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#435167 A Closer Look at the Robots Helping Us ...

Buck Rogers had Twiki. Luke Skywalker palled around with C-3PO and R2-D2. And astronauts aboard the International Space Station (ISS) now have their own robotic companions in space—Astrobee.

A pair of the cube-shaped robots were launched to the ISS during an April re-supply mission and are currently being commissioned for use on the space station. The free-flying space robots, dubbed Bumble and Honey, are the latest generation of robotic machines to join the human crew on the ISS.

Exploration of the solar system and beyond will require autonomous machines that can assist humans with numerous tasks—or go where we cannot. NASA has said repeatedly that robots will be instrumental in future space missions to the moon, Mars, and even to the icy moon Europa.

The Astrobee robots will specifically test robotic capabilities in zero gravity, replacing the SPHERES (Synchronized Position Hold, Engage, Reorient, Experimental Satellite) robots that have been on the ISS for more than a decade to test various technologies ranging from communications to navigation.

The 18-sided robots, each about the size of a volleyball or an oversized Dungeons and Dragons die, use CO2-based cold-gas thrusters for movement and a series of ultrasonic beacons for orientation. The Astrobee robots, on the other hand, can propel themselves autonomously around the interior of the ISS using electric fans and six cameras.

The modular design of the Astrobee robots means they are highly plug-and-play, capable of being reconfigured with different hardware modules. The robots’ software is also open-source, encouraging scientists and programmers to develop and test new algorithms and features.

And, yes, the Astrobee robots will be busy as bees once they are fully commissioned this fall, with experiments planned to begin next year. Scientists hope to learn more about how robots can assist space crews and perform caretaking duties on spacecraft.

Robots Working Together
The Astrobee robots are expected to be joined by a familiar “face” on the ISS later this year—the humanoid robot Robonaut.

Robonaut, also known as R2, was the first US-built robot on the ISS. It joined the crew back in 2011 without legs, which were added in 2014. However, the installation never entirely worked, as R2 experienced power failures that eventually led to its return to Earth last year to fix the problem. If all goes as planned, the space station’s first humanoid robot will return to the ISS to lend a hand to the astronauts and the new robotic arrivals.

In particular, NASA is interested in how the two different robotic platforms can complement each other, with an eye toward outfitting the agency’s proposed lunar orbital space station with various robots that can supplement a human crew.

“We don’t have definite plans for what would happen on the Gateway yet, but there’s a general recognition that intra-vehicular robots are important for space stations,” Astrobee technical lead Trey Smith in the NASA Intelligent Robotics Group told IEEE Spectrum. “And so, it would not be surprising to see a mobile manipulator like Robonaut, and a free flyer like Astrobee, on the Gateway.”

While the focus on R2 has been to test its capabilities in zero gravity and to use it for mundane or dangerous tasks in space, the technology enabling the humanoid robot has proven to be equally useful on Earth.

For example, R2 has amazing dexterity for a robot, with sensors, actuators, and tendons comparable to the nerves, muscles, and tendons in a human hand. Based on that design, engineers are working on a robotic glove that can help factory workers, for instance, do their jobs better while reducing the risk of repetitive injuries. R2 has also inspired development of a robotic exoskeleton for both astronauts in space and paraplegics on Earth.

Working Hard on Soft Robotics
While innovative and technologically sophisticated, Astrobee and Robonaut are typical robots in that neither one would do well in a limbo contest. In other words, most robots are limited in their flexibility and agility based on current hardware and materials.

A subfield of robotics known as soft robotics involves developing robots with highly pliant materials that mimic biological organisms in how they move. Scientists at NASA’s Langley Research Center are investigating how soft robots could help with future space exploration.

Specifically, the researchers are looking at a series of properties to understand how actuators—components responsible for moving a robotic part, such as Robonaut’s hand—can be built and used in space.

The team first 3D prints a mold and then pours a flexible material like silicone into the mold. Air bladders or chambers in the actuator expand and compress using just air.

Some of the first applications of soft robotics sound more tool-like than R2-D2-like. For example, two soft robots could connect to produce a temporary shelter for astronauts on the moon or serve as an impromptu wind shield during one of Mars’ infamous dust storms.

