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#439077 How Scientists Grew Human Muscles in Pig ...

Posted on April 7, 2021 by Android

The little pigs bouncing around the lab looked exceedingly normal. Yet their adorable exterior hid a remarkable secret: each piglet carried two different sets of genes. For now, both sets came from their own species. But one day, one of those sets may be human.

The piglets are chimeras—creatures with intermingled sets of genes, as if multiple entities were seamlessly mashed together. Named after the Greek lion-goat-serpent monsters, chimeras may hold the key to an endless supply of human organs and tissues for transplant. The crux is growing these human parts in another animal—one close enough in size and function to our own.

Last week, a team from the University of Minnesota unveiled two mind-bending chimeras. One was joyous little piglets, each propelled by muscles grown from a different pig. Another was pig embryos, transplanted into surrogate pigs, that developed human muscles for more than 20 days.

The study, led by Drs. Mary and Daniel Garry at the University of Minnesota, had a therapeutic point: engineering a brilliant way to replace muscle loss, especially for the muscles around our skeletons that allow us to move and navigate the world. Trauma and injury, such as from firearm wounds or car crashes, can damage muscle tissue beyond the point of repair. Unfortunately, muscles are also stubborn in that donor tissue from cadavers doesn’t usually “take” at the injury site. For now, there are no effective treatments for severe muscle death, called volumetric muscle loss.

The new human-pig hybrids are designed to tackle this problem. Muscle wasting aside, the study also points to a clever “hack” that increases the amount of human tissue inside a growing pig embryo.

If further improved, the technology could “provide an unlimited supply of organs for transplantation,” said Dr. Mary Garry to Inverse. What’s more, because the human tissue can be sourced from patients themselves, the risk of rejection by the immune system is relatively low—even when grown inside a pig.

“The shortage of organs for heart transplantation, vascular grafting, and skeletal muscle is staggering,” said Garry. Human-animal chimeras could have a “seismic impact” that transforms organ transplantation and helps solve the organ shortage crisis.

That is, if society accepts the idea of a semi-humanoid pig.

Wait…But How?
The new study took a page from previous chimera recipes.

The main ingredients and steps go like this: first, you need an embryo that lacks the ability to develop a tissue or organ. This leaves an “empty slot” of sorts that you can fill with another set of genes—pig, human, or even monkey.

Second, you need to fine-tune the recipe so that the embryos “take” the new genes, incorporating them into their bodies as if they were their own. Third, the new genes activate to instruct the growing embryo to make the necessary tissue or organs without harming the overall animal. Finally, the foreign genes need to stay put, without cells migrating to another body part—say, the brain.

Not exactly straightforward, eh? The piglets are technological wonders that mix cutting-edge gene editing with cloning technologies.

The team went for two chimeras: one with two sets of pig genes, the other with a pig and human mix. Both started with a pig embryo that can’t make its own skeletal muscles (those are the muscles surrounding your bones). Using CRISPR, the gene-editing Swiss Army Knife, they snipped out three genes that are absolutely necessary for those muscles to develop. Like hitting a bullseye with three arrows simultaneously, it’s already a technological feat.

Here’s the really clever part: the muscles around your bones have a slightly different genetic makeup than the ones that line your blood vessels or the ones that pump your heart. While the resulting pig embryos had severe muscle deformities as they developed, their hearts beat as normal. This means the gene editing cut only impacted skeletal muscles.

Then came step two: replacing the missing genes. Using a microneedle, the team injected a fertilized and slightly developed pig egg—called a blastomere—into the embryo. If left on its natural course, a blastomere eventually develops into another embryo. This step “smashes” the two sets of genes together, with the newcomer filling the muscle void. The hybrid embryo was then placed into a surrogate, and roughly four months later, chimeric piglets were born.

Equipped with foreign DNA, the little guys nevertheless seemed totally normal, nosing around the lab and running everywhere without obvious clumsy stumbles. Under the microscope, their “xenomorph” muscles were indistinguishable from run-of-the-mill average muscle tissue—no signs of damage or inflammation, and as stretchy and tough as muscles usually are. What’s more, the foreign DNA seemed to have only developed into muscles, even though they were prevalent across the body. Extensive fishing experiments found no trace of the injected set of genes inside blood vessels or the brain.

A Better Human-Pig Hybrid
Confident in their recipe, the team next repeated the experiment with human cells, with a twist. Instead of using controversial human embryonic stem cells, which are obtained from aborted fetuses, they relied on induced pluripotent stem cells (iPSCs). These are skin cells that have been reverted back into a stem cell state.

Unlike previous attempts at making human chimeras, the team then scoured the genetic landscape of how pig and human embryos develop to find any genetic “brakes” that could derail the process. One gene, TP53, stood out, which was then promptly eliminated with CRISPR.

This approach provides a way for future studies to similarly increase the efficiency of interspecies chimeras, the team said.

The human-pig embryos were then carefully grown inside surrogate pigs for less than a month, and extensively analyzed. By day 20, the hybrids had already grown detectable human skeletal muscle. Similar to the pig-pig chimeras, the team didn’t detect any signs that the human genes had sprouted cells that would eventually become neurons or other non-muscle cells.

