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#437957 Meet Assembloids, Mini Human Brains With ...

It’s not often that a twitching, snowman-shaped blob of 3D human tissue makes someone’s day.

But when Dr. Sergiu Pasca at Stanford University witnessed the tiny movement, he knew his lab had achieved something special. You see, the blob was evolved from three lab-grown chunks of human tissue: a mini-brain, mini-spinal cord, and mini-muscle. Each individual component, churned to eerie humanoid perfection inside bubbling incubators, is already a work of scientific genius. But Pasca took the extra step, marinating the three components together inside a soup of nutrients.

The result was a bizarre, Lego-like human tissue that replicates the basic circuits behind how we decide to move. Without external prompting, when churned together like ice cream, the three ingredients physically linked up into a fully functional circuit. The 3D mini-brain, through the information highway formed by the artificial spinal cord, was able to make the lab-grown muscle twitch on demand.

In other words, if you think isolated mini-brains—known formally as brain organoids—floating in a jar is creepy, upgrade your nightmares. The next big thing in probing the brain is assembloids—free-floating brain circuits—that now combine brain tissue with an external output.

The end goal isn’t to freak people out. Rather, it’s to recapitulate our nervous system, from input to output, inside the controlled environment of a Petri dish. An autonomous, living brain-spinal cord-muscle entity is an invaluable model for figuring out how our own brains direct the intricate muscle movements that allow us stay upright, walk, or type on a keyboard.

It’s the nexus toward more dexterous brain-machine interfaces, and a model to understand when brain-muscle connections fail—as in devastating conditions like Lou Gehrig’s disease or Parkinson’s, where people slowly lose muscle control due to the gradual death of neurons that control muscle function. Assembloids are a sort of “mini-me,” a workaround for testing potential treatments on a simple “replica” of a person rather than directly on a human.

From Organoids to Assembloids
The miniature snippet of the human nervous system has been a long time in the making.

It all started in 2014, when Dr. Madeleine Lancaster, then a post-doc at Stanford, grew a shockingly intricate 3D replica of human brain tissue inside a whirling incubator. Revolutionarily different than standard cell cultures, which grind up brain tissue to reconstruct as a flat network of cells, Lancaster’s 3D brain organoids were incredibly sophisticated in their recapitulation of the human brain during development. Subsequent studies further solidified their similarity to the developing brain of a fetus—not just in terms of neuron types, but also their connections and structure.

With the finding that these mini-brains sparked with electrical activity, bioethicists increasingly raised red flags that the blobs of human brain tissue—no larger than the size of a pea at most—could harbor the potential to develop a sense of awareness if further matured and with external input and output.

Despite these concerns, brain organoids became an instant hit. Because they’re made of human tissue—often taken from actual human patients and converted into stem-cell-like states—organoids harbor the same genetic makeup as their donors. This makes it possible to study perplexing conditions such as autism, schizophrenia, or other brain disorders in a dish. What’s more, because they’re grown in the lab, it’s possible to genetically edit the mini-brains to test potential genetic culprits in the search for a cure.

Yet mini-brains had an Achilles’ heel: not all were made the same. Rather, depending on the region of the brain that was reverse engineered, the cells had to be persuaded by different cocktails of chemical soups and maintained in isolation. It was a stark contrast to our own developing brains, where regions are connected through highways of neural networks and work in tandem.

Pasca faced the problem head-on. Betting on the brain’s self-assembling capacity, his team hypothesized that it might be possible to grow different mini-brains, each reflecting a different brain region, and have them fuse together into a synchronized band of neuron circuits to process information. Last year, his idea paid off.

In one mind-blowing study, his team grew two separate portions of the brain into blobs, one representing the cortex, the other a deeper part of the brain known to control reward and movement, called the striatum. Shockingly, when put together, the two blobs of human brain tissue fused into a functional couple, automatically establishing neural highways that resulted in one of the most sophisticated recapitulations of a human brain. Pasca crowned this tissue engineering crème-de-la-crème “assembloids,” a portmanteau between “assemble” and “organoids.”

“We have demonstrated that regionalized brain spheroids can be put together to form fused structures called brain assembloids,” said Pasca at the time.” [They] can then be used to investigate developmental processes that were previously inaccessible.”

And if that’s possible for wiring up a lab-grown brain, why wouldn’t it work for larger neural circuits?

Assembloids, Assemble
The new study is the fruition of that idea.

The team started with human skin cells, scraped off of eight healthy people, and transformed them into a stem-cell-like state, called iPSCs. These cells have long been touted as the breakthrough for personalized medical treatment, before each reflects the genetic makeup of its original host.

Using two separate cocktails, the team then generated mini-brains and mini-spinal cords using these iPSCs. The two components were placed together “in close proximity” for three days inside a lab incubator, gently floating around each other in an intricate dance. To the team’s surprise, under the microscope using tracers that glow in the dark, they saw highways of branches extending from one organoid to the other like arms in a tight embrace. When stimulated with electricity, the links fired up, suggesting that the connections weren’t just for show—they’re capable of transmitting information.

“We made the parts,” said Pasca, “but they knew how to put themselves together.”

