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#438006 Smellicopter Drone Uses Live Moth ...

Research into robotic sensing has, understandably I guess, been very human-centric. Most of us navigate and experience the world visually and in 3D, so robots tend to get covered with things like cameras and lidar. Touch is important to us, as is sound, so robots are getting pretty good with understanding tactile and auditory information, too. Smell, though? In most cases, smell doesn’t convey nearly as much information for us, so while it hasn’t exactly been ignored in robotics, it certainly isn’t the sensing modality of choice in most cases.

Part of the problem with smell sensing is that we just don’t have a good way of doing it, from a technical perspective. This has been a challenge for a long time, and it’s why we either bribe or trick animals like dogs, rats, vultures, and other animals to be our sensing systems for airborne chemicals. If only they’d do exactly what we wanted them to do all the time, this would be fine, but they don’t, so it’s not.

Until we get better at making chemical sensors, leveraging biology is the best we can do, and what would be ideal would be some sort of robot-animal hybrid cyborg thing. We’ve seen some attempts at remote controlled insects, but as it turns out, you can simplify things if you don’t use the entire insect, but instead just find a way to use its sensing system. Enter the Smellicopter.

There’s honestly not too much to say about the drone itself. It’s an open-source drone project called Crazyflie 2.0, with some additional off the shelf sensors for obstacle avoidance and stabilization. The interesting bits are a couple of passive fins that keep the drone pointed into the wind, and then the sensor, called an electroantennogram.

Image: UW

The drone’s sensor, called an electroantennogram, consists of a “single excised antenna” from a Manduca sexta hawkmoth and a custom signal processing circuit.

To make one of these sensors, you just, uh, “harvest” an antenna from a live hawkmoth. Obligingly, the moth antenna is hollow, meaning that you can stick electrodes up it. Whenever the olfactory neurons in the antenna (which is still technically alive even though it’s not attached to the moth anymore) encounter an odor that they’re looking for, they produce an electrical signal that the electrodes pick up. Plug the other ends of the electrodes into a voltage amplifier and filter, run it through an analog to digital converter, and you’ve got a chemical sensor that weighs just 1.5 gram and consumes only 2.7 mW of power. It’s significantly more sensitive than a conventional metal-oxide odor sensor, in a much smaller and more efficient form factor, making it ideal for drones.

To localize an odor, the Smellicopter uses a simple bioinspired approach called crosswind casting, which involves moving laterally left and right and then forward when an odor is detected. Here’s how it works:

The vehicle takes off to a height of 40 cm and then hovers for ten seconds to allow it time to orient upwind. The smellicopter starts casting left and right crosswind. When a volatile chemical is detected, the smellicopter will surge 25 cm upwind, and then resume casting. As long as the wind direction is fairly consistent, this strategy will bring the insect or robot increasingly closer to a singular source with each surge.

Since odors are airborne, they need a bit of a breeze to spread very far, and the Smellicopter won’t be able to detect them unless it’s downwind of the source. But, that’s just how odors work— even if you’re right next to the source, if the wind is blowing from you towards the source rather than the other way around, you might not catch a whiff of it.

Whenever the olfactory neurons in the antenna encounter an odor that they’re looking for, they produce an electrical signal that the electrodes pick up

There are a few other constraints to keep in mind with this sensor as well. First, rather than detecting something useful (like explosives), it’s going to detect the smells of pretty flowers, because moths like pretty flowers. Second, the antenna will literally go dead on you within a couple hours, since it only functions while its tissues are alive and metaphorically kicking. Interestingly, it may be possible to use CRISPR-based genetic modification to breed moths with antennae that do respond to useful smells, which would be a neat trick, and we asked the researchers—Melanie Anderson, a doctoral student of mechanical engineering at the University of Washington, in Seattle; Thomas Daniel, a UW professor of biology; and Sawyer Fuller, a UW assistant professor of mechanical engineering—about this, along with some other burning questions, via email.

IEEE Spectrum, asking the important questions first: So who came up with “Smellicopter”?

Melanie Anderson: Tom Daniel coined the term “Smellicopter”. Another runner up was “OdorRotor”!

In general, how much better are moths at odor localization than robots?

Melanie Anderson: Moths are excellent at odor detection and odor localization and need to be in order to find mates and food. Their antennae are much more sensitive and specialized than any portable man-made odor sensor. We can't ask the moths how exactly they search for odors so well, but being able to have the odor sensitivity of a moth on a flying platform is a big step in that direction.

