Tag Archives: proof

#435757 Robotic Animal Agility

Posted on September 19, 2019 by Android

An off-shore wind power platform, somewhere in the North Sea, on a freezing cold night, with howling winds and waves crashing against the impressive structure. An imperturbable ANYmal is quietly conducting its inspection.

ANYmal, a medium sized dog-like quadruped robot, walks down the stairs, lifts a “paw” to open doors or to call the elevator and trots along corridors. Darkness is no problem: it knows the place perfectly, having 3D-mapped it. Its laser sensors keep it informed about its precise path, location and potential obstacles. It conducts its inspection across several rooms. Its cameras zoom in on counters, recording the measurements displayed. Its thermal sensors record the temperature of machines and equipment and its ultrasound microphone checks for potential gas leaks. The robot also inspects lever positions as well as the correct positioning of regulatory fire extinguishers. As the electronic buzz of its engines resumes, it carries on working tirelessly.

After a little over two hours of inspection, the robot returns to its docking station for recharging. It will soon head back out to conduct its next solitary patrol. ANYmal played alongside Mulder and Scully in the “X-Files” TV series*, but it is in no way a Hollywood robot. It genuinely exists and surveillance missions are part of its very near future.

Off-shore oil platforms, the first test fields and probably the first actual application of ANYmal. ©ANYbotics

This quadruped robot was designed by ANYbotics, a spinoff of the Swiss Federal Institute of Technology in Zurich (ETH Zurich). Made of carbon fibre and aluminium, it weighs about thirty kilos. It is fully ruggedised, water- and dust-proof (IP-67). A kevlar belly protects its main body, carrying its powerful brain, batteries, network device, power management system and navigational systems.

ANYmal was designed for all types of terrain, including rubble, sand or snow. It has been field tested on industrial sites and is at ease with new obstacles to overcome (and it can even get up after a fall). Depending on its mission, its batteries last 2 to 4 hours.

On its jointed legs, protected by rubber pads, it can walk (at the speed of human steps), trot, climb, curl upon itself to crawl, carry a load or even jump and dance. It is the need to move on all surfaces that has driven its designers to choose a quadruped. “Biped robots are not easy to stabilise, especially on irregular terrain” explains Dr Péter Fankhauser, co-founder and chief business development officer of ANYbotics. “Wheeled or tracked robots can carry heavy loads, but they are bulky and less agile. Flying drones are highly mobile, but cannot carry load, handle objects or operate in bad weather conditions. We believe that quadrupeds combine the optimal characteristics, both in terms of mobility and versatility.”

What served as a source of inspiration for the team behind the project, the Robotic Systems Lab of the ETH Zurich, is a champion of agility on rugged terrain: the mountain goat. “We are of course still a long way” says Fankhauser. “However, it remains our objective on the longer term.

The first prototype, ALoF, was designed already back in 2009. It was still rather slow, very rigid and clumsy – more of a proof of concept than a robot ready for application. In 2012, StarlETH, fitted with spring joints, could hop, jump and climb. It was with this robot that the team started participating in 2014 in ARGOS, a full-scale challenge, launched by the Total oil group. The idea was to present a robot capable of inspecting an off-shore drilling station autonomously.

Up against dozens of competitors, the ETH Zurich team was the only team to enter the competition with such a quadrupedal robot. They didn’t win, but the multiple field tests were growing evermore convincing. Especially because, during the challenge, the team designed new joints with elastic actuators made in-house. These joints, inspired by tendons and muscles, are compact, sealed and include their own custom control electronics. They can regulate joint torque, position and impedance directly. Thanks to this innovation, the team could enter the same competition with a new version of its robot, ANYmal, fitted with three joints on each leg.

The ARGOS experience confirms the relevance of the selected means of locomotion. “Our robot is lighter, takes up less space on site and it is less noisy” says Fankhauser. “It also overcomes bigger obstacles than larger wheeled or tracked robots!” As ANYmal generated public interest and its transformation into a genuine product seemed more than possible, the startup ANYbotics was launched in 2016. It sold not only its robot, but also its revolutionary joints, called ANYdrive.

Today, ANYmal is not yet ready for sale to companies. However, ANYbotics has a growing number of partnerships with several industries, testing the robot for a few days or several weeks, for all types of tasks. Last October, for example, ANYmal navigated its way through the dark sewage system of the city of Zurich in order to test its capacity to help workers in similar difficult, repetitive and even dangerous tasks.

