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#439042 How Scientists Used Ultrasound to Read ...
Thanks to neural implants, mind reading is no longer science fiction.
As I’m writing this sentence, a tiny chip with arrays of electrodes could sit on my brain, listening in on the crackling of my neurons firing as my hands dance across the keyboard. Sophisticated algorithms could then decode these electrical signals in real time. My brain’s inner language to plan and move my fingers could then be used to guide a robotic hand to do the same. Mind-to-machine control, voilà!
Yet as the name implies, even the most advanced neural implant has a problem: it’s an implant. For electrodes to reliably read the brain’s electrical chatter, they need to pierce through the its protective membrane and into brain tissue. Danger of infection aside, over time, damage accumulates around the electrodes, distorting their signals or even rendering them unusable.
Now, researchers from Caltech have paved a way to read the brain without any physical contact. Key to their device is a relatively new superstar in neuroscience: functional ultrasound, which uses sound waves to capture activity in the brain.
In monkeys, the technology could reliably predict their eye movement and hand gestures after just a single trial—without the usual lengthy training process needed to decode a movement. If adopted by humans, the new mind-reading tech represents a triple triumph: it requires minimal surgery and minimal learning, but yields maximal resolution for brain decoding. For people who are paralyzed, it could be a paradigm shift in how they control their prosthetics.
“We pushed the limits of ultrasound neuroimaging and were thrilled that it could predict movement,” said study author Dr. Sumner Norman.
To Dr. Krishna Shenoy at Stanford, who was not involved, the study will finally put ultrasound “on the map as a brain-machine interface technique. Adding to this toolkit is spectacular,” he said.
Breaking the Sound Barrier
Using sound to decode brain activity might seem preposterous, but ultrasound has had quite the run in medicine. You’ve probably heard of its most common use: taking photos of a fetus in pregnancy. The technique uses a transducer, which emits ultrasound pulses into the body and finds boundaries in tissue structure by analyzing the sound waves that bounce back.
Roughly a decade ago, neuroscientists realized they could adapt the tech for brain scanning. Rather than directly measuring the brain’s electrical chatter, it looks at a proxy—blood flow. When certain brain regions or circuits are active, the brain requires much more energy, which is provided by increased blood flow. In this way, functional ultrasound works similarly to functional MRI, but at a far higher resolution—roughly ten times, the authors said. Plus, people don’t have to lie very still in an expensive, claustrophobic magnet.
“A key question in this work was: If we have a technique like functional ultrasound that gives us high-resolution images of the brain’s blood flow dynamics in space and over time, is there enough information from that imaging to decode something useful about behavior?” said study author Dr. Mikhail Shapiro.
There’s plenty of reasons for doubt. As the new kid on the block, functional ultrasound has some known drawbacks. A major one: it gives a far less direct signal than electrodes. Previous studies show that, with multiple measurements, it can provide a rough picture of brain activity. But is that enough detail to guide a robotic prosthesis?
One-Trial Wonder
The new study put functional ultrasound to the ultimate test: could it reliably detect movement intention in monkeys? Because their brains are the most similar to ours, rhesus macaque monkeys are often the critical step before a brain-machine interface technology is adapted for humans.
The team first inserted small ultrasound transducers into the skulls of two rhesus monkeys. While it sounds intense, the surgery doesn’t penetrate the brain or its protective membrane; it’s only on the skull. Compared to electrodes, this means the brain itself isn’t physically harmed.
The device is linked to a computer, which controls the direction of sound waves and captures signals from the brain. For this study, the team aimed the pulses at the posterior parietal cortex, a part of the “motor” aspect of the brain, which plans movement. If right now you’re thinking about scrolling down this page, that’s the brain region already activated, before your fingers actually perform the movement.
Then came the tests. The first looked at eye movements—something pretty necessary before planning actual body movements without tripping all over the place. Here, the monkeys learned to focus on a central dot on a computer screen. A second dot, either left or right, then flashed. The monkeys’ task was to flicker their eyes to the most recent dot. It’s something that seems easy for us, but requires sophisticated brain computation.
