Tag Archives: Male

#435822 The Internet Is Coming to the Rest of ...

Posted on September 26, 2019 by Android

People surf it. Spiders crawl it. Gophers navigate it.

Now, a leading group of cognitive biologists and computer scientists want to make the tools of the Internet accessible to the rest of the animal kingdom.

Dubbed the Interspecies Internet, the project aims to provide intelligent animals such as elephants, dolphins, magpies, and great apes with a means to communicate among each other and with people online.

And through artificial intelligence, virtual reality, and other digital technologies, researchers hope to crack the code of all the chirps, yips, growls, and whistles that underpin animal communication.

Oh, and musician Peter Gabriel is involved.

“We can use data analysis and technology tools to give non-humans a lot more choice and control,” the former Genesis frontman, dressed in his signature Nehru-style collar shirt and loose, open waistcoat, told IEEE Spectrum at the inaugural Interspecies Internet Workshop, held Monday in Cambridge, Mass. “This will be integral to changing our relationship with the natural world.”

The workshop was a long time in the making.

Eighteen years ago, Gabriel visited a primate research center in Atlanta, Georgia, where he jammed with two bonobos, a male named Kanzi and his half-sister Panbanisha. It was the first time either bonobo had sat at a piano before, and both displayed an exquisite sense of musical timing and melody.

Gabriel seemed to be speaking to the great apes through his synthesizer. It was a shock to the man who once sang “Shock the Monkey.”

“It blew me away,” he says.

Add in the bonobos’ ability to communicate by pointing to abstract symbols, Gabriel notes, and “you’d have to be deaf, dumb, and very blind not to notice language being used.”

Gabriel eventually teamed up with Internet protocol co-inventor Vint Cerf, cognitive psychologist Diana Reiss, and IoT pioneer Neil Gershenfeld to propose building an Interspecies Internet. Presented in a 2013 TED Talk as an “idea in progress,” the concept proved to be ahead of the technology.

“It wasn’t ready,” says Gershenfeld, director of MIT’s Center for Bits and Atoms. “It needed to incubate.”

So, for the past six years, the architects of the Dolittlesque initiative embarked on two small pilot projects, one for dolphins and one for chimpanzees.

At her Hunter College lab in New York City, Reiss developed what she calls the D-Pad—a touchpad for dolphins.

Reiss had been trying for years to create an underwater touchscreen with which to probe the cognition and communication skills of bottlenose dolphins. But “it was a nightmare coming up with something that was dolphin-safe and would work,” she says.

Her first attempt emitted too much heat. A Wii-like system of gesture recognition proved too difficult to install in the dolphin tanks.

Eventually, she joined forces with Rockefeller University biophysicist Marcelo Magnasco and invented an optical detection system in which images and infrared sensors are projected through an underwater viewing window onto a glass panel, allowing the dolphins to play specially designed apps, including one dubbed Whack-a-Fish.

Meanwhile, in the United Kingdom, Gabriel worked with Alison Cronin, director of the ape rescue center Monkey World, to test the feasibility of using FaceTime with chimpanzees.

The chimps engaged with the technology, Cronin reported at this week’s workshop. However, our hominid cousins proved as adept at videotelephonic discourse as my three-year-old son is at video chatting with his grandparents—which is to say, there was a lot of pass-the-banana-through-the-screen and other silly games, and not much meaningful conversation.

“We can use data analysis and technology tools to give non-humans a lot more choice and control.”
—Peter Gabriel

The buggy, rudimentary attempt at interspecies online communication—what Cronin calls her “Max Headroom experiment”—shows that building the Interspecies Internet will not be as simple as giving out Skype-enabled tablets to smart animals.

“There are all sorts of problems with creating a human-centered experience for another animal,” says Gabriel Miller, director of research and development at the San Diego Zoo.

Miller has been working on animal-focused sensory tools such as an “Elephone” (for elephants) and a “Joybranch” (for birds), but it’s not easy to design efficient interactive systems for other creatures—and for the Interspecies Internet to be successful, Miller points out, “that will be super-foundational.”

Researchers are making progress on natural language processing of animal tongues. Through a non-profit organization called the Earth Species Project, former Firefox designer Aza Raskin and early Twitter engineer Britt Selvitelle are applying deep learning algorithms developed for unsupervised machine translation of human languages to fashion a Rosetta Stone–like tool capable of interpreting the vocalizations of whales, primates, and other animals.