Then came the ménage à trois. Once the mini-brain and spinal cord formed their double-decker ice cream scoop, the team overlaid them onto a layer of muscle cells—cultured separately into a human-like muscular structure. The end result was a somewhat bizarre and silly-looking snowman, made of three oddly-shaped spherical balls.

Yet against all odds, the brain-spinal cord assembly reached out to the lab-grown muscle. Using a variety of tools, including measuring muscle contraction, the team found that this utterly Frankenstein-like snowman was able to make the muscle component contract—in a way similar to how our muscles twitch when needed.

“Skeletal muscle doesn’t usually contract on its own,” said Pasca. “Seeing that first twitch in a lab dish immediately after cortical stimulation is something that’s not soon forgotten.”

When tested for longevity, the contraption lasted for up to 10 weeks without any sort of breakdown. Far from a one-shot wonder, the isolated circuit worked even better the longer each component was connected.

Pasca isn’t the first to give mini-brains an output channel. Last year, the queen of brain organoids, Lancaster, chopped up mature mini-brains into slices, which were then linked to muscle tissue through a cultured spinal cord. Assembloids are a step up, showing that it’s possible to automatically sew multiple nerve-linked structures together, such as brain and muscle, sans slicing.

The question is what happens when these assembloids become more sophisticated, edging ever closer to the inherent wiring that powers our movements. Pasca’s study targets outputs, but what about inputs? Can we wire input channels, such as retinal cells, to mini-brains that have a rudimentary visual cortex to process those examples? Learning, after all, depends on examples of our world, which are processed inside computational circuits and delivered as outputs—potentially, muscle contractions.

To be clear, few would argue that today’s mini-brains are capable of any sort of consciousness or awareness. But as mini-brains get increasingly more sophisticated, at what point can we consider them a sort of AI, capable of computation or even something that mimics thought? We don’t yet have an answer—but the debates are on.

Image Credit: christitzeimaging.com / Shutterstock.com Continue reading

Posted in Human Robots

#437940 How Boston Dynamics Taught Its Robots to ...

A week ago, Boston Dynamics posted a video of Atlas, Spot, and Handle dancing to “Do You Love Me.” It was, according to the video description, a way “to celebrate the start of what we hope will be a happier year.” As of today the video has been viewed nearly 24 million times, and the popularity is no surprise, considering the compelling mix of technical prowess and creativity on display.

Strictly speaking, the stuff going on in the video isn’t groundbreaking, in the sense that we’re not seeing any of the robots demonstrate fundamentally new capabilities, but that shouldn’t take away from how impressive it is—you’re seeing state-of-the-art in humanoid robotics, quadrupedal robotics, and whatever-the-heck-Handle-is robotics.

What is unique about this video from Boston Dynamics is the artistic component. We know that Atlas can do some practical tasks, and we know it can do some gymnastics and some parkour, but dancing is certainly something new. To learn more about what it took to make these dancing robots happen (and it’s much more complicated than it might seem), we spoke with Aaron Saunders, Boston Dynamics’ VP of Engineering.

Saunders started at Boston Dynamics in 2003, meaning that he’s been a fundamental part of a huge number of Boston Dynamics’ robots, even the ones you may have forgotten about. Remember LittleDog, for example? A team of two designed and built that adorable little quadruped, and Saunders was one of them.

While he’s been part of the Atlas project since the beginning (and had a hand in just about everything else that Boston Dynamics works on), Saunders has spent the last few years leading the Atlas team specifically, and he was kind enough to answer our questions about their dancing robots.

IEEE Spectrum: What’s your sense of how the Internet has been reacting to the video?

Aaron Saunders: We have different expectations for the videos that we make; this one was definitely anchored in fun for us. The response on YouTube was record-setting for us: We received hundreds of emails and calls with people expressing their enthusiasm, and also sharing their ideas for what we should do next, what about this song, what about this dance move, so that was really fun. My favorite reaction was one that I got from my 94-year-old grandma, who watched the video on YouTube and then sent a message through the family asking if I’d taught the robot those sweet moves. I think this video connected with a broader audience, because it mixed the old-school music with new technology.

We haven’t seen Atlas move like this before—can you talk about how you made it happen?

We started by working with dancers and a choreographer to create an initial concept for the dance by composing and assembling a routine. One of the challenges, and probably the core challenge for Atlas in particular, was adjusting human dance moves so that they could be performed on the robot. To do that, we used simulation to rapidly iterate through movement concepts while soliciting feedback from the choreographer to reach behaviors that Atlas had the strength and speed to execute. It was very iterative—they would literally dance out what they wanted us to do, and the engineers would look at the screen and go “that would be easy” or “that would be hard” or “that scares me.” And then we’d have a discussion, try different things in simulation, and make adjustments to find a compatible set of moves that we could execute on Atlas.

Throughout the project, the time frame for creating those new dance moves got shorter and shorter as we built tools, and as an example, eventually we were able to use that toolchain to create one of Atlas’ ballet moves in just one day, the day before we filmed, and it worked. So it’s not hand-scripted or hand-coded, it’s about having a pipeline that lets you take a diverse set of motions, that you can describe through a variety of different inputs, and push them through and onto the robot.

