Tag Archives: Space

#436578 AI Just Discovered a New Antibiotic to ...

Posted on February 24, 2020 by Android

Penicillin, one of the greatest discoveries in the history of medicine, was a product of chance.

After returning from summer vacation in September 1928, bacteriologist Alexander Fleming found a colony of bacteria he’d left in his London lab had sprouted a fungus. Curiously, wherever the bacteria contacted the fungus, their cell walls broke down and they died. Fleming guessed the fungus was secreting something lethal to the bacteria—and the rest is history.

Fleming’s discovery of penicillin and its later isolation, synthesis, and scaling in the 1940s released a flood of antibiotic discoveries in the next few decades. Bacteria and fungi had been waging an ancient war against each other, and the weapons they’d evolved over eons turned out to be humanity’s best defense against bacterial infection and disease.

In recent decades, however, the flood of new antibiotics has slowed to a trickle.

Their development is uneconomical for drug companies, and the low-hanging fruit has long been picked. We’re now facing the emergence of strains of super bacteria resistant to one or more antibiotics and an aging arsenal to fight them with. Gone unchallenged, an estimated 700,000 deaths worldwide due to drug resistance could rise to as many as 10 million in 2050.

Increasingly, scientists warn the tide is turning, and we need a new strategy to keep pace with the remarkably quick and boundlessly creative tactics of bacterial evolution.

But where the golden age of antibiotics was sparked by serendipity, human intelligence, and natural molecular weapons, its sequel may lean on the uncanny eye of artificial intelligence to screen millions of compounds—and even design new ones—in search of the next penicillin.

Hal Discovers a Powerful Antibiotic
In a paper published this week in the journal, Cell, MIT researchers took a step in this direction. The team says their machine learning algorithm discovered a powerful new antibiotic.

Named for the AI in 2001: A Space Odyssey, the antibiotic, halicin, successfully wiped out dozens of bacterial strains, including some of the most dangerous drug-resistant bacteria on the World Health Organization’s most wanted list. The bacteria also failed to develop resistance to E. coli during a month of observation, in stark contrast to existing antibiotic ciprofloxacin.

“In terms of antibiotic discovery, this is absolutely a first,” Regina Barzilay, a senior author on the study and computer science professor at MIT, told The Guardian.

The algorithm that discovered halicin was trained on the molecular features of 2,500 compounds. Nearly half were FDA-approved drugs, and another 800 naturally occurring. The researchers specifically tuned the algorithm to look for molecules with antibiotic properties but whose structures would differ from existing antibiotics (as halicin’s does). Using another machine learning program, they screened the results for those likely to be safe for humans.

Early study suggests halicin attacks the bacteria’s cell membranes, disrupting their ability to produce energy. Protecting the cell membrane from halicin might take more than one or two genetic mutations, which could account for its impressive ability to prevent resistance.

“I think this is one of the more powerful antibiotics that has been discovered to date,” James Collins, an MIT professor of bioengineering and senior author told The Guardian. “It has remarkable activity against a broad range of antibiotic-resistant pathogens.”

Beyond tests in petri-dish bacterial colonies, the team also tested halicin in mice. The antibiotic cleared up infections of a strain of bacteria resistant to all known antibiotics in a day. The team plans further study in partnership with a pharmaceutical company or nonprofit, and they hope to eventually prove it safe and effective for use in humans.

This last bit remains the trickiest step, given the cost of getting a new drug approved. But Collins hopes algorithms like theirs will help. “We could dramatically reduce the cost required to get through clinical trials,” he told the Financial Times.

A Universe of Drugs Awaits
The bigger story may be what happens next.

How many novel antibiotics await discovery, and how far can AI screening take us? The initial 6,000 compounds scanned by Barzilay and Collins’s team is a drop in the bucket.

They’ve already begun digging deeper by setting the algorithm loose on 100 million molecules from an online library of 1.5 billion compounds called the ZINC15 database. This first search took three days and turned up 23 more candidates that, like halicin, differ structurally from existing antibiotics and may be safe for humans. Two of these—which the team will study further—appear to be especially powerful.

Even more ambitiously, Barzilay hopes the approach can find or even design novel antibiotics that kill bad bacteria with alacrity while sparing the good guys. In this way, a round of antibiotics would cure whatever ails you without taking out your whole gut microbiome in the process.

All this is part of a larger movement to use machine learning algorithms in the long, expensive process of drug discovery. Other players in the area are also training AI on the vast possibility space of drug-like compounds. Last fall, one of the leaders in the area, Insilico, was challenged by a partner to see just how fast their method could do the job. The company turned out a new a proof-of-concept drug candidate in only 46 days.

The field is still developing, however, and it has yet to be seen exactly how valuable these approaches will be in practice. Barzilay is optimistic though.

“There is still a question of whether machine-learning tools are really doing something intelligent in healthcare, and how we can develop them to be workhorses in the pharmaceuticals industry,” she said. “This shows how far you can adapt this tool.”

Image Credit: Halicin (top row) prevented the development of antibiotic resistance in E. coli, while ciprofloxacin (bottom row) did not. Collins Lab at MIT Continue reading →

Posted in Human Robots

#436550 Work in the Age of Web 3.0

Posted on February 7, 2020 by Android

What is the future of work? Is our future one of ‘technological socialism’ (where technology is taking care of our needs)? Or will tomorrow’s workplace be completely virtualized, allowing us to hang out at home in our PJs while “walking” about our virtual corporate headquarters?

