Tag Archives: health

#433278 Outdated Evolution: Updating Our ...

What happens when evolution shapes an animal for tribes of 150 primitive individuals living in a chaotic jungle, and then suddenly that animal finds itself living with millions of others in an engineered metropolis, their pockets all bulging with devices of godlike power?

The result, it seems, is a modern era of tension where archaic forms of governance struggle to keep up with the technological advances of their citizenry, where governmental policies act like constraining bottlenecks rather than spearheads of progress.

Simply put, our governments have failed to adapt to disruptive technologies. And if we are to regain our stability moving forward into a future of even greater disruption, it’s imperative that we understand the issues that got us into this situation and what kind of solutions we can engineer to overcome our governmental weaknesses.

Hierarchy vs. Technological Decentralization
Many of the greatest issues our governments face today come from humanity’s biologically-hardwired desire for centralized hierarchies. This innate proclivity towards building and navigating systems of status and rank were evolutionary gifts handed down to us by our ape ancestors, where each member of a community had a mental map of their social hierarchy. Their nervous systems behaved differently depending on their rank in this hierarchy, influencing their interactions in a way that ensured only the most competent ape would rise to the top to gain access to the best food and mates.

As humanity emerged and discovered the power of language, we continued this practice by ensuring that those at the top of the hierarchies, those with the greatest education and access to information, were the dominant decision-makers for our communities.

However, this kind of structured chain of power is only necessary if we’re operating in conditions of scarcity. But resources, including information, are no longer scarce.

It’s estimated that more than two-thirds of adults in the world now own a smartphone, giving the average citizen the same access to the world’s information as the leaders of our governments. And with global poverty falling from 35.5 percent to 10.9 percent over the last 25 years, our younger generations are growing up seeing automation and abundance as a likely default, where innovations like solar energy, lab-grown meat, and 3D printing are expected to become commonplace.

It’s awareness of this paradigm shift that has empowered the recent rise of decentralization. As information and access to resources become ubiquitous, there is noticeably less need for our inefficient and bureaucratic hierarchies.

For example, if blockchain can prove its feasibility for large-scale systems, it can be used to update and upgrade numerous applications to a decentralized model, including currency and voting. Such innovations would lower the risk of failing banks collapsing the economy like they did in 2008, as well as prevent corrupt politicians from using gerrymandering and long queues at polling stations to deter voter participation.

Of course, technology isn’t a magic wand that should be implemented carelessly. Facebook’s “move fast and break things” approach might have very possibly broken American democracy in 2016, as social media played on some of the worst tendencies humanity can operate on during an election: fear and hostility.

But if decentralized technology, like blockchain’s public ledgers, can continue to spread a sense of security and transparency throughout society, perhaps we can begin to quiet that paranoia and hyper-vigilance our brains evolved to cope with living as apes in dangerous jungles. By decentralizing our power structures, we take away the channels our outdated biological behaviors might use to enact social dominance and manipulation.

The peace of mind this creates helps to reestablish trust in our communities and in our governments. And with trust in the government increased, it’s likely we’ll see our next issue corrected.

From Business and Law to Science and Technology
A study found that 59 percent of US presidents, 68 percent of vice presidents, and 78 percent of secretaries of state were lawyers by education and occupation. That’s more than one out of every two people in the most powerful positions in the American government restricted to a field dedicated to convincing other people (judges) their perspective is true, even if they lack evidence.

And so the scientific method became less important than semantics to our leaders.

Similarly, of the 535 individuals in the American congress, only 24 hold a PhD, only 2 of which are in a STEM field. And so far, it’s not getting better: Trump is the first president since WWII not to name a science advisor.

But if we can use technologies like blockchain to increase transparency, efficiency, and trust in the government, then the upcoming generations who understand decentralization, abundance, and exponential technologies might feel inspired enough to run for government positions. This helps solve that common problem where the smartest and most altruistic people tend to avoid government positions because they don’t want to play the semantic and deceitful game of politics.

