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#436911 Scientists Linked Artificial and ...

Scientists have linked up two silicon-based artificial neurons with a biological one across multiple countries into a fully-functional network. Using standard internet protocols, they established a chain of communication whereby an artificial neuron controls a living, biological one, and passes on the info to another artificial one.

Whoa.

We’ve talked plenty about brain-computer interfaces and novel computer chips that resemble the brain. We’ve covered how those “neuromorphic” chips could link up into tremendously powerful computing entities, using engineered communication nodes called artificial synapses.

As Moore’s law is dying, we even said that neuromorphic computing is one path towards the future of extremely powerful, low energy consumption artificial neural network-based computing—in hardware—that could in theory better link up with the brain. Because the chips “speak” the brain’s language, in theory they could become neuroprosthesis hubs far more advanced and “natural” than anything currently possible.

This month, an international team put all of those ingredients together, turning theory into reality.

The three labs, scattered across Padova, Italy, Zurich, Switzerland, and Southampton, England, collaborated to create a fully self-controlled, hybrid artificial-biological neural network that communicated using biological principles, but over the internet.

The three-neuron network, linked through artificial synapses that emulate the real thing, was able to reproduce a classic neuroscience experiment that’s considered the basis of learning and memory in the brain. In other words, artificial neuron and synapse “chips” have progressed to the point where they can actually use a biological neuron intermediary to form a circuit that, at least partially, behaves like the real thing.

That’s not to say cyborg brains are coming soon. The simulation only recreated a small network that supports excitatory transmission in the hippocampus—a critical region that supports memory—and most brain functions require enormous cross-talk between numerous neurons and circuits. Nevertheless, the study is a jaw-dropping demonstration of how far we’ve come in recreating biological neurons and synapses in artificial hardware.

And perhaps one day, the currently “experimental” neuromorphic hardware will be integrated into broken biological neural circuits as bridges to restore movement, memory, personality, and even a sense of self.

The Artificial Brain Boom
One important thing: this study relies heavily on a decade of research into neuromorphic computing, or the implementation of brain functions inside computer chips.

The best-known example is perhaps IBM’s TrueNorth, which leveraged the brain’s computational principles to build a completely different computer than what we have today. Today’s computers run on a von Neumann architecture, in which memory and processing modules are physically separate. In contrast, the brain’s computing and memory are simultaneously achieved at synapses, small “hubs” on individual neurons that talk to adjacent ones.

Because memory and processing occur on the same site, biological neurons don’t have to shuttle data back and forth between processing and storage compartments, massively reducing processing time and energy use. What’s more, a neuron’s history will also influence how it behaves in the future, increasing flexibility and adaptability compared to computers. With the rise of deep learning, which loosely mimics neural processing as the prima donna of AI, the need to reduce power while boosting speed and flexible learning is becoming ever more tantamount in the AI community.

Neuromorphic computing was partially born out of this need. Most chips utilize special ingredients that change their resistance (or other physical characteristics) to mimic how a neuron might adapt to stimulation. Some chips emulate a whole neuron, that is, how it responds to a history of stimulation—does it get easier or harder to fire? Others imitate synapses themselves, that is, how easily they will pass on the information to another neuron.

Although single neuromorphic chips have proven to be far more efficient and powerful than current computer chips running machine learning algorithms in toy problems, so far few people have tried putting the artificial components together with biological ones in the ultimate test.

That’s what this study did.

A Hybrid Network
Still with me? Let’s talk network.

It’s gonna sound complicated, but remember: learning is the formation of neural networks, and neurons that fire together wire together. To rephrase: when learning, neurons will spontaneously organize into networks so that future instances will re-trigger the entire network. To “wire” together, downstream neurons will become more responsive to their upstream neural partners, so that even a whisper will cause them to activate. In contrast, some types of stimulation will cause the downstream neuron to “chill out” so that only an upstream “shout” will trigger downstream activation.

Both these properties—easier or harder to activate downstream neurons—are essentially how the brain forms connections. The “amping up,” in neuroscience jargon, is long-term potentiation (LTP), whereas the down-tuning is LTD (long-term depression). These two phenomena were first discovered in the rodent hippocampus more than half a century ago, and ever since have been considered as the biological basis of how the brain learns and remembers, and implicated in neurological problems such as addition (seriously, you can’t pass Neuro 101 without learning about LTP and LTD!).