Tom Daniel: Our best estimate is that they outperform robotic sensing by at least three orders of magnitude.

How does the localization behavior of the Smellicopter compare to that of a real moth?

Anderson: The cast-and-surge odor search strategy is a simplified version of what we believe the moth (and many other odor searching animals) are doing. It is a reactive strategy that relies on the knowledge that if you detect odor, you can assume that the source is somewhere up-wind of you. When you detect odor, you simply move upwind, and when you lose the odor signal you cast in a cross-wind direction until you regain the signal.

Can you elaborate on the potential for CRISPR to be able to engineer moths for the detection of specific chemicals?

Anderson: CRISPR is already currently being used to modify the odor detection pathways in moth species. It is one of our future efforts to specifically use this to make the antennae sensitive to other chemicals of interest, such as the chemical scent of explosives.

Sawyer Fuller: We think that one of the strengths of using a moth's antenna, in addition to its speed, is that it may provide a path to both high chemical specificity as well as high sensitivity. By expressing a preponderance of only one or a few chemosensors, we are anticipating that a moth antenna will give a strong response only to that chemical. There are several efforts underway in other research groups to make such specific, sensitive chemical detectors. Chemical sensing is an area where biology exceeds man-made systems in terms of efficiency, small size, and sensitivity. So that's why we think that the approach of trying to leverage biological machinery that already exists has some merit.

You mention that the antennae lifespan can be extended for a few days with ice- how feasible do you think this technology is outside of a research context?

Anderson: The antennae can be stored in tiny vials in a standard refrigerator or just with an ice pack to extend their life to about a week. Additionally, the process for attaching the antenna to the electrical circuit is a teachable skill. It is definitely feasible outside of a research context.

Considering the trajectory that sensor development is on, how long do you think that this biological sensor system will outperform conventional alternatives?

Anderson: It's hard to speak toward what will happen in the future, but currently, the moth antenna still stands out among any commercially-available portable sensors.

There have been some experiments with cybernetic insects; what are the advantages and disadvantages of your approach, as opposed to (say) putting some sort of tracking system on a live moth?

Daniel: I was part of a cyber insect team a number of years ago. The challenge of such research is that the animal has natural reactions to attempts to steer or control it.

Anderson: While moths are better at odor tracking than robots currently, the advantage of the drone platform is that we have control over it. We can tell it to constrain the search to a certain area, and return after it finishes searching.

What can you tell us about the health, happiness, and overall wellfare of the moths in your experiments?

Anderson: The moths are cold anesthetized before the antennae are removed. They are then frozen so that they can be used for teaching purposes or in other research efforts.

What are you working on next?

Daniel: The four big efforts are (1) CRISPR modification, (2) experiments aimed at improving the longevity of the antennal preparation, (3) improved measurements of antennal electrical responses to odors combined with machine learning to see if we can classify different odors, and (4) flight in outdoor environments.

Fuller: The moth's antenna sensor gives us a new ability to sense with a much shorter latency than was previously possible with similarly-sized sensors (e.g. semiconductor sensors). What exactly a robot agent should do to best take advantage of this is an open question. In particular, I think the speed may help it to zero in on plume sources in complex environments much more quickly. Think of places like indoor settings with flow down hallways that splits out at doorways, and in industrial settings festooned with pipes and equipment. We know that it is possible to search out and find odors in such scenarios, as anybody who has had to contend with an outbreak of fruit flies can attest. It is also known that these animals respond very quickly to sudden changes in odor that is present in such turbulent, patchy plumes. Since it is hard to reduce such plumes to a simple model, we think that machine learning may provide insights into how to best take advantage of the improved temporal plume information we now have available.

Tom Daniel also points out that the relative simplicity of this project (now that the UW researchers have it all figured out, that is) means that even high school students could potentially get involved in it, even if it’s on a ground robot rather than a drone. All the details are in the paper that was just published in Bioinspiration & Biomimetics. Continue reading

Posted in Human Robots

#437982 Superintelligent AI May Be Impossible to ...

It may be theoretically impossible for humans to control a superintelligent AI, a new study finds. Worse still, the research also quashes any hope for detecting such an unstoppable AI when it’s on the verge of being created.

Slightly less grim is the timetable. By at least one estimate, many decades lie ahead before any such existential computational reckoning could be in the cards for humanity.