Image: Boston Dynamics

Were there some things that were particularly difficult to translate from human dancers to Atlas? Or, things that Atlas could do better than humans?

Some of the spinning turns in the ballet parts took more iterations to get to work, because they were the furthest from leaping and running and some of the other things that we have more experience with, so they challenged both the machine and the software in new ways. We definitely learned not to underestimate how flexible and strong dancers are—when you take elite athletes and you try to do what they do but with a robot, it’s a hard problem. It’s humbling. Fundamentally, I don’t think that Atlas has the range of motion or power that these athletes do, although we continue developing our robots towards that, because we believe that in order to broadly deploy these kinds of robots commercially, and eventually in a home, we think they need to have this level of performance.

One thing that robots are really good at is doing something over and over again the exact same way. So once we dialed in what we wanted to do, the robots could just do it again and again as we played with different camera angles.

I can understand how you could use human dancers to help you put together a routine with Atlas, but how did that work with Spot, and particularly with Handle?

I think the people we worked with actually had a lot of talent for thinking about motion, and thinking about how to express themselves through motion. And our robots do motion really well—they’re dynamic, they’re exciting, they balance. So I think what we found was that the dancers connected with the way the robots moved, and then shaped that into a story, and it didn’t matter whether there were two legs or four legs. When you don’t necessarily have a template of animal motion or human behavior, you just have to think a little harder about how to go about doing something, and that’s true for more pragmatic commercial behaviors as well.

“We used simulation to rapidly iterate through movement concepts while soliciting feedback from the choreographer to reach behaviors that Atlas had the strength and speed to execute. It was very iterative—they would literally dance out what they wanted us to do, and the engineers would look at the screen and go ‘that would be easy’ or ‘that would be hard’ or ‘that scares me.’”
—Aaron Saunders, Boston Dynamics

How does the experience that you get teaching robots to dance, or to do gymnastics or parkour, inform your approach to robotics for commercial applications?

We think that the skills inherent in dance and parkour, like agility, balance, and perception, are fundamental to a wide variety of robot applications. Maybe more importantly, finding that intersection between building a new robot capability and having fun has been Boston Dynamics’ recipe for robotics—it’s a great way to advance.

One good example is how when you push limits by asking your robots to do these dynamic motions over a period of several days, you learn a lot about the robustness of your hardware. Spot, through its productization, has become incredibly robust, and required almost no maintenance—it could just dance all day long once you taught it to. And the reason it’s so robust today is because of all those lessons we learned from previous things that may have just seemed weird and fun. You’ve got to go into uncharted territory to even know what you don’t know.

Image: Boston Dynamics

It’s often hard to tell from watching videos like these how much time it took to make things work the way you wanted them to, and how representative they are of the actual capabilities of the robots. Can you talk about that?

Let me try to answer in the context of this video, but I think the same is true for all of the videos that we post. We work hard to make something, and once it works, it works. For Atlas, most of the robot control existed from our previous work, like the work that we’ve done on parkour, which sent us down a path of using model predictive controllers that account for dynamics and balance. We used those to run on the robot a set of dance steps that we’d designed offline with the dancers and choreographer. So, a lot of time, months, we spent thinking about the dance and composing the motions and iterating in simulation.

Dancing required a lot of strength and speed, so we even upgraded some of Atlas’ hardware to give it more power. Dance might be the highest power thing we’ve done to date—even though you might think parkour looks way more explosive, the amount of motion and speed that you have in dance is incredible. That also took a lot of time over the course of months; creating the capability in the machine to go along with the capability in the algorithms.

Once we had the final sequence that you see in the video, we only filmed for two days. Much of that time was spent figuring out how to move the camera through a scene with a bunch of robots in it to capture one continuous two-minute shot, and while we ran and filmed the dance routine multiple times, we could repeat it quite reliably. There was no cutting or splicing in that opening two-minute shot.

There were definitely some failures in the hardware that required maintenance, and our robots stumbled and fell down sometimes. These behaviors are not meant to be productized and to be a 100 percent reliable, but they’re definitely repeatable. We try to be honest with showing things that we can do, not a snippet of something that we did once. I think there’s an honesty required in saying that you’ve achieved something, and that’s definitely important for us.

You mentioned that Spot is now robust enough to dance all day. How about Atlas? If you kept on replacing its batteries, could it dance all day, too?

Atlas, as a machine, is still, you know… there are only a handful of them in the world, they’re complicated, and reliability was not a main focus. We would definitely break the robot from time to time. But the robustness of the hardware, in the context of what we were trying to do, was really great. And without that robustness, we wouldn’t have been able to make the video at all. I think Atlas is a little more like a helicopter, where there’s a higher ratio between the time you spend doing maintenance and the time you spend operating. Whereas with Spot, the expectation is that it’s more like a car, where you can run it for a long time before you have to touch it.

When you’re teaching Atlas to do new things, is it using any kind of machine learning? And if not, why not?