The second task was more straightforward. Rather than just moving their eyes to the second target dot, the monkeys learned to grab and manipulate a joystick to move a cursor to that target.
Using brain imaging to decode the mind and control movement. Image Credit: S. Norman, Caltech
As the monkeys learned, so did the device. Ultrasound data capturing brain activity was fed into a sophisticated machine learning algorithm to guess the monkeys’ intentions. Here’s the kicker: once trained, using data from just a single trial, the algorithm was able to correctly predict the monkeys’ actual eye movement—whether left or right—with roughly 78 percent accuracy. The accuracy for correctly maneuvering the joystick was even higher, at nearly 90 percent.
That’s crazy accurate, and very much needed for a mind-controlled prosthetic. If you’re using a mind-controlled cursor or limb, the last thing you’d want is to have to imagine the movement multiple times before you actually click the web button, grab the door handle, or move your robotic leg.
Even more impressive is the resolution. Sound waves seem omnipresent, but with focused ultrasound, it’s possible to measure brain activity at a resolution of 100 microns—roughly 10 neurons in the brain.
A Cyborg Future?
Before you start worrying about scientists blasting your brain with sound waves to hack your mind, don’t worry. The new tech still requires skull surgery, meaning that a small chunk of skull needs to be removed. However, the brain itself is spared. This means that compared to electrodes, ultrasound could offer less damage and potentially a far longer mind reading than anything currently possible.
There are downsides. Focused ultrasound is far younger than any electrode-based neural implants, and can’t yet reliably decode 360-degree movement or fine finger movements. For now, the tech requires a wire to link the device to a computer, which is off-putting to many people and will prevent widespread adoption. Add to that the inherent downside of focused ultrasound, which lags behind electrical recordings by roughly two seconds.
All that aside, however, the tech is just tiptoeing into a future where minds and machines seamlessly connect. Ultrasound can penetrate the skull, though not yet at the resolution needed for imaging and decoding brain activity. The team is already working with human volunteers with traumatic brain injuries, who had to have a piece of their skulls removed, to see how well ultrasound works for reading their minds.
“What’s most exciting is that functional ultrasound is a young technique with huge potential. This is just our first step in bringing high performance, less invasive brain-machine interface to more people,” said Norman.
Image Credit: Free-Photos / Pixabay Continue reading
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#439032 To Learn To Deal With Uncertainty, This ...
AI is endowing robots, autonomous vehicles and countless of other forms of tech with new abilities and levels of self-sufficiency. Yet these models faithfully “make decisions” based on whatever data is fed into them, which could have dangerous consequences. For instance, if an autonomous car is driving down a highway and the sensor picks up a confusing signal (e.g., a paint smudge that is incorrectly interpreted as a lane marking), this could cause the car to swerve into another lane unnecessarily.
But in the ever-evolving world of AI, researchers are developing new ways to address challenges like this. One group of researchers has devised a new algorithm that allows the AI model to account for uncertain data, which they describe in a study published February 15 in IEEE Transactions on Neural Networks and Learning Systems.
“While we would like robots to work seamlessly in the real world, the real world is full of uncertainty,” says Michael Everett, a post-doctoral associate at MIT who helped develop the new approach. “It's important for a system to be aware of what it knows and what it is unsure about, which has been a major challenge for modern AI.”
His team focused on a type of AI called reinforcement learning (RL), whereby the model tries to learn the “value” of taking each action in a given scenario through trial-and-error. They developed a secondary algorithm, called Certified Adversarial Robustness for deep RL (CARRL), that can be built on top of an existing RL model.
“Our key innovation is that rather than blindly trusting the measurements, as is done today [by AI models], our algorithm CARRL thinks through all possible measurements that could have been made, and makes a decision that considers the worst-case outcome,” explains Everett.