Alongside news of AI besting humans at games such as chess, Go and Jeopardy have come fears that superintelligent machines smarter than the best human minds might one day run amok. “The question about whether superintelligence could be controlled if created is quite old,” says study lead author Manuel Alfonseca, a computer scientist at the Autonomous University of Madrid. “It goes back at least to Asimov’s First Law of Robotics, in the 1940s.”

The Three Laws of Robotics, first introduced in Isaac Asimov's 1942 short story “Runaround,” are as follows:

A robot may not injure a human being or, through inaction, allow a human being to come to harm.
A robot must obey the orders given it by human beings except where such orders would conflict with the First Law.
A robot must protect its own existence as long as such protection does not conflict with the First or Second Laws.

In 2014, philosopher Nick Bostrom, director of the Future of Humanity Institute at the University of Oxford, not only explored ways in which a superintelligent AI could destroy us but also investigated potential control strategies for such a machine—and the reasons they might not work.

Bostrom outlined two possible types of solutions of this “control problem.” One is to control what the AI can do, such as keeping it from connecting to the Internet, and the other is to control what it wants to do, such as teaching it rules and values so it would act in the best interests of humanity. The problem with the former is that Bostrom thought a supersmart machine could probably break free from any bonds we could make. With the latter, he essentially feared that humans might not be smart enough to train a superintelligent AI.

Now Alfonseca and his colleagues suggest it may be impossible to control a superintelligent AI, due to fundamental limits inherent to computing itself. They detailed their findings this month in the Journal of Artificial Intelligence Research.

The researchers suggested that any algorithm that sought to ensure a superintelligent AI cannot harm people had to first simulate the machine’s behavior to predict the potential consequences of its actions. This containment algorithm then would need to halt the supersmart machine if it might indeed do harm.

However, the scientists said it was impossible for any containment algorithm to simulate the AI’s behavior and predict with absolute certainty whether its actions might lead to harm. The algorithm could fail to correctly simulate the AI’s behavior or accurately predict the consequences of the AI’s actions and not recognize such failures.

“Asimov’s first law of robotics has been proved to be incomputable,” Alfonseca says, “and therefore unfeasible.”

We may not even know if we have created a superintelligent machine, the researchers say. This is a consequence of Rice’s theorem, which essentially states that one cannot in general figure anything out about what a computer program might output just by looking at the program, Alfonseca explains.

On the other hand, there’s no need to spruce up the guest room for our future robot overlords quite yet. Three important caveats to the research still leave plenty of uncertainty to the group’s predictions.

First, Alfonseca estimates AI’s moment of truth remains, he says, “At least two centuries in the future.”

Second, he says researchers do not know if so-called artificial general intelligence, also known as strong AI, is theoretically even feasible. “That is, a machine as intelligent as we are in an ample variety of fields,” Alfonseca explains.

Last, Alfonseca says, “We have not proved that superintelligences can never be controlled—only that they can’t always be controlled.”

Although it may not be possible to control a superintelligent artificial general intelligence, it should be possible to control a superintelligent narrow AI—one specialized for certain functions instead of being capable of a broad range of tasks like humans. “We already have superintelligences of this type,” Alfonseca says. “For instance, we have machines that can compute mathematics much faster than we can. This is [narrow] superintelligence, isn’t it?” Continue reading

Posted in Human Robots

#437964 How Explainable Artificial Intelligence ...

The field of artificial intelligence has created computers that can drive cars, synthesize chemical compounds, fold proteins, and detect high-energy particles at a superhuman level.

However, these AI algorithms cannot explain the thought processes behind their decisions. A computer that masters protein folding and also tells researchers more about the rules of biology is much more useful than a computer that folds proteins without explanation.

Therefore, AI researchers like me are now turning our efforts toward developing AI algorithms that can explain themselves in a manner that humans can understand. If we can do this, I believe that AI will be able to uncover and teach people new facts about the world that have not yet been discovered, leading to new innovations.

Learning From Experience
One field of AI, called reinforcement learning, studies how computers can learn from their own experiences. In reinforcement learning, an AI explores the world, receiving positive or negative feedback based on its actions.

This approach has led to algorithms that have independently learned to play chess at a superhuman level and prove mathematical theorems without any human guidance. In my work as an AI researcher, I use reinforcement learning to create AI algorithms that learn how to solve puzzles such as the Rubik’s Cube.