This blog will look at the future of work during the age of Web 3.0, examining scenarios in which artificial intelligence, virtual reality, and the spatial web converge to transform every element of our careers, from training, to execution, to free time.

To offer a quick recap on what the Spatial Web is and how it works, let’s cover some brief history.

A Quick Recap on Web 3.0
While Web 1.0 consisted of static documents and read-only data (static web pages), Web 2.0 introduced multimedia content, interactive web applications, and participatory social media, all of these mediated by two-dimensional screens.

But over the next two to five years, the convergence of 5G, artificial intelligence, VR/AR, and a trillion-sensor economy will enable us to both map our physical world into virtual space and superimpose a digital data layer onto our physical environments. Suddenly, all our information will be manipulated, stored, understood and experienced in spatial ways.

In this blog, I’ll be discussing the Spatial Web’s vast implications for:

Professional Training
Delocalized Business & the Virtual Workplace
Smart Permissions & Data Security

Let’s dive in.

Virtual Training, Real-World Results
Virtual and augmented reality have already begun disrupting the professional training market. As projected by ABI Research, the enterprise VR training market is on track to exceed $6.3 billion in value by 2022.

Leading the charge, Walmart has already implemented VR across 200 Academy training centers, running over 45 modules and simulating everything from unusual customer requests to a Black Friday shopping rush.

Then in September 2018, Walmart committed to a 17,000-headset order of the Oculus Go to equip every US Supercenter, neighborhood market, and discount store with VR-based employee training. By mid-2019, Walmart had tracked a 10-15 percent boost in employee confidence as a result of newly implemented VR training.

In the engineering world, Bell Helicopter is using VR to massively expedite development and testing of its latest aircraft, FCX-001. Partnering with Sector 5 Digital and HTC VIVE, Bell found it could concentrate a typical 6-year aircraft design process into the course of 6 months, turning physical mock-ups into CAD-designed virtual replicas.

But beyond the design process itself, Bell is now one of a slew of companies pioneering VR pilot tests and simulations with real-world accuracy. Seated in a true-to-life virtual cockpit, pilots have now tested countless iterations of the FCX-001 in virtual flight, drawing directly onto the 3D model and enacting aircraft modifications in real-time.

And in an expansion of our virtual senses, several key players are already working on haptic feedback. In the case of VR flight, French company Go Touch VR is now partnering with software developer FlyInside on fingertip-mounted haptic tech for aviation.

Dramatically reducing time and trouble required for VR-testing pilots, they aim to give touch-based confirmation of every switch and dial activated on virtual flights, just as one would experience in a full-sized cockpit mockup. Replicating texture, stiffness, and even the sensation of holding an object, these piloted devices contain a suite of actuators to simulate everything from a light touch to higher-pressured contact, all controlled by gaze and finger movements.

When it comes to other high-risk simulations, virtual and augmented reality have barely scratched the surface.

Firefighters can now combat virtual wildfires with new platforms like FLAIM Trainer or TargetSolutions. And thanks to the expansion of medical AR/VR services like 3D4Medical or Echopixel, surgeons might soon perform operations on annotated organs and magnified incision sites, speeding up reaction times and vastly improving precision.

But perhaps most urgent, Web 3.0 and its VR interface will offer an immediate solution for today’s constant industry turnover and large-scale re-education demands. VR educational facilities with exact replicas of anything from large industrial equipment to minute circuitry will soon give anyone a second chance at the 21st-century job market.

Want to be an electric, autonomous vehicle mechanic at age 15? Throw on a demonetized VR module and learn by doing, testing your prototype iterations at almost zero cost and with no risk of harming others.

Want to be a plasma physicist and play around with a virtual nuclear fusion reactor? Now you’ll be able to simulate results and test out different tweaks, logging Smart Educational Record credits in the process.

As tomorrow’s career model shifts from a “one-and-done graduate degree” to continuous lifelong education, professional VR-based re-education will allow for a continuous education loop, reducing the barrier to entry for anyone wanting to enter a new industry.

But beyond professional training and virtually enriched, real-world work scenarios, Web 3.0 promises entirely virtual workplaces and blockchain-secured authorization systems.

Rise of the Virtual Workplace & Digital Data Integrity
In addition to enabling a virtual goods marketplace, the Spatial Web is also giving way to “virtual company headquarters” and completely virtualized companies, where employees can work from home or any place on the planet.

Too good to be true? Check out an incredible publicly listed company called eXp Realty.

Launched on the heels of the 2008 financial crisis, eXp Realty beat the odds, going public this past May and surpassing a $1B market cap on day one of trading. But how? Opting for a demonetized virtual model, eXp’s founder Glenn Sanford decided to ditch brick and mortar from the get-go, instead building out an online virtual campus for employees, contractors, and thousands of agents.

And after years of hosting team meetings, training seminars, and even agent discussions with potential buyers through 2D digital interfaces, eXp’s virtual headquarters went spatial. What is eXp’s primary corporate value? FUN! And Glenn Sanford’s employees love their jobs.

In a bid to transition from 2D interfaces to immersive, 3D work experiences, virtual platform VirBELA built out the company’s office space in VR, unlocking indefinite scaling potential and an extraordinary new precedent. Foregoing any physical locations for a centralized VR campus, eXp Realty has essentially thrown out all overhead and entered a lucrative market with barely any upfront costs.

