning is possible in a biological framework,” concludes the team.
Because the model is only a computer simulation at this point, Richards hopes to pass the baton to experimental neuroscientists, who could actively test whether the algorithm operates in an actual brain.
If so, the data could then be passed back to computer scientists to work out the next generation of massively parallel and low-energy algorithms to power our machines.
It’s a first step towards merging the two fields back into a “virtuous circle” of discovery and innovation.
The blame game
While you’ve probably heard of deep learning’s recent wins against humans in the game of Go, you might not know the nitty-gritty behind the algorithm’s operations.
In a nutshell, deep learning relies on an artificial neural network with virtual “neurons.” Like a towering skyscraper, the network is structured into hierarchies: lower-level neurons process aspects of an input—for example, a horizontal or vertical stroke that eventually forms the number four—whereas higher-level neurons extract more abstract aspects of the number four.
To teach the network, you give it examples of what you’re looking for. The signal propagates forward in the network (like climbing up a building), where each neuron works to fish out something fundamental about the number four.
Like children trying to learn a skill the first time, initially the network doesn’t do so well. It spits out what it thinks a universal number four should look like—think a Picasso-esque rendition.
But here’s where the learning occurs: the algorithm compares the output with the ideal output, and computes the difference between the two (dubbed “error”). This error is then “backpropagated” throughout the entire network, telling each neuron: hey, this is how far off you were, so try adjusting your computation closer to the ideal.
Millions of examples and tweakings later, the network inches closer to the desired output and becomes highly proficient at the trained task.
This error signal is crucial for learning. Without efficient “backprop,” the network doesn’t know which of its neurons are off kilter. By assigning blame, the AI can better itself.
The brain does this too. How? We have no clue.
What’s clear, though, is that the deep learning solution doesn’t work.
Backprop is a pretty needy function. It requires a very specific infrastructure for it to work as expected.
For one, each neuron in the network has to receive the error feedback. But in the brain, neurons are only connected to a few downstream partners (if that). For backprop to work in the brain, early-level neurons need to be able to receive information from billions of connections in their downstream circuits—a biological impossibility.
And while certain deep learning algorithms adapt a more local form of backprop— essentially between neurons—it requires their connection forwards and backwards to be symmetric. This hardly ever occurs in the brain’s synapses.
More recent algorithms adapt a slightly different strategy, in that they implement a separate feedback pathway that helps the neurons to figure out errors locally. While it’s more biologically plausible, the brain doesn’t have a separate computational network dedicated to the blame game.
What it does have are neurons with intricate structures, unlike the uniform “balls” that are currently applied in deep learning.
The team took inspiration from pyramidal cells that populate the human cortex.
“Most of these neurons are shaped like trees, with ‘roots’ deep in the brain and ‘branches’ close to the surface,” says Richards. “What’s interesting is that these roots receive a different set of inputs than the branches that are way up at the top of the tree.”
This is an illustration of a multi-compartment neural network model for deep learning. Left: Reconstruction of pyramidal neurons from mouse primary visual cortex. Right: Illustration of simplified pyramidal neuron models. Image Credit: CIFAR
Curiously, the structure of neurons often turn out be “just right” for efficiently cracking a computational problem. Take the processing of sensations: the bottoms of pyramidal neurons are right smack where they need to be to receive sensory input, whereas the tops are conveniently placed to transmit feedback errors.
Could this intricate structure be evolution’s solution to channeling the error signal?
The team set up a multi-layered neural network based on previous algorithms. But rather than having uniform neurons, they gave those in middle layers—sandwiched between the input and output—compartments, just like real neurons.
When trained with hand-written digits, the algorithm performed much better than a single-layered network, despite lacking a way to perform classical backprop. The cell-like structure itself was sufficient to assign error: the error signals at one end of the neuron are naturally kept separate from input at the other end.
Then, at the right moment, the neuron brings both sources of information together to find the best solution.
There’s some biological evidence for this: neuroscientists have long known that the neuron’s input branches perform local computations, which can be integrated with signals that propagate backwards from the so-called output branch.
However, we don’t yet know if this is the brain’s way of dealing blame—a question that Richards urges neuroscientists to test out.
What’s more, the network parsed the problem in a way eerily similar to traditional deep learning algorithms: it took advantage of its multi-layered structure to extract progressively more abstract “ideas” about each number.
“[This is] the hallmark of deep learning,” the authors explain.