Why such an early interest among companies? “Because many companies want to integrate robots into their maintenance tasks” answers Fankhauser. “With ANYmal, they can actually evaluate its feasibility and plan their strategy. Eventually, both the architecture and the equipment of buildings could be rethought to be adapted to these maintenance robots”.

ANYmal requires ruggedised, sealed and extremely reliable interconnection solutions, such as LEMO. ©ANYbotics

Through field demonstrations and testing, ANYbotics can gather masses of information (up to 50,000 measurements are recorded every second during each test!) “It helps us to shape the product.” In due time, the startup will be ready to deliver a commercial product which really caters for companies’ needs.

Inspection and surveillance tasks on industrial sites are not the only applications considered. The startup is also thinking of agricultural inspections – with its onboard sensors, ANYmal is capable of mapping its environment, measuring bio mass and even taking soil samples. In the longer term, it could also be used for search and rescue operations. By the way, the robot can already be switched to “remote control” mode at any time and can be easily tele-operated. It is also capable of live audio and video transmission.

The transition from the prototype to the marketed product stage will involve a number of further developments. These include increasing ANYmal’s agility and speed, extending its capacity to map large-scale environments, improving safety, security, user handling and integrating the system with the customer’s data management software. It will also be necessary to enhance the robot’s reliability “so that it can work for days, weeks, or even months without human supervision.” All required certifications will have to be obtained. The locomotion system, which had triggered the whole business, is only one of a number of considerations of ANYbotics.

Designed for extreme environments, for ANYmal smoke is not a problem and it can walk in the snow, through rubble or in water. ©ANYbotics

The startup is not all alone. In fact, it has sold ANYmal robots to a dozen major universities who use them to develop their know-how in robotics. The startup has also founded ANYmal Research, a community including members such as Toyota Research Institute, the German Aerospace Center and the computer company Nvidia. Members have full access to ANYmal’s control software, simulations and documentation. Sharing has boosted both software and hardware ideas and developments (built on ROS, the open-source Robot Operating System). In particular, payload variations, providing for expandability and scalability. For instance, one of the universities uses a robotic arm which enables ANYmal to grasp or handle objects and open doors.

Among possible applications, ANYbotics mentions entertainment. It is not only about playing in more films or TV series, but rather about participating in various attractions (trade shows, museums, etc.). “ANYmal is so novel that it attracts a great amount of interest” confirms Fankhauser with a smile. “Whenever we present it somewhere, people gather around.”

Videos of these events show a fascinated and sometimes slightly fearful audience, when ANYmal gets too close to them. Is it fear of the “bad robot”? “This fear exists indeed and we are happy to be able to use ANYmal also to promote public awareness towards robotics and robots.” Reminiscent of a young dog, ANYmal is truly adapted for the purpose.

However, Péter Fankhauser softens the image of humans and sophisticated robots living together. “These coming years, robots will continue to work in the background, like they have for a long time in factories. Then, they will be used in public places in a selective and targeted way, for instance for dangerous missions. We will need to wait another ten years before animal-like robots, such as ANYmal will share our everyday lives!”

At the Consumer Electronics Show (CES) in Las Vegas in January, Continental, the German automotive manufacturing company, used robots to demonstrate a last-mile delivery. It showed ANYmal getting out of an autonomous vehicle with a parcel, climbing onto the front porch, lifting a paw to ring the doorbell, depositing the parcel before getting back into the vehicle. This futuristic image seems very close indeed.

*X-Files, season 11, episode 7, aired in February 2018 Continue reading →

Posted in Human Robots

#435731 Video Friday: NASA Is Sending This ...

Posted on September 18, 2019 by Android

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):

MARSS 2019 – July 1-5, 2019 – Helsinki, Finland
ICRES 2019 – July 29-30, 2019 – London, UK
DARPA SubT Tunnel Circuit – August 15-22, 2019 – Pittsburgh, PA, USA
Let us know if you have suggestions for next week, and enjoy today’s videos.

The big news today is that NASA is sending a robot to Saturn’s moon Titan. A flying robot. The Dragonfly mission will launch in 2026 and arrive in 2034, but you knew that already, because last January, we posted a detailed article about the concept from the Applied Physics Lab at Johns Hopkins University. And now it’s not a concept anymore, yay!