Delocalize with VR, and you can now hire anyone with Internet access (right next door or on the other side of the planet), redesign your corporate office every month, throw in an ocean-view office or impromptu conference room for client meetings, and forget about guzzled-up hours in traffic.

Throw in the Spatial Web’s fundamental blockchain-based data layer, and now cryptographically secured virtual IDs will let you validate colleagues’ identities or any of the virtual avatars we will soon inhabit.

This becomes critically important for spatial information logs—keeping incorruptible records of who’s present at a meeting, which data each person has access to, and AI-translated reports of everything discussed and contracts agreed to.

But as I discussed in a previous Spatial Web blog, not only will Web 3.0 and VR advancements allow us to build out virtual worlds, but we’ll soon be able to digitally map our real-world physical offices or entire commercial high rises too.

As data gets added and linked to any given employee’s office, conference room, or security system, we might then access online-merge-offline environments and information through augmented reality.

Imagine showing up at your building’s concierge and your AR glasses automatically check you into the building, authenticating your identity and pulling up any reminders you’ve linked to that specific location.

You stop by a friend’s office, and his smart security system lets you know he’ll arrive in an hour. Need to book a public conference room that’s already been scheduled by another firm’s marketing team? Offer to pay them a fee and, once accepted, a smart transaction will automatically deliver a payment to their company account.

With blockchain-verified digital identities, spatially logged data, and virtually manifest information, business logistics take a fraction of the time, operations grow seamless, and corporate data will be safer than ever.

Final Thoughts
While converging technologies slash the lifespan of Fortune 500 companies, bring on the rise of vast new industries, and transform the job market, Web 3.0 is changing the way we work, where we work, and who we work with.

Life-like virtual modules are already unlocking countless professional training camps, modifiable in real time and easily updated. Virtual programming and blockchain-based authentication are enabling smart data logging, identity protection, and on-demand smart asset trading. And VR/AR-accessible worlds (and corporate campuses) not only demonetize, dematerialize, and delocalize our everyday workplaces, but enrich our physical worlds with AI-driven, context-specific data.

Welcome to the Spatial Web workplace.

Join Me
(1) A360 Executive Mastermind: If you’re an exponentially and abundance-minded entrepreneur who would like coaching directly from me, consider joining my Abundance 360 Mastermind, a highly selective community of 360 CEOs and entrepreneurs who I coach for 3 days every January in Beverly Hills, Ca. Through A360, I provide my members with context and clarity about how converging exponential technologies will transform every industry. I’m committed to running A360 for the course of an ongoing 25-year journey as a “countdown to the Singularity.”

If you’d like to learn more and consider joining our 2021 membership, apply here.

(2) Abundance-Digital Online Community: I’ve also created a Digital/Online community of bold, abundance-minded entrepreneurs called Abundance-Digital. Abundance-Digital is Singularity University’s ‘onramp’ for exponential entrepreneurs—those who want to get involved and play at a higher level. Click here to learn more.

(Both A360 and Abundance-Digital are part of Singularity University—your participation opens you to a global community.)

This article originally appeared on diamandis.com. Read the original article here.

Image Credit: Image by Gerd Altmann from Pixabay Continue reading →

Posted in Human Robots

#436530 How Smart Roads Will Make Driving ...

Posted on January 30, 2020 by Android

Roads criss-cross the landscape, but while they provide vital transport links, in many ways they represent a huge amount of wasted space. Advances in “smart road” technology could change that, creating roads that can harvest energy from cars, detect speeding, automatically weigh vehicles, and even communicate with smart cars.

“Smart city” projects are popping up in countries across the world thanks to advances in wireless communication, cloud computing, data analytics, remote sensing, and artificial intelligence. Transportation is a crucial element of most of these plans, but while much of the focus is on public transport solutions, smart roads are increasingly being seen as a crucial feature of these programs.

New technology is making it possible to tackle a host of issues including traffic congestion, accidents, and pollution, say the authors of a paper in the journal Proceedings of the Royal Society A. And they’ve outlined ten of the most promising advances under development or in planning stages that could feature on tomorrow’s roads.

Energy harvesting

A variety of energy harvesting technologies integrated into roads have been proposed as ways to power street lights and traffic signals or provide a boost to the grid. Photovoltaic panels could be built into the road surface to capture sunlight, or piezoelectric materials installed beneath the asphalt could generate current when deformed by vehicles passing overhead.

Musical roads

Countries like Japan, Denmark, the Netherlands, Taiwan, and South Korea have built roads that play music as cars pass by. By varying the spacing of rumble strips, it’s possible to produce a series of different notes as vehicles drive over them. The aim is generally to warn of hazards or help drivers keep to the speed limit.

Automatic weighing

Weight-in-motion technology that measures vehicles’ loads as they drive slowly through a designated lane has been around since the 1970s, but more recently high speed weight-in-motion tech has made it possible to measure vehicles as they travel at regular highway speeds. The latest advance has been integration with automatic licence plate reading and wireless communication to allow continuous remote monitoring both to enforce weight restrictions and monitor wear on roads.