Inspired by the scientists who first documented the complex sonic arrangements of humpback whales in the 1960s—a discovery that ushered in the modern marine conservation movement—Selvitelle hopes that an AI-powered animal translator can have a similar effect on environmentalism today.

“A lot of shifts happen when someone who doesn’t have a voice gains a voice,” he says.

A challenge with this sort of AI software remains verification and validation. Normally, machine-learning algorithms are benchmarked against a human expert, but who is to say if a cybernetic translation of a sperm whale’s clicks is accurate or not?

One could back-translate an English expression into sperm whale-ese and then into English again. But with the great apes, there might be a better option.

According to primatologist Sue Savage-Rumbaugh, expertly trained bonobos could serve as bilingual interpreters, translating the argot of apes into the parlance of people, and vice versa.

Not just any trained ape will do, though. They have to grow up in a mixed Pan/Homo environment, as Kanzi and Panbanisha were.

“If I can have a chat with a cow, maybe I can have more compassion for it.”
—Jeremy Coller

Those bonobos were raised effectively from birth both by Savage-Rumbaugh, who taught the animals to understand spoken English and to communicate via hundreds of different pictographic “lexigrams,” and a bonobo mother named Matata that had lived for six years in the Congolese rainforests before her capture.

Unlike all other research primates—which are brought into captivity as infants, reared by human caretakers, and have limited exposure to their natural cultures or languages—those apes thus grew up fluent in both bonobo and human.

Panbanisha died in 2012, but Kanzi, aged 38, is still going strong, living at an ape sanctuary in Des Moines, Iowa. Researchers continue to study his cognitive abilities—Francine Dolins, a primatologist at the University of Michigan-Dearborn, is running one study in which Kanzi and other apes hunt rabbits and forage for fruit through avatars on a touchscreen. Kanzi could, in theory, be recruited to check the accuracy of any Google Translate–like app for bonobo hoots, barks, grunts, and cries.

Alternatively, Kanzi could simply provide Internet-based interpreting services for our two species. He’s already proficient at video chatting with humans, notes Emily Walco, a PhD student at Harvard University who has personally Skyped with Kanzi. “He was super into it,” Walco says.

And if wild bonobos in Central Africa can be coaxed to gather around a computer screen, Savage-Rumbaugh is confident Kanzi could communicate with them that way. “It can all be put together,” she says. “We can have an Interspecies Internet.”

“Both the technology and the knowledge had to advance,” Savage-Rumbaugh notes. However, now, “the techniques that we learned could really be extended to a cow or a pig.”

That’s music to the ears of Jeremy Coller, a private equity specialist whose foundation partially funded the Interspecies Internet Workshop. Coller is passionate about animal welfare and has devoted much of his philanthropic efforts toward the goal of ending factory farming.

At the workshop, his foundation announced the creation of the Coller Doolittle Prize, a US $100,000 award to help fund further research related to the Interspecies Internet. (A working group also formed to synthesize plans for the emerging field, to facilitate future event planning, and to guide testing of shared technology platforms.)

Why would a multi-millionaire with no background in digital communication systems or cognitive psychology research want to back the initiative? For Coller, the motivation boils to interspecies empathy.

“If I can have a chat with a cow,” he says, “maybe I can have more compassion for it.”

An abridged version of this post appears in the September 2019 print issue as “Elephants, Dolphins, and Chimps Need the Internet, Too.” Continue reading →

Posted in Human Robots

#435522 Harvard’s Smart Exo-Shorts Talk to the ...

Posted on August 20, 2019 by Android

Exosuits don’t generally scream “fashionable” or “svelte.” Take the mind-controlled robotic exoskeleton that allowed a paraplegic man to kick off the World Cup back in 2014. Is it cool? Hell yeah. Is it practical? Not so much.

Yapping about wearability might seem childish when the technology already helps people with impaired mobility move around dexterously. But the lesson of the ill-fated Google Glassholes, which includes an awkward dorky head tilt and an assuming voice command, clearly shows that wearable computer assistants can’t just work technologically—they have to look natural and allow the user to behave like as usual. They have to, in a sense, disappear.

To Dr. Jose Pons at the Legs + Walking Ability Lab in Chicago, exosuits need three main selling points to make it in the real world. One, they have to physically interact with their wearer and seamlessly deliver assistance when needed. Two, they should cognitively interact with the host to guide and control the robot at all times. Finally, they need to feel like a second skin—move with the user without adding too much extra mass or reducing mobility.