For now, human-animal chimeras are not allowed to grow to term, in part to stem the theoretical possibility of engineering humanoid hybrid animals (shudder). However, a sentient human-pig chimera is something that the team specifically addressed. Through multiple experiments, they found no trace of human genes in the embryos’ brain stem cells 20 and 27 days into development. Similarly, human donor genes were absent in cells that would become the hybrid embryos’ reproductive cells.

Despite bioethical quandaries and legal restrictions, human-animal chimeras have taken off, both as a source of insight into human brain development and a well of personalized organs and tissues for transplant. In 2019, Japan lifted its ban on developing human brain cells inside animal embryos, as well as the term limit—to global controversy. There’s also the question of animal welfare, given that hybrid clones will essentially become involuntary organ donors.

As the debates rage on, scientists are nevertheless pushing the limits of human-animal chimeras, while treading as carefully as possible.

“Our data…support the feasibility of the generation of these interspecies chimeras, which will serve as a model for translational research or, one day, as a source for xenotransplantation,” the team said.

Image Credit: Christopher Carson on Unsplash Continue reading →

Posted in Human Robots

#439055 Stretch Is Boston Dynamics’ Take on a ...

Posted on April 2, 2021 by Android

Today, Boston Dynamics is announcing Stretch, a mobile robot designed to autonomously move boxes around warehouses. At first glance, you might be wondering why the heck this is a Boston Dynamics robot at all, since the dynamic mobility that we associate with most of their platforms is notably absent. The combination of strength and speed in Stretch’s arm is something we haven’t seen before in a mobile robot, and it’s what makes this a unique and potentially exciting entry into the warehouse robotics space.

Useful mobile manipulation in any environment that’s not almost entirely structured is still a significant challenge in robotics, and it requires a very difficult combination of sensing, intelligence, and dynamic motion, all of which are classic Boston Dynamics. But also classic Boston Dynamics is building really cool platforms, and only later trying to figure out a way of making them commercially viable. So why Stretch, why boxes, why now, and (the real question) why not Handle? We talk with Boston Dynamics’ Vice President of Product Engineering Kevin Blankespoor to find out.

Stretch is very explicitly a box-handling mobile robot for relatively well structured warehouses. It’s in no way designed to be a generalist that many of Boston Dynamics’ other robots are. And to be fair, this is absolutely how to make a robot that’s practical and cost effective right out of the crate: Identify a task that is dull or dirty or dangerous for humans, design a robot to do that task safely and efficiently, and deploy it with the expectation that it’ll be really good at that task but not necessarily much else. This is a very different approach than a robot like Spot, where the platform came first and the practical applications came later—with Stretch, it’s all about that specific task in a specific environment.

There are already robotic solutions for truck unloading, palletizing, and depalletizing, but Stretch seems to be uniquely capable. For truck unloading, the highest performance systems that I’m aware of are monstrous things (here’s one example from Honeywell) that use a ton of custom hardware to just sort of ingest the cargo within a trailer all at once. In a highly structured and predictable warehouse, this sort of thing may pay off over the long term, but it’s going to be extremely expensive and not very versatile at all.

Palletizing and depalletizing robots are much more common in warehouses today. They’re almost always large industrial arms surrounded by a network of custom conveyor belts and whatnot, suffering from the same sorts of constraints as a truck unloader— very capable in some situations, but generally high cost and low flexibility.

Photo: Boston Dynamics

Stretch is probably not going to be able to compete with either of these types of dedicated systems when it comes to sheer speed, but it offers lots of other critical advantages: It’s fast and easy to deploy, easy to use, and adaptable to a variety of different tasks without costly infrastructure changes. It’s also very much not Handle, which was Boston Dynamics’ earlier (although not that much earlier) attempt at a box-handling robot for warehouses, and (let’s be honest here) a much more Boston Dynamics-y thing than Stretch seems to be. To learn more about why the answer is Stretch rather than Handle, and how Stretch will fit into the warehouse of the very near future, we spoke with Kevin Blankespoor, Boston Dynamics’ VP of Product Engineering and chief engineer for both Handle and Stretch.

IEEE Spectrum: Tell me about Stretch!

Kevin Blankespoor: Stretch is the first mobile robot that we’ve designed specifically for the warehouse. It’s all about moving boxes. Stretch is a flexible robot that can move throughout the warehouse and do different tasks. During a typical day in the life of Stretch in the future, it might spend the morning on the inbound side of the warehouse unloading boxes from trucks. It might spend the afternoon in the aisles of the warehouse building up pallets to go to retailers and e-commerce facilities, and it might spend the evening on the outbound side of the warehouse loading boxes into the trucks. So, it really goes to where the work is.

There are already other robots that include truck unloading robots, palletizing and depalletizing robots, and mobile bases with arms on them. What makes Boston Dynamics the right company to introduce a new robot in this space?

