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#436123 A Path Towards Reasonable Autonomous ...
Editor’s Note: The debate on autonomous weapons systems has been escalating over the past several years as the underlying technologies evolve to the point where their deployment in a military context seems inevitable. IEEE Spectrum has published a variety of perspectives on this issue. In summary, while there is a compelling argument to be made that autonomous weapons are inherently unethical and should be banned, there is also a compelling argument to be made that autonomous weapons could potentially make conflicts less harmful, especially to non-combatants. Despite an increasing amount of international attention (including from the United Nations), progress towards consensus, much less regulatory action, has been slow. The following workshop paper on autonomous weapons systems policy is remarkable because it was authored by a group of experts with very different (and in some cases divergent) views on the issue. Even so, they were able to reach consensus on a roadmap that all agreed was worth considering. It’s collaborations like this that could be the best way to establish a reasonable path forward on such a contentious issue, and with the permission of the authors, we’re excited to be able to share this paper (originally posted on Georgia Tech’s Mobile Robot Lab website) with you in its entirety.
Autonomous Weapon Systems: A Roadmapping Exercise
Over the past several years, there has been growing awareness and discussion surrounding the possibility of future lethal autonomous weapon systems that could fundamentally alter humanity’s relationship with violence in war. Lethal autonomous weapons present a host of legal, ethical, moral, and strategic challenges. At the same time, artificial intelligence (AI) technology could be used in ways that improve compliance with the laws of war and reduce non-combatant harm. Since 2014, states have come together annually at the United Nations to discuss lethal autonomous weapons systems1. Additionally, a growing number of individuals and non-governmental organizations have become active in discussions surrounding autonomous weapons, contributing to a rapidly expanding intellectual field working to better understand these issues. While a wide range of regulatory options have been proposed for dealing with the challenge of lethal autonomous weapons, ranging from a preemptive, legally binding international treaty to reinforcing compliance with existing laws of war, there is as yet no international consensus on a way forward.
The lack of an international policy consensus, whether codified in a formal document or otherwise, poses real risks. States could fall victim to a security dilemma in which they deploy untested or unsafe weapons that pose risks to civilians or international stability. Widespread proliferation could enable illicit uses by terrorists, criminals, or rogue states. Alternatively, a lack of guidance on which uses of autonomy are acceptable could stifle valuable research that could reduce the risk of non-combatant harm.
International debate thus far has predominantly centered around whether or not states should adopt a preemptive, legally-binding treaty that would ban lethal autonomous weapons before they can be built. Some of the authors of this document have called for such a treaty and would heartily support it, if states were to adopt it. Other authors of this document have argued an overly expansive treaty would foreclose the possibility of using AI to mitigate civilian harm. Options for international action are not binary, however, and there are a range of policy options that states should consider between adopting a comprehensive treaty or doing nothing.
The purpose of this paper is to explore the possibility of a middle road. If a roadmap could garner sufficient stakeholder support to have significant beneficial impact, then what elements could it contain? The exercise whose results are presented below was not to identify recommendations that the authors each prefer individually (the authors hold a broad spectrum of views), but instead to identify those components of a roadmap that the authors are all willing to entertain2. We, the authors, invite policymakers to consider these components as they weigh possible actions to address concerns surrounding autonomous weapons3.
Summary of Issues Surrounding Autonomous Weapons
There are a variety of issues that autonomous weapons raise, which might lend themselves to different approaches. A non-exhaustive list of issues includes:
The potential for beneficial uses of AI and autonomy that could improve precision and reliability in the use of force and reduce non-combatant harm.
Uncertainty about the path of future technology and the likelihood of autonomous weapons being used in compliance with the laws of war, or international humanitarian law (IHL), in different settings and on various timelines.
A desire for some degree of human involvement in the use of force. This has been expressed repeatedly in UN discussions on lethal autonomous weapon systems in different ways.
Particular risks surrounding lethal autonomous weapons specifically targeting personnel as opposed to vehicles or materiel.
Risks regarding international stability.
Risk of proliferation to terrorists, criminals, or rogue states.
Risk that autonomous systems that have been verified to be acceptable can be made unacceptable through software changes.
The potential for autonomous weapons to be used as scalable weapons enabling a small number of individuals to inflict very large-scale casualties at low cost, either intentionally or accidentally.
Summary of Components
A time-limited moratorium on the development, deployment, transfer, and use of anti-personnel lethal autonomous weapon systems4. Such a moratorium could include exceptions for certain classes of weapons.