Again, read all the details plus an interview in 2018 article.

[ NASA ]

A robotic gripping arm that uses engineered bacteria to “taste” for a specific chemical has been developed by engineers at the University of California, Davis, and Carnegie Mellon University. The gripper is a proof-of-concept for biologically-based soft robotics.

The new device uses a biosensing module based on E. coli bacteria engineered to respond to the chemical IPTG by producing a fluorescent protein. The bacterial cells reside in wells with a flexible, porous membrane that allows chemicals to enter but keeps the cells inside. This biosensing module is built into the surface of a flexible gripper on a robotic arm, so the gripper can “taste” the environment through its fingers.

When IPTG crosses the membrane into the chamber, the cells fluoresce and electronic circuits inside the module detect the light. The electrical signal travels to the gripper’s control unit, which can decide whether to pick something up or release it.

[ UC Davis ]

The Toyota Research Institute (TRI) is taking on the hard problems in manipulation research toward making human-assist robots reliable and robust. Dr. Russ Tedrake, TRI Vice President of Robotics Research, explains how we are exploring the challenges and addressing the reliability gap by using a robot loading dishes in a dishwasher as an example task.

[ TRI ]

The Tactile Telerobot is the world’s first haptic telerobotic system that transmits realistic touch feedback to an operator located anywhere in the world. It is the product of joint collaboration between Shadow Robot Company, HaptX, and SynTouch. All Nippon Airways funded the project’s initial research and development.

What’s really unique about this is the HaptX tactile feedback system, which is something we’ve been following for several years now. It’s one of the most magical tech experiences I’ve ever had, and you can read about it here and here.

[ HaptX ]

Thanks Andrew!

I love how snake robots can emulate some of the fanciest moves of real snakes, and then also do bonkers things that real snakes never do.

[ Matsuno Lab ]

Here are a couple interesting videos from the Human-Robot Interaction Lab at Tufts.

A robot is instructed to perform an action and cannot do it due to lack of sensors. But when another robot is placed nearby, it can execute the instruction by tacitly tapping into the other robot’s mind and using that robot’s sensors for its own actions. Yes, it’s automatic, and yes, it’s the BORG!

Two Nao robots are instructed to perform a dance and are able to do it right after instruction. Moreover, they can switch roles immediately, and even a third different PR2 robot can perform the dance right away, demonstrating the ability of our DIARC architecture to learn quickly and share the knowledge with any type of robot running the architecture.

Compared to Nao, PR2 just sounds… depressed.

[ HRI Lab ]

This work explores the problem of robot tool construction – creating tools from parts available in the environment. We advance the state-of-the-art in robotic tool construction by introducing an approach that enables the robot to construct a wider range of tools with greater computational efficiency. Specifically, given an action that the robot wishes to accomplish and a set of building parts available to the robot, our approach reasons about the shape of the parts and potential ways of attaching them, generating a ranking of part combinations that the robot then uses to construct and test the target tool. We validate our approach on the construction of five tools using a physical 7-DOF robot arm.

[ RAIL Lab ] via [ RSS ]

We like Magazino’s approach to warehouse picking- constrain the problem to something you can reliably solve, like shoeboxes.

Magazino has announced a new pricing model for their robots. You pay 55k euros for the robot itself, and then after that, all you pay to keep the robot working is 6 cents per pick, so the robot is only costing you money for the work that it actually does.

[ Magazino ]

Thanks Florin!

Human-Robot Collaborations are happening across factories worldwide, yet very few are using it for smaller businesses, due to high costs or the difficulty of customization. Elephant Robotics, a new player from Shenzhen, the Silicon Valley of Asia, has set its sight on helping smaller businesses gain access to smart robotics. They created a Catbot (a collaborative robotic arm) that will offer high efficiency and flexibility to various industries.

The Catbot is set to help from education projects, photography, massaging, to being a personal barista or co-playing a table game. The customizations are endless. To increase the flexibility of usage, the Catbot is extremely easy to program from a high precision task up to covering hefty ground projects.

[ Elephant Robotics ]

Thanks Johnson!

Dronistics, an EPFL spin-off, has been testing out their enclosed delivery drone in the Dominican Republic through a partnership with WeRobotics.