We definitely thought through this, because there are already autonomous mobile robots [AMRs] out there. Most of them, though, are more like pallet movers or tote movers—they don't have an arm, and most of them are really just about moving something from point A to point B without manipulation capability. We've seen some experiments where people put arms on AMRs, but nothing that's made it very far in the market. And so when we started looking at Stretch, we realized we really needed to make a custom robot, and that it was something we could do quickly.

“We got a lot of interest from people who wanted to put Atlas to work in the warehouse, but we knew that we could build a simpler robot to do some of those same tasks.”

Stretch is built with pieces from Spot and Atlas and that gave us a big head start. For example, if you look at Stretch’s vision system, it's 2D cameras, depth sensors, and software that allows it to do obstacle detection, box detection, and localization. Those are all the same sensors and software that we've been using for years on our legged robots. And if you look closely at Stretch’s wrist joints, they're actually the same as Spot’s hips. They use the same electric motors, the same gearboxes, the same sensors, and they even have the same closed-loop controller controlling the joints.

If you were to buy an existing industrial robot arm with this kind of performance, it would be about four times heavier than the arm we built, and it's really hard to make that into a mobile robot. A lot of this came from our leg technology because it’s so important for our leg designs to be lightweight for the robots to balance. We took that same strength to weight advantage that we have, and built it into this arm. We're able to rapidly piece together things from our other robots to get us out of the gate quickly, so even though this looks like a totally different robot, we think we have a good head start going into this market.

At what point did you decide to go with an arm on a statically stable base on Stretch, rather than something more, you know, dynamic-y?

Stretch looks really different than the robots that Boston Dynamics has done in the past. But you'd be surprised how much similarity there is between our legged robots and Stretch under the hood. Looking back, we actually got our start on moving boxes with Atlas, and at that point it was just research and development. We were really trying to do force control for box grasping. We were picking up heavy boxes and maintaining balance and working on those fundamentals. We released a video of that as our first next-gen Atlas video, and it was interesting. We got a lot of interest from people who wanted to put Atlas to work in the warehouse, but we knew that we could build a simpler robot to do some of those same tasks.

So at this point we actually came up with Handle. The intent of Handle was to do a couple things—one was, we thought we could build a simpler robot that had Atlas’ attributes. Handle has a small footprint so it can fit in tight spaces, but it can pick up heavy boxes. And in addition to that, we had always really wanted to combine wheels and legs. We’d been talking about doing that for a decade and so Handle was a chance for us to try it.

We built a couple versions of Handle, and the first one was really just a prototype to kind of explore the morphology. But the second one was more purpose-built for warehouse tasks, and we started building pallets with that one and it looked pretty good. And then we started doing truck unloading with Handle, which was the pivotal moment. Handle could do it, but it took too long. Every time Handle grasped a box, it would have to roll back and then get to a place where it could spin itself to face forward and place the box, and trucks are very tight for a robot this size, so there's not a lot of room to maneuver. We knew the whole time that there was a robot like Stretch that was another alternative, but that's really when it became clear that Stretch would have a lot of advantages, and we started working on it about a year ago.

Stretch is certainly impressive in a practical way, but I’ll admit to really hoping that something like Handle could have turned out to be a viable warehouse robot.

I love the Handle project as well, and I’m very passionate about that robot. And there was a stage before we built Stretch where we thought, “this would be pretty standard looking compared to Handle, is it going to capture enough of the Boston Dynamics secret sauce?” But when you actually dissect all the problems within Stretch that you have to tackle, there are a lot of cool robotics problems left in there—the vision system, the planning, the manipulation, the grasping of the boxes—it's a lot harder to solve than it looks, and we're excited that we're actually getting fairly far down that road now.

What happens to Handle now?

Stretch has really taken over our team as far as warehouse products go. Handle we still use occasionally as a research robot, but it’s not actively under development. Stretch is really Handle’s descendent. Handle’s not retired, exactly, but we’re just using it for things like the dance video.

There’s still potential to do cool stuff with Handle. I do think that combining wheels with legs is very cool, and largely unexplored compared to its potential. So I still think that you're gonna see versions of robots combining wheels and legs like Handle, and maybe a version of Handle in the future that does more of that. But because we're switching this thread from research into product, Stretch is really the main focus now.

How autonomous is Stretch?

Stretch is semi-autonomous, and that means it really needs to work with people to tap into its full potential. With truck unloading, for example, a person will drive Stretch into the back of the truck and then basically point Stretch in the right direction and say go. And from that point on, everything’s autonomous. Stretch has its vision system and its mobility and it can detect all the boxes, grasp all boxes, and move them onto a conveyor all autonomously. This is something that takes people hours to do manually, and Stretch can go all the way until it gets to the last box, and the truck is empty. There are some parts of the truck unloading task that do require people, like verifying that the truck is in the right place and opening the doors. But this takes a person just a few minutes, and then the robot can spend hours or as long as it takes to do its job autonomously.