As a company, we’ve explored a lot of things, but Atlas is not using a learning controller right now. I expect that a day will come when we will. Atlas’ current dance performance uses a mixture of what we like to call reflexive control, which is a combination of reacting to forces, online and offline trajectory optimization, and model predictive control. We leverage these techniques because they’re a reliable way of unlocking really high performance stuff, and we understand how to wield these tools really well. We haven’t found the end of the road in terms of what we can do with them.

We plan on using learning to extend and build on the foundation of software and hardware that we’ve developed, but I think that we, along with the community, are still trying to figure out where the right places to apply these tools are. I think you’ll see that as part of our natural progression.

Image: Boston Dynamics

Much of Atlas’ dynamic motion comes from its lower body at the moment, but parkour makes use of upper body strength and agility as well, and we’ve seen some recent concept images showing Atlas doing vaults and pullups. Can you tell us more?

Humans and animals do amazing things using their legs, but they do even more amazing things when they use their whole bodies. I think parkour provides a fantastic framework that allows us to progress towards whole body mobility. Walking and running was just the start of that journey. We’re progressing through more complex dynamic behaviors like jumping and spinning, that’s what we’ve been working on for the last couple of years. And the next step is to explore how using arms to push and pull on the world could extend that agility.

One of the missions that I’ve given to the Atlas team is to start working on leveraging the arms as much as we leverage the legs to enhance and extend our mobility, and I’m really excited about what we’re going to be working on over the next couple of years, because it’s going to open up a lot more opportunities for us to do exciting stuff with Atlas.

What’s your perspective on hydraulic versus electric actuators for highly dynamic robots?

Across my career at Boston Dynamics, I’ve felt passionately connected to so many different types of technology, but I’ve settled into a place where I really don’t think this is an either-or conversation anymore. I think the selection of actuator technology really depends on the size of the robot that you’re building, what you want that robot to do, where you want it to go, and many other factors. Ultimately, it’s good to have both kinds of actuators in your toolbox, and I love having access to both—and we’ve used both with great success to make really impressive dynamic machines.

I think the only delineation between hydraulic and electric actuators that appears to be distinct for me is probably in scale. It’s really challenging to make tiny hydraulic things because the industry just doesn’t do a lot of that, and the reciprocal is that the industry also doesn’t tend to make massive electrical things. So, you may find that to be a natural division between these two technologies.

Besides what you’re working on at Boston Dynamics, what recent robotics research are you most excited about?

For us as a company, we really love to follow advances in sensing, computer vision, terrain perception, these are all things where the better they get, the more we can do. For me personally, one of the things I like to follow is manipulation research, and in particular manipulation research that advances our understanding of complex, friction-based interactions like sliding and pushing, or moving compliant things like ropes.

We’re seeing a shift from just pinching things, lifting them, moving them, and dropping them, to much more meaningful interactions with the environment. Research in that type of manipulation I think is going to unlock the potential for mobile manipulators, and I think it’s really going to open up the ability for robots to interact with the world in a rich way.

Is there anything else you’d like people to take away from this video?

For me personally, and I think it’s because I spend so much of my time immersed in robotics and have a deep appreciation for what a robot is and what its capabilities and limitations are, one of my strong desires is for more people to spend more time with robots. We see a lot of opinions and ideas from people looking at our videos on YouTube, and it seems to me that if more people had opportunities to think about and learn about and spend time with robots, that new level of understanding could help them imagine new ways in which robots could be useful in our daily lives. I think the possibilities are really exciting, and I just want more people to be able to take that journey. Continue reading

Posted in Human Robots

#437884 Hyundai Buys Boston Dynamics for Nearly ...

This morning just after 3 a.m. ET, Boston Dynamics sent out a media release confirming that Hyundai Motor Group has acquired a controlling interest in the company that values Boston Dynamics at US $1.1 billion:

Under the agreement, Hyundai Motor Group will hold an approximately 80 percent stake in Boston Dynamics and SoftBank, through one of its affiliates, will retain an approximately 20 percent stake in Boston Dynamics after the closing of the transaction.

The release is very long, but does have some interesting bits—we’ll go through them, and talk about what this might mean for both Boston Dynamics and Hyundai.

We’ve asked Boston Dynamics for comment, but they’ve been unusually quiet for the last few days (I wonder why!). So at this point just keep in mind that the only things we know for sure are the ones in the release. If (when?) we hear anything from either Boston Dynamics or Hyundai, we’ll update this post.

The first thing to be clear on is that the acquisition is split between Hyundai Motor Group’s affiliates, including Hyundai Motor, Hyundai Mobis, and Hyundai Glovis. Hyundai Motor makes cars, Hyundai Mobis makes car parts and seems to be doing some autonomous stuff as well, and Hyundai Glovis does logistics. There are many other groups that share the Hyundai name, but they’re separate entities, at least on paper. For example, there’s a Hyundai Robotics, but that’s part of Hyundai Heavy Industries, a different company than Hyundai Motor Group. But for this article, when we say “Hyundai,” we’re talking about Hyundai Motor Group.

What’s in it for Hyundai?
Let’s get into the press release, which is filled with press release-y terms like “synergies” and “working together”—you can view the whole thing here—but still has some parts that convey useful info.