This week, a US-Korean collaboration delivered the whole shebang in a Lululemon-style skin-hugging package combined with a retro waist pack. The portable exosuit, weighing only 11 pounds, looks like a pair of spandex shorts but can support the wearer’s hip movement when needed. Unlike their predecessors, the shorts are embedded with sensors that let them know when the wearer is walking versus running by analyzing gait.

Switching between the two movement modes may not seem like much, but what naturally comes to our brains doesn’t translate directly to smart exosuits. “Walking and running have fundamentally different biomechanics, which makes developing devices that assist both gaits challenging,” the team said. Their algorithm, computed in the cloud, allows the wearer to easily switch between both, with the shorts providing appropriate hip support that makes the movement experience seamless.

To Pons, who was not involved in the research but wrote a perspective piece, the study is an exciting step towards future exosuits that will eventually disappear under the skin—that is, implanted neural interfaces to control robotic assistance or activate the user’s own muscles.

“It is realistic to think that we will witness, in the next several years…robust human-robot interfaces to command wearable robotics based on…the neural code of movement in humans,” he said.

A “Smart” Exosuit Hack
There are a few ways you can hack a human body to move with an exosuit. One is using implanted electrodes inside the brain or muscles to decipher movement intent. With heavy practice, a neural implant can help paralyzed people walk again or dexterously move external robotic arms. But because the technique requires surgery, it’s not an immediate sell for people who experience low mobility because of aging or low muscle tone.

The other approach is to look to biophysics. Rather than decoding neural signals that control movement, here the idea is to measure gait and other physical positions in space to decipher intent. As you can probably guess, accurately deciphering user intent isn’t easy, especially when the wearable tries to accommodate multiple gaits. But the gains are many: there’s no surgery involved, and the wearable is low in energy consumption.

Double Trouble
The authors decided to tackle an everyday situation. You’re walking to catch the train to work, realize you’re late, and immediately start sprinting.

That seemingly easy conversion hides a complex switch in biomechanics. When you walk, your legs act like an inverted pendulum that swing towards a dedicated center in a predictable way. When you run, however, the legs move more like a spring-loaded system, and the joints involved in the motion differ from a casual stroll. Engineering an assistive wearable for each is relatively simple; making one for both is exceedingly hard.

Led by Dr. Conor Walsh at Harvard University, the team started with an intuitive idea: assisted walking and running requires specialized “actuation” profiles tailored to both. When the user is moving in a way that doesn’t require assistance, the wearable needs to be out of the way so that it doesn’t restrict mobility. A quick analysis found that assisting hip extension has the largest impact, because it’s important to both gaits and doesn’t add mass to the lower legs.

Building on that insight, the team made a waist belt connected to two thigh wraps, similar to a climbing harness. Two electrical motors embedded inside the device connect the waist belt to other components through a pulley system to help the hip joints move. The whole contraption weighed about 11 lbs and didn’t obstruct natural movement.

Next, the team programmed two separate supporting profiles for walking and running. The goal was to reduce the “metabolic cost” for both movements, so that the wearer expends as little energy as needed. To switch between the two programs, they used a cloud-based classification algorithm to measure changes in energy fluctuation to figure out what mode—running or walking—the user is in.

Smart Booster
Initial trials on treadmills were highly positive. Six male volunteers with similar age and build donned the exosuit and either ran or walked on the treadmill at varying inclines. The algorithm performed perfectly at distinguishing between the two gaits in all conditions, even at steep angles.

An outdoor test with eight volunteers also proved the algorithm nearly perfect. Even on uneven terrain, only two steps out of all test trials were misclassified. In an additional trial on mud or snow, the algorithm performed just as well.

“The system allows the wearer to use their preferred gait for each speed,” the team said.

Software excellence translated to performance. A test found that the exosuit reduced the energy for walking by over nine percent and running by four percent. It may not sound like much, but the range of improvement is meaningful in athletic performance. Putting things into perspective, the team said, the metabolic rate reduction during walking is similar to taking 16 pounds off at the waist.

The Wearable Exosuit Revolution
The study’s lightweight exoshorts are hardly the only players in town. Back in 2017, SRI International’s spin-off, Superflex, engineered an Aura suit to support mobility in the elderly. The Aura used a different mechanism: rather than a pulley system, it incorporated a type of smart material that contracts in a manner similar to human muscles when zapped with electricity.

Embedded with a myriad of sensors for motion, accelerometers and gyroscopes, Aura’s smartness came from mini-computers that measure how fast the wearer is moving and track the user’s posture. The data were integrated and processed locally inside hexagon-shaped computing pods near the thighs and upper back. The pods also acted as the control center for sending electrical zaps to give the wearer a boost when needed.