Define guiding principles for human involvement in the use of force.
Develop protocols and/or technological means to mitigate the risk of unintentional escalation due to autonomous systems.
Develop strategies for preventing proliferation to illicit uses, such as by criminals, terrorists, or rogue states.
Conduct research to improve technologies and human-machine systems to reduce non-combatant harm and ensure IHL compliance in the use of future weapons.
Component 1:
States should consider adopting a five-year, renewable moratorium on the development, deployment, transfer, and use of anti-personnel lethal autonomous weapon systems. Anti-personnel lethal autonomous weapon systems are defined as weapons systems that, once activated, can select and engage dismounted human targets without further intervention by a human operator, possibly excluding systems such as:
Fixed-point defensive systems with human supervisory control to defend human-occupied bases or installations
Limited, proportional, automated counter-fire systems that return fire in order to provide immediate, local defense of humans
Time-limited pursuit deterrent munitions or systems
Autonomous weapon systems with size above a specified explosive weight limit that select as targets hand-held weapons, such as rifles, machine guns, anti-tank weapons, or man-portable air defense systems, provided there is adequate protection for non-combatants and ensuring IHL compliance5
The moratorium would not apply to:
Anti-vehicle or anti-materiel weapons
Non-lethal anti-personnel weapons
Research on ways of improving autonomous weapon technology to reduce non-combatant harm in future anti-personnel lethal autonomous weapon systems
Weapons that find, track, and engage specific individuals whom a human has decided should be engaged within a limited predetermined period of time and geographic region
Motivation:
This moratorium would pause development and deployment of anti-personnel lethal autonomous weapons systems to allow states to better understand the systemic risks of their use and to perform research that improves their safety, understandability, and effectiveness. Particular objectives could be to:
ensure that, prior to deployment, anti-personnel lethal autonomous weapons can be used in ways that are equal to or outperform humans in their compliance with IHL (other conditions may also apply prior to deployment being acceptable);
lay the groundwork for a potentially legally binding diplomatic instrument; and
decrease the geopolitical pressure on countries to deploy anti-personnel lethal autonomous weapons before they are reliable and well-understood.
Compliance Verification:
As part of a moratorium, states could consider various approaches to compliance verification. Potential approaches include:
Developing an industry cooperation regime analogous to that mandated under the Chemical Weapons Convention, whereby manufacturers must know their customers and report suspicious purchases of significant quantities of items such as fixed-wing drones, quadcopters, and other weaponizable robots.
Encouraging states to declare inventories of autonomous weapons for the purposes of transparency and confidence-building.
Facilitating scientific exchanges and military-to-military contacts to increase trust, transparency, and mutual understanding on topics such as compliance verification and safe operation of autonomous systems.
Designing control systems to require operator identity authentication and unalterable records of operation; enabling post-hoc compliance checks in case of plausible evidence of non-compliant autonomous weapon attacks.
Relating the quantity of weapons to corresponding capacities for human-in-the-loop operation of those weapons.
Designing weapons with air-gapped firing authorization circuits that are connected to the remote human operator but not to the on-board automated control system.
More generally, avoiding weapon designs that enable conversion from compliant to non-compliant categories or missions solely by software updates.
Designing weapons with formal proofs of relevant properties—e.g., the property that the weapon is unable to initiate an attack without human authorization. Proofs can, in principle, be provided using cryptographic techniques that allow the proofs to be checked by a third party without revealing any details of the underlying software.
Facilitate access to (non-classified) AI resources (software, data, methods for ensuring safe operation) to all states that remain in compliance and participate in transparency activities.
Component 2:
Define and universalize guiding principles for human involvement in the use of force.
Humans, not machines, are legal and moral agents in military operations.
It is a human responsibility to ensure that any attack, including one involving autonomous weapons, complies with the laws of war.
Humans responsible for initiating an attack must have sufficient understanding of the weapons, the targets, the environment and the context for use to determine whether that particular attack is lawful.
The attack must be bounded in space, time, target class, and means of attack in order for the determination about the lawfulness of that attack to be meaningful.
Militaries must invest in training, education, doctrine, policies, system design, and human-machine interfaces to ensure that humans remain responsible for attacks.
Component 3:
Develop protocols and/or technological means to mitigate the risk of unintentional escalation due to autonomous systems.