The Deep Learning Brain
Without doubt, there will be more twists and turns to the story as computer scientists incorporate more biological details into AI algorithms.
One aspect that Richards and team are already eyeing is a top-down predictive function, in which signals from higher levels directly influence how lower levels respond to input.
Feedback from upper levels doesn’t just provide error signals; it could also be nudging lower processing neurons towards a “better” activity pattern in real-time, says Richards.
The network doesn’t yet outperform other non-biologically derived (but “brain-inspired”) deep networks. But that’s not the point.
“Deep learning has had a huge impact on AI, but, to date, its impact on neuroscience has been limited,” the authors say.
Now neuroscientists have a lead they could experimentally test: that the structure of neurons underlie nature’s own deep learning algorithm.
“What we might see in the next decade or so is a real virtuous cycle of research between neuroscience and AI, where neuroscience discoveries help us to develop new AI and AI can help us interpret and understand our experimental data in neuroscience,” says Richards.
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Artificial intelligence has received its fair share of hype recently. However, it’s hype that’s well-founded: IDC predicts worldwide spend on AI and cognitive computing will culminate to a whopping $46 billion (with a “b”) by 2020, and all the tech giants are jumping on board faster than you can say “ROI.” But what is AI, exactly?
According to Hilary Mason, AI today is being misused as a sort of catch-all term to basically describe “any system that uses data to do anything.” But it’s so much more than that. A truly artificially intelligent system is one that learns on its own, one that’s capable of crunching copious amounts of data in order to create associations and intelligently mimic actual human behavior.
It’s what powers the technology anticipating our next online purchase (Amazon), or the virtual assistant that deciphers our voice commands with incredible accuracy (Siri), or even the hipster-friendly recommendation engine that helps you discover new music before your friends do (Pandora). But AI is moving past these consumer-pleasing “nice-to-haves” and getting down to serious business: saving our butts.
Much in the same way robotics entered manufacturing, AI is making its mark in healthcare by automating mundane, repetitive tasks. This is especially true in the case of detecting cancer. By leveraging the power of deep learning, algorithms can now be trained to distinguish between sets of pixels in an image that represents cancer versus sets that don’t—not unlike how Facebook’s image recognition software tags pictures of our friends without us having to type in their names first. This software can then go ahead and scour millions of medical images (MRIs, CT scans, etc.) in a single day to detect anomalies on a scope that humans just aren’t capable of. That’s huge.
As if that wasn’t enough, these algorithms are constantly learning and evolving, getting better at making these associations with each new data set that gets fed to them. Radiology, dermatology, and pathology will experience a giant upheaval as tech giants and startups alike jump in to bring these deep learning algorithms to a hospital near you.
In fact, some already are: the FDA recently gave their seal of approval for an AI-powered medical imaging platform that helps doctors analyze and diagnose heart anomalies. This is the first time the FDA has approved a machine learning application for use in a clinical setting.
But how efficient is AI compared to humans, really? Well, aside from the obvious fact that software programs don’t get bored or distracted or have to check Facebook every twenty minutes, AI is exponentially better than us at analyzing data.
Take, for example, IBM’s Watson. Watson analyzed genomic data from both tumor cells and healthy cells and was ultimately able to glean actionable insights in a mere 10 minutes. Compare that to the 160 hours it would have taken a human to analyze that same data. Diagnoses aside, AI is also being leveraged in pharmaceuticals to aid in the very time-consuming grunt work of discovering new drugs, and all the big players are getting involved.
But AI is far from being just a behind-the-scenes player. Gartner recently predicted that by 2025, 50 percent of the population will rely on AI-powered “virtual personal health assistants” for their routine primary care needs. What this means is that consumer-facing voice and chat-operated “assistants” (think Siri or Cortana) would, in effect, serve as a central hub of interaction for all our connected health devices and the algorithms crunching all our real-time biometric data. These assistants would keep us apprised of our current state of well-being, acting as a sort of digital facilitator for our personal health objectives and an always-on health alert system that would notify us when we actually need to see a physician.
Slowly, and thanks to the tsunami of data and advancements in self-learning algorithms, healthcare is transitioning from a reactive model to more of a preventative model—and it’s completely upending the way care is delivered. Whether Elon Musk’s dystopian outlook on AI holds any weight or not is yet to be determined. But one thing’s certain: for the time being, artificial intelligence is saving our lives.
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