Around the same time, a collaboration between Harvard’s Wyss Institute and ReWalk Robotics introduced a fabric-based wearable robot to assist a wearer’s legs for balance and movement. Meanwhile, a Swiss team coated normal fabric with electroactive material to weave soft, pliable artificial “muscles” that move with the skin.

Although health support is the current goal, the military is obviously interested in similar technologies to enhance soldiers’ physicality. Superflex’s Aura, for example, was originally inspired by technology born from DARPA’s Warrior Web Program, which aimed to reduce a soldier’s mechanical load.

That said, military gear has had a long history of trickling down to consumer use. Similar to the way camouflage, cargo pants, and GORE-TEX trickled down into the consumer ecosphere, it’s not hard to imagine your local Target eventually stocking intelligent exowear.

Image and Video Credit: Wyss Institute at Harvard University. Continue reading →

Posted in Human Robots

#435196 Avatar Love? New ‘Black Mirror’ ...

Posted on June 17, 2019 by Android

This week, the widely-anticipated fifth season of the dystopian series Black Mirror was released on Netflix. The storylines this season are less focused on far-out scenarios and increasingly aligned with current issues. With only three episodes, this season raises more questions than it answers, often leaving audiences bewildered.

The episode Smithereens explores our society’s crippling addiction to social media platforms and the monopoly they hold over our data. In Rachel, Jack and Ashley Too, we see the disruptive impact of technologies on the music and entertainment industry, and the price of fame for artists in the digital world. Like most Black Mirror episodes, these explore the sometimes disturbing implications of tech advancements on humanity.

But once again, in the midst of all the doom and gloom, the creators of the series leave us with a glimmer of hope. Aligned with Pride month, the episode Striking Vipers explores the impact of virtual reality on love, relationships, and sexual fluidity.

*The review contains a few spoilers.*

Striking Vipers
The first episode of the season, Striking Vipers may be one of the most thought-provoking episodes in Black Mirror history. Reminiscent of previous episodes San Junipero and Hang the DJ, the writers explore the potential for technology to transform human intimacy.

The episode tells the story of two old friends, Danny and Karl, whose friendship is reignited in an unconventional way. Karl unexpectedly appears at Danny’s 38th birthday and reintroduces him to the VR version of a game they used to play years before. In the game Striking Vipers X, each of the players is represented by an avatar of their choice in an uncanny digital reality. Following old tradition, Karl chooses to become the female fighter, Roxanne, and Danny takes on the role of the male fighter, Lance. The state-of-the-art VR headsets appear to use an advanced form of brain-machine interface to allow each player to be fully immersed in the virtual world, emulating all physical sensations.

To their surprise (and confusion), Danny and Karl find themselves transitioning from fist-fighting to kissing. Over the course of many games, they continue to explore a sexual and romantic relationship in the virtual world, leaving them confused and distant in the real world. The virtual and physical realities begin to blur, and so do the identities of the players with their avatars. Danny, who is married (in a heterosexual relationship) and is a father, begins to carry guilt and confusion in the real world. They both wonder if there would be any spark between them in real life.

The brain-machine interface (BMI) depicted in the episode is still science fiction, but that hasn’t stopped innovators from pushing the technology forward. Experts today are designing more intricate BMI systems while programming better algorithms to interpret the neural signals they capture. Scientists have already succeeded in enabling paralyzed patients to type with their minds, and are even allowing people to communicate with one another purely through brainwaves.

The convergence of BMIs with virtual reality and artificial intelligence could make the experience of such immersive digital realities possible. Virtual reality, too, is decreasing exponentially in cost and increasing in quality.

The narrative provides meaningful commentary on another tech area—gaming. It highlights video games not necessarily as addictive distractions, but rather as a platform for connecting with others in a deeper way. This is already very relevant. Video games like Final Fantasy are often a tool for meaningful digital connections for their players.

The Implications of Virtual Reality on Love and Relationships
The narrative of Striking Vipers raises many novel questions about the implications of immersive technologies on relationships: could the virtual world allow us a safe space to explore suppressed desires? Can virtual avatars make it easier for us to show affection to those we care about? Can a sexual or romantic encounter in the digital world be considered infidelity?

Above all, the episode explores the therapeutic possibilities of such technologies. While many fears about virtual reality had been raised in previous seasons of Black Mirror, this episode was focused on its potential. This includes the potential of immersive technology to be a source of liberation, meaningful connections, and self-exploration, as well as a tool for realizing our true identities and desires.