Through reinforcement learning, AIs are independently learning to solve problems that even humans struggle to figure out. This has got me and many other researchers thinking less about what AI can learn and more about what humans can learn from AI. A computer that can solve the Rubik’s Cube should be able to teach people how to solve it, too.

Peering Into the Black Box
Unfortunately, the minds of superhuman AIs are currently out of reach to us humans. AIs make terrible teachers and are what we in the computer science world call “black boxes.”

AI simply spits out solutions without giving reasons for its solutions. Computer scientists have been trying for decades to open this black box, and recent research has shown that many AI algorithms actually do think in ways that are similar to humans. For example, a computer trained to recognize animals will learn about different types of eyes and ears and will put this information together to correctly identify the animal.

The effort to open up the black box is called explainable AI. My research group at the AI Institute at the University of South Carolina is interested in developing explainable AI. To accomplish this, we work heavily with the Rubik’s Cube.

The Rubik’s Cube is basically a pathfinding problem: Find a path from point A—a scrambled Rubik’s Cube—to point B—a solved Rubik’s Cube. Other pathfinding problems include navigation, theorem proving and chemical synthesis.

My lab has set up a website where anyone can see how our AI algorithm solves the Rubik’s Cube; however, a person would be hard-pressed to learn how to solve the cube from this website. This is because the computer cannot tell you the logic behind its solutions.

Solutions to the Rubik’s Cube can be broken down into a few generalized steps—the first step, for example, could be to form a cross while the second step could be to put the corner pieces in place. While the Rubik’s Cube itself has over 10 to the 19th power possible combinations, a generalized step-by-step guide is very easy to remember and is applicable in many different scenarios.

Approaching a problem by breaking it down into steps is often the default manner in which people explain things to one another. The Rubik’s Cube naturally fits into this step-by-step framework, which gives us the opportunity to open the black box of our algorithm more easily. Creating AI algorithms that have this ability could allow people to collaborate with AI and break down a wide variety of complex problems into easy-to-understand steps.

A step-by-step refinement approach can make it easier for humans to understand why AIs do the things they do. Forest Agostinelli, CC BY-ND

Collaboration Leads to Innovation
Our process starts with using one’s own intuition to define a step-by-step plan thought to potentially solve a complex problem. The algorithm then looks at each individual step and gives feedback about which steps are possible, which are impossible and ways the plan could be improved. The human then refines the initial plan using the advice from the AI, and the process repeats until the problem is solved. The hope is that the person and the AI will eventually converge to a kind of mutual understanding.

Currently, our algorithm is able to consider a human plan for solving the Rubik’s Cube, suggest improvements to the plan, recognize plans that do not work and find alternatives that do. In doing so, it gives feedback that leads to a step-by-step plan for solving the Rubik’s Cube that a person can understand. Our team’s next step is to build an intuitive interface that will allow our algorithm to teach people how to solve the Rubik’s Cube. Our hope is to generalize this approach to a wide range of pathfinding problems.

People are intuitive in a way unmatched by any AI, but machines are far better in their computational power and algorithmic rigor. This back and forth between man and machine utilizes the strengths from both. I believe this type of collaboration will shed light on previously unsolved problems in everything from chemistry to mathematics, leading to new solutions, intuitions and innovations that may have, otherwise, been out of reach.

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Image Credit: Serg Antonov / Unsplash Continue reading

Posted in Human Robots

#437957 Meet Assembloids, Mini Human Brains With ...

It’s not often that a twitching, snowman-shaped blob of 3D human tissue makes someone’s day.

But when Dr. Sergiu Pasca at Stanford University witnessed the tiny movement, he knew his lab had achieved something special. You see, the blob was evolved from three lab-grown chunks of human tissue: a mini-brain, mini-spinal cord, and mini-muscle. Each individual component, churned to eerie humanoid perfection inside bubbling incubators, is already a work of scientific genius. But Pasca took the extra step, marinating the three components together inside a soup of nutrients.

The result was a bizarre, Lego-like human tissue that replicates the basic circuits behind how we decide to move. Without external prompting, when churned together like ice cream, the three ingredients physically linked up into a fully functional circuit. The 3D mini-brain, through the information highway formed by the artificial spinal cord, was able to make the lab-grown muscle twitch on demand.

In other words, if you think isolated mini-brains—known formally as brain organoids—floating in a jar is creepy, upgrade your nightmares. The next big thing in probing the brain is assembloids—free-floating brain circuits—that now combine brain tissue with an external output.