Vehicle charging

The growing popularity of electric vehicles has spurred the development of technology to charge cars and buses as they drive. The most promising of these approaches is magnetic induction, which involves burying cables beneath the road to generate electromagnetic fields that a receiver device in the car then transforms into electrical power to charge batteries.

Smart traffic signs

Traffic signs aren’t always as visible as they should be, and it can often be hard to remember what all of them mean. So there are now proposals for “smart signs” that wirelessly beam a sign’s content to oncoming cars fitted with receivers, which can then alert the driver verbally or on the car’s display. The approach isn’t affected by poor weather and lighting, can be reprogrammed easily, and could do away with the need for complex sign recognition technology in future self-driving cars.

Traffic violation detection and notification

Sensors and cameras can be combined with these same smart signs to detect and automatically notify drivers of traffic violations. The automatic transmission of traffic signals means drivers won’t be able to deny they’ve seen the warnings or been notified of any fines, as a record will be stored on their car’s black box.

Talking cars

Car-to-car communication technology and V2X, which lets cars share information with any other connected device, are becoming increasingly common. Inter-car communication can be used to propagate accidents or traffic jam alerts to prevent congestion, while letting vehicles communicate with infrastructure can help signals dynamically manage timers to keep traffic flowing or automatically collect tolls.

Smart intersections

Combing sensors and cameras with object recognition systems that can detect vehicles and other road users can help increase safety and efficiency at intersections. It can be used to extend green lights for slower road users like pedestrians and cyclists, sense jaywalkers, give priority to emergency vehicles, and dynamically adjust light timers to optimize traffic flow. Information can even be broadcast to oncoming vehicles to highlight blind spots and potential hazards.

Automatic crash detection

There’s a “golden hour” after an accident in which the chance of saving lives is greatly increased. Vehicle communication technology can ensure that notification of a crash reaches the emergency services rapidly, and can also provide vital information about the number and type of vehicles involved, which can help emergency response planning. It can also be used to alert other drivers to slow down or stop to prevent further accidents.

Smart street lights

Street lights are increasingly being embedded with sensors, wireless connectivity, and micro-controllers to enable a variety of smart functions. These include motion activation to save energy, providing wireless access points, air quality monitoring, or parking and litter monitoring. This can also be used to send automatic maintenance requests if a light is faulty, and can even allow neighboring lights to be automatically brightened to compensate.

Image Credit: Image by David Mark from Pixabay Continue reading →

Posted in Human Robots

#436504 20 Technology Metatrends That Will ...

Posted on January 10, 2020 by Android

In the decade ahead, waves of exponential technological advancements are stacking atop one another, eclipsing decades of breakthroughs in scale and impact.

Emerging from these waves are 20 “metatrends” likely to revolutionize entire industries (old and new), redefine tomorrow’s generation of businesses and contemporary challenges, and transform our livelihoods from the bottom up.

Among these metatrends are augmented human longevity, the surging smart economy, AI-human collaboration, urbanized cellular agriculture, and high-bandwidth brain-computer interfaces, just to name a few.

It is here that master entrepreneurs and their teams must see beyond the immediate implications of a given technology, capturing second-order, Google-sized business opportunities on the horizon.

Welcome to a new decade of runaway technological booms, historic watershed moments, and extraordinary abundance.

Let’s dive in.

20 Metatrends for the 2020s
(1) Continued increase in global abundance: The number of individuals in extreme poverty continues to drop, as the middle-income population continues to rise. This metatrend is driven by the convergence of high-bandwidth and low-cost communication, ubiquitous AI on the cloud, and growing access to AI-aided education and AI-driven healthcare. Everyday goods and services (finance, insurance, education, and entertainment) are being digitized and becoming fully demonetized, available to the rising billion on mobile devices.

(2) Global gigabit connectivity will connect everyone and everything, everywhere, at ultra-low cost: The deployment of both licensed and unlicensed 5G, plus the launch of a multitude of global satellite networks (OneWeb, Starlink, etc.), allow for ubiquitous, low-cost communications for everyone, everywhere, not to mention the connection of trillions of devices. And today’s skyrocketing connectivity is bringing online an additional three billion individuals, driving tens of trillions of dollars into the global economy. This metatrend is driven by the convergence of low-cost space launches, hardware advancements, 5G networks, artificial intelligence, materials science, and surging computing power.

(3) The average human healthspan will increase by 10+ years: A dozen game-changing biotech and pharmaceutical solutions (currently in Phase 1, 2, or 3 clinical trials) will reach consumers this decade, adding an additional decade to the human healthspan. Technologies include stem cell supply restoration, wnt pathway manipulation, senolytic medicines, a new generation of endo-vaccines, GDF-11, and supplementation of NMD/NAD+, among several others. And as machine learning continues to mature, AI is set to unleash countless new drug candidates, ready for clinical trials. This metatrend is driven by the convergence of genome sequencing, CRISPR technologies, AI, quantum computing, and cellular medicine.

(4) An age of capital abundance will see increasing access to capital everywhere: From 2016 – 2018 (and likely in 2019), humanity hit all-time highs in the global flow of seed capital, venture capital, and sovereign wealth fund investments. While this trend will witness some ups and downs in the wake of future recessions, it is expected to continue its overall upward trajectory. Capital abundance leads to the funding and testing of ‘crazy’ entrepreneurial ideas, which in turn accelerate innovation. Already, $300 billion in crowdfunding is anticipated by 2025, democratizing capital access for entrepreneurs worldwide. This metatrend is driven by the convergence of global connectivity, dematerialization, demonetization, and democratization.

