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#435541 This Giant AI Chip Is the Size of an ...

People say size doesn’t matter, but when it comes to AI the makers of the largest computer chip ever beg to differ. There are plenty of question marks about the gargantuan processor, but its unconventional design could herald an innovative new era in silicon design.

Computer chips specialized to run deep learning algorithms are a booming area of research as hardware limitations begin to slow progress, and both established players and startups are vying to build the successor to the GPU, the specialized graphics chip that has become the workhorse of the AI industry.

On Monday Californian startup Cerebras came out of stealth mode to unveil an AI-focused processor that turns conventional wisdom on its head. For decades chip makers have been focused on making their products ever-smaller, but the Wafer Scale Engine (WSE) is the size of an iPad and features 1.2 trillion transistors, 400,000 cores, and 18 gigabytes of on-chip memory.

The Cerebras Wafer-Scale Engine (WSE) is the largest chip ever built. It measures 46,225 square millimeters and includes 1.2 trillion transistors. Optimized for artificial intelligence compute, the WSE is shown here for comparison alongside the largest graphics processing unit. Image Credit: Used with permission from Cerebras Systems.
There is a method to the madness, though. Currently, getting enough cores to run really large-scale deep learning applications means connecting banks of GPUs together. But shuffling data between these chips is a major drain on speed and energy efficiency because the wires connecting them are relatively slow.

Building all 400,000 cores into the same chip should get round that bottleneck, but there are reasons it’s not been done before, and Cerebras has had to come up with some clever hacks to get around those obstacles.

Regular computer chips are manufactured using a process called photolithography to etch transistors onto the surface of a wafer of silicon. The wafers are inches across, so multiple chips are built onto them at once and then split up afterwards. But at 8.5 inches across, the WSE uses the entire wafer for a single chip.

The problem is that while for standard chip-making processes any imperfections in manufacturing will at most lead to a few processors out of several hundred having to be ditched, for Cerebras it would mean scrapping the entire wafer. To get around this the company built in redundant circuits so that even if there are a few defects, the chip can route around them.

The other big issue with a giant chip is the enormous amount of heat the processors can kick off—so the company has had to design a proprietary water-cooling system. That, along with the fact that no one makes connections and packaging for giant chips, means the WSE won’t be sold as a stand-alone component, but as part of a pre-packaged server incorporating the cooling technology.

There are no details on costs or performance so far, but some customers have already been testing prototypes, and according to Cerebras results have been promising. CEO and co-founder Andrew Feldman told Fortune that early tests show they are reducing training time from months to minutes.

We’ll have to wait until the first systems ship to customers in September to see if those claims stand up. But Feldman told ZDNet that the design of their chip should help spur greater innovation in the way engineers design neural networks. Many cornerstones of this process—for instance, tackling data in batches rather than individual data points—are guided more by the hardware limitations of GPUs than by machine learning theory, but their chip will do away with many of those obstacles.

Whether that turns out to be the case or not, the WSE might be the first indication of an innovative new era in silicon design. When Google announced it’s AI-focused Tensor Processing Unit in 2016 it was a wake-up call for chipmakers that we need some out-of-the-box thinking to square the slowing of Moore’s Law with skyrocketing demand for computing power.

It’s not just tech giants’ AI server farms driving innovation. At the other end of the spectrum, the desire to embed intelligence in everyday objects and mobile devices is pushing demand for AI chips that can run on tiny amounts of power and squeeze into the smallest form factors.

These trends have spawned renewed interest in everything from brain-inspired neuromorphic chips to optical processors, but the WSE also shows that there might be mileage in simply taking a sideways look at some of the other design decisions chipmakers have made in the past rather than just pumping ever more transistors onto a chip.

This gigantic chip might be the first exhibit in a weird and wonderful new menagerie of exotic, AI-inspired silicon.

Image Credit: Used with permission from Cerebras Systems. Continue reading

Posted in Human Robots

#435474 Watch China’s New Hybrid AI Chip Power ...

When I lived in Beijing back in the 90s, a man walking his bike was nothing to look at. But today, I did a serious double-take at a video of a bike walking his man.

No kidding.

The bike itself looks overloaded but otherwise completely normal. Underneath its simplicity, however, is a hybrid computer chip that combines brain-inspired circuits with machine learning processes into a computing behemoth. Thanks to its smart chip, the bike self-balances as it gingerly rolls down a paved track before smoothly gaining speed into a jogging pace while navigating dexterously around obstacles. It can even respond to simple voice commands such as “speed up,” “left,” or “straight.”