[ WeRobotics ]

QTrobot is an expressive humanoid robot designed to help children with autism spectrum disorder and children with special educational needs in learning new skills. QTrobot uses simple and exaggerated facial expressions combined by interactive games and stories, to help children improve their emotional skills. QTrobot helps children to learn about and better understand the emotions and teach them strategies to handle their emotions more effectively.

[ LuxAI ]

Here’s a typical day in the life of a Tertill solar-powered autonomous weed-destroying robot.

$300, now shipping from Franklin Robotics.

[ Tertill ]

PAL Robotics is excited to announce a new TIAGo with two arms, TIAGo++! After carefully listening to the robotics community needs, we used TIAGo’s modularity to integrate two 7-DoF arms to our mobile manipulator. TIAGo++ can help you swiftly accomplish your research goals, opening endless possibilities in mobile manipulation.

[ PAL Robotics ]

Thanks Jack!

You’ve definitely already met the Cobalt security robot, but Toyota AI Ventures just threw a pile of money at them and would therefore like you to experience this re-introduction:

[ Cobalt Robotics ] via [ Toyota AI ]

ROSIE is a mobile manipulator kit from HEBI Robotics. And if you don’t like ROSIE, the modular nature of HEBI’s hardware means that you can take her apart and make something more interesting.

[ HEBI Robotics ]

Learn about Kawasaki Robotics’ second addition to their line of duAro dual-arm collaborative robots, duAro2. This model offers an extended vertical reach (550 mm) and an increased payload capacity (3 kg/arm).

[ Kawasaki Robotics ]

Drone Delivery Canada has partnered with Peel Region Paramedics to pilot its proprietary drone delivery platform to enable rapid first responder technology via drone with the goal to reduce response time and potentially save lives.

[ Drone Delivery Canada ]

In this week’s episode of Robots in Depth, Per speaks with Harri Ketamo, from Headai.

Harri Ketamo talks about AI and how he aims to mimic human decision making with algorithms. Harri has done a lot of AI for computer games to create opponents that are entertaining to play against. It is easy to develop a very bad or a very good opponent, but designing an opponent that behaves like a human, is entertaining to play against and that you can beat is quite hard. He talks about how AI in computer games is a very important story telling tool and an important part of making a game entertaining to play.

This work led him into other parts of the AI field. Harri thinks that we sometimes have a problem separating what is real from what is the type of story telling he knows from gaming AI. He calls for critical analysis of AI and says that data has to be used to verify AI decisions and results.

[ Robots in Depth ]

Thanks Per! Continue reading →

Posted in Human Robots

#435619 Video Friday: Watch This Robot Dog ...

Posted on September 13, 2019 by Android

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):

IEEE Africon 2019 – September 25-27, 2019 – Accra, Ghana
RoboBusiness 2019 – October 1-3, 2019 – Santa Clara, CA, USA
ISRR 2019 – October 6-10, 2019 – Hanoi, Vietnam
Ro-Man 2019 – October 14-18, 2019 – New Delhi, India
Humanoids 2019 – October 15-17, 2019 – Toronto, Canada
ARSO 2019 – October 31-1, 2019 – Beijing, China
ROSCon 2019 – October 31-1, 2019 – Macau
IROS 2019 – November 4-8, 2019 – Macau
Let us know if you have suggestions for next week, and enjoy today’s videos.

Team PLUTO (University of Pennsylvania, Ghost Robotics, and Exyn Technologies) put together this video giving us a robot’s-eye-view (or whatever they happen to be using for eyes) of the DARPA Subterranean Challenge tunnel circuits.

[ PLUTO ]

Zhifeng Huang has been improving his jet-stepping humanoid robot, which features new hardware and the ability to take larger and more complex steps.

This video reported the last progress of an ongoing project utilizing ducted-fan propulsion system to improve humanoid robot’s ability in stepping over large ditches. The landing point of the robot’s swing foot can be not only forward but also side direction. With keeping quasi-static balance, the robot was able to step over a ditch with 450mm in width (up to 97% of the robot’s leg’s length) in 3D stepping.

[ Paper ]

Thanks Zhifeng!

These underacuated hands from Matei Ciocarlie’s lab at Columbia are magically able to reconfigure themselves to grasp different object types with just one or two motors.