Once again, this is aligned with emerging trends in VR. We are seeing the rise of social VR applications and platforms that allow you to hang out with your friends and family as avatars in the virtual space. The technology is allowing for animation movies, such as Coco VR, to become an increasingly social and interactive experience. Considering that meaningful social interaction can alleviate depression and anxiety, such applications could contribute to well-being.

Techno-philosopher and National Geographic host Jason Silva points out that immersive media technologies can be “engines of empathy.” VR allows us to enter virtual spaces that mimic someone else’s state of mind, allowing us to empathize with the way they view the world. Silva said, “Imagine the intimacy that becomes possible when people meet and they say, ‘Hey, do you want to come visit my world? Do you want to see what it’s like to be inside my head?’”

What is most fascinating about Striking Vipers is that it explores how we may redefine love with virtual reality; we are introduced to love between virtual avatars. While this kind of love may seem confusing to audiences, it may be one of the complex implications of virtual reality on human relationships.

In many ways, the title Black Mirror couldn’t be more appropriate, as each episode serves as a mirror to the most disturbing aspects of our psyches as they get amplified through technology. However, what we see in uplifting and thought-provoking plots like Striking Vipers, San Junipero, and Hang The DJ is that technology could also amplify the most positive aspects of our humanity. This includes our powerful capacity to love.

Image Credit: Arsgera / Shutterstock.com Continue reading →

Posted in Human Robots

#434753 Top Takeaways From The Economist ...

Posted on March 14, 2019 by Android

Over the past few years, the word ‘innovation’ has degenerated into something of a buzzword. In fact, according to Vijay Vaitheeswaran, US business editor at The Economist, it’s one of the most abused words in the English language.

The word is over-used precisely because we’re living in a great age of invention. But the pace at which those inventions are changing our lives is fast, new, and scary.

So what strategies do companies need to adopt to make sure technology leads to growth that’s not only profitable, but positive? How can business and government best collaborate? Can policymakers regulate the market without suppressing innovation? Which technologies will impact us most, and how soon?

At The Economist Innovation Summit in Chicago last week, entrepreneurs, thought leaders, policymakers, and academics shared their insights on the current state of exponential technologies, and the steps companies and individuals should be taking to ensure a tech-positive future. Here’s their expert take on the tech and trends shaping the future.

Blockchain
There’s been a lot of hype around blockchain; apparently it can be used for everything from distributing aid to refugees to voting. However, it’s too often conflated with cryptocurrencies like Bitcoin, and we haven’t heard of many use cases. Where does the technology currently stand?

Julie Sweet, chief executive of Accenture North America, emphasized that the technology is still in its infancy. “Everything we see today are pilots,” she said. The most promising of these pilots are taking place across three different areas: supply chain, identity, and financial services.

When you buy something from outside the US, Sweet explained, it goes through about 80 different parties. 70 percent of the relevant data is replicated and is prone to error, with paper-based documents often to blame. Blockchain is providing a secure way to eliminate paper in supply chains, upping accuracy and cutting costs in the process.

One of the most prominent use cases in the US is Walmart—the company has mandated that all suppliers in its leafy greens segment be on a blockchain, and its food safety has improved as a result.

Beth Devin, head of Citi Ventures’ innovation network, added “Blockchain is an infrastructure technology. It can be leveraged in a lot of ways. There’s so much opportunity to create new types of assets and securities that aren’t accessible to people today. But there’s a lot to figure out around governance.”

Open Source Technology
Are the days of proprietary technology numbered? More and more companies and individuals are making their source code publicly available, and its benefits are thus more widespread than ever before. But what are the limitations and challenges of open source tech, and where might it go in the near future?

Bob Lord, senior VP of cognitive applications at IBM, is a believer. “Open-sourcing technology helps innovation occur, and it’s a fundamental basis for creating great technology solutions for the world,” he said. However, the biggest challenge for open source right now is that companies are taking out more than they’re contributing back to the open-source world. Lord pointed out that IBM has a rule about how many lines of code employees take out relative to how many lines they put in.

Another challenge area is open governance; blockchain by its very nature should be transparent and decentralized, with multiple parties making decisions and being held accountable. “We have to embrace open governance at the same time that we’re contributing,” Lord said. He advocated for a hybrid-cloud environment where people can access public and private data and bring it together.