There are also other tasks in the warehouse where the autonomy will increase in the future. After truck unloading, the second thing we’ll take on is order building, which will be more in the aisles of a warehouse. For that, Stretch will be navigating around the warehouse, finding the right pallet it needs to take a box from, and loading it onto a new pallet. This will be a different model with more autonomy; you’ll still have people involved to some degree, but the robot will have a higher percentage of the time where it can work independently.

What kinds of constraints is Stretch operating under? Do the boxes all have to be stacked neatly in the back of the truck, do they have to be the same size, the same color, etc?

“This will be a different model with more autonomy. You’ll still have people involved to some degree, but the robot will have a higher percentage of the time where it can work independently.”

If you think about manufacturing, where there's been automation for decades, you can go into a modern manufacturing facility and there are robot arms and conveyors and other machines. But if you look at the actual warehouse space, 90+ percent is manually operated, and that's because of what you just asked about— things that are less structured, where there’s more variety, and it's more challenging for a robot. But this is starting to change. This is really, really early days, and you’re going to be seeing a lot more robots in the warehouse space.

The warehouse robotics industry is going to grow a lot over the next decade, and a lot of that boils down to vision—the ability for robots to navigate and to understand what they’re seeing. Actually seeing boxes in real world scenarios is challenging, especially when there's a lot of variety. We've been testing our machine learning-based box detection system on Pick for a few years now, and it's gotten far enough that we know it’s one of the technical hurdles you need to overcome to succeed in the warehouse.

Can you compare the performance of Stretch to the performance of a human in a box-unloading task?

Stretch can move cases up to 50 pounds which is the OSHA limit for how much a single person's allowed to move. The peak case rate for Stretch is 800 cases per hour. You really need to keep up with the flow of goods throughout the warehouse, and 800 cases per hour should be enough for most applications. This is similar to a really good human; most humans are probably slower, and it’s hard for a human to sustain that rate, and one of the big issues with people doing this jobs is injury rates. Imagine moving really heavy boxes all day, and having to reach up high or bend down to get them—injuries are really common in this area. Truck unloading is one of the hardest jobs in a warehouse, and that’s one of the reasons we’re starting there with Stretch.

Is Stretch safe for humans to be around?

We looked at using collaborative robot arms for Stretch, but they don’t have the combination of strength and speed and reach to do this task. That’s partially just due to the laws of physics—if you want to move a 50lb box really fast, that’s a lot of energy there. So, Stretch does need to maintain separation from humans, but it’s pretty safe when it’s operating in the back of a truck.

In the middle of a warehouse, Stretch will have a couple different modes. When it's traveling around it'll be kind of like an AMR, and use a safety-rated lidar making sure that it slows down or stops as people get closer. If it's parked and the arm is moving, it'll do the same thing, monitoring anyone getting close and either slow down or stop.

How do you see Stretch interacting with other warehouse robots?

For building pallet orders, we can do that in a couple of different ways, and we’re experimenting with partners in the AMR space. So you might have an AMR that moves the pallet around and then rendezvous with Stretch, and Stretch does the manipulation part and moves boxes onto the pallet, and then the AMR scuttles off to the next rendezvous point where maybe a different Stretch meets it. We’re developing prototypes of that behavior now with a few partners. Another way to do it is Stretch can actually pull the pallet around itself and do both tasks. There are two fundamental things that happen in the warehouse: there's movement of goods, and there's manipulation of goods, and Stretch can do both.

You’re aware that Hello Robot has a mobile manipulator called Stretch, right?

Great minds think alike! We know Aaron [Edsinger] from the Google days; we all used to be in the same company, and he’s a great guy. We’re in very different applications and spaces, though— Aaron’s robot is going into research and maybe a little bit into the consumer space, while this robot is on a much bigger scale aimed at industrial applications, so I think there’s actually a lot of space between our robots, in terms of how they’ll be used.

Editor’s Note: We did check in with Aaron Edsinger at Hello Robot, and he sees things a little bit differently. “We're disappointed they chose our name for their robot,” Edsinger told us. “We're seriously concerned about it and considering our options.” We sincerely hope that Boston Dynamics and Hello Robot can come to an amicable solution on this.
What’s the timeline for commercial deployment of Stretch?

This is a prototype of the Stretch robot, and anytime we design a new robot, we always like to build a prototype as quickly as possible so we can figure out what works and what doesn't work. We did that with our bipeds and quadrupeds as well. So, we get an early look at what we need to iterate, because any time you build the first thing, it's not the right thing, and you always need to make changes to get to the final version. We've got about six of those Stretch prototypes operating now. In parallel, our hardware team is finishing up the design of the productized version of Stretch. That version of Stretch looks a lot like the prototype, but every component has been redesigned from the ground up to be manufacturable, to be reliable, and to be higher performance.

For the productized version of Stretch, we’ll build up the first units this summer, and then it’ll go on sale next year. So this is kind of a sneak peak into what the final product will be.

How much does it cost, and will you be selling Stretch, or offering it as a service?