The idea is to use soft robots in situations that are “dangerous, dirty, or dull,” according to Jack Fitzpatrick, a NASA intern working on the soft robotics project at Langley.

Working on Mars
Of course, space robots aren’t only designed to assist humans. In many instances, they are the only option to explore even relatively close celestial bodies like Mars. Four American-made robotic rovers have been used to investigate the fourth planet from the sun since 1997.

Opportunity is perhaps the most famous, covering about 25 miles of terrain across Mars over 15 years. A dust storm knocked it out of commission last year, with NASA officially ending the mission in February.

However, the biggest and baddest of the Mars rovers, Curiosity, is still crawling across the Martian surface, sending back valuable data since 2012. The car-size robot carries 17 cameras, a laser to vaporize rocks for study, and a drill to collect samples. It is on the hunt for signs of biological life.

The next year or two could see a virtual traffic jam of robots to Mars. NASA’s Mars 2020 Rover is next in line to visit the Red Planet, sporting scientific gadgets like an X-ray fluorescence spectrometer for chemical analyses and ground-penetrating radar to see below the Martian surface.

This diagram shows the instrument payload for the Mars 2020 mission. Image Credit: NASA.
Meanwhile, the Europeans have teamed with the Russians on a rover called Rosalind Franklin, named after a famed British chemist, that will drill down into the Martian ground for evidence of past or present life as soon as 2021.

The Chinese are also preparing to begin searching for life on Mars using robots as soon as next year, as part of the country’s Mars Global Remote Sensing Orbiter and Small Rover program. The mission is scheduled to be the first in a series of launches that would culminate with bringing samples back from Mars to Earth.

Perhaps there is no more famous utterance in the universe of science fiction as “to boldly go where no one has gone before.” However, the fact is that human exploration of the solar system and beyond will only be possible with robots of different sizes, shapes, and sophistication.

Image Credit: NASA. Continue reading

Posted in Human Robots

#435159 This Week’s Awesome Stories From ...

ARTIFICIAL INTELLIGENCE
DeepMind Can Now Beat Us at Multiplayer Games Too
Cade Metz | The New York Times
“DeepMind’s project is part of a broad effort to build artificial intelligence that can play enormously complex, three-dimensional video games, including Quake III, Dota 2 and StarCraft II. Many researchers believe that success in the virtual arena will eventually lead to automated systems with improved abilities in the real world.”

ROBOTICS
Tiny Robots Carry Stem Cells Through a Mouse
Emily Waltz | IEEE Spectrum
“Engineers have built microrobots to perform all sorts of tasks in the body, and can now add to that list another key skill: delivering stem cells. In a paper, published [May 29] in Science Robotics, researchers describe propelling a magnetically-controlled, stem-cell-carrying bot through a live mouse.” [Video shows microbots navigating a microfluidic chip. MRI could not be used to image the mouse as the bots navigate magnetically.]

COMPUTING
How a Quantum Computer Could Break 2048-Bit RSA Encryption in 8 Hours
Emerging Technology From the arXiv | MIT Technology Review
“[Two researchers] have found a more efficient way for quantum computers to perform the code-breaking calculations, reducing the resources they require by orders of magnitude. Consequently, these machines are significantly closer to reality than anyone suspected.” [The arXiv is a pre-print server for research that has not yet been peer reviewed.]

AUTOMATION
Lyft Has Completed 55,000 Self Driving Rides in Las Vegas
Christine Fisher | Engadget
“One year ago, Lyft launched its self-driving ride service in Las Vegas. Today, the company announced its 30-vehicle fleet has made 55,000 trips. That makes it the largest commercial program of its kind in the US.”

TRANSPORTATION
Flying Car Startup Alaka’i Bets Hydrogen Can Outdo Batteries
Eric Adams | Wired
“Alaka’i says the final product will be able to fly for up to four hours and cover 400 miles on a single load of fuel, which can be replenished in 10 minutes at a hydrogen fueling station. It has built a functional, full-scale prototype that will make its first flight ‘imminently,’ a spokesperson says.”