Specific potential measures include:
Developing safe rules for autonomous system behavior when in proximity to adversarial forces to avoid unintentional escalation or signaling. Examples include:
No-first-fire policy, so that autonomous weapons do not initiate hostilities without explicit human authorization.
A human must always be responsible for providing the mission for an autonomous system.
Taking steps to clearly distinguish exercises, patrols, reconnaissance, or other peacetime military operations from attacks in order to limit the possibility of reactions from adversary autonomous systems, such as autonomous air or coastal defenses.
Developing resilient communications links to ensure recallability of autonomous systems. Additionally, militaries should refrain from jamming others’ ability to recall their autonomous systems in order to afford the possibility of human correction in the event of unauthorized behavior.
Component 4:
Develop strategies for preventing proliferation to illicit uses, such as by criminals, terrorists, or rogue states:
Targeted multilateral controls to prevent large-scale sale and transfer of weaponizable robots and related military-specific components for illicit use.
Employ measures to render weaponizable robots less harmful (e.g., geofencing; hard-wired kill switch; onboard control systems largely implemented in unalterable, non-reprogrammable hardware such as application-specific integrated circuits).
Component 5:
Conduct research to improve technologies and human-machine systems to reduce non-combatant harm and ensure IHL-compliance in the use of future weapons, including:
Strategies to promote human moral engagement in decisions about the use of force
Risk assessment for autonomous weapon systems, including the potential for large-scale effects, geopolitical destabilization, accidental escalation, increased instability due to uncertainty about the relative military balance of power, and lowering thresholds to initiating conflict and for violence within conflict
Methodologies for ensuring the reliability and security of autonomous weapon systems
New techniques for verification, validation, explainability, characterization of failure conditions, and behavioral specifications.
About the Authors (in alphabetical order)
Ronald Arkin directs the Mobile Robot Laboratory at Georgia Tech.
Leslie Kaelbling is co-director of the Learning and Intelligent Systems Group at MIT.
Stuart Russell is a professor of computer science and engineering at UC Berkeley.
Dorsa Sadigh is an assistant professor of computer science and of electrical engineering at Stanford.
Paul Scharre directs the Technology and National Security Program at the Center for a New American Security (CNAS).
Bart Selman is a professor of computer science at Cornell.
Toby Walsh is a professor of artificial intelligence at the University of New South Wales (UNSW) Sydney.
The authors would like to thank Max Tegmark for organizing the three-day meeting from which this document was produced.
1 Autonomous Weapons System (AWS): A weapon system that, once activated, can select and engage targets without further intervention by a human operator. BACK TO TEXT↑
2 There is no implication that some authors would not personally support stronger recommendations. BACK TO TEXT↑
3 For ease of use, this working paper will frequently shorten “autonomous weapon system” to “autonomous weapon.” The terms should be treated as synonymous, with the understanding that “weapon” refers to the entire system: sensor, decision-making element, and munition. BACK TO TEXT↑
4 Anti-personnel lethal autonomous weapon system: A weapon system that, once activated, can select and engage dismounted human targets with lethal force and without further intervention by a human operator. BACK TO TEXT↑
5 The authors are not unanimous about this item because of concerns about ease of repurposing for mass-casualty missions targeting unarmed humans. The purpose of the lower limit on explosive payload weight would be to minimize the risk of such repurposing. There is precedent for using explosive weight limit as a mechanism of delineating between anti-personnel and anti-materiel weapons, such as the 1868 St. Petersburg Declaration Renouncing the Use, in Time of War, of Explosive Projectiles Under 400 Grammes Weight. BACK TO TEXT↑ Continue reading
Posted in Human Robots
#436119 How 3D Printing, Vertical Farming, and ...
Food. What we eat, and how we grow it, will be fundamentally transformed in the next decade.
Already, indoor farming is projected to be a US$40.25 billion industry by 2022, with a compound annual growth rate of 9.65 percent. Meanwhile, the food 3D printing industry is expected to grow at an even higher rate, averaging 50 percent annual growth.
And converging exponential technologies—from materials science to AI-driven digital agriculture—are not slowing down. Today’s breakthroughs will soon allow our planet to boost its food production by nearly 70 percent, using a fraction of the real estate and resources, to feed 9 billion by mid-century.
What you consume, how it was grown, and how it will end up in your stomach will all ride the wave of converging exponentials, revolutionizing the most basic of human needs.