By establishing a leading presence in the field of robotics, the acquisition will mark another major step for Hyundai Motor Group toward its strategic transformation into a Smart Mobility Solution Provider. To propel this transformation, Hyundai Motor Group has invested substantially in development of future technologies, including in fields such as autonomous driving technology, connectivity, eco-friendly vehicles, smart factories, advanced materials, artificial intelligence (AI), and robots.

If Hyundai wants to be a “Smart Mobility Solution Provider” with a focus on vehicles, it really seems like there’s a whole bunch of other ways they could have spent most of a billion dollars that would get them there quicker. Will Boston Dynamics’ expertise help them develop autonomous driving technology? Sure, I guess, but why not just buy an autonomous car startup instead? Boston Dynamics is more about “robots,” which happens to be dead last on the list above.

There was some speculation a couple of weeks ago that Hyundai was going to try and leverage Boston Dynamics to make a real version of this hybrid wheeled/legged concept car, so if that’s what Hyundai means by “Smart Mobility Solution Provider,” then I suppose the Boston Dynamics acquisition makes more sense. Still, I think that’s unlikely, because it’s just a concept car, after all.

In addition to “smart mobility,” which seems like a longer-term goal for Hyundai, the company also mentions other, more immediate benefits from the acquisition:

Advanced robotics offer opportunities for rapid growth with the potential to positively impact society in multiple ways. Boston Dynamics is the established leader in developing agile, mobile robots that have been successfully integrated into various business operations. The deal is also expected to allow Hyundai Motor Group and Boston Dynamics to leverage each other’s respective strengths in manufacturing, logistics, construction and automation.

“Successfully integrated” might be a little optimistic here. They’re talking about Spot, of course, but I think the best you could say at this point is that Spot is in the middle of some promising pilot projects. Whether it’ll be successfully integrated in the sense that it’ll have long-term commercial usefulness and value remains to be seen. I’m optimistic about this as well, but Spot is definitely not there yet.

What does probably hold a lot of value for Hyundai is getting Spot, Pick, and perhaps even Handle into that “manufacturing, logistics, construction” stuff. This is the bread and butter for robots right now, and Boston Dynamics has plenty of valuable technology to offer in those spaces.

Photo: Bob O’Connor

Boston Dynamics is selling Spot for $74,500, shipping included.

Betting on Spot and Pick
With Boston Dynamics founder Marc Raibert’s transition to Chairman of the company, the CEO position is now occupied by Robert Playter, the long-time VP of engineering and more recently COO at Boston Dynamics. Here’s his statement from the release:

“Boston Dynamics’ commercial business has grown rapidly as we’ve brought to market the first robot that can automate repetitive and dangerous tasks in workplaces designed for human-level mobility. We and Hyundai share a view of the transformational power of mobility and look forward to working together to accelerate our plans to enable the world with cutting edge automation, and to continue to solve the world’s hardest robotics challenges for our customers.”

Whether Spot is in fact “the first robot that can automate repetitive and dangerous tasks in workplaces designed for human-level mobility” on the market is perhaps something that could be argued against, although I won’t. Whether or not it was the first robot that can do these kinds of things, it’s definitely not the only robot that do these kinds of things, and going forward, it’s going to be increasingly challenging for Spot to maintain its uniqueness.

For a long time, Boston Dynamics totally owned the quadruped space. Now, they’re one company among many—ANYbotics and Unitree are just two examples of other quadrupeds that are being successfully commercialized. Spot is certainly very capable and easy to use, and we shouldn’t underestimate the effort required to create a robot as complex as Spot that can be commercially used and supported. But it’s not clear how long they’ll maintain that advantage, with much more affordable platforms coming out of Asia, and other companies offering some unique new capabilities.

Photo: Boston Dynamics

Boston Dynamics’ Handle is an all-electric robot featuring a leg-wheel hybrid mobility system, a manipulator arm with a vacuum gripper, and a counterbalancing tail.

Boston Dynamics’ picking system, which stemmed from their 2019 acquisition of Kinema Systems, faces the same kinds of challenges—it’s very good, but it’s not totally unique.

Boston Dynamics produces highly capable mobile robots with advanced mobility, dexterity and intelligence, enabling automation in difficult, dangerous, or unstructured environments. The company launched sales of its first commercial robot, Spot in June of 2020 and has since sold hundreds of robots in a variety of industries, such as power utilities, construction, manufacturing, oil and gas, and mining. Boston Dynamics plans to expand the Spot product line early next year with an enterprise version of the robot with greater levels of autonomy and remote inspection capabilities, and the release of a robotic arm, which will be a breakthrough in mobile manipulation.

Boston Dynamics is also entering the logistics automation market with the industry leading Pick, a computer vision-based depalletizing solution, and will introduce a mobile robot for warehouses in 2021.

Huh. We’ll be trying to figure out what “greater levels of autonomy” means, as well as whether the “mobile robot for warehouses” is Handle, or something more like an autonomous mobile robot (AMR) platform. I’d honestly be surprised if Handle was ready for work outside of Boston Dynamics next year, and it’s hard to imagine how Boston Dynamics could leverage their expertise into the AMR space with something that wouldn’t just seem… Dull, compared to what they usually do. I hope to be surprised, though!