ETHICS
The World Economic Forum Wants to Develop Global Rules for AI
Will Knight | MIT Technology Review
“This week, AI experts, politicians, and CEOs will gather to ask an important question: Can the United States, China, or anyone else agree on how artificial intelligence should be used and controlled?”

SPACE
Building a Rocket in a Garage to Take on SpaceX and Blue Origin
Jackson Ryan | CNET
“While billionaire entrepreneurs like SpaceX’s Elon Musk and Blue Origin’s Jeff Bezos push the boundaries of human spaceflight and exploration, a legion of smaller private startups around the world have been developing their own rocket technology to launch lighter payloads into orbit.”

Image Credit: Kevin Crosby / Unsplash Continue reading

Posted in Human Robots

#435152 The Futuristic Tech Disrupting Real ...

In the wake of the housing market collapse of 2008, one entrepreneur decided to dive right into the failing real estate industry. But this time, he didn’t buy any real estate to begin with. Instead, Glenn Sanford decided to launch the first-ever cloud-based real estate brokerage, eXp Realty.

Contracting virtual platform VirBELA to build out the company’s mega-campus in VR, eXp Realty demonstrates the power of a dematerialized workspace, throwing out hefty overhead costs and fundamentally redefining what ‘real estate’ really means. Ten years later, eXp Realty has an army of 14,000 agents across all 50 US states, 3 Canadian provinces, and 400 MLS market areas… all without a single physical office.

But VR is just one of many exponential technologies converging to revolutionize real estate and construction. As floating cities and driverless cars spread out your living options, AI and VR are together cutting out the middleman.

Already, the global construction industry is projected to surpass $12.9 trillion in 2022, and the total value of the US housing market alone grew to $33.3 trillion last year. Both vital for our daily lives, these industries will continue to explode in value, posing countless possibilities for disruption.

In this blog, I’ll be discussing the following trends:

New prime real estate locations;
Disintermediation of the real estate broker and search;
Materials science and 3D printing in construction.

Let’s dive in!

Location Location Location
Until today, location has been the name of the game when it comes to hunting down the best real estate. But constraints on land often drive up costs while limiting options, and urbanization is only exacerbating the problem.

Beyond the world of virtual real estate, two primary mechanisms are driving the creation of new locations.

(1) Floating Cities

Offshore habitation hubs, floating cities have long been conceived as a solution to rising sea levels, skyrocketing urban populations, and threatened ecosystems. In success, they will soon unlock an abundance of prime real estate, whether for scenic living, commerce, education, or recreation.

One pioneering model is that of Oceanix City, designed by Danish architect Bjarke Ingels and a host of other domain experts. Intended to adapt organically over time, Oceanix would consist of a galaxy of mass-produced, hexagonal floating modules, built as satellite “cities” off coastal urban centers and sustained by renewable energies.

While individual 4.5-acre platforms would each sustain 300 people, these hexagonal modules are designed to link into 75-acre tessellations sustaining up to 10,000 residents. Each anchored to the ocean floor using biorock, Oceanix cities are slated to be closed-loop systems, as external resources are continuously supplied by automated drone networks.

Electric boats or flying cars might zoom you to work, city-embedded water capture technologies would provide your water, and while vertical and outdoor farming supply your family meal, share economies would dominate goods provision.

AERIAL: Located in calm, sheltered waters, near coastal megacities, OCEANIX City will be an adaptable, sustainable, scalable, and affordable solution for human life on the ocean. Image Credit: OCEANIX/BIG-Bjarke Ingels Group.
Joined by countless government officials whose islands risk submersion at the hands of sea level rise, the UN is now getting on board. And just this year, seasteading is exiting the realm of science fiction and testing practical waters.

As French Polynesia seeks out robust solutions to sea level rise, their government has now joined forces with the San Francisco-based Seasteading Institute. With a newly designated special economic zone and 100 acres of beachfront, this joint Floating Island Project could even see up to a dozen inhabitable structures by 2020. And what better to fund the $60 million project than the team’s upcoming ICO?