Printing Food
3D printing has already had a profound impact on the manufacturing sector. We are now able to print in hundreds of different materials, making anything from toys to houses to organs. However, we are finally seeing the emergence of 3D printers that can print food itself.
Redefine Meat, an Israeli startup, wants to tackle industrial meat production using 3D printers that can generate meat, no animals required. The printer takes in fat, water, and three different plant protein sources, using these ingredients to print a meat fiber matrix with trapped fat and water, thus mimicking the texture and flavor of real meat.
Slated for release in 2020 at a cost of $100,000, their machines are rapidly demonetizing and will begin by targeting clients in industrial-scale meat production.
Anrich3D aims to take this process a step further, 3D printing meals that are customized to your medical records, heath data from your smart wearables, and patterns detected by your sleep trackers. The company plans to use multiple extruders for multi-material printing, allowing them to dispense each ingredient precisely for nutritionally optimized meals. Currently in an R&D phase at the Nanyang Technological University in Singapore, the company hopes to have its first taste tests in 2020.
These are only a few of the many 3D food printing startups springing into existence. The benefits from such innovations are boundless.
Not only will food 3D printing grant consumers control over the ingredients and mixtures they consume, but it is already beginning to enable new innovations in flavor itself, democratizing far healthier meal options in newly customizable cuisine categories.
Vertical Farming
Vertical farming, whereby food is grown in vertical stacks (in skyscrapers and buildings rather than outside in fields), marks a classic case of converging exponential technologies. Over just the past decade, the technology has surged from a handful of early-stage pilots to a full-grown industry.
Today, the average American meal travels 1,500-2,500 miles to get to your plate. As summed up by Worldwatch Institute researcher Brian Halweil, “We are spending far more energy to get food to the table than the energy we get from eating the food.” Additionally, the longer foods are out of the soil, the less nutritious they become, losing on average 45 percent of their nutrition before being consumed.
Yet beyond cutting down on time and transportation losses, vertical farming eliminates a whole host of issues in food production. Relying on hydroponics and aeroponics, vertical farms allows us to grow crops with 90 percent less water than traditional agriculture—which is critical for our increasingly thirsty planet.
Currently, the largest player around is Bay Area-based Plenty Inc. With over $200 million in funding from Softbank, Plenty is taking a smart tech approach to indoor agriculture. Plants grow on 20-foot-high towers, monitored by tens of thousands of cameras and sensors, optimized by big data and machine learning.
This allows the company to pack 40 plants in the space previously occupied by 1. The process also produces yields 350 times greater than outdoor farmland, using less than 1 percent as much water.
And rather than bespoke veggies for the wealthy few, Plenty’s processes allow them to knock 20-35 percent off the costs of traditional grocery stores. To date, Plenty has their home base in South San Francisco, a 100,000 square-foot farm in Kent, Washington, an indoor farm in the United Arab Emirates, and recently started construction on over 300 farms in China.
Another major player is New Jersey-based Aerofarms, which can now grow two million pounds of leafy greens without sunlight or soil.
To do this, Aerofarms leverages AI-controlled LEDs to provide optimized wavelengths of light for each plant. Using aeroponics, the company delivers nutrients by misting them directly onto the plants’ roots—no soil required. Rather, plants are suspended in a growth mesh fabric made from recycled water bottles. And here too, sensors, cameras, and machine learning govern the entire process.
While 50-80 percent of the cost of vertical farming is human labor, autonomous robotics promises to solve that problem. Enter contenders like Iron Ox, a firm that has developed the Angus robot, capable of moving around plant-growing containers.
The writing is on the wall, and traditional agriculture is fast being turned on its head.
Materials Science
In an era where materials science, nanotechnology, and biotechnology are rapidly becoming the same field of study, key advances are enabling us to create healthier, more nutritious, more efficient, and longer-lasting food.
For starters, we are now able to boost the photosynthetic abilities of plants. Using novel techniques to improve a micro-step in the photosynthesis process chain, researchers at UCLA were able to boost tobacco crop yield by 14-20 percent. Meanwhile, the RIPE Project, backed by Bill Gates and run out of the University of Illinois, has matched and improved those numbers.
And to top things off, The University of Essex was even able to improve tobacco yield by 27-47 percent by increasing the levels of protein involved in photo-respiration.
In yet another win for food-related materials science, Santa Barbara-based Apeel Sciences is further tackling the vexing challenge of food waste. Now approaching commercialization, Apeel uses lipids and glycerolipids found in the peels, seeds, and pulps of all fruits and vegetables to create “cutin”—the fatty substance that composes the skin of fruits and prevents them from rapidly spoiling by trapping moisture.