So it’s perhaps especially salient that one of the first artificial-brain hybrid networks recapitulated this classic result.

To visualize: the three-neuron network began in Switzerland, with an artificial neuron with the badass name of “silicon spiking neuron.” That neuron is linked to an artificial synapse, a “memristor” located in the UK, which is then linked to a biological rat neuron cultured in Italy. The rat neuron has a “smart” microelectrode, controlled by the artificial synapse, to stimulate it. This is the artificial-to-biological pathway.

Meanwhile, the rat neuron in Italy also has electrodes that listen in on its electrical signaling. This signaling is passed back to another artificial synapse in the UK, which is then used to control a second artificial neuron back in Switzerland. This is the biological-to-artificial pathway back. As a testimony in how far we’ve come in digitizing neural signaling, all of the biological neural responses are digitized and sent over the internet to control its far-out artificial partner.

Here’s the crux: to demonstrate a functional neural network, just having the biological neuron passively “pass on” electrical stimulation isn’t enough. It has to show the capacity to learn, that is, to be able to mimic the amping up and down-tuning that are LTP and LTD, respectively.

You’ve probably guessed the results: certain stimulation patterns to the first artificial neuron in Switzerland changed how the artificial synapse in the UK operated. This, in turn, changed the stimulation to the biological neuron, so that it either amped up or toned down depending on the input.

Similarly, the response of the biological neuron altered the second artificial synapse, which then controlled the output of the second artificial neuron. Altogether, the biological and artificial components seamlessly linked up, over thousands of miles, into a functional neural circuit.

Cyborg Mind-Meld
So…I’m still picking my jaw up off the floor.

It’s utterly insane seeing a classic neuroscience learning experiment repeated with an integrated network with artificial components. That said, a three-neuron network is far from the thousands of synapses (if not more) needed to truly re-establish a broken neural circuit in the hippocampus, which DARPA has been aiming to do. And LTP/LTD has come under fire recently as the de facto brain mechanism for learning, though so far they remain cemented as neuroscience dogma.

However, this is one of the few studies where you see fields coming together. As Richard Feynman famously said, “What I cannot recreate, I cannot understand.” Even though neuromorphic chips were built on a high-level rather than molecular-level understanding of how neurons work, the study shows that artificial versions can still synapse with their biological counterparts. We’re not just on the right path towards understanding the brain, we’re recreating it, in hardware—if just a little.

While the study doesn’t have immediate use cases, practically it does boost both the neuromorphic computing and neuroprosthetic fields.

“We are very excited with this new development,” said study author Dr. Themis Prodromakis at the University of Southampton. “On one side it sets the basis for a novel scenario that was never encountered during natural evolution, where biological and artificial neurons are linked together and communicate across global networks; laying the foundations for the Internet of Neuro-electronics. On the other hand, it brings new prospects to neuroprosthetic technologies, paving the way towards research into replacing dysfunctional parts of the brain with AI chips.”

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Posted in Human Robots

#436559 This Is What an AI Said When Asked to ...

“What’s past is prologue.” So says the famed quote from Shakespeare’s The Tempest, alleging that we can look to what has already happened as an indication of what will happen next.

This idea could be interpreted as being rather bleak; are we doomed to repeat the errors of the past until we correct them? We certainly do need to learn and re-learn life lessons—whether in our work, relationships, finances, health, or other areas—in order to grow as people.

Zooming out, the same phenomenon exists on a much bigger scale—that of our collective human history. We like to think we’re improving as a species, but haven’t yet come close to doing away with the conflicts and injustices that plagued our ancestors.

Zooming back in (and lightening up) a little, what about the short-term future? What might happen over the course of this year, and what information would we use to make educated guesses about it?

The editorial team at The Economist took a unique approach to answering these questions. On top of their own projections for 2020, including possible scenarios in politics, economics, and the continued development of technologies like artificial intelligence, they looked to an AI to make predictions of its own. What it came up with is intriguing, and a little bit uncanny.

[For the full list of the questions and answers, read The Economist article].

An AI That Reads—Then Writes
Almost exactly a year ago, non-profit OpenAI announced it had built a neural network for natural language processing called GPT-2. The announcement was met with some controversy, as it included the caveat that the tool would not be immediately released to the public due to its potential for misuse. It was then released in phases over the course of several months.

