Tag Archives: hong
#435793 Tiny Robots Carry Stem Cells Through a ...
Engineers have built microrobots to perform all sorts of tasks in the body, and can now add to that list another key skill: delivering stem cells. In a paper published today in Science Robotics, researchers describe propelling a magnetically-controlled, stem-cell-carrying bot through a live mouse.
Under a rotating magnetic field, the microrobots moved with rolling and corkscrew-style locomotion. The researchers, led by Hongsoo Choi and his team at the Daegu Gyeongbuk Institute of Science & Technology (DGIST), in South Korea, also demonstrated their bot’s moves in slices of mouse brain, in blood vessels isolated from rat brains, and in a multi-organ-on-a chip.
The invention provides an alternative way to deliver stem cells, which are increasingly important in medicine. Such cells can be coaxed into becoming nearly any kind of cell, making them great candidates for treating neurodegenerative disorders such as Alzheimer’s.
But delivering stem cells typically requires an injection with a needle, which lowers the survival rate of the stem cells, and limits their reach in the body. Microrobots, however, have the potential to deliver stem cells to precise, hard-to-reach areas, with less damage to surrounding tissue, and better survival rates, says Jin-young Kim, a principle investigator at DGIST-ETH Microrobotics Research Center, and an author on the paper.
The virtues of microrobots have inspired several research groups to propose and test different designs in simple conditions, such as microfluidic channels and other static environments. A group out of Hong Kong last year described a burr-shaped bot that carried cells through live, transparent zebrafish.
The new research presents a magnetically-actuated microrobot that successfully carried stem cells through a live mouse. In additional experiments, the cells, which had differentiated into brain cells such as astrocytes, oligodendrocytes, and neurons, transferred to microtissues on the multi-organ-on-a-chip. Taken together, the proof-of-concept experiments demonstrate the potential for microrobots to be used in human stem cell therapy, says Kim.
The team fabricated the robots with 3D laser lithography, and designed them in two shapes: spherical and helical. Using a rotating magnetic field, the scientists navigated the spherical-shaped bots with a rolling motion, and the helical bots with a corkscrew motion. These styles of locomotion proved more efficient than that from a simple pulling force, and were more suitable for use in biological fluids, the scientists reported.
The big challenge in navigating microbots in a live animal (or human body) is being able to see them in real time. Imaging with fMRI doesn’t work, because the magnetic fields interfere with the system. “To precisely control microbots in vivo, it is important to actually see them as they move,” the authors wrote in their paper.
That wasn’t possible during experiments in a live mouse, so the researchers had to check the location of the microrobots before and after the experiments using an optical tomography system called IVIS. They also had to resort to using a pulling force with a permanent magnet to navigate the microrobots inside the mouse, due to the limitations of the IVIS system.
Kim says he and his colleagues are developing imaging systems that will enable them to view in real time the locomotion of their microrobots in live animals. Continue reading
#435748 Video Friday: This Robot Is Like a ...
Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):
RSS 2019 – June 22-26, 2019 – Freiburg, Germany
Hamlyn Symposium on Medical Robotics – June 23-26, 2019 – London, U.K.
ETH Robotics Summer School – June 27-1, 2019 – Zurich, Switzerland
MARSS 2019 – July 1-5, 2019 – Helsinki, Finland
ICRES 2019 – July 29-30, 2019 – London, U.K.
DARPA SubT Tunnel Circuit – August 15-22, 2019 – Pittsburgh, Pa., USA
Let us know if you have suggestions for next week, and enjoy today’s videos.
It’s been a while since we last spoke to Joe Jones, the inventor of Roomba, about his solar-powered, weed-killing robot, called Tertill, which he was launching as a Kickstarter project. Tertill is now available for purchase (US $300) and is shipping right now.
[ Tertill ]
Usually, we don’t post videos that involve drone use that looks to be either illegal or unsafe. These flights over the protests in Hong Kong are almost certainly both. However, it’s also a unique perspective on the scale of these protests.
[ Team BlackSheep ]
ICYMI: iRobot announced this week that it has acquired Root Robotics.
[ iRobot ]
This Boston Dynamics parody video went viral this week.
The CGI is good but the gratuitous violence—even if it’s against a fake robot—is a bit too much?
This is still our favorite Boston Dynamics parody video:
[ Corridor ]
Biomedical Engineering Department Head Bin He and his team have developed the first-ever successful non-invasive mind-controlled robotic arm to continuously track a computer cursor.
[ CMU ]
Organic chemists, prepare to meet your replacement:
Automated chemical synthesis carries great promises of safety, efficiency and reproducibility for both research and industry laboratories. Current approaches are based on specifically-designed automation systems, which present two major drawbacks: (i) existing apparatus must be modified to be integrated into the automation systems; (ii) such systems are not flexible and would require substantial re-design to handle new reactions or procedures. In this paper, we propose a system based on a robot arm which, by mimicking the motions of human chemists, is able to perform complex chemical reactions without any modifications to the existing setup used by humans. The system is capable of precise liquid handling, mixing, filtering, and is flexible: new skills and procedures could be added with minimum effort. We show that the robot is able to perform a Michael reaction, reaching a yield of 34%, which is comparable to that obtained by a junior chemist (undergraduate student in Chemistry).
[ arXiv ] via [ NTU ]
So yeah, ICRA 2019 was huge and awesome. Here are some brief highlights.
[ Montreal Gazette ]
For about US $5, this drone will deliver raw meat and beer to you if you live on an uninhabited island in Tokyo Bay.