Far from a circus trick, the bike is a real-world demo of the AI community’s latest attempt at fashioning specialized hardware to keep up with the challenges of machine learning algorithms. The Tianjic (天机*) chip isn’t just your standard neuromorphic chip. Rather, it has the architecture of a brain-like chip, but can also run deep learning algorithms—a match made in heaven that basically mashes together neuro-inspired hardware and software.

The study shows that China is readily nipping at the heels of Google, Facebook, NVIDIA, and other tech behemoths investing in developing new AI chip designs—hell, with billions in government investment it may have already had a head start. A sweeping AI plan from 2017 looks to catch up with the US on AI technology and application by 2020. By 2030, China’s aiming to be the global leader—and a champion for building general AI that matches humans in intellectual competence.

The country’s ambition is reflected in the team’s parting words.

“Our study is expected to stimulate AGI [artificial general intelligence] development by paving the way to more generalized hardware platforms,” said the authors, led by Dr. Luping Shi at Tsinghua University.

A Hardware Conundrum
Shi’s autonomous bike isn’t the first robotic two-wheeler. Back in 2015, the famed research nonprofit SRI International in Menlo Park, California teamed up with Yamaha to engineer MOTOBOT, a humanoid robot capable of driving a motorcycle. Powered by state-of-the-art robotic hardware and machine learning, MOTOBOT eventually raced MotoGPTM world champion Valentino Rossi in a nail-biting match-off.

However, the technological core of MOTOBOT and Shi’s bike vastly differ, and that difference reflects two pathways towards more powerful AI. One, exemplified by MOTOBOT, is software—developing brain-like algorithms with increasingly efficient architecture, efficacy, and speed. That sounds great, but deep neural nets demand so many computational resources that general-purpose chips can’t keep up.

As Shi told China Science Daily: “CPUs and other chips are driven by miniaturization technologies based on physics. Transistors might shrink to nanoscale-level in 10, 20 years. But what then?” As more transistors are squeezed onto these chips, efficient cooling becomes a limiting factor in computational speed. Tax them too much, and they melt.

For AI processes to continue, we need better hardware. An increasingly popular idea is to build neuromorphic chips, which resemble the brain from the ground up. IBM’s TrueNorth, for example, contains a massively parallel architecture nothing like the traditional Von Neumann structure of classic CPUs and GPUs. Similar to biological brains, TrueNorth’s memory is stored within “synapses” between physical “neurons” etched onto the chip, which dramatically cuts down on energy consumption.

But even these chips are limited. Because computation is tethered to hardware architecture, most chips resemble just one specific type of brain-inspired network called spiking neural networks (SNNs). Without doubt, neuromorphic chips are highly efficient setups with dynamics similar to biological networks. They also don’t play nicely with deep learning and other software-based AI.

Brain-AI Hybrid Core
Shi’s new Tianjic chip brought the two incompatibilities together onto a single piece of brainy hardware.

First was to bridge the deep learning and SNN divide. The two have very different computation philosophies and memory organizations, the team said. The biggest difference, however, is that artificial neural networks transform multidimensional data—image pixels, for example—into a single, continuous, multi-bit 0 and 1 stream. In contrast, neurons in SNNs activate using something called “binary spikes” that code for specific activation events in time.

Confused? Yeah, it’s hard to wrap my head around it too. That’s because SNNs act very similarly to our neural networks and nothing like computers. A particular neuron needs to generate an electrical signal (a “spike”) large enough to transfer down to the next one; little blips in signals don’t count. The way they transmit data also heavily depends on how they’re connected, or the network topology. The takeaway: SNNs work pretty differently than deep learning.

Shi’s team first recreated this firing quirk in the language of computers—0s and 1s—so that the coding mechanism would become compatible with deep learning algorithms. They then carefully aligned the step-by-step building blocks of the two models, which allowed them to tease out similarities into a common ground to further build on. “On the basis of this unified abstraction, we built a cross-paradigm neuron scheme,” they said.

In general, the design allowed both computational approaches to share the synapses, where neurons connect and store data, and the dendrites, the outgoing branches of the neurons. In contrast, the neuron body, where signals integrate, was left reconfigurable for each type of computation, as were the input branches. Each building block was combined into a single unified functional core (FCore), which acts like a deep learning/SNN converter depending on its specific setup. Translation: the chip can do both types of previously incompatible computation.

The Chip
Using nanoscale fabrication, the team arranged 156 FCores, containing roughly 40,000 neurons and 10 million synapses, onto a chip less than a fifth of an inch in length and width. Initial tests showcased the chip’s versatility, in that it can run both SNNs and deep learning algorithms such as the popular convolutional neural network (CNNs) often used in machine vision.