But aside from creating new locations, autonomous vehicles (AVs) and flying cars are turning previously low-demand land into the prime real estate of tomorrow.

(2) Autonomous Electric Vehicles and Flying Cars

Today, the value of a location is a function of its proximity to your workplace, your city’s central business district, the best schools, or your closest friends.

But what happens when driverless cars desensitize you to distance, or Hyperloop and flying cars decimate your commute time? Historically, every time new transit methods have hit the mainstream, tolerance for distance has opened up right alongside them, further catalyzing city spread.

And just as Hyperloop and the Boring Company aim to make your commute immaterial, autonomous vehicle (AV) ridesharing services will spread out cities in two ways: (1) by drastically reducing parking spaces needed (vertical parking decks = more prime real estate); and (2) by untethering you from the steering wheel. Want an extra two hours of sleep on the way to work? Schedule a sleeper AV and nap on your route to the office. Need a car-turned-mobile-office? No problem.

Meanwhile, aerial taxis (i.e. flying cars) will allow you to escape ground congestion entirely, delivering you from bedroom to boardroom at decimated time scales.

Already working with regulators, Uber Elevate has staked ambitious plans for its UberAIR airborne taxi project. By 2023, Uber anticipates rolling out flying drones in its two first pilot cities, Los Angeles and Dallas. Flying between rooftop skyports, drones would carry passengers at a height of 1,000 to 2,000 feet at speeds between 100 to 200 mph. And while costs per ride are anticipated to resemble those of an Uber Black based on mileage, prices are projected to soon drop to those of an UberX.

But the true economic feat boils down to this: if I were to commute 50 to 100 kilometers, I could get two or three times the house for the same price. (Not to mention the extra living space offered up by my now-unneeded garage.)

All of a sudden, virtual reality, broadband, AVs, or high-speed vehicles are going to change where we live and where we work. So rather than living in a crowded, dense urban core for access to jobs and entertainment, our future of personalized, autonomous, low-cost transport opens the luxury of rural areas to all without compromising the benefits of a short commute.

Once these drivers multiply your real estate options, how will you select your next home?

Disintermediation: Say Bye to Your Broker
In a future of continuous and personalized preference-tracking, why hire a human agent who knows less about your needs and desires than a personal AI?

Just as disintermediation is cutting out bankers and insurance agents, so too is it closing in on real estate brokers. Over the next decade, as AI becomes your agent, VR will serve as your medium.

To paint a more vivid picture of how this will look, over 98 percent of your home search will be conducted from the comfort of your couch through next-generation VR headgear.

Once you’ve verbalized your primary desires for home location, finishings, size, etc. to your personal AI, it will offer you top picks, tour-able 24/7, with optional assistance by a virtual guide and constantly updated data. As a seller, this means potential buyers from two miles, or two continents, away.

Throughout each immersive VR tour, advanced eye-tracking software and a permissioned machine learning algorithm follow your gaze, further learn your likes and dislikes, and intelligently recommend other homes or commercial residences to visit.

Curious as to what the living room might look like with a fresh coat of blue paint and a white carpet? No problem! VR programs will be able to modify rendered environments instantly, changing countless variables, from furniture materials to even the sun’s orientation. Keen to input your own furniture into a VR-rendered home? Advanced AIs could one day compile all your existing furniture, electronics, clothing, decorations, and even books, virtually organizing them across any accommodating new space.

As 3D scanning technologies make extraordinary headway, VR renditions will only grow cheaper and higher resolution. One company called Immersive Media (disclosure: I’m an investor and advisor) has a platform for 360-degree video capture and distribution, and is already exploring real estate 360-degree video.

Smaller firms like Studio 216, Vieweet, Arch Virtual, ArX Solutions, and Rubicon Media can similarly capture and render models of various properties for clients and investors to view and explore. In essence, VR real estate platforms will allow you to explore any home for sale, do the remodel, and determine if it truly is the house of your dreams.