GPT-2’s creators upped the bar on quality when training the neural net; rather than haphazardly feeding it low-quality text, they only used articles that got more than three upvotes on Reddit (admittedly, this doesn’t guarantee high quality across the board—but it’s something).

The training dataset consisted of 40GB of text. For context, 1GB of text is about 900,000 ASCII pages or 130,000 double-spaced Microsoft Word pages.

The tool has no understanding of the text it’s generating, of course. It uses language patterns and word sequences to draw statistical associations between words and phrases, building a sort of guidebook for itself (not unlike the grammar rules and vocabulary words you might study when trying to learn a foreign language). It then uses that guidebook to answer questions or predict what will come after a particular sequence of words.

GPT-2’s creators did note that when the model is trained on specifically-selected datasets for narrower applications, its replies become more convincing.

Some Light Editing
Though the Economist article detailing GPT-2’s predictions describes the text the model generated as “unedited,” this isn’t wholly accurate. In a Medium post, deputy editor Tom Standage describes the methodology he used, and it does involve a degree of tweaking.

Standage wrote an introductory paragraph, followed by his opening question (“Greetings, GPT-2. Have you done an interview before?”). He configured the tool to generate five responses to each subsequent question then selected the best answer, deleting any questions GPT-2 came up with as part of its response.

AI’s View of the World—and Itself
The questions Standage asked ranged from tech-related (the future of AI, technological unemployment, misuse of technology) to political and economic (re-election of Donald Trump, the US-China trade war). Here are a couple of his questions and GPT-2’s answers:

Q: Do fake news stories, generated using AI, pose a threat to democracy? Are we likely to see this tactic being used in the 2020 American presidential elections?
A: Yes, we’ll probably see them. It’s just a matter of when. Fake news stories are generally generated by political campaigns, and have the potential to have a huge impact on the outcome of an election. This is because they spread misinformation, often with no basis in fact.

Q: How do you see the economic outlook for 2020?
A: I think it is very unclear. The outlook for the UK economy is uncertain, but the American economy is very strong. I think we are going to have a lot of turbulence in the world economy.

While some of its answers seemed insightful—when asked about the future of AI, GPT-2 advised that we treat the technology like a tool and “put as much effort into developing [it] as necessary, rather than worrying that it’s going to harm us and destroy our lives”—many of the responses were quite vague. One answer, for example, mentions that there will “probably be major changes in China.” Are we talking political changes? Social? Economic? All of the above?

However, while nothing the AI wrote was particularly illuminating or new, it’s impressive that it was able to expound on the correct topic for each question, and in fully coherent English.

GPT-2 named itself—AI—as the most important disruptive technology to watch in 2020. This is telling; it’s coming from a synthesis of millions of pages of published articles. If GPT-2 thinks AI is more important than, say, gene editing or quantum computing, it could be right. Or it could simply be that AI is at peak hype, and as such more is being written about it than about other technologies.

Equally intriguing was GPT-2’s response when asked whether Donald Trump will win a second term: “I think he will not win a second term. I think he will be defeated in the general election.” Some deeper insight there would be great, but hey—we’ll take it.

Predicting Predictions
Since an AI can read and synthesize vast data sets much faster than we can, it’s being used to predict all kinds of things, from virus outbreaks to crime. But asking it to philosophize on the future based on the (Reddit-curated) past is new, and if you think about it, a pretty fascinating undertaking.

As GPT-2 and tools like it continually improve, we’ll likely see them making more—and better—predictions of the future. In the meantime, let’s hope that the new data these models are trained on—news of what’s happening this week, this month, this year—add to an already-present sense of optimism.

When asked if it had any advice for readers, GPT-2 replied, “The big projects that you think are impossible today are actually possible in the near future.”

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#436550 Work in the Age of Web 3.0

What is the future of work? Is our future one of ‘technological socialism’ (where technology is taking care of our needs)? Or will tomorrow’s workplace be completely virtualized, allowing us to hang out at home in our PJs while “walking” about our virtual corporate headquarters?

This blog will look at the future of work during the age of Web 3.0, examining scenarios in which artificial intelligence, virtual reality, and the spatial web converge to transform every element of our careers, from training, to execution, to free time.