Compared to IBM TrueNorth, the density of Tianjic’s cores increased by 20 percent, speeding up performance ten times and increasing bandwidth at least 100-fold, the team said. When pitted against GPUs, the current hardware darling of machine learning, the chip increased processing throughput up to 100 times, while using just a sliver (1/10,000) of energy.

Although these stats are great, real-life performance is even better as a demo. Here’s where the authors gave their Tianjic brain a body. The team combined one chip with multiple specialized networks to process vision, balance, voice commands, and decision-making in real time. Object detection and target tracking, for example, relied on a deep neural net CNN, whereas voice commands and balance data were recognized using an SNN. The inputs were then integrated inside a neural state machine, which churned out decisions to downstream output modules—for example, controlling the handle bar to turn left.

Thanks to the chip’s brain-like architecture and bilingual ability, Tianjic “allowed all of the neural network models to operate in parallel and realized seamless communication across the models,” the team said. The result is an autonomous bike that rolls after its human, balances across speed bumps, avoids crashing into roadblocks, and answers to voice commands.

General AI?
“It’s a wonderful demonstration and quite impressive,” said the editorial team at Nature, which published the study on its cover last week.

However, they cautioned, when comparing Tianjic with state-of-the-art chips designed for a single problem toe-to-toe on that particular problem, Tianjic falls behind. But building these jack-of-all-trades hybrid chips is definitely worth the effort. Compared to today’s limited AI, what people really want is artificial general intelligence, which will require new architectures that aren’t designed to solve one particular problem.

Until people start to explore, innovate, and play around with different designs, it’s not clear how we can further progress in the pursuit of general AI. A self-driving bike might not be much to look at, but its hybrid brain is a pretty neat place to start.

*The name, in Chinese, means “heavenly machine,” “unknowable mystery of nature,” or “confidentiality.” Go figure.

Image Credit: Alexander Ryabintsev / Shutterstock.com Continue reading

Posted in Human Robots

#435423 Moving Beyond Mind-Controlled Limbs to ...

Brain-machine interface enthusiasts often gush about “closing the loop.” It’s for good reason. On the implant level, it means engineering smarter probes that only activate when they detect faulty electrical signals in brain circuits. Elon Musk’s Neuralink—among other players—are readily pursuing these bi-directional implants that both measure and zap the brain.

But to scientists laboring to restore functionality to paralyzed patients or amputees, “closing the loop” has broader connotations. Building smart mind-controlled robotic limbs isn’t enough; the next frontier is restoring sensation in offline body parts. To truly meld biology with machine, the robotic appendage has to “feel one” with the body.

This month, two studies from Science Robotics describe complementary ways forward. In one, scientists from the University of Utah paired a state-of-the-art robotic arm—the DEKA LUKE—with electrically stimulating remaining nerves above the attachment point. Using artificial zaps to mimic the skin’s natural response patterns to touch, the team dramatically increased the patient’s ability to identify objects. Without much training, he could easily discriminate between the small and large and the soft and hard while blindfolded and wearing headphones.

In another, a team based at the National University of Singapore took inspiration from our largest organ, the skin. Mimicking the neural architecture of biological skin, the engineered “electronic skin” not only senses temperature, pressure, and humidity, but continues to function even when scraped or otherwise damaged. Thanks to artificial nerves that transmit signals far faster than our biological ones, the flexible e-skin shoots electrical data 1,000 times quicker than human nerves.

Together, the studies marry neuroscience and robotics. Representing the latest push towards closing the loop, they show that integrating biological sensibilities with robotic efficiency isn’t impossible (super-human touch, anyone?). But more immediately—and more importantly—they’re beacons of hope for patients who hope to regain their sense of touch.

For one of the participants, a late middle-aged man with speckled white hair who lost his forearm 13 years ago, superpowers, cyborgs, or razzle-dazzle brain implants are the last thing on his mind. After a barrage of emotionally-neutral scientific tests, he grasped his wife’s hand and felt her warmth for the first time in over a decade. His face lit up in a blinding smile.

That’s what scientists are working towards.

Biomimetic Feedback
The human skin is a marvelous thing. Not only does it rapidly detect a multitude of sensations—pressure, temperature, itch, pain, humidity—its wiring “binds” disparate signals together into a sensory fingerprint that helps the brain identify what it’s feeling at any moment. Thanks to over 45 miles of nerves that connect the skin, muscles, and brain, you can pick up a half-full coffee cup, knowing that it’s hot and sloshing, while staring at your computer screen. Unfortunately, this complexity is also why restoring sensation is so hard.