Augmented and Virtual Reality
Augmented and virtual reality aren’t just for fun and games anymore, and they’ll be even less so in the near future. According to Pearly Chen, vice president at HTC, they’ll also go from being two different things to being one and the same. “AR overlays digital information on top of the real world, and VR transports you to a different world,” she said. “In the near future we will not need to delineate between these two activities; AR and VR will come together naturally, and will change everything we do as we know it today.”

For that to happen, we’ll need a more ergonomically friendly device than we have today for interacting with this technology. “Whenever we use tech today, we’re multitasking,” said product designer and futurist Jody Medich. “When you’re using GPS, you’re trying to navigate in the real world and also manage this screen. Constant task-switching is killing our brain’s ability to think.” Augmented and virtual reality, she believes, will allow us to adapt technology to match our brain’s functionality.

This all sounds like a lot of fun for uses like gaming and entertainment, but what about practical applications? “Ultimately what we care about is how this technology will improve lives,” Chen said.

A few ways that could happen? Extended reality will be used to simulate hazardous real-life scenarios, reduce the time and resources needed to bring a product to market, train healthcare professionals (such as surgeons), or provide therapies for patients—not to mention education. “Think about the possibilities for children to learn about history, science, or math in ways they can’t today,” Chen said.

Quantum Computing
If there’s one technology that’s truly baffling, it’s quantum computing. Qubits, entanglement, quantum states—it’s hard to wrap our heads around these concepts, but they hold great promise. Where is the tech right now?

Mandy Birch, head of engineering strategy at Rigetti Computing, thinks quantum development is starting slowly but will accelerate quickly. “We’re at the innovation stage right now, trying to match this capability to useful applications,” she said. “Can we solve problems cheaper, better, and faster than classical computers can do?” She believes quantum’s first breakthrough will happen in two to five years, and that is highest potential is in applications like routing, supply chain, and risk optimization, followed by quantum chemistry (for materials science and medicine) and machine learning.

David Awschalom, director of the Chicago Quantum Exchange and senior scientist at Argonne National Laboratory, believes quantum communication and quantum sensing will become a reality in three to seven years. “We’ll use states of matter to encrypt information in ways that are completely secure,” he said. A quantum voting system, currently being prototyped, is one application.

Who should be driving quantum tech development? The panelists emphasized that no one entity will get very far alone. “Advancing quantum tech will require collaboration not only between business, academia, and government, but between nations,” said Linda Sapochak, division director of materials research at the National Science Foundation. She added that this doesn’t just go for the technology itself—setting up the infrastructure for quantum will be a big challenge as well.

Space
Space has always been the final frontier, and it still is—but it’s not quite as far-removed from our daily lives now as it was when Neil Armstrong walked on the moon in 1969.

The space industry has always been funded by governments and private defense contractors. But in 2009, SpaceX launched its first commercial satellite, and in subsequent years have drastically cut the cost of spaceflight. More importantly, they published their pricing, which brought transparency to a market that hadn’t seen it before.

Entrepreneurs around the world started putting together business plans, and there are now over 400 privately-funded space companies, many with consumer applications.

Chad Anderson, CEO of Space Angels and managing partner of Space Capital, pointed out that the technology floating around in space was, until recently, archaic. “A few NASA engineers saw they had more computing power in their phone than there was in satellites,” he said. “So they thought, ‘why don’t we just fly an iPhone?’” They did—and it worked.

Now companies have networks of satellites monitoring the whole planet, producing a huge amount of data that’s valuable for countless applications like agriculture, shipping, and observation. “A lot of people underestimate space,” Anderson said. “It’s already enabling our modern global marketplace.”

Next up in the space realm, he predicts, are mining and tourism.

Artificial Intelligence and the Future of Work
From the US to Europe to Asia, alarms are sounding about AI taking our jobs. What will be left for humans to do once machines can do everything—and do it better?

These fears may be unfounded, though, and are certainly exaggerated. It’s undeniable that AI and automation are changing the employment landscape (not to mention the way companies do business and the way we live our lives), but if we build these tools the right way, they’ll bring more good than harm, and more productivity than obsolescence.

Accenture’s Julie Sweet emphasized that AI alone is not what’s disrupting business and employment. Rather, it’s what she called the “triple A”: automation, analytics, and artificial intelligence. But even this fear-inducing trifecta of terms doesn’t spell doom, for workers or for companies. Accenture has automated 40,000 jobs—and hasn’t fired anyone in the process. Instead, they’ve trained and up-skilled people. The most important drivers to scale this, Sweet said, are a commitment by companies and government support (such as tax credits).