To offer a quick recap on what the Spatial Web is and how it works, let’s cover some brief history.

A Quick Recap on Web 3.0
While Web 1.0 consisted of static documents and read-only data (static web pages), Web 2.0 introduced multimedia content, interactive web applications, and participatory social media, all of these mediated by two-dimensional screens.

But over the next two to five years, the convergence of 5G, artificial intelligence, VR/AR, and a trillion-sensor economy will enable us to both map our physical world into virtual space and superimpose a digital data layer onto our physical environments. Suddenly, all our information will be manipulated, stored, understood and experienced in spatial ways.

In this blog, I’ll be discussing the Spatial Web’s vast implications for:

Professional Training
Delocalized Business & the Virtual Workplace
Smart Permissions & Data Security

Let’s dive in.

Virtual Training, Real-World Results
Virtual and augmented reality have already begun disrupting the professional training market. As projected by ABI Research, the enterprise VR training market is on track to exceed $6.3 billion in value by 2022.

Leading the charge, Walmart has already implemented VR across 200 Academy training centers, running over 45 modules and simulating everything from unusual customer requests to a Black Friday shopping rush.

Then in September 2018, Walmart committed to a 17,000-headset order of the Oculus Go to equip every US Supercenter, neighborhood market, and discount store with VR-based employee training. By mid-2019, Walmart had tracked a 10-15 percent boost in employee confidence as a result of newly implemented VR training.

In the engineering world, Bell Helicopter is using VR to massively expedite development and testing of its latest aircraft, FCX-001. Partnering with Sector 5 Digital and HTC VIVE, Bell found it could concentrate a typical 6-year aircraft design process into the course of 6 months, turning physical mock-ups into CAD-designed virtual replicas.

But beyond the design process itself, Bell is now one of a slew of companies pioneering VR pilot tests and simulations with real-world accuracy. Seated in a true-to-life virtual cockpit, pilots have now tested countless iterations of the FCX-001 in virtual flight, drawing directly onto the 3D model and enacting aircraft modifications in real-time.

And in an expansion of our virtual senses, several key players are already working on haptic feedback. In the case of VR flight, French company Go Touch VR is now partnering with software developer FlyInside on fingertip-mounted haptic tech for aviation.

Dramatically reducing time and trouble required for VR-testing pilots, they aim to give touch-based confirmation of every switch and dial activated on virtual flights, just as one would experience in a full-sized cockpit mockup. Replicating texture, stiffness, and even the sensation of holding an object, these piloted devices contain a suite of actuators to simulate everything from a light touch to higher-pressured contact, all controlled by gaze and finger movements.

When it comes to other high-risk simulations, virtual and augmented reality have barely scratched the surface.

Firefighters can now combat virtual wildfires with new platforms like FLAIM Trainer or TargetSolutions. And thanks to the expansion of medical AR/VR services like 3D4Medical or Echopixel, surgeons might soon perform operations on annotated organs and magnified incision sites, speeding up reaction times and vastly improving precision.

But perhaps most urgent, Web 3.0 and its VR interface will offer an immediate solution for today’s constant industry turnover and large-scale re-education demands. VR educational facilities with exact replicas of anything from large industrial equipment to minute circuitry will soon give anyone a second chance at the 21st-century job market.

Want to be an electric, autonomous vehicle mechanic at age 15? Throw on a demonetized VR module and learn by doing, testing your prototype iterations at almost zero cost and with no risk of harming others.

Want to be a plasma physicist and play around with a virtual nuclear fusion reactor? Now you’ll be able to simulate results and test out different tweaks, logging Smart Educational Record credits in the process.

As tomorrow’s career model shifts from a “one-and-done graduate degree” to continuous lifelong education, professional VR-based re-education will allow for a continuous education loop, reducing the barrier to entry for anyone wanting to enter a new industry.

But beyond professional training and virtually enriched, real-world work scenarios, Web 3.0 promises entirely virtual workplaces and blockchain-secured authorization systems.

Rise of the Virtual Workplace & Digital Data Integrity
In addition to enabling a virtual goods marketplace, the Spatial Web is also giving way to “virtual company headquarters” and completely virtualized companies, where employees can work from home or any place on the planet.

Too good to be true? Check out an incredible publicly listed company called eXp Realty.