By changing this narrative, our governments can begin to fill with techno-progressive individuals who actually understand the technologies that are rapidly reshaping our reality. And this influence of expertise is going to be crucial as our governments are forced to restructure and create new policies to accommodate the incoming disruption.

Clearing Regulations to Begin Safe Experimentation
As exponential technologies become more ubiquitous, we’re likely going to see young kids and garage tinkerers creating powerful AIs and altering genetics thanks to tools like CRISPR and free virtual reality tutorials.

This easy accessibility to such powerful technology means unexpected and rapid progress can occur almost overnight, quickly overwhelming our government’s regulatory systems.

Uber and Airbnb are two of the best examples of our government’s inability to keep up with such technology, both companies achieving market dominance before regulators were even able to consider how to handle them. And when a government has decided against them, they often still continue to operate because people simply choose to keep using the apps.

Luckily, this kind of disruption hasn’t yet posed a major existential threat. But this will change when we see companies begin developing cyborg body parts, brain-computer interfaces, nanobot health injectors, and at-home genetic engineering kits.

For this reason, it’s crucial that we have experts who understand how to update our regulations to be as flexible as is necessary to ensure we don’t create black market conditions like we’ve done with drugs. It’s better to have safe and monitored experimentation, rather than forcing individuals into seedy communities using unsafe products.

Survival of the Most Adaptable
If we hope to be an animal that survives our changing environment, we have to adapt. We cannot cling to the behaviors and systems formed thousands of years ago. We must instead acknowledge that we now exist in an ecosystem of disruptive technology, and we must evolve and update our governments if they’re going to be capable of navigating these transformative impacts.

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Posted in Human Robots

#432691 Is the Secret to Significantly Longer ...

Once upon a time, a powerful Sumerian king named Gilgamesh went on a quest, as such characters often do in these stories of myth and legend. Gilgamesh had witnessed the death of his best friend, Enkidu, and, fearing a similar fate, went in search of immortality. The great king failed to find the secret of eternal life but took solace that his deeds would live well beyond his mortal years.

Fast-forward four thousand years, give or take a century, and Gilgamesh (as famous as any B-list celebrity today, despite the passage of time) would probably be heartened to learn that many others have taken up his search for longevity. Today, though, instead of battling epic monsters and the machinations of fickle gods, those seeking to enhance and extend life are cutting-edge scientists and visionary entrepreneurs who are helping unlock the secrets of human biology.

Chief among them is Aubrey de Grey, a biomedical gerontologist who founded the SENS Research Foundation, a Silicon Valley-based research organization that seeks to advance the application of regenerative medicine to age-related diseases. SENS stands for Strategies for Engineered Negligible Senescence, a term coined by de Grey to describe a broad array (seven, to be precise) of medical interventions that attempt to repair or prevent different types of molecular and cellular damage that eventually lead to age-related diseases like cancer and Alzheimer’s.

Many of the strategies focus on senescent cells, which accumulate in tissues and organs as people age. Not quite dead, senescent cells stop dividing but are still metabolically active, spewing out all sorts of proteins and other molecules that can cause inflammation and other problems. In a young body, that’s usually not a problem (and probably part of general biological maintenance), as a healthy immune system can go to work to put out most fires.

However, as we age, senescent cells continue to accumulate, and at some point the immune system retires from fire watch. Welcome to old age.

Of Mice and Men
Researchers like de Grey believe that treating the cellular underpinnings of aging could not only prevent disease but significantly extend human lifespans. How long? Well, if you’re talking to de Grey, Biblical proportions—on the order of centuries.

De Grey says that science has made great strides toward that end in the last 15 years, such as the ability to copy mitochondrial DNA to the nucleus. Mitochondria serve as the power plant of the cell but are highly susceptible to mutations that lead to cellular degeneration. Copying the mitochondrial DNA into the nucleus would help protect it from damage.