[ Paper ] via [ ROAM Lab ]

This is one reason we should pursue not “autonomous cars” but “fully autonomous cars” that never require humans to take over. We can’t be trusted.

During our early days as the Google self-driving car project, we invited some employees to test our vehicles on their commutes and weekend trips. What we were testing at the time was similar to the highway driver assist features that are now available on cars today, where the car takes over the boring parts of the driving, but if something outside its ability occurs, the driver has to take over immediately.

What we saw was that our testers put too much trust in that technology. They were doing things like texting, applying makeup, and even falling asleep that made it clear they would not be ready to take over driving if the vehicle asked them to. This is why we believe that nothing short of full autonomy will do.

[ Waymo ]

Buddy is a DIY and fetchingly minimalist social robot (of sorts) that will be coming to Kickstarter this month.

We have created a new arduino kit. His name is Buddy. He is a DIY social robot to serve as a replacement for Jibo, Cozmo, or any of the other bots that are no longer available. Fully 3D printed and supported he adds much more to our series of Arduino STEM robotics kits.

Buddy is able to look around and map his surroundings and react to changes within them. He can be surprised and he will always have a unique reaction to changes. The kit can be built very easily in less than an hour. It is even robust enough to take the abuse that kids can give it in a classroom.

[ Littlebots ]

The android Mindar, based on the Buddhist deity of mercy, preaches sermons at Kodaiji temple in Kyoto, and its human colleagues predict that with artificial intelligence it could one day acquire unlimited wisdom. Developed at a cost of almost $1 million (¥106 million) in a joint project between the Zen temple and robotics professor Hiroshi Ishiguro, the robot teaches about compassion and the dangers of desire, anger and ego.

[ Japan Times ]

I’m not sure whether it’s the sound or what, but this thing scares me for some reason.

[ BIRL ]

This gripper uses magnets as a sort of adjustable spring for dynamic stiffness control, which seems pretty clever.

[ Buffalo ]

What a package of medicine sees while being flown by drone from a hospital to a remote clinic in the Dominican Republic. The drone flew 11 km horizontally and 800 meters vertically, and I can’t even imagine what it would take to make that drive.

[ WeRobotics ]

My first ride in a fully autonomous car was at Stanford in 2009. I vividly remember getting in the back seat of a descendant of Junior, and watching the steering wheel turn by itself as the car executed a perfect parking maneuver. Ten years later, it’s still fun to watch other people have that experience.

[ Waymo ]

Flirtey, the pioneer of the commercial drone delivery industry, has unveiled the much-anticipated first video of its next-generation delivery drone, the Flirtey Eagle. The aircraft designer and manufacturer also unveiled the Flirtey Portal, a sophisticated take off and landing platform that enables scalable store-to-door operations; and an autonomous software platform that enables drones to deliver safely to homes.

[ Flirtey ]

EPFL scientists are developing new approaches for improved control of robotic hands – in particular for amputees – that combines individual finger control and automation for improved grasping and manipulation. This interdisciplinary proof-of-concept between neuroengineering and robotics was successfully tested on three amputees and seven healthy subjects.

[ EPFL ]

This video is a few years old, but we’ll take any excuse to watch the majestic sage-grouse be majestic in all their majesticness.

[ UC Davis ]

I like the idea of a game of soccer (or, football to you weirdos in the rest of the world) where the ball has a mind of its own.

[ Sphero ]

Looks like the whole delivery glider idea is really taking off! Or, you know, not taking off.

Weird that they didn’t show the landing, because it sure looked like it was going to plow into the side of the hill at full speed.

[ Yates ] via [ sUAS News ]

This video is from a 2018 paper, but it’s not like we ever get tired of seeing quadrupeds do stuff, right?

[ MIT ]

Founder and Head of Product, Ian Bernstein, and Head of Engineering, Morgan Bell, have been involved in the Misty project for years and they have learned a thing or two about building robots. Hear how and why Misty evolved into a robot development platform, learn what some of the earliest prototypes did (and why they didn’t work for what we envision), and take a deep dive into the technology decisions that form the Misty II platform.

[ Misty Robotics ]

Lex Fridman interviews Vijay Kumar on the Artifiical Intelligence Podcast.