(5) Augmented reality and the spatial web will achieve ubiquitous deployment: The combination of augmented reality (yielding Web 3.0, or the spatial web) and 5G networks (offering 100Mb/s – 10Gb/s connection speeds) will transform how we live our everyday lives, impacting every industry from retail and advertising to education and entertainment. Consumers will play, learn, and shop throughout the day in a newly intelligent, virtually overlaid world. This metatrend will be driven by the convergence of hardware advancements, 5G networks, artificial intelligence, materials science, and surging computing power.

(6) Everything is smart, embedded with intelligence: The price of specialized machine learning chips is dropping rapidly with a rise in global demand. Combined with the explosion of low-cost microscopic sensors and the deployment of high-bandwidth networks, we’re heading into a decade wherein every device becomes intelligent. Your child’s toy remembers her face and name. Your kids’ drone safely and diligently follows and videos all the children at the birthday party. Appliances respond to voice commands and anticipate your needs.

(7) AI will achieve human-level intelligence: As predicted by technologist and futurist Ray Kurzweil, artificial intelligence will reach human-level performance this decade (by 2030). Through the 2020s, AI algorithms and machine learning tools will be increasingly made open source, available on the cloud, allowing any individual with an internet connection to supplement their cognitive ability, augment their problem-solving capacity, and build new ventures at a fraction of the current cost. This metatrend will be driven by the convergence of global high-bandwidth connectivity, neural networks, and cloud computing. Every industry, spanning industrial design, healthcare, education, and entertainment, will be impacted.

(8) AI-human collaboration will skyrocket across all professions: The rise of “AI as a Service” (AIaaS) platforms will enable humans to partner with AI in every aspect of their work, at every level, in every industry. AIs will become entrenched in everyday business operations, serving as cognitive collaborators to employees—supporting creative tasks, generating new ideas, and tackling previously unattainable innovations. In some fields, partnership with AI will even become a requirement. For example: in the future, making certain diagnoses without the consultation of AI may be deemed malpractice.

(9) Most individuals adapt a JARVIS-like “software shell” to improve their quality of life: As services like Alexa, Google Home, and Apple Homepod expand in functionality, such services will eventually travel beyond the home and become your cognitive prosthetic 24/7. Imagine a secure JARVIS-like software shell that you give permission to listen to all your conversations, read your email, monitor your blood chemistry, etc. With access to such data, these AI-enabled software shells will learn your preferences, anticipate your needs and behavior, shop for you, monitor your health, and help you problem-solve in support of your mid- and long-term goals.

(10) Globally abundant, cheap renewable energy: Continued advancements in solar, wind, geothermal, hydroelectric, nuclear, and localized grids will drive humanity towards cheap, abundant, and ubiquitous renewable energy. The price per kilowatt-hour will drop below one cent per kilowatt-hour for renewables, just as storage drops below a mere three cents per kilowatt-hour, resulting in the majority displacement of fossil fuels globally. And as the world’s poorest countries are also the world’s sunniest, the democratization of both new and traditional storage technologies will grant energy abundance to those already bathed in sunlight.

(11) The insurance industry transforms from “recovery after risk” to “prevention of risk”: Today, fire insurance pays you after your house burns down; life insurance pays your next-of-kin after you die; and health insurance (which is really sick insurance) pays only after you get sick. This next decade, a new generation of insurance providers will leverage the convergence of machine learning, ubiquitous sensors, low-cost genome sequencing, and robotics to detect risk, prevent disaster, and guarantee safety before any costs are incurred.

(12) Autonomous vehicles and flying cars will redefine human travel (soon to be far faster and cheaper): Fully autonomous vehicles, car-as-a-service fleets, and aerial ride-sharing (flying cars) will be fully operational in most major metropolitan cities in the coming decade. The cost of transportation will plummet 3-4X, transforming real estate, finance, insurance, the materials economy, and urban planning. Where you live and work, and how you spend your time, will all be fundamentally reshaped by this future of human travel. Your kids and elderly parents will never drive. This metatrend will be driven by the convergence of machine learning, sensors, materials science, battery storage improvements, and ubiquitous gigabit connections.

(13) On-demand production and on-demand delivery will birth an “instant economy of things”: Urban dwellers will learn to expect “instant fulfillment” of their retail orders as drone and robotic last-mile delivery services carry products from local supply depots directly to your doorstep. Further riding the deployment of regional on-demand digital manufacturing (3D printing farms), individualized products can be obtained within hours, anywhere, anytime. This metatrend is driven by the convergence of networks, 3D printing, robotics, and artificial intelligence.

(14) Ability to sense and know anything, anytime, anywhere: We’re rapidly approaching the era wherein 100 billion sensors (the Internet of Everything) is monitoring and sensing (imaging, listening, measuring) every facet of our environments, all the time. Global imaging satellites, drones, autonomous car LIDARs, and forward-looking augmented reality (AR) headset cameras are all part of a global sensor matrix, together allowing us to know anything, anytime, anywhere. This metatrend is driven by the convergence of terrestrial, atmospheric and space-based sensors, vast data networks, and machine learning. In this future, it’s not “what you know,” but rather “the quality of the questions you ask” that will be most important.