Another achievement occurred about six years ago when scientists first figured out how to kill senescent cells. That discovery led to a spate of new experiments in mice indicating that removing these ticking-time-bomb cells prevented disease and even extended their lifespans. Now the anti-aging therapy is about to be tested in humans.

“As for the next few years, I think the stream of advances is likely to become a flood—once the first steps are made, things get progressively easier and faster,” de Grey tells Singularity Hub. “I think there’s a good chance that we will achieve really dramatic rejuvenation of mice within only six to eight years: maybe taking middle-aged mice and doubling their remaining lifespan, which is an order of magnitude more than can be done today.”

Not Horsing Around
Richard G.A. Faragher, a professor of biogerontology at the University of Brighton in the United Kingdom, recently made discoveries in the lab regarding the rejuvenation of senescent cells with chemical compounds found in foods like chocolate and red wine. He hopes to apply his findings to an animal model in the future—in this case,horses.

“We have been very fortunate in receiving some funding from an animal welfare charity to look at potential treatments for older horses,” he explains to Singularity Hub in an email. “I think this is a great idea. Many aspects of the physiology we are studying are common between horses and humans.”

What Faragher and his colleagues demonstrated in a paper published in BMC Cell Biology last year was that resveralogues, chemicals based on resveratrol, were able to reactivate a protein called a splicing factor that is involved in gene regulation. Within hours, the chemicals caused the cells to rejuvenate and start dividing like younger cells.

“If treatments work in our old pony systems, then I am sure they could be translated into clinical trials in humans,” Faragher says. “How long is purely a matter of money. Given suitable funding, I would hope to see a trial within five years.”

Show Them the Money
Faragher argues that the recent breakthroughs aren’t because a result of emerging technologies like artificial intelligence or the gene-editing tool CRISPR, but a paradigm shift in how scientists understand the underpinnings of cellular aging. Solving the “aging problem” isn’t a question of technology but of money, he says.

“Frankly, when AI and CRISPR have removed cystic fibrosis, Duchenne muscular dystrophy or Gaucher syndrome, I’ll be much more willing to hear tales of amazing progress. Go fix a single, highly penetrant genetic disease in the population using this flashy stuff and then we’ll talk,” he says. “My faith resides in the most potent technological development of all: money.”

De Grey is less flippant about the role that technology will play in the quest to defeat aging. AI, CRISPR, protein engineering, advances in stem cell therapies, and immune system engineering—all will have a part.

“There is not really anything distinctive about the ways in which these technologies will contribute,” he says. “What’s distinctive is that we will need all of these technologies, because there are so many different types of damage to repair and they each require different tricks.”

It’s in the Blood
A startup in the San Francisco Bay Area believes machines can play a big role in discovering the right combination of factors that lead to longer and healthier lives—and then develop drugs that exploit those findings.

BioAge Labs raised nearly $11 million last year for its machine learning platform that crunches big data sets to find blood factors, such as proteins or metabolites, that are tied to a person’s underlying biological age. The startup claims that these factors can predict how long a person will live.

“Our interest in this comes out of research into parabiosis, where joining the circulatory systems of old and young mice—so that they share the same blood—has been demonstrated to make old mice healthier and more robust,” Dr. Eric Morgen, chief medical officer at BioAge, tells Singularity Hub.

Based on that idea, he explains, it should be possible to alter those good or bad factors to produce a rejuvenating effect.

“Our main focus at BioAge is to identify these types of factors in our human cohort data, characterize the important molecular pathways they are involved in, and then drug those pathways,” he says. “This is a really hard problem, and we use machine learning to mine these complex datasets to determine which individual factors and molecular pathways best reflect biological age.”

Saving for the Future
Of course, there’s no telling when any of these anti-aging therapies will come to market. That’s why Forever Labs, a biotechnology startup out of Ann Arbor, Michigan, wants your stem cells now. The company offers a service to cryogenically freeze stem cells taken from bone marrow.