The end goal isn’t to freak people out. Rather, it’s to recapitulate our nervous system, from input to output, inside the controlled environment of a Petri dish. An autonomous, living brain-spinal cord-muscle entity is an invaluable model for figuring out how our own brains direct the intricate muscle movements that allow us stay upright, walk, or type on a keyboard.

It’s the nexus toward more dexterous brain-machine interfaces, and a model to understand when brain-muscle connections fail—as in devastating conditions like Lou Gehrig’s disease or Parkinson’s, where people slowly lose muscle control due to the gradual death of neurons that control muscle function. Assembloids are a sort of “mini-me,” a workaround for testing potential treatments on a simple “replica” of a person rather than directly on a human.

From Organoids to Assembloids
The miniature snippet of the human nervous system has been a long time in the making.

It all started in 2014, when Dr. Madeleine Lancaster, then a post-doc at Stanford, grew a shockingly intricate 3D replica of human brain tissue inside a whirling incubator. Revolutionarily different than standard cell cultures, which grind up brain tissue to reconstruct as a flat network of cells, Lancaster’s 3D brain organoids were incredibly sophisticated in their recapitulation of the human brain during development. Subsequent studies further solidified their similarity to the developing brain of a fetus—not just in terms of neuron types, but also their connections and structure.

With the finding that these mini-brains sparked with electrical activity, bioethicists increasingly raised red flags that the blobs of human brain tissue—no larger than the size of a pea at most—could harbor the potential to develop a sense of awareness if further matured and with external input and output.

Despite these concerns, brain organoids became an instant hit. Because they’re made of human tissue—often taken from actual human patients and converted into stem-cell-like states—organoids harbor the same genetic makeup as their donors. This makes it possible to study perplexing conditions such as autism, schizophrenia, or other brain disorders in a dish. What’s more, because they’re grown in the lab, it’s possible to genetically edit the mini-brains to test potential genetic culprits in the search for a cure.

Yet mini-brains had an Achilles’ heel: not all were made the same. Rather, depending on the region of the brain that was reverse engineered, the cells had to be persuaded by different cocktails of chemical soups and maintained in isolation. It was a stark contrast to our own developing brains, where regions are connected through highways of neural networks and work in tandem.

Pasca faced the problem head-on. Betting on the brain’s self-assembling capacity, his team hypothesized that it might be possible to grow different mini-brains, each reflecting a different brain region, and have them fuse together into a synchronized band of neuron circuits to process information. Last year, his idea paid off.

In one mind-blowing study, his team grew two separate portions of the brain into blobs, one representing the cortex, the other a deeper part of the brain known to control reward and movement, called the striatum. Shockingly, when put together, the two blobs of human brain tissue fused into a functional couple, automatically establishing neural highways that resulted in one of the most sophisticated recapitulations of a human brain. Pasca crowned this tissue engineering crème-de-la-crème “assembloids,” a portmanteau between “assemble” and “organoids.”

“We have demonstrated that regionalized brain spheroids can be put together to form fused structures called brain assembloids,” said Pasca at the time.” [They] can then be used to investigate developmental processes that were previously inaccessible.”

And if that’s possible for wiring up a lab-grown brain, why wouldn’t it work for larger neural circuits?

Assembloids, Assemble
The new study is the fruition of that idea.

The team started with human skin cells, scraped off of eight healthy people, and transformed them into a stem-cell-like state, called iPSCs. These cells have long been touted as the breakthrough for personalized medical treatment, before each reflects the genetic makeup of its original host.

Using two separate cocktails, the team then generated mini-brains and mini-spinal cords using these iPSCs. The two components were placed together “in close proximity” for three days inside a lab incubator, gently floating around each other in an intricate dance. To the team’s surprise, under the microscope using tracers that glow in the dark, they saw highways of branches extending from one organoid to the other like arms in a tight embrace. When stimulated with electricity, the links fired up, suggesting that the connections weren’t just for show—they’re capable of transmitting information.

“We made the parts,” said Pasca, “but they knew how to put themselves together.”

Then came the ménage à trois. Once the mini-brain and spinal cord formed their double-decker ice cream scoop, the team overlaid them onto a layer of muscle cells—cultured separately into a human-like muscular structure. The end result was a somewhat bizarre and silly-looking snowman, made of three oddly-shaped spherical balls.