Once you’re ready to make a bid, your AI will even help estimate a bid, process and submit your offer. Real estate companies like Zillow, Trulia, Move, Redfin, ZipRealty (acquired by Realogy in 2014) and many others have already invested millions in machine learning applications to make search, valuation, consulting, and property management easier, faster, and much more accurate.

But what happens if the home you desire most means starting from scratch with new construction?

New Methods and Materials for Construction
For thousands of years, we’ve been constrained by the construction materials of nature. We built bricks from naturally abundant clay and shale, used tree limbs as our rooftops and beams, and mastered incredible structures in ancient Rome with the use of cement.

But construction is now on the cusp of a materials science revolution. Today, I’d like to focus on three key materials:

Upcycled Materials

Imagine if you could turn the world’s greatest waste products into their most essential building blocks. Thanks to UCLA researchers at CO2NCRETE, we can already do this with carbon emissions.

Today, concrete produces about five percent of all greenhouse gas (GHG) emissions. But what if concrete could instead conserve greenhouse emissions? CO2NCRETE engineers capture carbon from smokestacks and combine it with lime to create a new type of cement. The lab’s 3D printers then shape the upcycled concrete to build entirely new structures. Once conquered at scale, upcycled concrete will turn a former polluter into a future conserver.

Or what if we wanted to print new residences from local soil at hand? Marking an extraordinary convergence between robotics and 3D printing, the Institute of Advanced Architecture of Catalonia (IAAC) is already working on a solution.

In a major feat for low-cost construction in remote zones, IAAC has found a way to convert almost any soil into a building material with three times the tensile strength of industrial clay. Offering myriad benefits, including natural insulation, low GHG emissions, fire protection, air circulation, and thermal mediation, IAAC’s new 3D printed native soil can build houses on-site for as little as $1,000.

Nanomaterials

Nano- and micro-materials are ushering in a new era of smart, super-strong, and self-charging buildings. While carbon nanotubes dramatically increase the strength-to-weight ratio of skyscrapers, revolutionizing their structural flexibility, nanomaterials don’t stop here.

Several research teams are pioneering silicon nanoparticles to capture everyday light flowing through our windows. Little solar cells at the edges of windows then harvest this energy for ready use. Researchers at the US National Renewable Energy Lab have developed similar smart windows. Turning into solar panels when bathed in sunlight, these thermochromic windows will power our buildings, changing color as they do.

Self-Healing Infrastructure

The American Society of Civil Engineers estimates that the US needs to spend roughly $4.5 trillion to fix nationwide roads, bridges, dams, and common infrastructure by 2025. But what if infrastructure could fix itself?

Enter self-healing concrete. Engineers at Delft University have developed bio-concrete that can repair its own cracks. As head researcher Henk Jonkers explains, “What makes this limestone-producing bacteria so special is that they are able to survive in concrete for more than 200 years and come into play when the concrete is damaged. […] If cracks appear as a result of pressure on the concrete, the concrete will heal these cracks itself.”

But bio-concrete is only the beginning of self-healing technologies. As futurist architecture firms start printing plastic and carbon-fiber houses like the stunner seen below (using Branch Technologies’ 3D printing technology), engineers have begun tackling self-healing plastic.

And in a bid to go smart, burgeoning construction projects have started embedding sensors for preemptive detection. Beyond materials and sensors, however, construction methods are fast colliding into robotics and 3D printing.

While some startups and research institutes have leveraged robot swarm construction (namely, Harvard’s robotic termite-like swarm of programmed constructors), others have taken to large-scale autonomous robots.

One such example involves Fastbrick Robotics. After multiple iterations, the company’s Hadrian X end-to-end bricklaying robot can now autonomously build a fully livable, 180-square meter home in under 3 days. Using a laser-guided robotic attachment, the all-in-one brick-loaded truck simply drives to a construction site and directs blocks through its robotic arm in accordance with a 3D model.

Layhead. Image Credit: Fastbrick Robotics.
Meeting verified building standards, Hadrian and similar solutions hold massive promise in the long term, deployable across post-conflict refugee sites and regions recovering from natural catastrophes.

Imagine the implications. Eliminating human safety concerns and unlocking any environment, autonomous builder robots could collaboratively build massive structures in space or deep underwater habitats.