The theory behind the procedure, according to Forever Labs CEO Steven Clausnitzer, is based on research showing that stem cells may be a key component for repairing cellular damage. That’s because stem cells can develop into many different cell types and can divide endlessly to replenish other cells. Clausnitzer notes that there are upwards of a thousand clinical studies looking at using stem cells to treat age-related conditions such as cardiovascular disease.

However, stem cells come with their own expiration date, which usually coincides with the age that most people start experiencing serious health problems. Stem cells harvested from bone marrow at a younger age can potentially provide a therapeutic resource in the future.

“We believe strongly that by having access to your own best possible selves, you’re going to be well positioned to lead healthier, longer lives,” he tells Singularity Hub.

“There’s a compelling argument to be made that if you started to maintain the bone marrow population, the amount of nuclear cells in your bone marrow, and to re-up them so that they aren’t declining with age, it stands to reason that you could absolutely mitigate things like cardiovascular disease and stroke and Alzheimer’s,” he adds.

Clausnitzer notes that the stored stem cells can be used today in developing therapies to treat chronic conditions such as osteoarthritis. However, the more exciting prospect—and the reason he put his own 38-year-old stem cells on ice—is that he believes future stem cell therapies can help stave off the ravages of age-related disease.

“I can start reintroducing them not to treat age-related disease but to treat the decline in the stem-cell niche itself, so that I don’t ever get an age-related disease,” he says. “I don’t think that it equates to immortality, but it certainly is a step in that direction.”

Indecisive on Immortality
The societal implications of a longer-living human species are a guessing game at this point. We do know that by mid-century, the global population of those aged 65 and older will reach 1.6 billion, while those older than 80 will hit nearly 450 million, according to the National Academies of Science. If many of those people could enjoy healthy lives in their twilight years, an enormous medical cost could be avoided.

Faragher is certainly working toward a future where human health is ubiquitous. Human immortality is another question entirely.

“The longer lifespans become, the more heavily we may need to control birth rates and thus we may have fewer new minds. This could have a heavy ‘opportunity cost’ in terms of progress,” he says.

And does anyone truly want to live forever?

“There have been happy moments in my life but I have also suffered some traumatic disappointments. No [drug] will wash those experiences out of me,” Faragher says. “I no longer view my future with unqualified enthusiasm, and I do not think I am the only middle-aged man to feel that way. I don’t think it is an accident that so many ‘immortalists’ are young.

“They should be careful what they wish for.”

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Posted in Human Robots

#432539 10 Amazing Things You Can Learn From ...

Hardly a day goes by without a research study or article published talking sh*t—or more precisely, talking about the gut microbiome. When it comes to cutting-edge innovations in medicine, all signs point to the microbiome. Maybe we should have listened to Hippocrates: “All disease begins in the gut.”

Your microbiome is mostly located in your gut and contains trillions of little guys and gals called microbes. If you want to optimize your health, biohack your body, make progress against chronic disease, or know which foods are right for you—almost all of this information can be found in your microbiome.

My company, Viome, offers technology to measure your microscopic organisms and their behavior at a molecular level. Think of it as the Instagram of your inner world. A snapshot of what’s happening inside your body. New research about the microbiome is changing our understanding of who we are as humans and how the human body functions.

It turns out the microbiome may be mission control for your body and mind. Your healthy microbiome is part best friend, part power converter, part engine, and part pharmacist. At Viome, we’re working to analyze these microbial functions and recommend a list of personalized food and supplements to keep these internal complex machines in a finely tuned balance.

We now have more information than ever before about what your microbiome is doing, and it’s going to help you and the rest of the world do a whole lot better. The new insights emerging from microbiome research are changing our perception of what keeps us healthy and what makes us sick. This new understanding of the microbiome activities may put an end to conflicting food advice and make fad diets a thing of the past.