The sensory electrode array implanted in the participant’s arm. Image Credit: George et al., Sci. Robot. 4, eaax2352 (2019)..
However, complex neural patterns can also be a source of inspiration. Previous cyborg arms are often paired with so-called “standard” sensory algorithms to induce a basic sense of touch in the missing limb. Here, electrodes zap residual nerves with intensities proportional to the contact force: the harder the grip, the stronger the electrical feedback. Although seemingly logical, that’s not how our skin works. Every time the skin touches or leaves an object, its nerves shoot strong bursts of activity to the brain; while in full contact, the signal is much lower. The resulting electrical strength curve resembles a “U.”

The LUKE hand. Image Credit: George et al., Sci. Robot. 4, eaax2352 (2019).
The team decided to directly compare standard algorithms with one that better mimics the skin’s natural response. They fitted a volunteer with a robotic LUKE arm and implanted an array of electrodes into his forearm—right above the amputation—to stimulate the remaining nerves. When the team activated different combinations of electrodes, the man reported sensations of vibration, pressure, tapping, or a sort of “tightening” in his missing hand. Some combinations of zaps also made him feel as if he were moving the robotic arm’s joints.

In all, the team was able to carefully map nearly 120 sensations to different locations on the phantom hand, which they then overlapped with contact sensors embedded in the LUKE arm. For example, when the patient touched something with his robotic index finger, the relevant electrodes sent signals that made him feel as if he were brushing something with his own missing index fingertip.

Standard sensory feedback already helped: even with simple electrical stimulation, the man could tell apart size (golf versus lacrosse ball) and texture (foam versus plastic) while blindfolded and wearing noise-canceling headphones. But when the team implemented two types of neuromimetic feedback—electrical zaps that resembled the skin’s natural response—his performance dramatically improved. He was able to identify objects much faster and more accurately under their guidance. Outside the lab, he also found it easier to cook, feed, and dress himself. He could even text on his phone and complete routine chores that were previously too difficult, such as stuffing an insert into a pillowcase, hammering a nail, or eating hard-to-grab foods like eggs and grapes.

The study shows that the brain more readily accepts biologically-inspired electrical patterns, making it a relatively easy—but enormously powerful—upgrade that seamlessly integrates the robotic arms with the host. “The functional and emotional benefits…are likely to be further enhanced with long-term use, and efforts are underway to develop a portable take-home system,” the team said.

E-Skin Revolution: Asynchronous Coded Electronic Skin (ACES)
Flexible electronic skins also aren’t new, but the second team presented an upgrade in both speed and durability while retaining multiplexed sensory capabilities.

Starting from a combination of rubber, plastic, and silicon, the team embedded over 200 sensors onto the e-skin, each capable of discerning contact, pressure, temperature, and humidity. They then looked to the skin’s nervous system for inspiration. Our skin is embedded with a dense array of nerve endings that individually transmit different types of sensations, which are integrated inside hubs called ganglia. Compared to having every single nerve ending directly ping data to the brain, this “gather, process, and transmit” architecture rapidly speeds things up.

The team tapped into this biological architecture. Rather than pairing each sensor with a dedicated receiver, ACES sends all sensory data to a single receiver—an artificial ganglion. This setup lets the e-skin’s wiring work as a whole system, as opposed to individual electrodes. Every sensor transmits its data using a characteristic pulse, which allows it to be uniquely identified by the receiver.

The gains were immediate. First was speed. Normally, sensory data from multiple individual electrodes need to be periodically combined into a map of pressure points. Here, data from thousands of distributed sensors can independently go to a single receiver for further processing, massively increasing efficiency—the new e-skin’s transmission rate is roughly 1,000 times faster than that of human skin.

Second was redundancy. Because data from individual sensors are aggregated, the system still functioned even when any individual receptors are damaged, making it far more resilient than previous attempts. Finally, the setup could easily scale up. Although the team only tested the idea with 240 sensors, theoretically the system should work with up to 10,000.

The team is now exploring ways to combine their invention with other material layers to make it water-resistant and self-repairable. As you might’ve guessed, an immediate application is to give robots something similar to complex touch. A sensory upgrade not only lets robots more easily manipulate tools, doorknobs, and other objects in hectic real-world environments, it could also make it easier for machines to work collaboratively with humans in the future (hey Wall-E, care to pass the salt?).

Dexterous robots aside, the team also envisions engineering better prosthetics. When coated onto cyborg limbs, for example, ACES may give them a better sense of touch that begins to rival the human skin—or perhaps even exceed it.

Regardless, efforts that adapt the functionality of the human nervous system to machines are finally paying off, and more are sure to come. Neuromimetic ideas may very well be the link that finally closes the loop.