In their study, the researchers tested CARRL across several different tasks, including collision avoidance simulations and Atari pong. For younger readers who may not be familiar with it, Atari pong is a classic computer game whereby an electronic paddle is used to direct a ping pong on the screen. In the test scenario, CARRL helped move the paddle slightly higher or lower to compensate for the possibility that the ball could approach at a slightly different point than what the input data indicated. All the while, CARRL would try to ensure that the ball would make contact with at least some part of paddle.
Gif: MIT Aerospace Controls Laboratory
In a perfect world, the information that an AI model is fed would be accurate all the time and AI model will perform well (left). But in some cases, the AI may be given inaccurate data, causing it to miss its targets (middle). The new algorithm CARRL helps AIs account for uncertainty in its data inputs, yielding a better performance when relying on poor data (right).
Across all test scenarios, the RL model was better at compensating for potential inaccurate or “noisy” data with CARRL, than without CARRL.
But the results also show that, like with humans, too much self-doubt and uncertainty can be unhelpful. In the collision avoidance scenario, for example, indulging in too much uncertainty caused the main moving object in the simulation to avoid both the obstacle and its goal. “There is definitely a limit to how ‘skeptical’ the algorithm can be without becoming overly conservative,” Everett says.
This research was funded by Ford Motor Company, but Everett notes that it could be applicable under many other commercial applications requiring safety-aware AI, including aerospace, healthcare, or manufacturing domains.
“This work is a step toward my vision of creating ‘certifiable learning machines’—systems that can discover how to explore and perform in the real world on their own, while still having safety and robustness guarantees,” says Everett. “We'd like to bring CARRL into robotic hardware while continuing to explore the theoretical challenges at the interface of robotics and AI.” Continue reading
Posted in Human Robots
#438982 Quantum Computing and Reinforcement ...
Deep reinforcement learning is having a superstar moment.
Powering smarter robots. Simulating human neural networks. Trouncing physicians at medical diagnoses and crushing humanity’s best gamers at Go and Atari. While far from achieving the flexible, quick thinking that comes naturally to humans, this powerful machine learning idea seems unstoppable as a harbinger of better thinking machines.
Except there’s a massive roadblock: they take forever to run. Because the concept behind these algorithms is based on trial and error, a reinforcement learning AI “agent” only learns after being rewarded for its correct decisions. For complex problems, the time it takes an AI agent to try and fail to learn a solution can quickly become untenable.
But what if you could try multiple solutions at once?
This week, an international collaboration led by Dr. Philip Walther at the University of Vienna took the “classic” concept of reinforcement learning and gave it a quantum spin. They designed a hybrid AI that relies on both quantum and run-of-the-mill classic computing, and showed that—thanks to quantum quirkiness—it could simultaneously screen a handful of different ways to solve a problem.
The result is a reinforcement learning AI that learned over 60 percent faster than its non-quantum-enabled peers. This is one of the first tests that shows adding quantum computing can speed up the actual learning process of an AI agent, the authors explained.
Although only challenged with a “toy problem” in the study, the hybrid AI, once scaled, could impact real-world problems such as building an efficient quantum internet. The setup “could readily be integrated within future large-scale quantum communication networks,” the authors wrote.
The Bottleneck
Learning from trial and error comes intuitively to our brains.
Say you’re trying to navigate a new convoluted campground without a map. The goal is to get from the communal bathroom back to your campsite. Dead ends and confusing loops abound. We tackle the problem by deciding to turn either left or right at every branch in the road. One will get us closer to the goal; the other leads to a half hour of walking in circles. Eventually, our brain chemistry rewards correct decisions, so we gradually learn the correct route. (If you’re wondering…yeah, true story.)
Reinforcement learning AI agents operate in a similar trial-and-error way. As a problem becomes more complex, the number—and time—of each trial also skyrockets.
“Even in a moderately realistic environment, it may simply take too long to rationally respond to a given situation,” explained study author Dr. Hans Briegel at the Universität Innsbruck in Austria, who previously led efforts to speed up AI decision-making using quantum mechanics. If there’s pressure that allows “only a certain time for a response, an agent may then be unable to cope with the situation and to learn at all,” he wrote.