What are these new insights showing us? The information is nothing short of mind-blowing. The value of your poop just got an upgrade.

Here are some of the amazing things we’ve learned from our work at Viome.

1. Was Popeye wrong? Why “health food” isn’t necessarily healthy.
Each week there is a new fad diet released, discussed, and followed. The newest “research” shows that this is now the superfood to eat for everyone. But, too often, the fad diet is just a regurgitation of what worked for one person and shouldn’t be followed by everyone else.

For example, we’ve been told to eat our greens and that greens and nuts are “anti-inflammatory,” but this is actually not always true. Spinach, bran, rhubarb, beets, nuts, and nut butters all contain oxalate. We now know that oxalate-containing food can be harmful, unless you have the microbes present that can metabolize it into a non-harmful substance.

30% of Viome customers do not have the microbes to metabolize oxalates properly. In other words, “healthy foods” like spinach are actually not healthy for these people.

Looks like not everyone should follow Popeye’s food plan.

2. Aren’t foods containing “antioxidants” always good for everyone?
Just like oxalates, polyphenols in foods are usually considered very healthy, but unless you have microbes that utilize specific polyphenols, you may not get full benefit from them. One example is a substance found in these foods called ellagic acid. We can detect if your microbiome is metabolizing ellagic acid and converting it into urolithin A. It is only the urolithin A that has anti-inflammatory and antioxidant effects. Without the microbes to do this conversion you will not benefit from the ellagic acid in foods.

Examples: Walnuts, raspberries, pomegranate, blackberries, pecans, and cranberries all contain ellagic acid.

We have analyzed tens of thousands of people, and only about 50% of the people actually benefit from eating more foods containing ellagic acid.

3. You’re probably eating too much protein (and it may be causing inflammation).
When you think high-protein diet, you think paleo, keto, and high-performance diets.

Protein is considered good for you. It helps build muscle and provide energy—but if you eat too much, it can cause inflammation and decrease longevity.

We can analyze the activity of your microbiome to determine if you are eating too much protein that feeds protein-fermenting bacteria like Alistipes putredinis and Tannerella forsythia, and if these organisms are producing harmful substances such as ammonia, hydrogen sulfide, p-cresol, or putrescine. These substances can damage your gut lining and lead to things like leaky gut.

4. Something’s fishy. Are “healthy foods” causing heart disease?
Choline in certain foods can get converted by bacteria into a substance called trimethylamine (TMA) that is associated with heart disease when it gets absorbed into your body and converted to TMAO. However, TMA conversion doesn’t happen in individuals without these types of bacteria in their microbiome.

We can see the TMA production pathways and many of the gammaproteobacteria that do this conversion.

What foods contain choline? Liver, salmon, chickpeas, split peas, eggs, navy beans, peanuts, and many others.

Before you decide to go full-on pescatarian or paleo, you may want to check if your microbiome is producing TMA with that salmon or steak.

5. Hold up, Iron Man. We can see inflammation from too much iron.
Minerals like iron in your food can, in certain inflammatory microbial environments, promote growth of pathogens like Esherichia, Shigella, and Salmonella.

Maybe it wasn’t just that raw chicken that gave you food poisoning, but your toxic microbiome that made you sick.

On the other hand, when you don’t have enough iron, you could become anemic leading to weakness and shortness of breath.

So, just like Iron Man, it’s about finding your balance so that you can fly.

6. Are you anxious or stressed? Your poop will tell you.
Our gut and brain are connected via the vagus nerve. A large majority of neurotransmitters are either produced or consumed by our microbiome. In fact, some 90% of all serotonin (a feel-good neurotransmitter) is produced by your gut microbiome and not by your brain.

When you have a toxic microbiome that’s producing a large amount of toxins like hydrogen sulfide, the lining of your gut starts to deteriorate into what’s known as leaky gut. Think of leaky gut as your gut not having healthy borders or boundaries. And when this happens, all kinds of disease can emerge. When the barrier of the gut breaks down, it starts a chain reaction causing low-grade chronic inflammation—which has been identified as a potential source of depression and higher levels of anxiety, in addition to many other chronic diseases.