Image Credit: Dan Hixson/University of Utah College of Engineering.. Continue reading

Posted in Human Robots

#434685 How Tech Will Let You Learn Anything, ...

Today, over 77 percent of Americans own a smartphone with access to the world’s information and near-limitless learning resources.

Yet nearly 36 million adults in the US are constrained by low literacy skills, excluding them from professional opportunities, prospects of upward mobility, and full engagement with their children’s education.

And beyond its direct impact, low literacy rates affect us all. Improving literacy among adults is predicted to save $230 billion in national healthcare costs and could result in US labor productivity increases of up to 2.5 percent.

Across the board, exponential technologies are making demonetized learning tools, digital training platforms, and literacy solutions more accessible than ever before.

With rising automation and major paradigm shifts underway in the job market, these tools not only promise to make today’s workforce more versatile, but could play an invaluable role in breaking the poverty cycles often associated with low literacy.

Just three years ago, the Barbara Bush Foundation for Family Literacy and the Dollar General Literacy Foundation joined forces to tackle this intractable problem, launching a $7 million Adult Literacy XPRIZE.

Challenging teams to develop smartphone apps that significantly increase literacy skills among adult learners in just 12 months, the competition brought five prize teams to the fore, each targeting multiple demographics across the nation.

Now, after four years of research, prototyping, testing, and evaluation, XPRIZE has just this week announced two grand prize winners: Learning Upgrade and People ForWords.

In this blog, I’ll be exploring the nuts and bolts of our two winning teams and how exponential technologies are beginning to address rapidly shifting workforce demands.

We’ll discuss:

Meeting 100 percent adult literacy rates
Retooling today’s workforce for tomorrow’s job market
Granting the gift of lifelong learning

Let’s dive in.

Adult Literacy XPRIZE
Emphasizing the importance of accessible mediums and scalability, the Adult Literacy XPRIZE called for teams to create mobile solutions that lower the barrier to entry, encourage persistence, develop relevant learning content, and can scale nationally.

Outperforming the competition in two key demographic groups in aggregate—native English speakers and English language learners—teams Learning Upgrade and People ForWords together claimed the prize.

To win, both organizations successfully generated the greatest gains between a pre- and post-test, administered one year apart to learners in a 12-month field test across Los Angeles, Dallas, and Philadelphia.

Prize money in hand, Learning Upgrade and People ForWords are now scaling up their solutions, each targeting a key demographic in America’s pursuit of adult literacy.

Based in San Diego, Learning Upgrade has developed an Android and iOS app that helps students learn English and math through video, songs, and gamification. Offering a total of 21 courses from kindergarten through adult education, Learning Upgrade touts a growing platform of over 900 lessons spanning English, reading, math, and even GED prep.

To further personalize each student’s learning, Learning Upgrade measures time-on-task and builds out formative performance assessments, granting teachers a quantified, real-time view of each student’s progress across both lessons and criteria.

Specialized in English reading skills, Dallas-based People ForWords offers a similarly delocalized model with its mobile game “Codex: Lost Words of Atlantis.” Based on an archaeological adventure storyline, the app features an immersive virtual environment.

Set in the Atlantis Library (now with a 3D rendering underway), Codex takes its students through narrative-peppered lessons covering everything from letter-sound practice to vocabulary reinforcement in a hidden object game.

But while both mobile apps have recruited initial piloting populations, the key to success is scale.

Using a similar incentive prize competition structure to drive recruitment, the second phase of the XPRIZE is a $1 million Barbara Bush Foundation Adult Literacy XPRIZE Communities Competition. For 15 months, the competition will challenge organizations, communities, and individuals alike to onboard adult learners onto both prize-winning platforms and fellow finalist team apps, AmritaCREATE and Cell-Ed.

Each awarded $125,000 for participation in the Communities Competition, AmritaCREATE and Cell-Ed bring yet other nuanced advantages to the table.

While AmritaCREATE curates culturally appropriate e-content relevant to given life skills, Cell-Ed takes a learn-on-the-go approach, offering micro-lessons, on-demand essential skills training, and individualized coaching on any mobile device, no internet required.

Although all these cases target slightly different demographics and problem niches, they converge upon common phenomena: mobility, efficiency, life skill relevance, personalized learning, and practicability.

And what better to scale these benefits than AI and immersive virtual environments?

In the case of education’s growing mobility, 5G and the explosion of connectivity speeds will continue to drive a learn-anytime-anywhere education model, whereby adult users learn on the fly, untethered to web access or rigid time strictures.

As I’ve explored in a previous blog on AI-crowd collaboration, we might also see the rise of AI learning consultants responsible for processing data on how you learn.