Imbuing AI with the best of human values will also be critical to its impact on our future. Tracy Frey, Google Cloud AI’s director of strategy, cited the company’s set of seven AI principles. “What’s important is the governance process that’s put in place to support those principles,” she said. “You can’t make macro decisions when you have technology that can be applied in many different ways.”

High Risks, High Stakes
This year, Vaitheeswaran said, 50 percent of the world’s population will have internet access (he added that he’s disappointed that percentage isn’t higher given the proliferation of smartphones). As technology becomes more widely available to people around the world and its influence grows even more, what are the biggest risks we should be monitoring and controlling?

Information integrity—being able to tell what’s real from what’s fake—is a crucial one. “We’re increasingly operating in siloed realities,” said Renee DiResta, director of research at New Knowledge and head of policy at Data for Democracy. “Inadvertent algorithmic amplification on social media elevates certain perspectives—what does that do to us as a society?”

Algorithms have also already been proven to perpetuate the bias of the people who create it—and those people are often wealthy, white, and male. Ensuring that technology doesn’t propagate unfair bias will be crucial to its ability to serve a diverse population, and to keep societies from becoming further polarized and inequitable. The polarization of experience that results from pronounced inequalities within countries, Vaitheeswaran pointed out, can end up undermining democracy.

We’ll also need to walk the line between privacy and utility very carefully. As Dan Wagner, founder of Civis Analytics put it, “We want to ensure privacy as much as possible, but open access to information helps us achieve important social good.” Medicine in the US has been hampered by privacy laws; if, for example, we had more data about biomarkers around cancer, we could provide more accurate predictions and ultimately better healthcare.

But going the Chinese way—a total lack of privacy—is likely not the answer, either. “We have to be very careful about the way we bake rights and freedom into our technology,” said Alex Gladstein, chief strategy officer at Human Rights Foundation.

Technology’s risks are clearly as fraught as its potential is promising. As Gary Shapiro, chief executive of the Consumer Technology Association, put it, “Everything we’ve talked about today is simply a tool, and can be used for good or bad.”

The decisions we’re making now, at every level—from the engineers writing algorithms, to the legislators writing laws, to the teenagers writing clever Instagram captions—will determine where on the spectrum we end up.

Image Credit: Rudy Balasko / Shutterstock.com Continue reading →

Posted in Human Robots

#434508 The Top Biotech and Medicine Advances to ...

Posted on January 22, 2019 by Android

2018 was bonkers for science.

From a woman who gave birth using a transplanted uterus, to the infamous CRISPR baby scandal, to forensics adopting consumer-based genealogy test kits to track down criminals, last year was a factory churning out scientific “whoa” stories with consequences for years to come.

With CRISPR still in the headlines, Britain ready to bid Europe au revoir, and multiple scientific endeavors taking off, 2019 is shaping up to be just as tumultuous.

Here are the science and health stories that may blow up in the new year. But first, a note of caveat: predicting the future is tough. Forecasting is the lovechild between statistics and (a good deal of) intuition, and entire disciplines have been dedicated to the endeavor. But January is the perfect time to gaze into the crystal ball for wisps of insight into the year to come. Last year we predicted the widespread approval of gene therapy products—on the most part, we nailed it. This year we’re hedging our bets with multiple predictions.

Gene Drives Used in the Wild
The concept of gene drives scares many, for good reason. Gene drives are a step up in severity (and consequences) from CRISPR and other gene-editing tools. Even with germline editing, in which the sperm, egg, or embryos are altered, gene editing affects just one genetic line—one family—at least at the beginning, before they reproduce with the general population.

Gene drives, on the other hand, have the power to wipe out entire species.

In a nutshell, they’re little bits of DNA code that help a gene transfer from parent to child with almost 100 percent perfect probability. The “half of your DNA comes from dad, the other comes from mom” dogma? Gene drives smash that to bits.

In other words, the only time one would consider using a gene drive is to change the genetic makeup of an entire population. It sounds like the plot of a supervillain movie, but scientists have been toying around with the idea of deploying the technology—first in mosquitoes, then (potentially) in rodents.

By releasing just a handful of mutant mosquitoes that carry gene drives for infertility, for example, scientists could potentially wipe out entire populations that carry infectious scourges like malaria, dengue, or Zika. The technology is so potent—and dangerous—the US Defense Advances Research Projects Agency is shelling out $65 million to suss out how to deploy, control, counter, or even reverse the effects of tampering with ecology.