Final Thoughts
Where, how, and what we live in form a vital pillar of our everyday lives. The concept of “home” is unlikely to disappear anytime soon. At the same time, real estate and construction are two of the biggest playgrounds for technological convergence, each on the verge of revolutionary disruption.

As underlying shifts in transportation, land reclamation, and the definition of “space” (real vs. virtual) take hold, the real estate market is about to explode in value, spreading out urban centers on unprecedented scales and unlocking vast new prime “property.”

Meanwhile, converging advancements in AI and VR are fundamentally disrupting the way we design, build, and explore new residences. Just as mirror worlds create immersive, virtual real estate economies, VR tours and AI agents are absorbing both sides of the coin to entirely obliterate the middleman.

And as materials science breakthroughs meet new modes of construction, the only limits to tomorrow’s structures are those of our own imagination.

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Image Credit: OCEANIX/BIG-Bjarke Ingels Group. Continue reading

Posted in Human Robots

#435145 How Big Companies Can Simultaneously Run ...

We live in the age of entrepreneurs. New startups seem to appear out of nowhere and challenge not only established companies, but entire industries. Where startup unicorns were once mythical creatures, they now seem abundant, not only increasing in numbers but also in the speed with which they can gain the minimum one-billion-dollar valuations to achieve this status.

But no matter how well things go for innovative startups, how many new success stories we hear, and how much space they take up in the media, the story that they are the best or only source of innovation isn’t entirely accurate.

Established organizations, or legacy organizations, can be incredibly innovative too. And while innovation is much more difficult in established organizations than in startups because they have much more complex systems—nobody is more likely to succeed in their innovation efforts than established organizations.

Unlike startups, established organizations have all the resources. They have money, customers, data, suppliers, partners, and infrastructure, which put them in a far better position to transform new ideas into concrete, value-creating, successful offerings than startups.

However, for established organizations, becoming an innovation champion in these times of rapid change requires new rules of engagement.

Many organizations commit the mistake of engaging in innovation as if it were a homogeneous thing that should be approached in the same way every time, regardless of its purpose. In my book, Transforming Legacy Organizations, I argue that innovation in established organizations must actually be divided into three different tracks: optimizing, augmenting, and mutating innovation.

All three are important, and to complicate matters further, organizations must execute all three types of innovation at the same time.

Optimizing Innovation
The first track is optimizing innovation. This type of innovation is the majority of what legacy organizations already do today. It is, metaphorically speaking, the extra blade on the razor. A razor manufacturer might launch a new razor that has not just three, but four blades, to ensure an even better, closer, and more comfortable shave. Then one or two years later, they say they are now launching a razor that has not only four, but five blades for an even better, closer, and more comfortable shave. That is optimizing innovation.

Adding extra blades on the razor is where the established player reigns.

No startup with so much as a modicum of sense would even try to beat the established company in this type of innovation. And this continuous optimization, both on the operational and customer facing sides, is important. In the short term. It pays the rent. But it’s far from enough. There are limits to how many blades a razor needs, and optimizing innovation only improves upon the past.

Augmenting Innovation
Established players must also go beyond optimization and prepare for the future through augmenting innovation.

The digital transformation projects that many organizations are initiating can be characterized as augmenting innovation. In the first instance, it is about upgrading core offerings and processes from analog to digital. Or, if you’re born digital, you’ve probably had to augment the core to become mobile-first. Perhaps you have even entered the next augmentation phase, which involves implementing artificial intelligence. Becoming AI-first, like the Amazons, Microsofts, Baidus, and Googles of the world, requires great technological advancements. And it’s difficult. But technology may, in fact, be a minor part of the task.

The biggest challenge for augmenting innovation is probably culture.

Only legacy organizations that manage to transform their cultures from status quo cultures—cultures with a preference for things as they are—into cultures full of incremental innovators can thrive in constant change.