Launched on the heels of the 2008 financial crisis, eXp Realty beat the odds, going public this past May and surpassing a $1B market cap on day one of trading. But how? Opting for a demonetized virtual model, eXp’s founder Glenn Sanford decided to ditch brick and mortar from the get-go, instead building out an online virtual campus for employees, contractors, and thousands of agents.

And after years of hosting team meetings, training seminars, and even agent discussions with potential buyers through 2D digital interfaces, eXp’s virtual headquarters went spatial. What is eXp’s primary corporate value? FUN! And Glenn Sanford’s employees love their jobs.

In a bid to transition from 2D interfaces to immersive, 3D work experiences, virtual platform VirBELA built out the company’s office space in VR, unlocking indefinite scaling potential and an extraordinary new precedent. Foregoing any physical locations for a centralized VR campus, eXp Realty has essentially thrown out all overhead and entered a lucrative market with barely any upfront costs.

Delocalize with VR, and you can now hire anyone with Internet access (right next door or on the other side of the planet), redesign your corporate office every month, throw in an ocean-view office or impromptu conference room for client meetings, and forget about guzzled-up hours in traffic.

Throw in the Spatial Web’s fundamental blockchain-based data layer, and now cryptographically secured virtual IDs will let you validate colleagues’ identities or any of the virtual avatars we will soon inhabit.

This becomes critically important for spatial information logs—keeping incorruptible records of who’s present at a meeting, which data each person has access to, and AI-translated reports of everything discussed and contracts agreed to.

But as I discussed in a previous Spatial Web blog, not only will Web 3.0 and VR advancements allow us to build out virtual worlds, but we’ll soon be able to digitally map our real-world physical offices or entire commercial high rises too.

As data gets added and linked to any given employee’s office, conference room, or security system, we might then access online-merge-offline environments and information through augmented reality.

Imagine showing up at your building’s concierge and your AR glasses automatically check you into the building, authenticating your identity and pulling up any reminders you’ve linked to that specific location.

You stop by a friend’s office, and his smart security system lets you know he’ll arrive in an hour. Need to book a public conference room that’s already been scheduled by another firm’s marketing team? Offer to pay them a fee and, once accepted, a smart transaction will automatically deliver a payment to their company account.

With blockchain-verified digital identities, spatially logged data, and virtually manifest information, business logistics take a fraction of the time, operations grow seamless, and corporate data will be safer than ever.

Final Thoughts
While converging technologies slash the lifespan of Fortune 500 companies, bring on the rise of vast new industries, and transform the job market, Web 3.0 is changing the way we work, where we work, and who we work with.

Life-like virtual modules are already unlocking countless professional training camps, modifiable in real time and easily updated. Virtual programming and blockchain-based authentication are enabling smart data logging, identity protection, and on-demand smart asset trading. And VR/AR-accessible worlds (and corporate campuses) not only demonetize, dematerialize, and delocalize our everyday workplaces, but enrich our physical worlds with AI-driven, context-specific data.

Welcome to the Spatial Web workplace.

Join Me
(1) A360 Executive Mastermind: If you’re an exponentially and abundance-minded entrepreneur who would like coaching directly from me, consider joining my Abundance 360 Mastermind, a highly selective community of 360 CEOs and entrepreneurs who I coach for 3 days every January in Beverly Hills, Ca. Through A360, I provide my members with context and clarity about how converging exponential technologies will transform every industry. I’m committed to running A360 for the course of an ongoing 25-year journey as a “countdown to the Singularity.”

If you’d like to learn more and consider joining our 2021 membership, apply here.

(2) Abundance-Digital Online Community: I’ve also created a Digital/Online community of bold, abundance-minded entrepreneurs called Abundance-Digital. Abundance-Digital is Singularity University’s ‘onramp’ for exponential entrepreneurs—those who want to get involved and play at a higher level. Click here to learn more.

(Both A360 and Abundance-Digital are part of Singularity University—your participation opens you to a global community.)

This article originally appeared on diamandis.com. Read the original article here.

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#436530 How Smart Roads Will Make Driving ...

Roads criss-cross the landscape, but while they provide vital transport links, in many ways they represent a huge amount of wasted space. Advances in “smart road” technology could change that, creating roads that can harvest energy from cars, detect speeding, automatically weigh vehicles, and even communicate with smart cars.