By then spraying fruits with this generated substance, Apeel can preserve foods 60 percent longer using an odorless, tasteless, colorless organic substance.
And stores across the US are already using this method. By leveraging our advancing knowledge of plants and chemistry, materials science is allowing us to produce more food with far longer-lasting freshness and more nutritious value than ever before.
Convergence
With advances in 3D printing, vertical farming, and materials sciences, we can now make food smarter, more productive, and far more resilient.
By the end of the next decade, you should be able to 3D print a fusion cuisine dish from the comfort of your home, using ingredients harvested from vertical farms, with nutritional value optimized by AI and materials science. However, even this picture doesn’t account for all the rapid changes underway in the food industry.
Join me next week for Part 2 of the Future of Food for a discussion on how food production will be transformed, quite literally, from the bottom up.
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Image Credit: Vanessa Bates Ramirez Continue reading
Posted in Human Robots
#435748 Video Friday: This Robot Is Like a ...
Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):
RSS 2019 – June 22-26, 2019 – Freiburg, Germany
Hamlyn Symposium on Medical Robotics – June 23-26, 2019 – London, U.K.
ETH Robotics Summer School – June 27-1, 2019 – Zurich, Switzerland
MARSS 2019 – July 1-5, 2019 – Helsinki, Finland
ICRES 2019 – July 29-30, 2019 – London, U.K.
DARPA SubT Tunnel Circuit – August 15-22, 2019 – Pittsburgh, Pa., USA
Let us know if you have suggestions for next week, and enjoy today’s videos.
It’s been a while since we last spoke to Joe Jones, the inventor of Roomba, about his solar-powered, weed-killing robot, called Tertill, which he was launching as a Kickstarter project. Tertill is now available for purchase (US $300) and is shipping right now.
[ Tertill ]
Usually, we don’t post videos that involve drone use that looks to be either illegal or unsafe. These flights over the protests in Hong Kong are almost certainly both. However, it’s also a unique perspective on the scale of these protests.
[ Team BlackSheep ]
ICYMI: iRobot announced this week that it has acquired Root Robotics.
[ iRobot ]
This Boston Dynamics parody video went viral this week.
The CGI is good but the gratuitous violence—even if it’s against a fake robot—is a bit too much?
This is still our favorite Boston Dynamics parody video:
[ Corridor ]
Biomedical Engineering Department Head Bin He and his team have developed the first-ever successful non-invasive mind-controlled robotic arm to continuously track a computer cursor.
[ CMU ]
Organic chemists, prepare to meet your replacement:
Automated chemical synthesis carries great promises of safety, efficiency and reproducibility for both research and industry laboratories. Current approaches are based on specifically-designed automation systems, which present two major drawbacks: (i) existing apparatus must be modified to be integrated into the automation systems; (ii) such systems are not flexible and would require substantial re-design to handle new reactions or procedures. In this paper, we propose a system based on a robot arm which, by mimicking the motions of human chemists, is able to perform complex chemical reactions without any modifications to the existing setup used by humans. The system is capable of precise liquid handling, mixing, filtering, and is flexible: new skills and procedures could be added with minimum effort. We show that the robot is able to perform a Michael reaction, reaching a yield of 34%, which is comparable to that obtained by a junior chemist (undergraduate student in Chemistry).
[ arXiv ] via [ NTU ]
So yeah, ICRA 2019 was huge and awesome. Here are some brief highlights.
[ Montreal Gazette ]
For about US $5, this drone will deliver raw meat and beer to you if you live on an uninhabited island in Tokyo Bay.
[ Nikkei ]
The Smart Microsystems Lab at Michigan State University has a new version of their Autonomous Surface Craft. It’s autonomous, open source, and awfully hard to sink.
[ SML ]
As drone shows go, this one is pretty good.
[ CCTV ]
Here’s a remote controlled robot shooting stuff with a very large gun.
[ HDT ]
Over a period of three quarters (September 2018 thru May 2019), we’ve had the opportunity to work with five graduating University of Denver students as they brought their idea for a Misty II arm extension to life.
[ Misty Robotics ]
If you wonder how it looks to inspect burners and superheaters of a boiler with an Elios 2, here you are! This inspection was performed by Svenska Elektrod in a peat-fired boiler for Vattenfall in Sweden. Enjoy!