We’re not quite ready to talk about cost yet, but it’ll be cost effective, and similar in cost to existing systems if you were to combine an industrial robot arm, custom gripper, and mobile base. We’re considering both selling and leasing as a service, but we’re not quite ready to narrow it down yet.

Photo: Boston Dynamics

As with all mobile manipulators, what Stretch can do long-term is constrained far more by software than by hardware. With a fast and powerful arm, a mobile base, a solid perception system, and 16 hours of battery life, you can imagine how different grippers could enable all kinds of different capabilities. But we’re getting ahead of ourselves, because it’s a long, long way from getting a prototype to work pretty well to getting robots into warehouses in a way that’s commercially viable long-term, even when the use case is as clear as it seems to be for Stretch.

Stretch also could signal a significant shift in focus for Boston Dynamics. While Blankespoor’s comments about Stretch leveraging Boston Dynamics’ expertise with robots like Spot and Atlas are well taken, Stretch is arguably the most traditional robot that the company has designed, and they’ve done so specifically to be able to sell robots into industry. This is what you do if you’re a robotics company who wants to make money by selling robots commercially, which (historically) has not been what Boston Dynamics is all about. Despite its bonkers valuation, Boston Dynamics ultimately needs to make money, and robots like Stretch are a good way to do it. With that in mind, I wouldn’t be surprised to see more robots like this from Boston Dynamics—robots that leverage the company’s unique technology, but that are designed to do commercially useful tasks in a somewhat less flashy way. And if this strategy keeps Boston Dynamics around (while funding some occasional creative craziness), then I’m all for it. Continue reading →

Posted in Human Robots

#439012 Video Friday: Man-Machine Synergy ...

Posted on March 20, 2021 by Android

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

RoboSoft 2021 – April 12-16, 2021 – [Online Conference]
ICRA 2021 – May 30-5, 2021 – Xi'an, China
DARPA SubT Finals – September 21-23, 2021 – Louisville, KY, USA
WeRobot 2021 – September 23-25, 2021 – Coral Gables, FL, USA
Let us know if you have suggestions for next week, and enjoy today's videos.

Man-Machine Synergy Effectors, Inc. is a Japanese company working on an absolutely massive “human machine synergistic effect device,” which is a huge robot controlled by a nearby human using a haptic rig.

From the look of things, the next generation will be able to move around. Whoa.

[ MMSE ]

This method of loading and unloading AMRs without having them ever stop moving is so obvious that there must be some equally obvious reason why I've never seen it done in practice.

The LoadRunner is able to transport and sort parcels weighing up to 30 kilograms. This makes it the perfect luggage carrier for airports. These AI-driven go-carts can also work in concert as larger collectives to carry large, heavy and bulky objects. Every LoadRunner can also haul up to four passive trailers. Powered by four electric motors, the LoadRunner sharply brakes at just the right moment right in front of its destination and the payload slides from the robot onto the delivery platform.

[ Fraunhofer ] via [ Gizmodo ]

Ayato Kanada at Kyushu University wrote in to share this clever “dislocatable joint,” a way of combining continuum and rigid robots.

[ Paper ]

Thanks Ayato!

The DodgeDrone challenge revisits the popular dodgeball game in the context of autonomous drones. Specifically, participants will have to code navigation policies to fly drones between waypoints while avoiding dynamic obstacles. Drones are fast but fragile systems: as soon as something hits them, they will crash! Since objects will move towards the drone with different speeds and acceleration, smart algorithms are required to avoid them!

This could totally happen in real life, and we need to be prepared for it!

[ DodgeDrone Challenge ]

In addition to winning the Best Student Design Competition CREATIVITY Award at HRI 2021, this paper would also have won the Best Paper Title award, if that award existed.

[ Paper ]

Robots are traditionally bound by a fixed morphology during their operational lifetime, which is limited to adapting only their control strategies. Here we present the first quadrupedal robot that can morphologically adapt to different environmental conditions in outdoor, unstructured environments.

We show that the robot exploits its training to effectively transition between different morphological configurations, exhibiting substantial performance improvements over a non-adaptive approach. The demonstrated benefits of real-world morphological adaptation demonstrate the potential for a new embodied way of incorporating adaptation into future robotic designs.

[ Nature ]

A drone video shot in a Minneapolis bowling alley was hailed as an instant classic. One Hollywood veteran said it “adds to the language and vocabulary of cinema.” One IEEE Spectrum editor said “hey that's pretty cool.”

[ Bryant Lake Bowl ]

It doesn't take a robot to convince me to buy candy, but I think if I buy candy from Relay it's a business expense, right?

[ RIS ]

DARPA is making progress on its AI dogfighting program, with physical flight tests expected this year.

[ DARPA ACE ]

Unitree Robotics has realized that the Empire needs to be overthrown!

[ Unitree ]

Windhover Labs, an emerging leader in open and reliable flight software and hardware, announces the upcoming availability of its first hardware product, a low cost modular flight computer for commercial drones and small satellites.

[ Windhover ]

As robots and autonomous systems are poised to become part of our everyday lives, the University of Michigan and Ford are opening a one-of-a-kind facility where they’ll develop robots and roboticists that help make lives better, keep people safer and build a more equitable society.