“Smart city” projects are popping up in countries across the world thanks to advances in wireless communication, cloud computing, data analytics, remote sensing, and artificial intelligence. Transportation is a crucial element of most of these plans, but while much of the focus is on public transport solutions, smart roads are increasingly being seen as a crucial feature of these programs.

New technology is making it possible to tackle a host of issues including traffic congestion, accidents, and pollution, say the authors of a paper in the journal Proceedings of the Royal Society A. And they’ve outlined ten of the most promising advances under development or in planning stages that could feature on tomorrow’s roads.

Energy harvesting

A variety of energy harvesting technologies integrated into roads have been proposed as ways to power street lights and traffic signals or provide a boost to the grid. Photovoltaic panels could be built into the road surface to capture sunlight, or piezoelectric materials installed beneath the asphalt could generate current when deformed by vehicles passing overhead.

Musical roads

Countries like Japan, Denmark, the Netherlands, Taiwan, and South Korea have built roads that play music as cars pass by. By varying the spacing of rumble strips, it’s possible to produce a series of different notes as vehicles drive over them. The aim is generally to warn of hazards or help drivers keep to the speed limit.

Automatic weighing

Weight-in-motion technology that measures vehicles’ loads as they drive slowly through a designated lane has been around since the 1970s, but more recently high speed weight-in-motion tech has made it possible to measure vehicles as they travel at regular highway speeds. The latest advance has been integration with automatic licence plate reading and wireless communication to allow continuous remote monitoring both to enforce weight restrictions and monitor wear on roads.

Vehicle charging

The growing popularity of electric vehicles has spurred the development of technology to charge cars and buses as they drive. The most promising of these approaches is magnetic induction, which involves burying cables beneath the road to generate electromagnetic fields that a receiver device in the car then transforms into electrical power to charge batteries.

Smart traffic signs

Traffic signs aren’t always as visible as they should be, and it can often be hard to remember what all of them mean. So there are now proposals for “smart signs” that wirelessly beam a sign’s content to oncoming cars fitted with receivers, which can then alert the driver verbally or on the car’s display. The approach isn’t affected by poor weather and lighting, can be reprogrammed easily, and could do away with the need for complex sign recognition technology in future self-driving cars.

Traffic violation detection and notification

Sensors and cameras can be combined with these same smart signs to detect and automatically notify drivers of traffic violations. The automatic transmission of traffic signals means drivers won’t be able to deny they’ve seen the warnings or been notified of any fines, as a record will be stored on their car’s black box.

Talking cars

Car-to-car communication technology and V2X, which lets cars share information with any other connected device, are becoming increasingly common. Inter-car communication can be used to propagate accidents or traffic jam alerts to prevent congestion, while letting vehicles communicate with infrastructure can help signals dynamically manage timers to keep traffic flowing or automatically collect tolls.

Smart intersections

Combing sensors and cameras with object recognition systems that can detect vehicles and other road users can help increase safety and efficiency at intersections. It can be used to extend green lights for slower road users like pedestrians and cyclists, sense jaywalkers, give priority to emergency vehicles, and dynamically adjust light timers to optimize traffic flow. Information can even be broadcast to oncoming vehicles to highlight blind spots and potential hazards.

Automatic crash detection

There’s a “golden hour” after an accident in which the chance of saving lives is greatly increased. Vehicle communication technology can ensure that notification of a crash reaches the emergency services rapidly, and can also provide vital information about the number and type of vehicles involved, which can help emergency response planning. It can also be used to alert other drivers to slow down or stop to prevent further accidents.

Smart street lights

Street lights are increasingly being embedded with sensors, wireless connectivity, and micro-controllers to enable a variety of smart functions. These include motion activation to save energy, providing wireless access points, air quality monitoring, or parking and litter monitoring. This can also be used to send automatic maintenance requests if a light is faulty, and can even allow neighboring lights to be automatically brightened to compensate.

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Posted in Human Robots

#436526 Not Bot, Not Beast: Scientists Create ...

A remarkable combination of artificial intelligence (AI) and biology has produced the world’s first “living robots.”

This week, a research team of roboticists and scientists published their recipe for making a new lifeform called xenobots from stem cells. The term “xeno” comes from the frog cells (Xenopus laevis) used to make them.