[ AI Podcast ]

This week’s CMU RI Seminar is from Ross Knepper at Cornell, on Formalizing Teamwork in Human-Robot Interaction.

Robots out in the world today work for people but not with people. Before robots can work closely with ordinary people as part of a human-robot team in a home or office setting, robots need the ability to acquire a new mix of functional and social skills. Working with people requires a shared understanding of the task, capabilities, intentions, and background knowledge. For robots to act jointly as part of a team with people, they must engage in collaborative planning, which involves forming a consensus through an exchange of information about goals, capabilities, and partial plans. Often, much of this information is conveyed through implicit communication. In this talk, I formalize components of teamwork involving collaboration, communication, and representation. I illustrate how these concepts interact in the application of social navigation, which I argue is a first-class example of teamwork. In this setting, participants must avoid collision by legibly conveying intended passing sides via nonverbal cues like path shape. A topological representation using the braid groups enables the robot to reason about a small enumerable set of passing outcomes. I show how implicit communication of topological group plans achieves rapid covergence to a group consensus, and how a robot in the group can deliberately influence the ultimate outcome to maximize joint performance, yielding pedestrian comfort with the robot.

[ CMU RI ]

In this week’s episode of Robots in Depth, Per speaks with Julien Bourgeois about Claytronics, a project from Carnegie Mellon and Intel to develop “programmable matter.”

Julien started out as a computer scientist. He was always interested in robotics privately but then had the opportunity to get into micro robots when his lab was merged into the FEMTO-ST Institute. He later worked with Seth Copen Goldstein at Carnegie Mellon on the Claytronics project.

Julien shows an enlarged mock-up of the small robots that make up programmable matter, catoms, and speaks about how they are designed. Currently he is working on a unit that is one centimeter in diameter and he shows us the very small CPU that goes into that model.

[ Robots in Depth ] Continue reading →

Posted in Human Robots

#435593 AI at the Speed of Light

Posted on September 11, 2019 by Android

Neural networks shine for solving tough problems such as facial and voice recognition, but conventional electronic versions are limited in speed and hungry for power. In theory, optics could beat digital electronic computers in the matrix calculations used in neural networks. However, optics had been limited by their inability to do some complex calculations that had required electronics. Now new experiments show that all-optical neural networks can tackle those problems.

The key attraction of neural networks is their massive interconnections among processors, comparable to the complex interconnections among neurons in the brain. This lets them perform many operations simultaneously, like the human brain does when looking at faces or listening to speech, making them more efficient for facial and voice recognition than traditional electronic computers that execute one instruction at a time.

Today's electronic neural networks have reached eight million neurons, but their future use in artificial intelligence may be limited by their high power usage and limited parallelism in connections. Optical connections through lenses are inherently parallel. The lens in your eye simultaneously focuses light from across your field of view onto the retina in the back of your eye, where an array of light-detecting nerve cells detects the light. Each cell then relays the signal it receives to neurons in the brain that process the visual signals to show us an image.

Glass lenses process optical signals by focusing light, which performs a complex mathematical operation called a Fourier transform that preserves the information in the original scene but rearranges is completely. One use of Fourier transforms is converting time variations in signal intensity into a plot of the frequencies present in the signal. The military used this trick in the 1950s to convert raw radar return signals recorded by an aircraft in flight into a three-dimensional image of the landscape viewed by the plane. Today that conversion is done electronically, but the vacuum-tube computers of the 1950s were not up to the task.

Development of neural networks for artificial intelligence started with electronics, but their AI applications have been limited by their slow processing and need for extensive computing resources. Some researchers have developed hybrid neural networks, in which optics perform simple linear operations, but electronics perform more complex nonlinear calculations. Now two groups have demonstrated simple all-optical neural networks that do all processing with light.

In May, Wolfram Pernice of the Institute of Physics at the University of Münster in Germany and colleagues reported testing an all-optical “neuron” in which signals change target materials between liquid and solid states, an effect that has been used for optical data storage. They demonstrated nonlinear processing, and produced output pulses like those from organic neurons. They then produced an integrated photonic circuit that incorporated four optical neurons operating at different wavelengths, each of which connected to 15 optical synapses. The photonic circuit contained more than 140 components and could recognize simple optical patterns. The group wrote that their device is scalable, and that the technology promises “access to the high speed and high bandwidth inherent to optical systems, thus enabling the direct processing of optical telecommunication and visual data.”