Yet against all odds, the brain-spinal cord assembly reached out to the lab-grown muscle. Using a variety of tools, including measuring muscle contraction, the team found that this utterly Frankenstein-like snowman was able to make the muscle component contract—in a way similar to how our muscles twitch when needed.

“Skeletal muscle doesn’t usually contract on its own,” said Pasca. “Seeing that first twitch in a lab dish immediately after cortical stimulation is something that’s not soon forgotten.”

When tested for longevity, the contraption lasted for up to 10 weeks without any sort of breakdown. Far from a one-shot wonder, the isolated circuit worked even better the longer each component was connected.

Pasca isn’t the first to give mini-brains an output channel. Last year, the queen of brain organoids, Lancaster, chopped up mature mini-brains into slices, which were then linked to muscle tissue through a cultured spinal cord. Assembloids are a step up, showing that it’s possible to automatically sew multiple nerve-linked structures together, such as brain and muscle, sans slicing.

The question is what happens when these assembloids become more sophisticated, edging ever closer to the inherent wiring that powers our movements. Pasca’s study targets outputs, but what about inputs? Can we wire input channels, such as retinal cells, to mini-brains that have a rudimentary visual cortex to process those examples? Learning, after all, depends on examples of our world, which are processed inside computational circuits and delivered as outputs—potentially, muscle contractions.

To be clear, few would argue that today’s mini-brains are capable of any sort of consciousness or awareness. But as mini-brains get increasingly more sophisticated, at what point can we consider them a sort of AI, capable of computation or even something that mimics thought? We don’t yet have an answer—but the debates are on.

Image Credit: christitzeimaging.com / Shutterstock.com Continue reading

Posted in Human Robots

#437929 These Were Our Favorite Tech Stories ...

This time last year we were commemorating the end of a decade and looking ahead to the next one. Enter the year that felt like a decade all by itself: 2020. News written in January, the before-times, feels hopelessly out of touch with all that came after. Stories published in the early days of the pandemic are, for the most part, similarly naive.

The year’s news cycle was swift and brutal, ping-ponging from pandemic to extreme social and political tension, whipsawing economies, and natural disasters. Hope. Despair. Loneliness. Grief. Grit. More hope. Another lockdown. It’s been a hell of a year.

Though 2020 was dominated by big, hairy societal change, science and technology took significant steps forward. Researchers singularly focused on the pandemic and collaborated on solutions to a degree never before seen. New technologies converged to deliver vaccines in record time. The dark side of tech, from biased algorithms to the threat of omnipresent surveillance and corporate control of artificial intelligence, continued to rear its head.

Meanwhile, AI showed uncanny command of language, joined Reddit threads, and made inroads into some of science’s grandest challenges. Mars rockets flew for the first time, and a private company delivered astronauts to the International Space Station. Deprived of night life, concerts, and festivals, millions traveled to virtual worlds instead. Anonymous jet packs flew over LA. Mysterious monoliths appeared and disappeared worldwide.

It was all, you know, very 2020. For this year’s (in-no-way-all-encompassing) list of fascinating stories in tech and science, we tried to select those that weren’t totally dated by the news, but rose above it in some way. So, without further ado: This year’s picks.

How Science Beat the Virus
Ed Yong | The Atlantic
“Much like famous initiatives such as the Manhattan Project and the Apollo program, epidemics focus the energies of large groups of scientists. …But ‘nothing in history was even close to the level of pivoting that’s happening right now,’ Madhukar Pai of McGill University told me. … No other disease has been scrutinized so intensely, by so much combined intellect, in so brief a time.”

‘It Will Change Everything’: DeepMind’s AI Makes Gigantic Leap in Solving Protein Structures
Ewen Callaway | Nature
“In some cases, AlphaFold’s structure predictions were indistinguishable from those determined using ‘gold standard’ experimental methods such as X-ray crystallography and, in recent years, cryo-electron microscopy (cryo-EM). AlphaFold might not obviate the need for these laborious and expensive methods—yet—say scientists, but the AI will make it possible to study living things in new ways.”

OpenAI’s Latest Breakthrough Is Astonishingly Powerful, But Still Fighting Its Flaws
James Vincent | The Verge
“What makes GPT-3 amazing, they say, is not that it can tell you that the capital of Paraguay is Asunción (it is) or that 466 times 23.5 is 10,987 (it’s not), but that it’s capable of answering both questions and many more beside simply because it was trained on more data for longer than other programs. If there’s one thing we know that the world is creating more and more of, it’s data and computing power, which means GPT-3’s descendants are only going to get more clever.”