(15) Disruption of advertising: As AI becomes increasingly embedded in everyday life, your custom AI will soon understand what you want better than you do. In turn, we will begin to both trust and rely upon our AIs to make most of our buying decisions, turning over shopping to AI-enabled personal assistants. Your AI might make purchases based upon your past desires, current shortages, conversations you’ve allowed your AI to listen to, or by tracking where your pupils focus on a virtual interface (i.e. what catches your attention). As a result, the advertising industry—which normally competes for your attention (whether at the Superbowl or through search engines)—will have a hard time influencing your AI. This metatrend is driven by the convergence of machine learning, sensors, augmented reality, and 5G/networks.

(16) Cellular agriculture moves from the lab into inner cities, providing high-quality protein that is cheaper and healthier: This next decade will witness the birth of the most ethical, nutritious, and environmentally sustainable protein production system devised by humankind. Stem cell-based ‘cellular agriculture’ will allow the production of beef, chicken, and fish anywhere, on-demand, with far higher nutritional content, and a vastly lower environmental footprint than traditional livestock options. This metatrend is enabled by the convergence of biotechnology, materials science, machine learning, and AgTech.

(17) High-bandwidth brain-computer interfaces (BCIs) will come online for public use: Technologist and futurist Ray Kurzweil has predicted that in the mid-2030s, we will begin connecting the human neocortex to the cloud. This next decade will see tremendous progress in that direction, first serving those with spinal cord injuries, whereby patients will regain both sensory capacity and motor control. Yet beyond assisting those with motor function loss, several BCI pioneers are now attempting to supplement their baseline cognitive abilities, a pursuit with the potential to increase their sensorium, memory, and even intelligence. This metatrend is fueled by the convergence of materials science, machine learning, and robotics.

(18) High-resolution VR will transform both retail and real estate shopping: High-resolution, lightweight virtual reality headsets will allow individuals at home to shop for everything from clothing to real estate from the convenience of their living room. Need a new outfit? Your AI knows your detailed body measurements and can whip up a fashion show featuring your avatar wearing the latest 20 designs on a runway. Want to see how your furniture might look inside a house you’re viewing online? No problem! Your AI can populate the property with your virtualized inventory and give you a guided tour. This metatrend is enabled by the convergence of: VR, machine learning, and high-bandwidth networks.

(19) Increased focus on sustainability and the environment: An increase in global environmental awareness and concern over global warming will drive companies to invest in sustainability, both from a necessity standpoint and for marketing purposes. Breakthroughs in materials science, enabled by AI, will allow companies to drive tremendous reductions in waste and environmental contamination. One company’s waste will become another company’s profit center. This metatrend is enabled by the convergence of materials science, artificial intelligence, and broadband networks.

(20) CRISPR and gene therapies will minimize disease: A vast range of infectious diseases, ranging from AIDS to Ebola, are now curable. In addition, gene-editing technologies continue to advance in precision and ease of use, allowing families to treat and ultimately cure hundreds of inheritable genetic diseases. This metatrend is driven by the convergence of various biotechnologies (CRISPR, gene therapy), genome sequencing, and artificial intelligence.

Join Me
(1) A360 Executive Mastermind: If you’re an exponentially and abundance-minded entrepreneur who would like coaching directly from me, consider joining my Abundance 360 Mastermind, a highly selective community of 360 CEOs and entrepreneurs who I coach for 3 days every January in Beverly Hills, Ca. Through A360, I provide my members with context and clarity about how converging exponential technologies will transform every industry. I’m committed to running A360 for the course of an ongoing 25-year journey as a “countdown to the Singularity.”

If you’d like to learn more and consider joining our 2020 membership, apply here.

(2) Abundance-Digital Online Community: I’ve also created a Digital/Online community of bold, abundance-minded entrepreneurs called Abundance-Digital. Abundance-Digital is Singularity University’s ‘onramp’ for exponential entrepreneurs — those who want to get involved and play at a higher level. Click here to learn more.

(Both A360 and Abundance-Digital are part of Singularity University — your participation opens you to a global community.)

This article originally appeared on diamandis.com. Read the original article here.

Image Credit: Image by Free-Photos from Pixabay Continue reading →

Posted in Human Robots

#436488 Tech’s Biggest Leaps From the Last 10 ...

Posted on January 3, 2020 by Android

As we enter our third decade in the 21st century, it seems appropriate to reflect on the ways technology developed and note the breakthroughs that were achieved in the last 10 years.

The 2010s saw IBM’s Watson win a game of Jeopardy, ushering in mainstream awareness of machine learning, along with DeepMind’s AlphaGO becoming the world’s Go champion. It was the decade that industrial tools like drones, 3D printers, genetic sequencing, and virtual reality (VR) all became consumer products. And it was a decade in which some alarming trends related to surveillance, targeted misinformation, and deepfakes came online.

For better or worse, the past decade was a breathtaking era in human history in which the idea of exponential growth in information technologies powered by computation became a mainstream concept.

As I did last year for 2018 only, I’ve asked a collection of experts across the Singularity University faculty to help frame the biggest breakthroughs and moments that gave shape to the past 10 years. I asked them what, in their opinion, was the most important breakthrough in their respective fields over the past decade.