Quantifying and analyzing your interaction with course modules, where you get stuck, where you thrive, and what tools cause you ease or frustration, each user’s AI trainer might then issue personalized recommendations based on crowd feedback.

Adding a human touch, each app’s hired teaching consultants would thereby be freed to track many more students’ progress at once, vetting AI-generated tips and adjustments, and offering life coaching along the way.

Lastly, virtual learning environments—and, one day, immersive VR—will facilitate both speed and retention, two of the most critical constraints as learners age.

As I often reference, people generally remember only 10 percent of what we see, 20 percent of what we hear, and 30 percent of what we read…. But over a staggering 90 percent of what we do or experience.

By introducing gamification, immersive testing activities, and visually rich sensory environments, adult literacy platforms have a winning chance at scalability, retention, and user persistence.

Exponential Tools: Training and Retooling a Dynamic Workforce
Beyond literacy, however, virtual and augmented reality have already begun disrupting the professional training market.

As projected by ABI Research, the enterprise VR training market is on track to exceed $6.3 billion in value by 2022.

Leading the charge, Walmart has already implemented VR across 200 Academy training centers, running over 45 modules and simulating everything from unusual customer requests to a Black Friday shopping rush.

Then in September of last year, Walmart committed to a 17,000-headset order of the Oculus Go to equip every US Supercenter, neighborhood market, and discount store with VR-based employee training.

In the engineering world, Bell Helicopter is using VR to massively expedite development and testing of its latest aircraft, FCX-001. Partnering with Sector 5 Digital and HTC VIVE, Bell found it could concentrate a typical six-year aircraft design process into the course of six months, turning physical mockups into CAD-designed virtual replicas.

But beyond the design process itself, Bell is now one of a slew of companies pioneering VR pilot tests and simulations with real-world accuracy. Seated in a true-to-life virtual cockpit, pilots have now tested countless iterations of the FCX-001 in virtual flight, drawing directly onto the 3D model and enacting aircraft modifications in real time.

And in an expansion of our virtual senses, several key players are already working on haptic feedback. In the case of VR flight, French company Go Touch VR is now partnering with software developer FlyInside on fingertip-mounted haptic tech for aviation.

Dramatically reducing time and trouble required for VR-testing pilots, they aim to give touch-based confirmation of every switch and dial activated on virtual flights, just as one would experience in a full-sized cockpit mockup. Replicating texture, stiffness, and even the sensation of holding an object, these piloted devices contain a suite of actuators to simulate everything from a light touch to higher-pressured contact, all controlled by gaze and finger movements.

When it comes to other high-risk simulations, virtual and augmented reality have barely scratched the surface.
Firefighters can now combat virtual wildfires with new platforms like FLAIM Trainer or TargetSolutions. And thanks to the expansion of medical AR/VR services like 3D4Medical or Echopixel, surgeons might soon perform operations on annotated organs and magnified incision sites, speeding up reaction times and vastly improving precision.

But perhaps most urgently, virtual reality will offer an immediate solution to today’s constant industry turnover and large-scale re-education demands.

VR educational facilities with exact replicas of anything from large industrial equipment to minute circuitry will soon give anyone a second chance at the 21st-century job market.

Want to become an electric, autonomous vehicle mechanic at age 44? Throw on a demonetized VR module and learn by doing, testing your prototype iterations at almost zero cost and with no risk of harming others.

Want to be a plasma physicist and play around with a virtual nuclear fusion reactor? Now you’ll be able to simulate results and test out different tweaks, logging Smart Educational Record credits in the process.

As tomorrow’s career model shifts from a “one-and-done graduate degree” to continuous lifelong education, professional VR-based re-education will allow for a continuous education loop, reducing the barrier to entry for anyone wanting to try their hand at a new industry.

Learn Anything, Anytime, at Any Age
As VR and artificial intelligence converge with demonetized mobile connectivity, we are finally witnessing an era in which no one will be left behind.

Whether in pursuit of fundamental life skills, professional training, linguistic competence, or specialized retooling, users of all ages, career paths, income brackets, and goals are now encouraged to be students, no longer condemned to stagnancy.

Traditional constraints need no longer prevent non-native speakers from gaining an equal foothold, or specialists from pivoting into new professions, or low-income parents from staking new career paths.

As exponential technologies drive democratized access, bolstering initiatives such as the Barbara Bush Foundation Adult Literacy XPRIZE are blazing the trail to make education a scalable priority for all.

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Posted in Human Robots

#434658 The Next Data-Driven Healthtech ...

Increasing your healthspan (i.e. making 100 years old the new 60) will depend to a large degree on artificial intelligence. And, as we saw in last week’s blog, healthcare AI systems are extremely data-hungry.