We’re not saying you shouldn’t meditate, but if you want to get the most out of your meditation and really reduce your stress levels, make sure you are eating the right food that promotes a healthy microbiome.

7. Your microbiome is better than Red Bull.
If you want more energy, get your microbiome back into balance.

No you don’t need three pots of coffee to keep you going, you just need a balanced microbiome.

Your microbiome is responsible for calorie extraction, or creating energy, through pathways such as the Tricarboxylic acid cycle. Our bodies depend on the energy that our microbiome produces.

How much energy we get from our food is dependent on how efficient our microbiome is at converting the food into energy. High-performing microbiomes are excellent at converting food into energy. This is great when you are an athlete and need the extra energy, but if you don’t use up the energy it may be the source of some of those unwanted pounds.

If the microbes can’t or won’t metabolize the glucose (sugar) that you eat, it will be stored as fat. If the microbes are extracting too many calories from your food or producing lipopolysaccharides (LPS) and causing metabolic endotoxemia leading to activation of toll-like receptors and insulin resistance you may end up storing what you eat as fat.

Think of your microbiome as Doc Brown’s car from the future—it can take pretty much anything and turn it into fuel if it’s strong and resilient enough.

8. We can see your joint pain in your poop.
Got joint pain? Your microbiome can tell you why.

Lipopolysaccharide (LPS) is a key pro-inflammatory molecule made by some of your microbes. If your microbes are making too much LPS, it can wreak havoc on your immune system by putting it into overdrive. When your immune system goes on the warpath there is often collateral damage to your joints and other body parts.

Perhaps balancing your microbiome is a better solution than reaching for the glucosamine. Think of your microbiome as the top general of your immune army. It puts your immune system through basic training and determines when it goes to war.

Ideally, your immune system wins the quick battle and gets some rest, but sometimes if your microbiome keeps it on constant high alert it becomes a long, drawn-out war resulting in chronic inflammation and chronic diseases.

Are you really “getting older” or is your microbiome just making you “feel” older because it keeps giving warnings to your immune system ultimately leading to chronic pain?

Before you throw in the towel on your favorite activities, check your microbiome. And, if you have anything with “itis” in it, it’s possible that when you balance your microbiome the inflammation from your “itis” will be reduced.

9. Your gut is doing the talking for your mouth.
When you have low stomach acid, your mouth bacteria makes it down to your GI tract.

Stomach acid is there to protect you from the bacteria in your mouth and the parasites and fungi that are in your food. If you don’t have enough of it, the bacteria in your mouth will invade your gut. This invasion is associated with and a risk factor for autoimmune disease and inflammation in the gut.

We are learning that low stomach acid is perhaps one of the major causes of chronic disease. This stomach acid is essential to kill mouth bacteria and help us digest our food.

What kinds of things cause low stomach acid? Stress and antacids like Nexium, Zantac, and Prilosec.

10. Carbs can be protein precursors.
Rejoice! Perhaps carbs aren’t as bad as we thought (as long as your microbiome is up to the task). We can see if some of the starches you eat can be made into amino acids by the microbiome.

Our microbiome makes 20% of our branched-chain amino acids (BCAAs) for us, and it will adapt to make these vital BCAAs for us in almost any way it can.

Essentially, your microbiome is hooking up carbons and hydrogens into different formulations of BCAAs, depending on what you feed it. The microbiome is excellent at adapting and pivoting based on the food you feed it and the environment that it’s in.

So, good news: Carbs are protein precursors, as long as you have the right microbiome.

Stop Talking Sh*t Now
Your microbiome is a world class entrepreneur that can take low-grade sources of food and turn them into valuable and useable energy.

You have a best friend and confidant within you that is working wonders to make sure you have energy and that all of your needs are met.