Many attempts have tried speeding up reinforcement learning. Giving the AI agent a short-term “memory.” Tapping into neuromorphic computing, which better resembles the brain. In 2014, Briegel and colleagues showed that a “quantum brain” of sorts can help propel an AI agent’s decision-making process after learning. But speeding up the learning process itself has eluded our best attempts.
The Hybrid AI
The new study went straight for that previously untenable jugular.
The team’s key insight was to tap into the best of both worlds—quantum and classical computing. Rather than building an entire reinforcement learning system using quantum mechanics, they turned to a hybrid approach that could prove to be more practical. Here, the AI agent uses quantum weirdness as it’s trying out new approaches—the “trial” in trial and error. The system then passes the baton to a classical computer to give the AI its reward—or not—based on its performance.
At the heart of the quantum “trial” process is a quirk called superposition. Stay with me. Our computers are powered by electrons, which can represent only two states—0 or 1. Quantum mechanics is far weirder, in that photons (particles of light) can simultaneously be both 0 and 1, with a slightly different probability of “leaning towards” one or the other.
This noncommittal oddity is part of what makes quantum computing so powerful. Take our reinforcement learning example of navigating a new campsite. In our classic world, we—and our AI—need to decide between turning left or right at an intersection. In a quantum setup, however, the AI can (in a sense) turn left and right at the same time. So when searching for the correct path back to home base, the quantum system has a leg up in that it can simultaneously explore multiple routes, making it far faster than conventional, consecutive trail and error.
“As a consequence, an agent that can explore its environment in superposition will learn significantly faster than its classical counterpart,” said Briegel.
It’s not all theory. To test out their idea, the team turned to a programmable chip called a nanophotonic processor. Think of it as a CPU-like computer chip, but it processes particles of light—photons—rather than electricity. These light-powered chips have been a long time in the making. Back in 2017, for example, a team from MIT built a fully optical neural network into an optical chip to bolster deep learning.
The chips aren’t all that exotic. Nanophotonic processors act kind of like our eyeglasses, which can carry out complex calculations that transform light that passes through them. In the glasses case, they let people see better. For a light-based computer chip, it allows computation. Rather than using electrical cables, the chips use “wave guides” to shuttle photons and perform calculations based on their interactions.
The “error” or “reward” part of the new hardware comes from a classical computer. The nanophotonic processor is coupled to a traditional computer, where the latter provides the quantum circuit with feedback—that is, whether to reward a solution or not. This setup, the team explains, allows them to more objectively judge any speed-ups in learning in real time.
In this way, a hybrid reinforcement learning agent alternates between quantum and classical computing, trying out ideas in wibbly-wobbly “multiverse” land while obtaining feedback in grounded, classic physics “normality.”
A Quantum Boost
In simulations using 10,000 AI agents and actual experimental data from 165 trials, the hybrid approach, when challenged with a more complex problem, showed a clear leg up.
The key word is “complex.” The team found that if an AI agent has a high chance of figuring out the solution anyway—as for a simple problem—then classical computing works pretty well. The quantum advantage blossoms when the task becomes more complex or difficult, allowing quantum mechanics to fully flex its superposition muscles. For these problems, the hybrid AI was 63 percent faster at learning a solution compared to traditional reinforcement learning, decreasing its learning effort from 270 guesses to 100.
Now that scientists have shown a quantum boost for reinforcement learning speeds, the race for next-generation computing is even more lit. Photonics hardware required for long-range light-based communications is rapidly shrinking, while improving signal quality. The partial-quantum setup could “aid specifically in problems where frequent search is needed, for example, network routing problems” that’s prevalent for a smooth-running internet, the authors wrote. With a quantum boost, reinforcement learning may be able to tackle far more complex problems—those in the real world—than currently possible.
“We are just at the beginning of understanding the possibilities of quantum artificial intelligence,” said lead author Walther.
Image Credit: Oleg Gamulinskiy from Pixabay Continue reading
Posted in Human Robots