A new deep-pocketed benefactor

Hyundai Motor Group’s decision to acquire Boston Dynamics is based on its growth potential and wide range of capabilities.

“Wide range of capabilities” we get, but that other phrase, “growth potential,” has a heck of a lot wrapped up in it. At the moment, Boston Dynamics is nowhere near profitable, as far as we know. SoftBank acquired Boston Dynamics in 2017 for between one hundred and two hundred million, and over the last three years they’ve poured hundreds of millions more into Boston Dynamics.

Hyundai’s 80 percent stake just means that they’ll need to take over the majority of that support, and perhaps even increase it if Boston Dynamics’ growth is one of their primary goals. Hyundai can’t have a reasonable expectation that Boston Dynamics will be profitable any time soon; they’re selling Spots now, but it’s an open question whether Spot will manage to find a scalable niche in which it’ll be useful in the sort of volume that will make it a sustainable commercial success. And even if it does become a success, it seems unlikely that Spot by itself will make a significant dent in Boston Dynamics’ burn rate anytime soon. Boston Dynamics will have more products of course, but it’s going to take a while, and Hyundai will need to support them in the interim.

Depending on whether Hyundai views Boston Dynamics as a company that does research or a company that makes robots that are useful and profitable, it may be difficult for Boston Dynamics to justify the cost to develop the
next Atlas, when the
current one still seems so far from commercialization

It’s become clear that to sustain itself, Boston Dynamics needs a benefactor with very deep pockets and a long time horizon. Initially, Boston Dynamics’ business model (or whatever you want to call it) was to do bespoke projects for defense-ish folks like DARPA, but from what we understand Boston Dynamics stopped that sort of work after Google acquired them back in 2013. From one perspective, that government funding did exactly what it was supposed to do, which was to fund the development of legged robots through low TRLs (technology readiness levels) to the point where they could start to explore commercialization.

The question now, though, is whether Hyundai is willing to let Boston Dynamics undertake the kinds of low-TRL, high-risk projects that led from BigDog to LS3 to Spot, and from PETMAN to DRC Atlas to the current Atlas. So will Hyundai be cool about the whole thing and be the sort of benefactor that’s willing to give Boston Dynamics the resources that they need to keep doing what they’re doing, without having to answer too many awkward questions about things like practicality and profitability? Hyundai can certainly afford to do this, but so could SoftBank, and Google—the question is whether Hyundai will want to, over the length of time that’s required for the development of the kind of ultra-sophisticated robotics hardware that Boston Dynamics specializes in.

To put it another way: Depending whether Hyundai’s perspective on Boston Dynamics is as a company that does research or a company that makes robots that are useful and profitable, it may be difficult for Boston Dynamics to justify the cost to develop the next Atlas, when the current one still seems so far from commercialization.

Google, SoftBank, now Hyundai

Boston Dynamics possesses multiple key technologies for high-performance robots equipped with perception, navigation, and intelligence.

Hyundai Motor Group’s AI and Human Robot Interaction (HRI) expertise is highly synergistic with Boston Dynamics’s 3D vision, manipulation, and bipedal/quadruped expertise.

As it turns out, Hyundai Motors does have its own robotics lab, called Hyundai Motors Robotics Lab. Their website is not all that great, but here’s a video from last year:

I’m not entirely clear on what Hyundai means when they use the word “synergistic” when they talk about their robotics lab and Boston Dynamics, but it’s a little bit concerning. Usually, when a big company buys a little company that specializes in something that the big company is interested in, the idea is that the little company, to some extent, will be absorbed into the big company to give them some expertise in that area. Historically, however, Boston Dynamics has been highly resistant to this, maintaining its post-acquisition independence and appearing to be very reluctant to do anything besides what it wants to do, at whatever pace it wants to do it, and as by itself as possible.

From what we understand, Boston Dynamics didn’t integrate particularly well with Google’s robotics push in 2013, and we haven’t seen much evidence that SoftBank’s experience was much different. The most direct benefit to SoftBank (or at least the most visible one) was the addition of a fleet of Spot robots to the SoftBank Hawks baseball team cheerleading squad, along with a single (that we know about) choreographed gymnastics routine from an Atlas robot that was only shown on video.

And honestly, if you were a big manufacturing company with a bunch of money and you wanted to build up your own robotics program quickly, you’d probably have much better luck picking up some smaller robotics companies who were a bit less individualistic and would probably be more amenable to integration and would cost way less than a billion dollars-ish. And if integration is ultimately Hyundai’s goal, we’ll be very sad, because it’ll likely signal the end of Boston Dynamics doing the unfettered crazy stuff that we’ve grown to love.

Photo: Bob O’Connor

Possibly the most agile humanoid robot ever built, Atlas can run, climb, jump over obstacles, and even get up after a fall.

Boston Dynamics contemplates its future

The release ends by saying that the transaction is “subject to regulatory approvals and other customary closing conditions” and “is expected to close by June of 2021.” Again, you can read the whole thing here.