Now a group at the Hong Kong University of Science and Technology reports in Optica that they have made an all-optical neural network based on a different process, electromagnetically induced transparency, in which incident light affects how atoms shift between quantum-mechanical energy levels. The process is nonlinear and can be triggered by very weak light signals, says Shengwang Du, a physics professor and coauthor of the paper.

In their demonstration, they illuminated rubidium-85 atoms cooled by lasers to about 10 microKelvin (10 microdegrees above absolute zero). Although the technique may seem unusually complex, Du said the system was the most accessible one in the lab that could produce the desired effects. “As a pure quantum atomic system [it] is ideal for this proof-of-principle experiment,” he says.

Next, they plan to scale up the demonstration using a hot atomic vapor center, which is less expensive, does not require time-consuming preparation of cold atoms, and can be integrated with photonic chips. Du says the major challenges are reducing cost of the nonlinear processing medium and increasing the scale of the all-optical neural network for more complex tasks.

“Their demonstration seems valid,” says Volker Sorger, an electrical engineer at George Washington University in Washington who was not involved in either demonstration. He says the all-optical approach is attractive because it offers very high parallelism, but the update rate is limited to about 100 hertz because of the liquid crystals used in their test, and he is not completely convinced their approach can be scaled error-free. Continue reading →

Posted in Human Robots

#435575 How an AI Startup Designed a Drug ...

Posted on September 9, 2019 by Android

Discovering a new drug can take decades, billions of dollars, and untold man hours from some of the smartest people on the planet. Now a startup says it’s taken a significant step towards speeding the process up using AI.

The typical drug discovery process involves carrying out physical tests on enormous libraries of molecules, and even with the help of robotics it’s an arduous process. The idea of sidestepping this by using computers to virtually screen for promising candidates has been around for decades. But progress has been underwhelming, and it’s still not a major part of commercial pipelines.

Recent advances in deep learning, however, have reignited hopes for the field, and major pharma companies have started tying up with AI-powered drug discovery startups. And now Insilico Medicine has used AI to design a molecule that effectively targets a protein involved in fibrosis—the formation of excess fibrous tissue—in mice in just 46 days.

The platform the company has developed combines two of the hottest sub-fields of AI: the generative adversarial networks, or GANs, which power deepfakes, and reinforcement learning, which is at the heart of the most impressive game-playing AI advances of recent years.

In a paper in Nature Biotechnology, the company’s researchers describe how they trained their model on all the molecules already known to target this protein as well as many other active molecules from various datasets. The model was then used to generate 30,000 candidate molecules.

Unlike most previous efforts, they went a step further and selected the most promising molecules for testing in the lab. The 30,000 candidates were whittled down to just 6 using more conventional drug discovery approaches and were then synthesized in the lab. They were put through increasingly stringent tests, but the leading candidate was found to be effective at targeting the desired protein and behaved as one would hope a drug would.

The authors are clear that the results are just a proof-of-concept, which company CEO Alex Zhavoronkov told Wired stemmed from a challenge set by a pharma partner to design a drug as quickly as possible. But they say they were able to carry out the process faster than traditional methods for a fraction of the cost.

There are some caveats. For a start, the protein being targeted is already very well known and multiple effective drugs exist for it. That gave the company a wealth of data to train their model on, something that isn’t the case for many of the diseases where we urgently need new drugs.

The company’s platform also only targets the very initial stages of the drug discovery process. The authors concede in their paper that the molecules would still take considerable optimization in the lab before they’d be true contenders for clinical trials.

“And that is where you will start to begin to commence to spend the vast piles of money that you will eventually go through in trying to get a drug to market,” writes Derek Lowe in his blog In The Pipeline. The part of the discovery process that the platform tackles represents a tiny fraction of the total cost of drug development, he says.

Nonetheless, the research is a definite advance for virtual screening technology and an important marker of the potential of AI for designing new medicines. Zhavoronkov also told Wired that this research was done more than a year ago, and they’ve since adapted the platform to go after harder drug targets with less data.

And with big pharma companies desperate to slash their ballooning development costs and find treatments for a host of intractable diseases, they can use all the help they can get.

Image Credit: freestocks.org / Unsplash Continue reading →

Posted in Human Robots