My own answer to this question, focused in the space of augmented and virtual reality, would be the stunning announcement in March of 2014 that Facebook acquired Oculus VR for $2 billion. Although VR technology had been around for a while, it was at this precise moment that VR arrived as a consumer technology platform. Facebook, largely fueled by the singular interest of CEO Mark Zuckerberg, has funded the development of this industry, keeping alive the hope that consumer VR can become a sustainable business. In the meantime, VR has continued to grow in sophistication and usefulness, though it has yet to truly take off as a mainstream concept. That will hopefully be a development for the 2020s.

Below is a decade in review across the technology areas that are giving shape to our modern world, as described by the SU community of experts.

Digital Biology
Dr. Tiffany Vora | Faculty Director and Vice Chair, Digital Biology and Medicine, Singularity University

In my mind, this decade of astounding breakthroughs in the life sciences and medicine rests on the achievement of the $1,000 human genome in 2016. More-than-exponentially falling costs of DNA sequencing have driven advances in medicine, agriculture, ecology, genome editing, synthetic biology, the battle against climate change, and our fundamental understanding of life and its breathtaking connections. The “digital” revolution in DNA constituted an important model for harnessing other types of biological information, from personalized bio data to massive datasets spanning populations and species.

Crucially, by aggressively driving down the cost of such analyses, researchers and entrepreneurs democratized access to the source code of life—with attendant financial, cultural, and ethical consequences. Exciting, but take heed: Veritas Genetics spearheaded a $600 genome in 2019, only to have to shutter USA operations due to a money trail tangled with the trade war with China. Stay tuned through the early 2020s to see the pricing of DNA sequencing fall even further … and to experience the many ways that cheaper, faster harvesting of biological data will enrich your daily life.

Cryptocurrency
Alex Gladstein | Chief Strategy Officer, Human Rights Foundation

The past decade has seen Bitcoin go from just an idea on an obscure online message board to a global financial network carrying more than 100 billion dollars in value. And we’re just getting started. One recent defining moment in the cryptocurrency space has been a stunning trend underway in Venezuela, where today, the daily dollar-denominated value of Bitcoin traded now far exceeds the daily dollar-denominated value traded on the Caracas Stock Exchange. It’s just one country, but it’s a significant country, and a paradigm shift.

Governments and corporations are following Bitcoin’s success too, and are looking to launch their own digital currencies. China will launch its “DC/EP” project in the coming months, and Facebook is trying to kickstart its Libra project. There are technical and regulatory uncertainties for both, but one thing is for certain: the era of digital currency has arrived.

Business Strategy and Entrepreneurship
Pascal Finnette | Chair, Entrepreneurship and Open Innovation, Singularity University

For me, without a doubt, the most interesting and quite possibly ground-shifting development in the fields of entrepreneurship and corporate innovation in the last ten years is the rapid maturing of customer-driven product development frameworks such as Lean Startup, and its subsequent adoption by corporates for their own innovation purposes.

Tools and frameworks like the Business Model Canvas, agile (software) development and the aforementioned Lean Startup methodology fundamentally shifted the way we think and go about building products, services, and companies, with many of these tools bursting onto the startup scene in the late 2000s and early 2010s.

As these tools matured they found mass adoption not only in startups around the world, but incumbent companies who eagerly adopted them to increase their own innovation velocity and success.

Energy
Ramez Naam | Co-Chair, Energy and Environment, Singularity University

The 2010s were the decade that saw clean electricity, energy storage, and electric vehicles break through price and performance barriers around the world. Solar, wind, batteries, and EVs started this decade as technologies that had to be subsidized. That was the first phase of their existence. Now they’re entering their third, most disruptive phase, where shifting to clean energy and mobility is cheaper than continuing to use existing coal, gas, or oil infrastructure.

Consider that at the start of 2010, there was no place on earth where building new solar or wind was cheaper than building new coal or gas power generation. By 2015, in some of the sunniest and windiest places on earth, solar and wind had entered their second phase, where they were cost-competitive for new power. And then, in 2018 and 2019, we started to see the edge of the third phase, as building new solar and wind, in some parts of the world, was cheaper than operating existing coal or gas power plants.

Food Technology
Liz Specht, Ph. D | Associate Director of Science & Technology, The Good Food Institute

The arrival of mainstream plant-based meat is easily the food tech advance of the decade. Meat analogs have, of course, been around forever. But only in the last decade have companies like Beyond Meat and Impossible Foods decided to cut animals out of the process and build no-compromise meat directly from plants.

Plant-based meat is already transforming the fast-food industry. For example, the introduction of the Impossible Whopper led Burger King to their most profitable quarter in many years. But the global food industry as a whole is shifting as well. Tyson, JBS, Nestle, Cargill, and many others are all embracing plant-based meat.

Augmented and Virtual Reality
Jody Medich | CEO, Superhuman-x

The breakthrough moment for augmented and virtual reality came in 2013 when Palmer Lucky took apart an Android smartphone and added optic lenses to make the first version of the Oculus Rift. Prior to that moment, we struggled with miniaturizing the components needed to develop low-latency head-worn devices. But thanks to the smartphone race started in 2006 with the iPhone, we finally had a suite of sensors, chips, displays, and computing power small enough to put on the head.