To create a strong innovation culture, an organization needs to thoroughly understand its immune systems. These are the mechanisms that protect the organization and operate around the clock to keep it healthy and stable, just as the body’s immune system operates to keep the body healthy and stable. But in a rapidly changing world, many of these defense mechanisms are no longer appropriate and risk weakening organizations’ innovation power.

When talking about organizational immune systems, there is a clear tendency to simply point to the individual immune system, people’s unwillingness to change.

But this is too simplistic.

Of course, there is human resistance to change, but the organizational immune system, consisting of a company’s key performance indicators (KPIs), rewards systems, legacy IT infrastructure and processes, and investor and shareholder demands, is far more important. So is the organization’s societal immune system, such as legislative barriers, legacy customers and providers, and economic climate.

Luckily, there are many culture hacks that organizations can apply to strengthen their innovation cultures by upgrading their physical and digital workspaces, transforming their top-down work processes into decentralized, agile ones, and empowering their employees.

Mutating Innovation
Upgrading your core and preparing for the future by augmenting innovation is crucial if you want success in the medium term. But to win in the long run and be as or more successful 20 to 30 years from now, you need to invent the future, and challenge your core, through mutating innovation.

This requires involving radical innovators who have a bold focus on experimenting with that which is not currently understood and for which a business case cannot be prepared.

Here you must also physically move away from the core organization when you initiate and run such initiatives. This is sometimes called “innovation on the edges” because the initiatives will not have a chance at succeeding within the core. It will be too noisy as they challenge what currently exists—precisely what the majority of the organization’s employees are working to optimize or augment.

Forward-looking organizations experiment to mutate their core through “X divisions,” sometimes called skunk works or innovation labs.

Lowe’s Innovation Labs, for instance, worked with startups to build in-store robot assistants and zero-gravity 3D printers to explore the future. Mutating innovation might include pursuing partnerships across all imaginable domains or establishing brand new companies, rather than traditional business units, as we see automakers such as Toyota now doing to build software for autonomous vehicles. Companies might also engage in radical open innovation by sponsoring others’ ingenuity. Japan’s top airline ANA is exploring a future of travel that does not involve flying people from point A to point B via the ANA Avatar XPRIZE competition.

Increasing technological opportunities challenge the core of any organization but also create unprecedented potential. No matter what product, service, or experience you create, you can’t rest on your laurels. You have to bring yourself to a position where you have a clear strategy for optimizing, augmenting, and mutating your core and thus transforming your organization.

It’s not an easy job. But, hey, if it were easy, everyone would be doing it. Those who make it, on the other hand, will be the innovation champions of the future.

Image Credit: rock-the-stock / Shutterstock.com

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Posted in Human Robots

#434534 To Extend Our Longevity, First We Must ...

Healthcare today is reactive, retrospective, bureaucratic, and expensive. It’s sick care, not healthcare.

But that is radically changing at an exponential rate.

Through this multi-part blog series on longevity, I’ll take a deep dive into aging, longevity, and healthcare technologies that are working together to dramatically extend the human lifespan, disrupting the $3 trillion healthcare system in the process.

I’ll begin the series by explaining the nine hallmarks of aging, as explained in this journal article. Next, I’ll break down the emerging technologies and initiatives working to combat these nine hallmarks. Finally, I’ll explore the transformative implications of dramatically extending the human health span.

In this blog I’ll cover:

Why the healthcare system is broken
Why, despite this, we live in the healthiest time in human history
The nine mechanisms of aging

Let’s dive in.

The System is Broken—Here’s the Data:

Doctors spend $210 billion per year on procedures that aren’t based on patient need, but fear of liability.
Americans spend, on average, $8,915 per person on healthcare—more than any other country on Earth.
Prescription drugs cost around 50 percent more in the US than in other industrialized countries.
At current rates, by 2025, nearly 25 percent of the US GDP will be spent on healthcare.
It takes 12 years and $359 million, on average, to take a new drug from the lab to a patient.
Only 5 in 5,000 of these new drugs proceed to human testing. From there, only 1 of those 5 is actually approved for human use.