My initial reaction is that, despite the “synergies” described by Hyundai, it’s certainly not immediately obvious why the company wants to own 80 percent of Boston Dynamics. I’d also like a better understanding of how they arrived at the $1.1 billion valuation. I’m not saying this because I don’t believe in what Boston Dynamics is doing or in the inherent value of the company, because I absolutely do, albeit perhaps in a slightly less tangible sense. But when you start tossing around numbers like these, a big pile of expectations inevitably comes along with them. I hope that Boston Dynamics is unique enough that the kinds of rules that normally apply to robotics companies (or companies in general) can be set aside, at least somewhat, but I also worry that what made Boston Dynamics great was the explicit funding for the kinds of radical ideas that eventually resulted in robots like Atlas and Spot.

Can Hyundai continue giving Boston Dynamics the support and freedom that they need to keep doing the kinds of things that have made them legendary? I certainly hope so. Continue reading

Posted in Human Robots

#437882 Video Friday: MIT Mini-Cheetah Robots ...

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

ICCR 2020 – December 26-29, 2020 – [Online Conference]
HRI 2021 – March 8-11, 2021 – [Online Conference]
RoboSoft 2021 – April 12-16, 2021 – [Online Conference]
Let us know if you have suggestions for next week, and enjoy today's videos.

What a lovely Christmas video from Norlab.

[ Norlab ]

Thanks Francois!

MIT Mini-Cheetahs are looking for a new home. Our new cheetah cubs, born at NAVER LABS, are for the MIT Mini-Cheetah workshop. MIT professor Sangbae Kim and his research team are supporting joint research by distributing Mini-Cheetahs to researchers all around the world.

[ NAVER Labs ]

For several years, NVIDIA’s research teams have been working to leverage GPU technology to accelerate reinforcement learning (RL). As a result of this promising research, NVIDIA is pleased to announce a preview release of Isaac Gym – NVIDIA’s physics simulation environment for reinforcement learning research. RL-based training is now more accessible as tasks that once required thousands of CPU cores can now instead be trained using a single GPU.

[ NVIDIA ]

At SINTEF in Norway, they're working on ways of using robots to keep tabs on giant floating cages of tasty fish:

One of the tricky things about operating robots in an environment like this is localization, so SINTEF is working on a solution that uses beacons:

While that video shows a lot of simulation (because otherwise there are tons of fish in the way), we're told that the autonomous navigation has been successfully demonstrated with an ROV in “a full scale fish farm with up to 200.000 salmon swimming around the robot.”

[ SINTEF ]

Thanks Eleni!

We’ve been getting ready for the snow in the most BG way possible. Wishing all of you a happy and healthy holiday season.

[ Berkshire Grey ]

ANYbotics doesn’t care what time of the year it is, so Happy Easter!

And here's a little bit about why ANYmal C looks the way it does.

[ ANYbotics ]

Robert “Buz” Chmielewski is using two modular prosthetic limbs developed by APL to feed himself dessert. Smart software puts his utensils in roughly the right spot, and then Buz uses his brain signals to cut the food with knife and fork. Once he is done cutting, the software then brings the food near his mouth, where he again uses brain signals to bring the food the last several inches to his mouth so that he can eat it.

[ JHUAPL ]

Introducing VESPER: a new military-grade small drone that is designed, sourced and built in the United States. Vesper offers a 50-minutes flight time, with speeds up to 45 mph (72 kph) and a total flight range of 25 miles (45 km). The magnetic snap-together architecture enables extremely fast transitions: the battery, props and rotor set can each be swapped in <5 seconds.

[ Vantage Robotics ]

In this video, a multi-material robot simulator is used to design a shape-changing robot, which is then transferred to physical hardware. The simulated and real robots can use shape change to switch between rolling gaits and inchworm gaits, to locomote in multiple environments.

[ Yale Faboratory ]

Get a preview of the cave environments that are being used to inspire the Final Event competition course of the DARPA Subterranean Challenge. In the Final Event, teams will deploy their robots to rapidly map, navigate, and search in competition courses that combine elements of man-made tunnel systems, urban underground, and natural cave networks!

The reason to pay attention this particular video is that it gives us some idea of what DARPA means when they say "cave."

[ SubT ]

MQ25 takes another step toward unmanned aerial refueling for the U.S. Navy. The MQ-25 test asset has flown for the first time with an aerial refueling pod containing the hose and basket that will make it an aerial refueler.

[ Boeing ]

We present a unified model-based and data-driven approach for quadrupedal planning and control to achieve dynamic locomotion over uneven terrain. We utilize on-board proprioceptive and exteroceptive feedback to map sensory information and desired base velocity commands into footstep plans using a reinforcement learning (RL) policy trained in simulation over a wide range of procedurally generated terrains.

[ DRS ]

The video shows the results of the German research project RoPHa. Within the project, the partners developed technologies for two application scenarios with the service robot Care-O-bot 4 in order to support people in need of help when eating.

[ RoPHa Project ]

Thanks Jenny!

This looks like it would be fun, if you are a crazy person.