[ U Michigan ]

The adaptive robot Rizon combined with a new hybrid electrostatic and gecko-inspired gripping pad developed by Stanford BDML can manipulate bulky, non-smooth items in the most effort-saving way, which broadens the applications in retail and household environments.

[ Flexiv ]

Thanks Yunfan!

I don't know why anyone would want things to get MORE icy, but if you do for some reason, you can make it happen with a Husky.

Is winter over yet?

[ Clearpath ]

Skip ahead to about 1:20 to see a pair of Gita robots following a Spot following a human like a chain of lil’ robot duckings.

[ PFF ]

Here are a couple of retro robotics videos, one showing teleoperated humanoids from 2000, and the other showing a robotic guide dog from 1976 (!)

[ Tachi Lab ]

Thanks Fan!

If you missed Chad Jenkins' talk “That Ain’t Right: AI Mistakes and Black Lives” last time, here's another opportunity to watch from Robotics Today, and it includes a top notch panel discussion at the end.

[ Robotics Today ]

Since its founding in 1979, the Robotics Institute (RI) at Carnegie Mellon University has been leading the world in robotics research and education. In the mid 1990s, RI created NREC as the applied R&D center within the Institute with a specific mission to apply robotics technology in an impactful way on real-world applications. In this talk, I will go over numerous R&D programs that I have led at NREC in the past 25 years.

[ CMU ] Continue reading →

Posted in Human Robots

#438785 Video Friday: A Blimp For Your Cat

Posted on February 28, 2021 by Android

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

HRI 2021 – March 8-11, 2021 – [Online Conference]
RoboSoft 2021 – April 12-16, 2021 – [Online Conference]
ICRA 2021 – May 30-5, 2021 – Xi'an, China
Let us know if you have suggestions for next week, and enjoy today's videos.

Shiny robotic cat toy blimp!

I am pretty sure this is Google Translate getting things wrong, but the About page mentions that the blimp will “take you to your destination after appearing in the death of God.”

[ NTT DoCoMo ] via [ RobotStart ]

If you have yet to see this real-time video of Perseverance landing on Mars, drop everything and watch it.

During the press conference, someone commented that this is the first time anyone on the team who designed and built this system has ever seen it in operation, since it could only be tested at the component scale on Earth. This landing system has blown my mind since Curiosity.

Here's a better look at where Percy ended up:

[ NASA ]

The fact that Digit can just walk up and down wet, slippery, muddy hills without breaking a sweat is (still) astonishing.

[ Agility Robotics ]

SkyMul wants drones to take over the task of tying rebar, which looks like just the sort of thing we'd rather robots be doing so that we don't have to:

The tech certainly looks promising, and SkyMul says that they're looking for some additional support to bring things to the pilot stage.

[ SkyMul ]

Thanks Eohan!

Flatcat is a pet-like, playful robot that reacts to touch. Flatcat feels everything exactly: Cuddle with it, romp around with it, or just watch it do weird things of its own accord. We are sure that flatcat will amaze you, like us, and caress your soul.

I don't totally understand it, but I want it anyway.

[ Flatcat ]

Thanks Oswald!

This is how I would have a romantic dinner date if I couldn't get together in person. Herman the UR3 and an OptiTrack system let me remotely make a romantic meal!

[ Dave's Armoury ]

Here, we propose a novel design of deformable propellers inspired by dragonfly wings. The structure of these propellers includes a flexible segment similar to the nodus on a dragonfly wing. This flexible segment can bend, twist and even fold upon collision, absorbing force upon impact and protecting the propeller from damage.

[ Paper ]

Thanks Van!

In the 1970s, The CIA​ created the world's first miniaturized unmanned aerial vehicle, or UAV, which was intended to be a clandestine listening device. The Insectothopter was never deployed operationally, but was still revolutionary for its time.

It may never have been deployed (not that they'll admit to, anyway), but it was definitely operational and could fly controllably.

[ CIA ]

Research labs are starting to get Digits, which means we're going to get a much better idea of what its limitations are.

[ Ohio State ]

This video shows the latest achievements for LOLA walking on undetected uneven terrain. The robot is technically blind, not using any camera-based or prior information on the terrain.

[ TUM ]

We define “robotic contact juggling” to be the purposeful control of the motion of a three-dimensional smooth object as it rolls freely on a motion-controlled robot manipulator, or “hand.” While specific examples of robotic contact juggling have been studied before, in this paper we provide the first general formulation and solution method for the case of an arbitrary smooth object in single-point rolling contact on an arbitrary smooth hand.

[ Paper ]

Thanks Fan!

A couple of new cobots from ABB, designed to work safely around humans.

[ ABB ]

Thanks Fan!

It's worth watching at least a little bit of Adam Savage testing Spot's new arm, because we get to see Spot try, fail, and eventually succeed at an autonomous door-opening behavior at the 10 minute mark.