What will the next 10 years bring? Look for AR/VR to explode in a big way. We are right on the cusp of that tipping point when the tech is finally “good enough” for our linear expectations. Given all it can do today, we can’t even picture what’s possible. Just as today we can’t function without our phones, by 2029 we’ll feel lost without some AR/VR product. It will be the way we interact with computing, smart objects, and AI. Tim Cook, Apple CEO, predicts it will replace all of today’s computing devices. I can’t wait.

Philosophy of Technology
Alix Rübsaam | Faculty Fellow, Singularity University, Philosophy of Technology/Ethics of AI

The last decade has seen a significant shift in our general attitude towards the algorithms that we now know dictate much of our surroundings. Looking back at the beginning of the decade, it seems we were blissfully unaware of how the data we freely and willingly surrendered would feed the algorithms that would come to shape every aspect of our daily lives: the news we consume, the products we purchase, the opinions we hold, etc.

If I were to isolate a single publication that contributed greatly to the shift in public discourse on algorithms, it would have to be Cathy O’Neil’s Weapons of Math Destruction from 2016. It remains a comprehensive, readable, and highly informative insight into how algorithms dictate our finances, our jobs, where we go to school, or if we can get health insurance. Its publication represents a pivotal moment when the general public started to question whether we should be OK with outsourcing decision making to these opaque systems.

The ubiquity of ethical guidelines for AI and algorithms published just in the last year (perhaps most comprehensively by the AI Now Institute) fully demonstrates the shift in public opinion of this decade.

Data Science
Ola Kowalewski | Faculty Fellow, Singularity University, Data Innovation

In the last decade we entered the era of internet and smartphone ubiquity. The number of internet users doubled, with nearly 60 percent of the global population connected online and now over 35 percent of the globe owns a smartphone. With billions of people in a state of constant connectedness and therefore in a state of constant surveillance, the companies that have built the tech infrastructure and information pipelines have dominated the global economy. This shift from tech companies being the underdogs to arguably the world’s major powers sets the landscape we enter for the next decade.

Global Grand Challenges
Darlene Damm | Vice Chair, Faculty, Global Grand Challenges, Singularity University

The biggest breakthrough over the last decade in social impact and technology is that the social impact sector switched from seeing technology as something problematic to avoid, to one of the most effective ways to create social change. We now see people using exponential technologies to solve all sorts of social challenges in areas ranging from disaster response to hunger to shelter.

The world’s leading social organizations, such as UNICEF and the World Food Programme, have launched their own venture funds and accelerators, and the United Nations recently declared that digitization is revolutionizing global development.

Digital Biology
Raymond McCauley | Chair, Digital Biology, Singularity University, Co-Founder & Chief Architect, BioCurious; Principal, Exponential Biosciences

CRISPR is bringing about a revolution in genetic engineering. It’s obvious, and it’s huge. What may not be so obvious is the widespread adoption of genetic testing. And this may have an even longer-lasting effect. It’s used to test new babies, to solve medical mysteries, and to catch serial killers. Thanks to holiday ads from 23andMe and Ancestry.com, it’s everywhere. Testing your DNA is now a common over-the-counter product. People are using it to set their diet, to pick drugs, and even for dating (or at least picking healthy mates).

And we’re just in the early stages. Further down the line, doing large-scale studies on more people, with more data, will lead to the use of polygenic risk scores to help us rank our genetic potential for everything from getting cancer to being a genius. Can you imagine what it would be like for parents to pick new babies, GATTACA-style, to get the smartest kids? You don’t have to; it’s already happening.

Artificial Intelligence
Neil Jacobstein | Chair, Artificial Intelligence and Robotics, Singularity University

The convergence of exponentially improved computing power, the deep learning algorithm, and access to massive data resulted in a series of AI breakthroughs over the past decade. These included: vastly improved accuracy in identifying images, making self driving cars practical, beating several world champions in Go, and identifying gender, smoking status, and age from retinal fundus photographs.

Combined, these breakthroughs convinced researchers and investors that after 50+ years of research and development, AI was ready for prime-time applications. Now, virtually every field of human endeavor is being revolutionized by machine learning. We still have a long way to go to achieve human-level intelligence and beyond, but the pace of worldwide improvement is blistering.

Hod Lipson | Professor of Engineering and Data Science, Columbia University

The biggest moment in AI in the past decade (and in its entire history, in my humble opinion) was midnight, Pacific time, September 30, 2012: the moment when machines finally opened their eyes. It was the moment when deep learning took off, breaking stagnant decades of machine blindness, when AI couldn’t reliably tell apart even a cat from a dog. That seemingly trivial accomplishment—a task any one-year-old child can do—has had a ripple effect on AI applications from driverless cars to health diagnostics. And this is just the beginning of what is sure to be a Cambrian explosion of AI.

Neuroscience
Divya Chander | Chair, Neuroscience, Singularity University

If the 2000s were the decade of brain mapping, then the 2010s were the decade of brain writing. Optogenetics, a technique for precisely mapping and controlling neurons and neural circuits using genetically-directed light, saw incredible growth in the 2010s.

Also in the last 10 years, neuromodulation, or the ability to rewire the brain using both invasive and non-invasive interfaces and energy, has exploded in use and form. For instance, the Braingate consortium showed us how electrode arrays implanted into the motor cortex could be used by paralyzed people to use their thoughts to direct a robotic arm. These technologies, alone or in combination with robotics, exoskeletons, and flexible, implantable, electronics also make possible a future of human augmentation.

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