And, just like a best friend, if you take great care of your microbiome, it will take great care of you.

Given the research emerging daily about the microbiome and its importance on your quality of life, prioritizing the health of your microbiome is essential.

When you have a healthy microbiome, you’ll have a healthy life.

It’s now clear that some of the greatest insights for your health will come from your poop.

It’s time to stop talking sh*t and get your sh*t together. Your life may depend on it.

Viome can help you identify what your microbiome is actually doing. The combination of Viome’s metatranscriptomic technology and cutting-edge artificial intelligence is paving a brand new path forward for microbiome health.

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Posted in Human Robots

#432519 Robot Cities: Three Urban Prototypes for ...

Before I started working on real-world robots, I wrote about their fictional and historical ancestors. This isn’t so far removed from what I do now. In factories, labs, and of course science fiction, imaginary robots keep fueling our imagination about artificial humans and autonomous machines.

Real-world robots remain surprisingly dysfunctional, although they are steadily infiltrating urban areas across the globe. This fourth industrial revolution driven by robots is shaping urban spaces and urban life in response to opportunities and challenges in economic, social, political, and healthcare domains. Our cities are becoming too big for humans to manage.

Good city governance enables and maintains smooth flow of things, data, and people. These include public services, traffic, and delivery services. Long queues in hospitals and banks imply poor management. Traffic congestion demonstrates that roads and traffic systems are inadequate. Goods that we increasingly order online don’t arrive fast enough. And the WiFi often fails our 24/7 digital needs. In sum, urban life, characterized by environmental pollution, speedy life, traffic congestion, connectivity and increased consumption, needs robotic solutions—or so we are led to believe.

Is this what the future holds? Image Credit: Photobank gallery / Shutterstock.com
In the past five years, national governments have started to see automation as the key to (better) urban futures. Many cities are becoming test beds for national and local governments for experimenting with robots in social spaces, where robots have both practical purpose (to facilitate everyday life) and a very symbolic role (to demonstrate good city governance). Whether through autonomous cars, automated pharmacists, service robots in local stores, or autonomous drones delivering Amazon parcels, cities are being automated at a steady pace.

Many large cities (Seoul, Tokyo, Shenzhen, Singapore, Dubai, London, San Francisco) serve as test beds for autonomous vehicle trials in a competitive race to develop “self-driving” cars. Automated ports and warehouses are also increasingly automated and robotized. Testing of delivery robots and drones is gathering pace beyond the warehouse gates. Automated control systems are monitoring, regulating and optimizing traffic flows. Automated vertical farms are innovating production of food in “non-agricultural” urban areas around the world. New mobile health technologies carry promise of healthcare “beyond the hospital.” Social robots in many guises—from police officers to restaurant waiters—are appearing in urban public and commercial spaces.

Vertical indoor farm. Image Credit: Aisyaqilumaranas / Shutterstock.com
As these examples show, urban automation is taking place in fits and starts, ignoring some areas and racing ahead in others. But as yet, no one seems to be taking account of all of these various and interconnected developments. So, how are we to forecast our cities of the future? Only a broad view allows us to do this. To give a sense, here are three examples: Tokyo, Dubai, and Singapore.

Tokyo
Currently preparing to host the Olympics 2020, Japan’s government also plans to use the event to showcase many new robotic technologies. Tokyo is therefore becoming an urban living lab. The institution in charge is the Robot Revolution Realization Council, established in 2014 by the government of Japan.

Tokyo: city of the future. Image Credit: ESB Professional / Shutterstock.com
The main objectives of Japan’s robotization are economic reinvigoration, cultural branding, and international demonstration. In line with this, the Olympics will be used to introduce and influence global technology trajectories. In the government’s vision for the Olympics, robot taxis transport tourists across the city, smart wheelchairs greet Paralympians at the airport, ubiquitous service robots greet customers in 20-plus languages, and interactively augmented foreigners speak with the local population in Japanese.