Fortunately, a slew of new sensors and data acquisition methods—including over 122 million wearables shipped in 2018—are bursting onto the scene to meet the massive demand for medical data.

From ubiquitous biosensors, to the mobile healthcare revolution, to the transformative power of the Health Nucleus, converging exponential technologies are fundamentally transforming our approach to healthcare.

In Part 4 of this blog series on Longevity & Vitality, I expand on how we’re acquiring the data to fuel today’s AI healthcare revolution.

In this blog, I’ll explore:

How the Health Nucleus is transforming “sick care” to healthcare
Sensors, wearables, and nanobots
The advent of mobile health

Let’s dive in.

Health Nucleus: Transforming ‘Sick Care’ to Healthcare
Much of today’s healthcare system is actually sick care. Most of us assume that we’re perfectly healthy, with nothing going on inside our bodies, until the day we travel to the hospital writhing in pain only to discover a serious or life-threatening condition.

Chances are that your ailment didn’t materialize that morning; rather, it’s been growing or developing for some time. You simply weren’t aware of it. At that point, once you’re diagnosed as “sick,” our medical system engages to take care of you.

What if, instead of this retrospective and reactive approach, you were constantly monitored, so that you could know the moment anything was out of whack?

Better yet, what if you more closely monitored those aspects of your body that your gene sequence predicted might cause you difficulty? Think: your heart, your kidneys, your breasts. Such a system becomes personalized, predictive, and possibly preventative.

This is the mission of the Health Nucleus platform built by Human Longevity, Inc. (HLI). While not continuous—that will come later, with the next generation of wearable and implantable sensors—the Health Nucleus was designed to ‘digitize’ you once per year to help you determine whether anything is going on inside your body that requires immediate attention.

The Health Nucleus visit provides you with the following tests during a half-day visit:

Whole genome sequencing (30x coverage)
Whole body (non-contrast) MRI
Brain magnetic resonance imaging/angiography (MRI/MRA)
CT (computed tomography) of the heart and lungs
Coronary artery calcium scoring
Electrocardiogram
Echocardiogram
Continuous cardiac monitoring
Clinical laboratory tests and metabolomics

In late 2018, HLI published the results of the first 1,190 clients through the Health Nucleus. The results were eye-opening—especially since these patients were all financially well-off, and already had access to the best doctors.

Following are the physiological and genomic findings in these clients who self-selected to undergo evaluation at HLI’s Health Nucleus.

Physiological Findings [TG]

Two percent had previously unknown tumors detected by MRI
2.5 percent had previously undetected aneurysms detected by MRI
Eight percent had cardiac arrhythmia found on cardiac rhythm monitoring, not previously known
Nine percent had moderate-severe coronary artery disease risk, not previously known
16 percent discovered previously unknown cardiac structure/function abnormalities
30 percent had elevated liver fat, not previously known

Genomic Findings [TG]

24 percent of clients uncovered a rare (unknown) genetic mutation found on WGS
63 percent of clients had a rare genetic mutation with a corresponding phenotypic finding

In summary, HLI’s published results found that 14.4 percent of clients had significant findings that are actionable, requiring immediate or near-term follow-up and intervention.

Long-term value findings were found in 40 percent of the clients we screened. Long-term clinical findings include discoveries that require medical attention or monitoring but are not immediately life-threatening.

The bottom line: most people truly don’t know their actual state of health. The ability to take a fully digital deep dive into your health status at least once per year will enable you to detect disease at stage zero or stage one, when it is most curable.

Sensors, Wearables, and Nanobots
Wearables, connected devices, and quantified self apps will allow us to continuously collect enormous amounts of useful health information.

Wearables like the Quanttus wristband and Vital Connect can transmit your electrocardiogram data, vital signs, posture, and stress levels anywhere on the planet.

In April 2017, we were proud to grant $2.5 million in prize money to the winning team in the Qualcomm Tricorder XPRIZE, Final Frontier Medical Devices.

Using a group of noninvasive sensors that collect data on vital signs, body chemistry, and biological functions, Final Frontier integrates this data in their powerful, AI-based DxtER diagnostic engine for rapid, high-precision assessments.

Their engine combines learnings from clinical emergency medicine and data analysis from actual patients.

Google is developing a full range of internal and external sensors (e.g. smart contact lenses) that can monitor the wearer’s vitals, ranging from blood sugar levels to blood chemistry.

In September 2018, Apple announced its Series 4 Apple Watch, including an FDA-approved mobile, on-the-fly ECG. Granted its first FDA approval, Apple appears to be moving deeper into the sensing healthcare market.