And Yet, We Live in the Healthiest Time in Human History
Consider these insights, which I adapted from Max Roser’s excellent database Our World in Data:

Right now, the countries with the lowest life expectancy in the world still have higher life expectancies than the countries with the highest life expectancy did in 1800.
In 1841, a 5-year-old had a life expectancy of 55 years. Today, a 5-year-old can expect to live 82 years—an increase of 27 years.
We’re seeing a dramatic increase in healthspan. In 1845, a newborn would expect to live to 40 years old. For a 70-year-old, that number became 79. Now, people of all ages can expect to live to be 81 to 86 years old.
100 years ago, 1 of 3 children would die before the age of 5. As of 2015, the child mortality rate fell to just 4.3 percent.
The cancer mortality rate has declined 27 percent over the past 25 years.

Figure: Around the globe, life expectancy has doubled since the 1800s. | Image from Life Expectancy by Max Roser – Our World in Data / CC BY SA
Figure: A dramatic reduction in child mortality in 1800 vs. in 2015. | Image from Child Mortality by Max Roser – Our World in Data / CC BY SA
The 9 Mechanisms of Aging
*This section was adapted from CB INSIGHTS: The Future Of Aging.

Longevity, healthcare, and aging are intimately linked.

With better healthcare, we can better treat some of the leading causes of death, impacting how long we live.

By investigating how to treat diseases, we’ll inevitably better understand what causes these diseases in the first place, which directly correlates to why we age.

Following are the nine hallmarks of aging. I’ll share examples of health and longevity technologies addressing each of these later in this blog series.

Genomic instability: As we age, the environment and normal cellular processes cause damage to our genes. Activities like flying at high altitude, for example, expose us to increased radiation or free radicals. This damage compounds over the course of life and is known to accelerate aging.
Telomere attrition: Each strand of DNA in the body (known as chromosomes) is capped by telomeres. These short snippets of DNA repeated thousands of times are designed to protect the bulk of the chromosome. Telomeres shorten as our DNA replicates; if a telomere reaches a certain critical shortness, a cell will stop dividing, resulting in increased incidence of disease.
Epigenetic alterations: Over time, environmental factors will change how genes are expressed, i.e., how certain sequences of DNA are read and the instruction set implemented.
Loss of proteostasis: Over time, different proteins in our body will no longer fold and function as they are supposed to, resulting in diseases ranging from cancer to neurological disorders.
Deregulated nutrient-sensing: Nutrient levels in the body can influence various metabolic pathways. Among the affected parts of these pathways are proteins like IGF-1, mTOR, sirtuins, and AMPK. Changing levels of these proteins’ pathways has implications on longevity.
Mitochondrial dysfunction: Mitochondria (our cellular power plants) begin to decline in performance as we age. Decreased performance results in excess fatigue and other symptoms of chronic illnesses associated with aging.
Cellular senescence: As cells age, they stop dividing and cannot be removed from the body. They build up and typically cause increased inflammation.
Stem cell exhaustion: As we age, our supply of stem cells begins to diminish as much as 100 to 10,000-fold in different tissues and organs. In addition, stem cells undergo genetic mutations, which reduce their quality and effectiveness at renovating and repairing the body.
Altered intercellular communication: The communication mechanisms that cells use are disrupted as cells age, resulting in decreased ability to transmit information between cells.

Conclusion
Over the past 200 years, we have seen an abundance of healthcare technologies enable a massive lifespan boom.

Now, exponential technologies like artificial intelligence, 3D printing and sensors, as well as tremendous advancements in genomics, stem cell research, chemistry, and many other fields, are beginning to tackle the fundamental issues of why we age.

In the next blog in this series, we will dive into how genome sequencing and editing, along with new classes of drugs, are augmenting our biology to further extend our healthy lives.

What will you be able to achieve with an extra 30 to 50 healthy years (or longer) in your lifespan? Personally, I’m excited for a near-infinite lifespan to take on moonshots.

Join Me
Abundance-Digital Online Community: I’ve created a Digital/Online community of bold, abundance-minded entrepreneurs called Abundance-Digital. Abundance-Digital is my ‘onramp’ for exponential entrepreneurs – those who want to get involved and play at a higher level. Click here to learn more.

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