Artificial General Intelligence: Are We Close, and Does It Even Make Sense to Try?
Will Douglas Heaven | MIT Technology Review
“A machine that could think like a person has been the guiding vision of AI research since the earliest days—and remains its most divisive idea. …So why is AGI controversial? Why does it matter? And is it a reckless, misleading dream—or the ultimate goal?”

The Dark Side of Big Tech’s Funding for AI Research
Tom Simonite | Wired
“Timnit Gebru’s exit from Google is a powerful reminder of how thoroughly companies dominate the field, with the biggest computers and the most resources. …[Meredith] Whittaker of AI Now says properly probing the societal effects of AI is fundamentally incompatible with corporate labs. ‘That kind of research that looks at the power and politics of AI is and must be inherently adversarial to the firms that are profiting from this technology.’i”

We’re Not Prepared for the End of Moore’s Law
David Rotman | MIT Technology Review
“Quantum computing, carbon nanotube transistors, even spintronics, are enticing possibilities—but none are obvious replacements for the promise that Gordon Moore first saw in a simple integrated circuit. We need the research investments now to find out, though. Because one prediction is pretty much certain to come true: we’re always going to want more computing power.”

Inside the Race to Build the Best Quantum Computer on Earth
Gideon Lichfield | MIT Technology Review
“Regardless of whether you agree with Google’s position [on ‘quantum supremacy’] or IBM’s, the next goal is clear, Oliver says: to build a quantum computer that can do something useful. …The trouble is that it’s nearly impossible to predict what the first useful task will be, or how big a computer will be needed to perform it.”

The Secretive Company That Might End Privacy as We Know It
Kashmir Hill | The New York Times
“Searching someone by face could become as easy as Googling a name. Strangers would be able to listen in on sensitive conversations, take photos of the participants and know personal secrets. Someone walking down the street would be immediately identifiable—and his or her home address would be only a few clicks away. It would herald the end of public anonymity.”

Wrongfully Accused by an Algorithm
Kashmir Hill | The New York Times
“Mr. Williams knew that he had not committed the crime in question. What he could not have known, as he sat in the interrogation room, is that his case may be the first known account of an American being wrongfully arrested based on a flawed match from a facial recognition algorithm, according to experts on technology and the law.”

Predictive Policing Algorithms Are Racist. They Need to Be Dismantled.
Will Douglas Heaven | MIT Technology Review
“A number of studies have shown that these tools perpetuate systemic racism, and yet we still know very little about how they work, who is using them, and for what purpose. All of this needs to change before a proper reckoning can take pace. Luckily, the tide may be turning.”

The Panopticon Is Already Here
Ross Andersen | The Atlantic
“Artificial intelligence has applications in nearly every human domain, from the instant translation of spoken language to early viral-outbreak detection. But Xi [Jinping] also wants to use AI’s awesome analytical powers to push China to the cutting edge of surveillance. He wants to build an all-seeing digital system of social control, patrolled by precog algorithms that identify potential dissenters in real time.”

The Case For Cities That Aren’t Dystopian Surveillance States
Cory Doctorow | The Guardian
“Imagine a human-centered smart city that knows everything it can about things. It knows how many seats are free on every bus, it knows how busy every road is, it knows where there are short-hire bikes available and where there are potholes. …What it doesn’t know is anything about individuals in the city.”

The Modern World Has Finally Become Too Complex for Any of Us to Understand
Tim Maughan | OneZero
“One of the dominant themes of the last few years is that nothing makes sense. …I am here to tell you that the reason so much of the world seems incomprehensible is that it is incomprehensible. From social media to the global economy to supply chains, our lives rest precariously on systems that have become so complex, and we have yielded so much of it to technologies and autonomous actors that no one totally comprehends it all.”

The Conscience of Silicon Valley
Zach Baron | GQ
“What I really hoped to do, I said, was to talk about the future and how to live in it. This year feels like a crossroads; I do not need to explain what I mean by this. …I want to destroy my computer, through which I now work and ‘have drinks’ and stare at blurry simulations of my parents sometimes; I want to kneel down and pray to it like a god. I want someone—I want Jaron Lanier—to tell me where we’re going, and whether it’s going to be okay when we get there. Lanier just nodded. All right, then.”