[ Tested ]

SVR discusses diversity with guest speakers Dr. Michelle Johnson from the GRASP Lab at UPenn; Dr Ariel Anders from Women in Robotics and first technical hire at Robust.ai; Alka Roy from The Responsible Innovation Project; and Kenechukwu C. Mbanesi and Kenya Andrews from Black in Robotics. The discussion here is moderated by Dr. Ken Goldberg—artist, roboticist and Director of the CITRIS People and Robots Lab—and Andra Keay from Silicon Valley Robotics.

[ SVR ]

RAS presents a Soft Robotics Debate on Bioinspired vs. Biohybrid Design.

In this debate, we will bring together experts in Bioinspiration and Biohybrid design to discuss the necessary steps to make more competent soft robots. We will try to answer whether bioinspired research should focus more on developing new bioinspired material and structures or on the integration of living and artificial structures in biohybrid designs.

[ RAS SoRo ]

IFRR presents a Colloquium on Human Robot Interaction.

Across many application domains, robots are expected to work in human environments, side by side with people. The users will vary substantially in background, training, physical and cognitive abilities, and readiness to adopt technology. Robotic products are expected to not only be intuitive, easy to use, and responsive to the needs and states of their users, but they must also be designed with these differences in mind, making human-robot interaction (HRI) a key area of research.

[ IFRR ]

Vijay Kumar, Nemirovsky Family Dean and Professor at Penn Engineering, gives an introduction to ENIAC day and David Patterson, Pardee Professor of Computer Science, Emeritus at the University of California at Berkeley, speaks about the legacy of the ENIAC and its impact on computer architecture today. This video is comprised of lectures one and two of nine total lectures in the ENIAC Day series.

There are more interesting ENIAC videos at the link below, but we'll highlight this particular one, about the women of the ENIAC, also known as the First Programmers.

[ ENIAC Day ] Continue reading →

Posted in Human Robots

#438755 Soft Legged Robot Uses Pneumatic ...

Posted on February 24, 2021 by Android

Soft robots are inherently safe, highly resilient, and potentially very cheap, making them promising for a wide array of applications. But development on them has been a bit slow relative to other areas of robotics, at least partially because soft robots can’t directly benefit from the massive increase in computing power and sensor and actuator availability that we’ve seen over the last few decades. Instead, roboticists have had to get creative to find ways of achieving the functionality of conventional robotics components using soft materials and compatible power sources.

In the current issue of Science Robotics, researchers from UC San Diego demonstrate a soft walking robot with four legs that moves with a turtle-like gait controlled by a pneumatic circuit system made from tubes and valves. This air-powered nervous system can actuate multiple degrees of freedom in sequence from a single source of pressurized air, offering a huge reduction in complexity and bringing a very basic form of decision making onto the robot itself.

Generally, when people talk about soft robots, the robots are only mostly soft. There are some components that are very difficult to make soft, including pressure sources and the necessary electronics to direct that pressure between different soft actuators in a way that can be used for propulsion. What’s really cool about this robot is that researchers have managed to take a pressure source (either a single tether or an onboard CO2 cartridge) and direct it to four different legs, each with three different air chambers, using an oscillating three valve circuit made entirely of soft materials.

Photo: UCSD

The pneumatic circuit that powers and controls the soft quadruped.

The inspiration for this can be found in biology—natural organisms, including quadrupeds, use nervous system components called central pattern generators (CPGs) to prompt repetitive motions with limbs that are used for walking, flying, and swimming. This is obviously more complicated in some organisms than in others, and is typically mediated by sensory feedback, but the underlying structure of a CPG is basically just a repeating circuit that drives muscles in sequence to produce a stable, continuous gait. In this case, we’ve got pneumatic muscles being driven in opposing pairs, resulting in a diagonal couplet gait, where diagonally opposed limbs rotate forwards and backwards at the same time.

Diagram: Science Robotics

(J) Pneumatic logic circuit for rhythmic leg motion. A constant positive pressure source (P+) applied to three inverter components causes a high-pressure state to propagate around the circuit, with a delay at each inverter. While the input to one inverter is high, the attached actuator (i.e., A1, A2, or A3) is inflated. This sequence of high-pressure states causes each pair of legs of the robot to rotate in a direction determined by the pneumatic connections. (K) By reversing the sequence of activation of the pneumatic oscillator circuit, the attached actuators inflate in a new sequence (A1, A3, and A2), causing (L) the legs of the robot to rotate in reverse. (M) Schematic bottom view of the robot with the directions of leg motions indicated for forward walking.

Diagram: Science Robotics

Each of the valves acts as an inverter by switching the normally closed half (top) to open and the normally open half (bottom) to closed.

The circuit itself is made up of three bistable pneumatic valves connected by tubing that acts as a delay by providing resistance to the gas moving through it that can be adjusted by altering the tube’s length and inner diameter. Within the circuit, the movement of the pressurized gas acts as both a source of energy and as a signal, since wherever the pressure is in the circuit is where the legs are moving. The simplest circuit uses only three valves, and can keep the robot walking in one single direction, but more valves can add more complex leg control options. For example, the researchers were able to use seven valves to tune the phase offset of the gait, and even just one additional valve (albeit of a slightly more complex design) could enable reversal of the system, causing the robot to walk backwards in response to input from a soft sensor. And with another complex valve, a manual (tethered) controller could be used for omnidirectional movement.