Tokyo shows us what the process of state-controlled creation of a robotic city looks like.

Singapore
Singapore, on the other hand, is a “smart city.” Its government is experimenting with robots with a different objective: as physical extensions of existing systems to improve management and control of the city.

In Singapore, the techno-futuristic national narrative sees robots and automated systems as a “natural” extension of the existing smart urban ecosystem. This vision is unfolding through autonomous delivery robots (the Singapore Post’s delivery drone trials in partnership with AirBus helicopters) and driverless bus shuttles from Easymile, EZ10.

Meanwhile, Singapore hotels are employing state-subsidized service robots to clean rooms and deliver linen and supplies, and robots for early childhood education have been piloted to understand how robots can be used in pre-schools in the future. Health and social care is one of the fastest growing industries for robots and automation in Singapore and globally.

Dubai
Dubai is another emerging prototype of a state-controlled smart city. But rather than seeing robotization simply as a way to improve the running of systems, Dubai is intensively robotizing public services with the aim of creating the “happiest city on Earth.” Urban robot experimentation in Dubai reveals that authoritarian state regimes are finding innovative ways to use robots in public services, transportation, policing, and surveillance.

National governments are in competition to position themselves on the global politico-economic landscape through robotics, and they are also striving to position themselves as regional leaders. This was the thinking behind the city’s September 2017 test flight of a flying taxi developed by the German drone firm Volocopter—staged to “lead the Arab world in innovation.” Dubai’s objective is to automate 25% of its transport system by 2030.

It is currently also experimenting with Barcelona-based PAL Robotics’ humanoid police officer and Singapore-based vehicle OUTSAW. If the experiments are successful, the government has announced it will robotize 25% of the police force by 2030.

While imaginary robots are fueling our imagination more than ever—from Ghost in the Shell to Blade Runner 2049—real-world robots make us rethink our urban lives.

These three urban robotic living labs—Tokyo, Singapore, Dubai—help us gauge what kind of future is being created, and by whom. From hyper-robotized Tokyo to smartest Singapore and happy, crime-free Dubai, these three comparisons show that, no matter what the context, robots are perceived as a means to achieve global futures based on a specific national imagination. Just like the films, they demonstrate the role of the state in envisioning and creating that future.

This article was originally published on The Conversation. Read the original article.

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Posted in Human Robots

#432433 Just a Few of the Amazing Things AI Is ...

In an interview at Singularity University’s Exponential Medicine in San Diego, Neil Jacobstein shared some groundbreaking developments in artificial intelligence for healthcare.

Jacobstein is Singularity University’s faculty chair in AI and robotics, a distinguished visiting scholar at Stanford University’s MediaX Program, and has served as an AI technical consultant on research and development projects for organizations like DARPA, Deloitte, NASA, Boeing, and many more.

According to Jacobstein, 2017 was an exciting year for AI, not only due to how the technology matured, but also thanks to new applications and successes in several health domains.

Among the examples cited in his interview, Jacobstein referenced a 2017 breakthrough at Stanford University where an AI system was used for skin cancer identification. To train the system, the team showed a convolutional neural network images of 129,000 skin lesions. The system was able to differentiate between images displaying malignant melanomas and benign skin lesions. When tested against 21 board–certified dermatologists, the system made comparable diagnostic calls.

Pattern recognition and image detection are just two examples of successful uses of AI in healthcare and medicine—the list goes on.

“We’re seeing AI and machine learning systems performing at narrow tasks remarkably well, and getting breakthrough results both in AI for problem-solving and AI with medicine,” Jacobstein said.

He continued, “We are not seeing super-human terminator systems. But we are seeing more members of the AI community paying attention to managing the downside risk of AI responsibly.”

Watch the full interview to learn more examples of how AI is advancing in healthcare and medicine and elsewhere and what Jacobstein thinks is coming next.

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