Further, Apple is reportedly now developing sensors that can non-invasively monitor blood sugar levels in real time for diabetic treatment. IoT-connected sensors are also entering the world of prescription drugs.

Last year, the FDA approved the first sensor-embedded pill, Abilify MyCite. This new class of digital pills can now communicate medication data to a user-controlled app, to which doctors may be granted access for remote monitoring.

Perhaps what is most impressive about the next generation of wearables and implantables is the density of sensors, processing, networking, and battery capability that we can now cheaply and compactly integrate.

Take the second-generation OURA ring, for example, which focuses on sleep measurement and management.

The OURA ring looks like a slightly thick wedding band, yet contains an impressive array of sensors and capabilities, including:

Two infrared LED
One infrared sensor
Three temperature sensors
One accelerometer
A six-axis gyro
A curved battery with a seven-day life
The memory, processing, and transmission capability required to connect with your smartphone

Disrupting Medical Imaging Hardware
In 2018, we saw lab breakthroughs that will drive the cost of an ultrasound sensor to below $100, in a packaging smaller than most bandages, powered by a smartphone. Dramatically disrupting ultrasound is just the beginning.

Nanobots and Nanonetworks
While wearables have long been able to track and transmit our steps, heart rate, and other health data, smart nanobots and ingestible sensors will soon be able to monitor countless new parameters and even help diagnose disease.

Some of the most exciting breakthroughs in smart nanotechnology from the past year include:

Researchers from the École Polytechnique Fédérale de Lausanne (EPFL) and the Swiss Federal Institute of Technology in Zurich (ETH Zurich) demonstrated artificial microrobots that can swim and navigate through different fluids, independent of additional sensors, electronics, or power transmission.

Researchers at the University of Chicago proposed specific arrangements of DNA-based molecular logic gates to capture the information contained in the temporal portion of our cells’ communication mechanisms. Accessing the otherwise-lost time-dependent information of these cellular signals is akin to knowing the tune of a song, rather than solely the lyrics.

MIT researchers built micron-scale robots able to sense, record, and store information about their environment. These tiny robots, about 100 micrometers in diameter (approximately the size of a human egg cell), can also carry out pre-programmed computational tasks.

Engineers at University of California, San Diego developed ultrasound-powered nanorobots that swim efficiently through your blood, removing harmful bacteria and the toxins they produce.

But it doesn’t stop there.

As nanosensor and nanonetworking capabilities develop, these tiny bots may soon communicate with each other, enabling the targeted delivery of drugs and autonomous corrective action.

Mobile Health
The OURA ring and the Series 4 Apple Watch are just the tip of the spear when it comes to our future of mobile health. This field, predicted to become a $102 billion market by 2022, puts an on-demand virtual doctor in your back pocket.

Step aside, WebMD.

In true exponential technology fashion, mobile device penetration has increased dramatically, while image recognition error rates and sensor costs have sharply declined.

As a result, AI-powered medical chatbots are flooding the market; diagnostic apps can identify anything from a rash to diabetic retinopathy; and with the advent of global connectivity, mHealth platforms enable real-time health data collection, transmission, and remote diagnosis by medical professionals.

Already available to residents across North London, Babylon Health offers immediate medical advice through AI-powered chatbots and video consultations with doctors via its app.

Babylon now aims to build up its AI for advanced diagnostics and even prescription. Others, like Woebot, take on mental health, using cognitive behavioral therapy in communications over Facebook messenger with patients suffering from depression.

In addition to phone apps and add-ons that test for fertility or autism, the now-FDA-approved Clarius L7 Linear Array Ultrasound Scanner can connect directly to iOS and Android devices and perform wireless ultrasounds at a moment’s notice.

Next, Healthy.io, an Israeli startup, uses your smartphone and computer vision to analyze traditional urine test strips—all you need to do is take a few photos.

With mHealth platforms like ClickMedix, which connects remotely-located patients to medical providers through real-time health data collection and transmission, what’s to stop us from delivering needed treatments through drone delivery or robotic telesurgery?

Welcome to the age of smartphone-as-a-medical-device.

Conclusion
With these DIY data collection and diagnostic tools, we save on transportation costs (time and money), and time bottlenecks.

No longer will you need to wait for your urine or blood results to go through the current information chain: samples will be sent to the lab, analyzed by a technician, results interpreted by your doctor, and only then relayed to you.

Just like the “sage-on-the-stage” issue with today’s education system, healthcare has a “doctor-on-the-dais” problem. Current medical procedures are too complicated and expensive for a layperson to perform and analyze on their own.

The coming abundance of healthcare data promises to transform how we approach healthcare, putting the power of exponential technologies in the patient’s hands and revolutionizing how we live.

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