Yes to Tech Optimism. And Pessimism.
Shira Ovide | The New York Times
“Technology is not something that exists in a bubble; it is a phenomenon that changes how we live or how our world works in ways that help and hurt. That calls for more humility and bridges across the optimism-pessimism divide from people who make technology, those of us who write about it, government officials and the public. We need to think on the bright side. And we need to consider the horribles.”

How Afrofuturism Can Help the World Mend
C. Brandon Ogbunu | Wired
“…[W. E. B. DuBois’] ‘The Comet’ helped lay the foundation for a paradigm known as Afrofuturism. A century later, as a comet carrying disease and social unrest has upended the world, Afrofuturism may be more relevant than ever. Its vision can help guide us out of the rubble, and help us to consider universes of better alternatives.”

Wikipedia Is the Last Best Place on the Internet
Richard Cooke | Wired
“More than an encyclopedia, Wikipedia has become a community, a library, a constitution, an experiment, a political manifesto—the closest thing there is to an online public square. It is one of the few remaining places that retains the faintly utopian glow of the early World Wide Web.”

Can Genetic Engineering Bring Back the American Chestnut?
Gabriel Popkin | The New York Times Magazine
“The geneticists’ research forces conservationists to confront, in a new and sometimes discomfiting way, the prospect that repairing the natural world does not necessarily mean returning to an unblemished Eden. It may instead mean embracing a role that we’ve already assumed: engineers of everything, including nature.”

At the Limits of Thought
David C. Krakauer | Aeon
“A schism is emerging in the scientific enterprise. On the one side is the human mind, the source of every story, theory, and explanation that our species holds dear. On the other stand the machines, whose algorithms possess astonishing predictive power but whose inner workings remain radically opaque to human observers.”

Is the Internet Conscious? If It Were, How Would We Know?
Meghan O’Gieblyn | Wired
“Does the internet behave like a creature with an internal life? Does it manifest the fruits of consciousness? There are certainly moments when it seems to. Google can anticipate what you’re going to type before you fully articulate it to yourself. Facebook ads can intuit that a woman is pregnant before she tells her family and friends. It is easy, in such moments, to conclude that you’re in the presence of another mind—though given the human tendency to anthropomorphize, we should be wary of quick conclusions.”

The Internet Is an Amnesia Machine
Simon Pitt | OneZero
“There was a time when I didn’t know what a Baby Yoda was. Then there was a time I couldn’t go online without reading about Baby Yoda. And now, Baby Yoda is a distant, shrugging memory. Soon there will be a generation of people who missed the whole thing and for whom Baby Yoda is as meaningless as it was for me a year ago.”

Digital Pregnancy Tests Are Almost as Powerful as the Original IBM PC
Tom Warren | The Verge
“Each test, which costs less than $5, includes a processor, RAM, a button cell battery, and a tiny LCD screen to display the result. …Foone speculates that this device is ‘probably faster at number crunching and basic I/O than the CPU used in the original IBM PC.’ IBM’s original PC was based on Intel’s 8088 microprocessor, an 8-bit chip that operated at 5Mhz. The difference here is that this is a pregnancy test you pee on and then throw away.”

The Party Goes on in Massive Online Worlds
Cecilia D’Anastasio | Wired
“We’re more stand-outside types than the types to cast a flashy glamour spell and chat up the nearest cat girl. But, hey, it’s Final Fantasy XIV online, and where my body sat in New York, the epicenter of America’s Covid-19 outbreak, there certainly weren’t any parties.”

The Facebook Groups Where People Pretend the Pandemic Isn’t Happening
Kaitlyn Tiffany | The Atlantic
“Losing track of a friend in a packed bar or screaming to be heard over a live band is not something that’s happening much in the real world at the moment, but it happens all the time in the 2,100-person Facebook group ‘a group where we all pretend we’re in the same venue.’ So does losing shoes and Juul pods, and shouting matches over which bands are the saddest, and therefore the greatest.”

Did You Fly a Jetpack Over Los Angeles This Weekend? Because the FBI Is Looking for You
Tom McKay | Gizmodo
“Did you fly a jetpack over Los Angeles at approximately 3,000 feet on Sunday? Some kind of tiny helicopter? Maybe a lawn chair with balloons tied to it? If the answer to any of the above questions is ‘yes,’ you should probably lay low for a while (by which I mean cool it on the single-occupant flying machine). That’s because passing airline pilots spotted you, and now it’s this whole thing with the FBI and the Federal Aviation Administration, both of which are investigating.”

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