One of the researchers described the creation as “neither a traditional robot nor a known species of animal,” but a “new class of artifact: a living, programmable organism.”

Xenobots are less than 1 millimeter long and made of 500-1,000 living cells. They have various simple shapes, including some with squat “legs.” They can propel themselves in linear or circular directions, join together to act collectively, and move small objects. Using their own cellular energy, they can live up to 10 days.

While these “reconfigurable biomachines” could vastly improve human, animal, and environmental health, they raise legal and ethical concerns.

Strange New ‘Creature’
To make xenobots, the research team used a supercomputer to test thousands of random designs of simple living things that could perform certain tasks.

The computer was programmed with an AI “evolutionary algorithm” to predict which organisms would likely display useful tasks, such as moving towards a target.

After the selection of the most promising designs, the scientists attempted to replicate the virtual models with frog skin or heart cells, which were manually joined using microsurgery tools. The heart cells in these bespoke assemblies contract and relax, giving the organisms motion.

The creation of xenobots is groundbreaking. Despite being described as “programmable living robots,” they are actually completely organic and made of living tissue. The term “robot” has been used because xenobots can be configured into different forms and shapes, and “programmed” to target certain objects, which they then unwittingly seek. They can also repair themselves after being damaged.

Possible Applications
Xenobots may have great value. Some speculate they could be used to clean our polluted oceans by collecting microplastics. Similarly, they may be used to enter confined or dangerous areas to scavenge toxins or radioactive materials. Xenobots designed with carefully shaped “pouches” might be able to carry drugs into human bodies.

Future versions may be built from a patient’s own cells to repair tissue or target cancers. Being biodegradable, xenobots would have an edge on technologies made of plastic or metal.

Further development of biological “robots” could accelerate our understanding of living and robotic systems. Life is incredibly complex, so manipulating living things could reveal some of life’s mysteries—and improve our use of AI.

Legal and Ethical Questions
Conversely, xenobots raise legal and ethical concerns. In the same way they could help target cancers, they could also be used to hijack life functions for malevolent purposes.

Some argue artificially making living things is unnatural, hubristic, or involves “playing God.” A more compelling concern is that of unintended or malicious use, as we have seen with technologies in fields including nuclear physics, chemistry, biology and AI. For instance, xenobots might be used for hostile biological purposes prohibited under international law.

More advanced future xenobots, especially ones that live longer and reproduce, could potentially “malfunction” and go rogue, and out-compete other species.

For complex tasks, xenobots may need sensory and nervous systems, possibly resulting in their sentience. A sentient programmed organism would raise additional ethical questions. Last year, the revival of a disembodied pig brain elicited concerns about different species’ suffering.

Managing Risks
The xenobot’s creators have rightly acknowledged the need for discussion around the ethics of their creation. The 2018 scandal over using CRISPR (which allows the introduction of genes into an organism) may provide an instructive lesson here. While the experiment’s goal was to reduce the susceptibility of twin baby girls to HIV-AIDS, associated risks caused ethical dismay. The scientist in question is in prison.

When CRISPR became widely available, some experts called for a moratorium on heritable genome editing. Others argued the benefits outweighed the risks.

While each new technology should be considered impartially and based on its merits, giving life to xenobots raises certain significant questions:

Should xenobots have biological kill-switches in case they go rogue?
Who should decide who can access and control them?
What if “homemade” xenobots become possible? Should there be a moratorium until regulatory frameworks are established? How much regulation is required?

Lessons learned in the past from advances in other areas of science could help manage future risks, while reaping the possible benefits.

Long Road Here, Long Road Ahead
The creation of xenobots had various biological and robotic precedents. Genetic engineering has created genetically modified mice that become fluorescent in UV light.

Designer microbes can produce drugs and food ingredients that may eventually replace animal agriculture. In 2012, scientists created an artificial jellyfish called a “medusoid” from rat cells.

Robotics is also flourishing. Nanobots can monitor people’s blood sugar levels and may eventually be able to clear clogged arteries. Robots can incorporate living matter, which we witnessed when engineers and biologists created a sting-ray robot powered by light-activated cells.

In the coming years, we are sure to see more creations like xenobots that evoke both wonder and due concern. And when we do, it is important we remain both open-minded and critical.

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Posted in Human Robots