[ Flyability ]
The newest Soft Robotics technology, mGrip mini fingers, made for tight spaces, small packaging, and delicate items, giving limitless opportunities for your applications.
[ Soft Robotics ]
What if legged robots were able to generate dynamic motions in real-time while interacting with a complex environment? Such technology would represent a significant step forward the deployment of legged systems in real world scenarios. This means being able to replace humans in the execution of dangerous tasks and to collaborate with them in industrial applications.
This workshop aims to bring together researchers from all the relevant communities in legged locomotion such as: numerical optimization, machine learning (ML), model predictive control (MPC) and computational geometry in order to chart the most promising methods to address the above-mentioned scientific challenges.
[ Num Opt Wkshp ]
Army researchers teamed with the U.S. Marine Corps to fly and test 3-D printed quadcopter prototypes a the Marine Corps Air Ground Combat Center in 29 Palms, California recently.
[ CCDC ARL ]
Lex Fridman’s Artificial Intelligence podcast featuring Rosalind Picard.
[ AI Podcast ]
In this week’s episode of Robots in Depth, per speaks with Christian Guttmann, executive director of the Nordic AI Artificial Intelligence Institute.
Christian Guttmann talks about AI and wanting to understand intelligence enough to recreate it. Christian has be focusing on AI in healthcare and has recently started to communicate the opportunities and challenges in artificial intelligence to the general public. This is something that the host Per Sjöborg is also very passionate about. We also get to hear about the Nordic AI institute and the work it does to inform all parts of society about AI.
[ Robots in Depth ] Continue reading
Posted in Human Robots
#435575 How an AI Startup Designed a Drug ...
Discovering a new drug can take decades, billions of dollars, and untold man hours from some of the smartest people on the planet. Now a startup says it’s taken a significant step towards speeding the process up using AI.
The typical drug discovery process involves carrying out physical tests on enormous libraries of molecules, and even with the help of robotics it’s an arduous process. The idea of sidestepping this by using computers to virtually screen for promising candidates has been around for decades. But progress has been underwhelming, and it’s still not a major part of commercial pipelines.
Recent advances in deep learning, however, have reignited hopes for the field, and major pharma companies have started tying up with AI-powered drug discovery startups. And now Insilico Medicine has used AI to design a molecule that effectively targets a protein involved in fibrosis—the formation of excess fibrous tissue—in mice in just 46 days.
The platform the company has developed combines two of the hottest sub-fields of AI: the generative adversarial networks, or GANs, which power deepfakes, and reinforcement learning, which is at the heart of the most impressive game-playing AI advances of recent years.
In a paper in Nature Biotechnology, the company’s researchers describe how they trained their model on all the molecules already known to target this protein as well as many other active molecules from various datasets. The model was then used to generate 30,000 candidate molecules.
Unlike most previous efforts, they went a step further and selected the most promising molecules for testing in the lab. The 30,000 candidates were whittled down to just 6 using more conventional drug discovery approaches and were then synthesized in the lab. They were put through increasingly stringent tests, but the leading candidate was found to be effective at targeting the desired protein and behaved as one would hope a drug would.
The authors are clear that the results are just a proof-of-concept, which company CEO Alex Zhavoronkov told Wired stemmed from a challenge set by a pharma partner to design a drug as quickly as possible. But they say they were able to carry out the process faster than traditional methods for a fraction of the cost.
There are some caveats. For a start, the protein being targeted is already very well known and multiple effective drugs exist for it. That gave the company a wealth of data to train their model on, something that isn’t the case for many of the diseases where we urgently need new drugs.
The company’s platform also only targets the very initial stages of the drug discovery process. The authors concede in their paper that the molecules would still take considerable optimization in the lab before they’d be true contenders for clinical trials.
“And that is where you will start to begin to commence to spend the vast piles of money that you will eventually go through in trying to get a drug to market,” writes Derek Lowe in his blog In The Pipeline. The part of the discovery process that the platform tackles represents a tiny fraction of the total cost of drug development, he says.
Nonetheless, the research is a definite advance for virtual screening technology and an important marker of the potential of AI for designing new medicines. Zhavoronkov also told Wired that this research was done more than a year ago, and they’ve since adapted the platform to go after harder drug targets with less data.
And with big pharma companies desperate to slash their ballooning development costs and find treatments for a host of intractable diseases, they can use all the help they can get.
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Posted in Human Robots