Last year, the U.N. gave a cautious go-ahead for the technology to be deployed in the wild in limited terms. Now, the first release of a genetically modified mosquito is set for testing in Burkina Faso in Africa—the first-ever field experiment involving gene drives.

The experiment will only release mosquitoes in the Anopheles genus, which are the main culprits transferring disease. As a first step, over 10,000 male mosquitoes are set for release into the wild. These dudes are genetically sterile but do not cause infertility, and will help scientists examine how they survive and disperse as a preparation for deploying gene-drive-carrying mosquitoes.

Hot on the project’s heels, the nonprofit consortium Target Malaria, backed by the Bill and Melinda Gates foundation, is engineering a gene drive called Mosq that will spread infertility across the population or kill out all female insects. Their attempt to hack the rules of inheritance—and save millions in the process—is slated for 2024.

A Universal Flu Vaccine
People often brush off flu as a mere annoyance, but the infection kills hundreds of thousands each year based on the CDC’s statistical estimates.

The flu virus is actually as difficult of a nemesis as HIV—it mutates at an extremely rapid rate, making effective vaccines almost impossible to engineer on time. Scientists currently use data to forecast the strains that will likely explode into an epidemic and urge the public to vaccinate against those predictions. That’s partly why, on average, flu vaccines only have a success rate of roughly 50 percent—not much better than a coin toss.

Tired of relying on educated guesses, scientists have been chipping away at a universal flu vaccine that targets all strains—perhaps even those we haven’t yet identified. Often referred to as the “holy grail” in epidemiology, these vaccines try to alert our immune systems to parts of a flu virus that are least variable from strain to strain.

Last November, a first universal flu vaccine developed by BiondVax entered Phase 3 clinical trials, which means it’s already been proven safe and effective in a small numbers and is now being tested in a broader population. The vaccine doesn’t rely on dead viruses, which is a common technique. Rather, it uses a small chain of amino acids—the chemical components that make up proteins—to stimulate the immune system into high alert.

With the government pouring $160 million into the research and several other universal candidates entering clinical trials, universal flu vaccines may finally experience a breakthrough this year.

In-Body Gene Editing Shows Further Promise
CRISPR and other gene editing tools headed the news last year, including both downers suggesting we already have immunity to the technology and hopeful news of it getting ready for treating inherited muscle-wasting diseases.

But what wasn’t widely broadcasted was the in-body gene editing experiments that have been rolling out with gusto. Last September, Sangamo Therapeutics in Richmond, California revealed that they had injected gene-editing enzymes into a patient in an effort to correct a genetic deficit that prevents him from breaking down complex sugars.

The effort is markedly different than the better-known CAR-T therapy, which extracts cells from the body for genetic engineering before returning them to the hosts. Rather, Sangamo’s treatment directly injects viruses carrying the edited genes into the body. So far, the procedure looks to be safe, though at the time of reporting it was too early to determine effectiveness.

This year the company hopes to finally answer whether it really worked.

If successful, it means that devastating genetic disorders could potentially be treated with just a few injections. With a gamut of new and more precise CRISPR and other gene-editing tools in the works, the list of treatable inherited diseases is likely to grow. And with the CRISPR baby scandal potentially dampening efforts at germline editing via regulations, in-body gene editing will likely receive more attention if Sangamo’s results return positive.

Neuralink and Other Brain-Machine Interfaces
Neuralink is the stuff of sci fi: tiny implanted particles into the brain could link up your biological wetware with silicon hardware and the internet.

But that’s exactly what Elon Musk’s company, founded in 2016, seeks to develop: brain-machine interfaces that could tinker with your neural circuits in an effort to treat diseases or even enhance your abilities.

Last November, Musk broke his silence on the secretive company, suggesting that he may announce something “interesting” in a few months, that’s “better than anyone thinks is possible.”

Musk’s aspiration for achieving symbiosis with artificial intelligence isn’t the driving force for all brain-machine interfaces (BMIs). In the clinics, the main push is to rehabilitate patients—those who suffer from paralysis, memory loss, or other nerve damage.

2019 may be the year that BMIs and neuromodulators cut the cord in the clinics. These devices may finally work autonomously within a malfunctioning brain, applying electrical stimulation only when necessary to reduce side effects without requiring external monitoring. Or they could allow scientists to control brains with light without needing bulky optical fibers.

Cutting the cord is just the first step to fine-tuning neurological treatments—or enhancements—to the tune of your own brain, and 2019 will keep on bringing the music.

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