This work has some similarities to the rover that JPL is developing to explore Venus—that rover isn’t a soft robot, of course, but it operates under similar constraints in that it can’t rely on conventional electronic systems for autonomous navigation or control. It turns out that there are plenty of clever ways to use mechanical (or in this case, pneumatic) intelligence to make robots with relatively complex autonomous behaviors, meaning that in the future, soft (or soft-ish) robots could find valuable roles in situations where using a non-compliant system is not a good option.

For more on why we should be so excited about soft robots and just how soft a soft robot needs to be, we spoke with Michael Tolley, who runs the Bioinspired Robotics and Design Lab at UCSD, and Dylan Drotman, the paper’s first author.

IEEE Spectrum: What can soft robots do for us that more rigid robotic designs can’t?

Michael Tolley: At the very highest level, one of the fundamental assumptions of robotics is that you have rigid bodies connected at joints, and all your motion happens at these joints. That's a really nice approach because it makes the math easy, frankly, and it simplifies control. But when you look around us in nature, even though animals do have bones and joints, the way we interact with the world is much more complicated than that simple story. I’m interested in where we can take advantage of material properties in robotics. If you look at robots that have to operate in very unknown environments, I think you can build in some of the intelligence for how to deal with those environments into the body of the robot itself. And that’s the category this work really falls under—it's about navigating the world.

Dylan Drotman: Walking through confined spaces is a good example. With the rigid legged robot, you would have to completely change the way that the legs move to walk through a confined space, while if you have flexible legs, like the robot in our paper, you can use relatively simple control strategies to squeeze through an area you wouldn’t be able to get through with a rigid system.

How smart can a soft robot get?

Drotman: Right now we have a sensor on the front that's connected through a fluidic transmission to a bistable valve that causes the robot to reverse. We could add other sensors around the robot to allow it to change direction whenever it runs into an obstacle to effectively make an electronics-free version of a Roomba.

Tolley: Stepping back a little bit from that, one could make an argument that we’re using basic memory elements to generate very basic signals. There’s nothing in principle that would stop someone from making a pneumatic computer—it’s just very complicated to make something that complex. I think you could build on this and do more intelligent decision making, but using this specific design and the components we’re using, it’s likely to be things that are more direct responses to the environment.

How well would robots like these scale down?

Drotman: At the moment we’re manufacturing these components by hand, so the idea would be to make something more like a printed circuit board instead, and looking at how the channel sizes and the valve design would affect the actuation properties. We’ll also be coming up with new circuits, and different designs for the circuits themselves.

Tolley: Down to centimeter or millimeter scale, I don’t think you’d have fundamental fluid flow problems. I think you’re going to be limited more by system design constraints. You’ll have to be able to locomote while carrying around your pressure source, and possibly some other components that are also still rigid. When you start to talk about really small scales, though, it's not as clear to me that you really need an intrinsically soft robot. If you think about insects, their structural geometry can make them behave like they’re soft, but they’re not intrinsically soft.

Should we be thinking about soft robots and compliant robots in the same way, or are they fundamentally different?

Tolley: There’s certainly a connection between the two. You could have a compliant robot that behaves in a very similar way to an intrinsically soft robot, or a robot made of intrinsically soft materials. At that point, it comes down to design and manufacturing and practical limitations on what you can make. I think when you get down to small scales, the two sort of get connected.

There was some interesting work several years ago on using explosions to power soft robots. Is that still a thing?

Tolley: One of the opportunities with soft robots is that with material compliance, you have the potential to store energy. I think there’s exciting potential there for rapid motion with a soft body. Combustion is one way of doing that with power coming from a chemical source all at once, but you could also use a relatively weak muscle that over time stores up energy in a soft body and then releases it.

Is it realistic to expect complete softness from soft robots, or will they likely always have rigid components because they have to store or generate and move pressurized gas somehow?

Tolley: If you look in nature, you do have soft pumps like the heart, but although it’s soft, it’s still relatively stiff. Like, if you grab a heart, it’s not totally squishy. I haven’t done it, but I’d imagine. If you have a container that you’re pressurizing, it has to be stiff enough to not just blow up like a balloon. Certainly pneumatics or hydraulics are not the only way to go for soft actuators; there has been some really nice work on smart muscles and smart materials like hydraulic electrostatic (HASEL) actuators. They seem promising, but all of these actuators have challenges. We’ve chosen to stick with pressurized pneumatics in the near term; longer term, I think you’ll start to see more of these smart material actuators become more practical.

Personally, I don’t have any problem with soft robots having some rigid components. Most animals on land have some rigid components, but they can still take advantage of being soft, so it’s probably going to be a combination. But I do also like the vision of making an entirely soft, squishy thing. Continue reading →

Posted in Human Robots