[ Team BlackSheep ]

Robot accuracy is the limiting factor in many industrial applications. Manufacturers often only specify the pose repeatability values of their robotic systems. Fraunhofer IPA has set up a testing environment for automated measuring of accuracy performance criteria of industrial robots. Following the procedures defined in norm ISO 9283 allows generating reliable and repeatable results. They can be the basis for targeted measures increasing the robotic system’s accuracy.

[ Fraunhofer ]

Thanks Jenny!

The IEEE Women in Engineering – Robotics and Automation Society (WIE-RAS) hosted an online panel on best practices for teaching robotics. The diverse panel boasts experts in robotics education from a variety of disciplines, institutions, and areas of expertise.

[ IEEE RAS ]

Northwestern researchers have developed a first-of-its-kind soft, aquatic robot that is powered by light and rotating magnetic fields. These life-like robotic materials could someday be used as "smart" microscopic systems for production of fuels and drugs, environmental cleanup or transformative medical procedures.

[ Northwestern ]

Tech United Eindhoven's soccer robots now have eight wheels instead of four wheels, making them tweleve times better, if my math is right.

[ TU Eindhoven ] Continue reading

Posted in Human Robots

#437872 AlphaFold Proves That AI Can Crack ...

Any successful implementation of artificial intelligence hinges on asking the right questions in the right way. That’s what the British AI company DeepMind (a subsidiary of Alphabet) accomplished when it used its neural network to tackle one of biology’s grand challenges, the protein-folding problem. Its neural net, known as AlphaFold, was able to predict the 3D structures of proteins based on their amino acid sequences with unprecedented accuracy.

AlphaFold’s predictions at the 14th Critical Assessment of protein Structure Prediction (CASP14) were accurate to within an atom’s width for most of the proteins. The competition consisted of blindly predicting the structure of proteins that have only recently been experimentally determined—with some still awaiting determination.

Called the building blocks of life, proteins consist of 20 different amino acids in various combinations and sequences. A protein's biological function is tied to its 3D structure. Therefore, knowledge of the final folded shape is essential to understanding how a specific protein works—such as how they interact with other biomolecules, how they may be controlled or modified, and so on. “Being able to predict structure from sequence is the first real step towards protein design,” says Janet M. Thornton, director emeritus of the European Bioinformatics Institute. It also has enormous benefits in understanding disease-causing pathogens. For instance, at the moment only about 18 of the 26 proteins in the SARS-CoV-2 virus are known.

Predicting a protein’s 3D structure is a computational nightmare. In 1969 Cyrus Levinthal estimated that there are 10300 possible conformational combinations for a single protein, which would take longer than the age of the known universe to evaluate by brute force calculation. AlphaFold can do it in a few days.

As scientific breakthroughs go, AlphaFold’s discovery is right up there with the likes of James Watson and Francis Crick’s DNA double-helix model, or, more recently, Jennifer Doudna and Emmanuelle Charpentier’s CRISPR-Cas9 genome editing technique.

How did a team that just a few years ago was teaching an AI to master a 3,000-year-old game end up training one to answer a question plaguing biologists for five decades? That, says Briana Brownell, data scientist and founder of the AI company PureStrategy, is the beauty of artificial intelligence: The same kind of algorithm can be used for very different things.

“Whenever you have a problem that you want to solve with AI,” she says, “you need to figure out how to get the right data into the model—and then the right sort of output that you can translate back into the real world.”

DeepMind’s success, she says, wasn’t so much a function of picking the right neural nets but rather “how they set up the problem in a sophisticated enough way that the neural network-based modeling [could] actually answer the question.”

AlphaFold showed promise in 2018, when DeepMind introduced a previous iteration of their AI at CASP13, achieving the highest accuracy among all participants. The team had trained its to model target shapes from scratch, without using previously solved proteins as templates.

For 2020 they deployed new deep learning architectures into the AI, using an attention-based model that was trained end-to-end. Attention in a deep learning network refers to a component that manages and quantifies the interdependence between the input and output elements, as well as between the input elements themselves.

The system was trained on public datasets of the approximately 170,000 known experimental protein structures in addition to databases with protein sequences of unknown structures.

“If you look at the difference between their entry two years ago and this one, the structure of the AI system was different,” says Brownell. “This time, they’ve figured out how to translate the real world into data … [and] created an output that could be translated back into the real world.”

Like any AI system, AlphaFold may need to contend with biases in the training data. For instance, Brownell says, AlphaFold is using available information about protein structure that has been measured in other ways. However, there are also many proteins with as yet unknown 3D structures. Therefore, she says, a bias could conceivably creep in toward those kinds of proteins that we have more structural data for.

Thornton says it’s difficult to predict how long it will take for AlphaFold’s breakthrough to translate into real-world applications.

“We only have experimental structures for about 10 per cent of the 20,000 proteins [in] the human body,” she says. “A powerful AI model could unveil the structures of the other 90 per cent.”

Apart from increasing our understanding of human biology and health, she adds, “it is the first real step toward… building proteins that fulfill a specific function. From protein therapeutics to biofuels or enzymes that eat plastic, the possibilities are endless.” Continue reading

Posted in Human Robots