[ Nikkei ]
The Smart Microsystems Lab at Michigan State University has a new version of their Autonomous Surface Craft. It’s autonomous, open source, and awfully hard to sink.
[ SML ]
As drone shows go, this one is pretty good.
[ CCTV ]
Here’s a remote controlled robot shooting stuff with a very large gun.
[ HDT ]
Over a period of three quarters (September 2018 thru May 2019), we’ve had the opportunity to work with five graduating University of Denver students as they brought their idea for a Misty II arm extension to life.
[ Misty Robotics ]
If you wonder how it looks to inspect burners and superheaters of a boiler with an Elios 2, here you are! This inspection was performed by Svenska Elektrod in a peat-fired boiler for Vattenfall in Sweden. Enjoy!
[ Flyability ]
The newest Soft Robotics technology, mGrip mini fingers, made for tight spaces, small packaging, and delicate items, giving limitless opportunities for your applications.
[ Soft Robotics ]
What if legged robots were able to generate dynamic motions in real-time while interacting with a complex environment? Such technology would represent a significant step forward the deployment of legged systems in real world scenarios. This means being able to replace humans in the execution of dangerous tasks and to collaborate with them in industrial applications.
This workshop aims to bring together researchers from all the relevant communities in legged locomotion such as: numerical optimization, machine learning (ML), model predictive control (MPC) and computational geometry in order to chart the most promising methods to address the above-mentioned scientific challenges.
[ Num Opt Wkshp ]
Army researchers teamed with the U.S. Marine Corps to fly and test 3-D printed quadcopter prototypes a the Marine Corps Air Ground Combat Center in 29 Palms, California recently.
[ CCDC ARL ]
Lex Fridman’s Artificial Intelligence podcast featuring Rosalind Picard.
[ AI Podcast ]
In this week’s episode of Robots in Depth, per speaks with Christian Guttmann, executive director of the Nordic AI Artificial Intelligence Institute.
Christian Guttmann talks about AI and wanting to understand intelligence enough to recreate it. Christian has be focusing on AI in healthcare and has recently started to communicate the opportunities and challenges in artificial intelligence to the general public. This is something that the host Per Sjöborg is also very passionate about. We also get to hear about the Nordic AI institute and the work it does to inform all parts of society about AI.
[ Robots in Depth ] Continue reading
#435579 RoMeLa’s Newest Robot Is a ...
A few years ago, we wrote about NABiRoS, a bipedal robot from Dennis Hong’s Robotics & Mechanisms Laboratory (RoMeLa) at UCLA. Unlike pretty much any other biped we’d ever seen, NABiRoS had a unique kinematic configuration that had it using its two legs to walk sideways, which offered some surprising advantages.
As it turns out, bipeds aren’t the only robots that can potentially benefit from a bit of a kinematic rethink. RoMeLa has redesigned quadrupedal robots too—rather than model them after a quadrupedal animal like a dog or a horse, RoMeLa’s ALPHRED robots use four legs arranged symmetrically around the body of the robot, allowing it to walk, run, hop, and jump, as well as manipulate and carry objects, karate chop through boards, and even roller skate on its butt. This robot can do it all.
Impressive, right? This is ALPHRED 2, and its predecessor, the original ALPHRED, was introduced at IROS 2018. Both ALPHREDs are axisymmetric about the vertical axis, meaning that they don’t have a front or a back and are perfectly happy to walk in any direction you like. Traditional quadrupeds like Spot or Laikago can also move sideways and backwards, but their leg arrangement makes them more efficient at moving in one particular direction, and also results in some curious compromises like a preference for going down stairs backwards. ANYmal is a bit more flexible in that it can reverse its knees, but it’s still got that traditional quadrupedal two-by-two configuration.
ALPHRED 2’s four symmetrical limbs can be used for a whole bunch of stuff. It can do quadrupedal walking and running, and it’s able to reach stable speeds of up to 1.5 m/s. If you want bipedal walking, it can do that NABiRoS-style, although it’s still a bit fragile at the moment. Using two legs for walking leaves two legs free, and those legs can turn into arms. A tripedal compromise configuration, with three legs and one arm, is more stable and allows the robot to do things like push buttons, open doors, and destroy property. And thanks to passive wheels under its body, ALPHRED 2 can use its limbs to quickly and efficiently skate around:
The impressive performance of the robot comes courtesy of a custom actuator that RoMeLa designed specifically for dynamic legged locomotion. They call it BEAR, or Back-Drivable Electromechanical Actuator for Robots. These are optionally liquid-cooled motors capable of proprioceptive sensing, consisting of a DC motor, a single stage 10:1 planetary gearbox, and channels through the back of the housing that coolant can be pumped through. The actuators have a peak torque of 32 Nm, and a continuous torque of about 8 Nm with passive air cooling. With liquid cooling, the continuous torque jumps to about 21 Nm. And in the videos above, ALPHRED 2 isn’t even running the liquid cooling system, suggesting that it’s capable of much higher sustained performance.
Photo: RoMeLa
Using two legs for walking leaves two legs free, and those legs can turn into arms.
RoMeLa has produced a bunch of very creative robots, and we appreciate that they also seem to produce a bunch of very creative demos showing why their unusual approaches are in fact (at least in some specific cases) somewhat practical. With the recent interest in highly dynamic robots that can be reliably useful in environments infested with humans, we can’t wait to see what kinds of exciting tricks the next (presumably liquid-cooled) version will be able to do.
[ RoMeLa ] Continue reading