Tag Archives: discovery

#435822 The Internet Is Coming to the Rest of ...

Posted on September 26, 2019 by Android

People surf it. Spiders crawl it. Gophers navigate it.

Now, a leading group of cognitive biologists and computer scientists want to make the tools of the Internet accessible to the rest of the animal kingdom.

Dubbed the Interspecies Internet, the project aims to provide intelligent animals such as elephants, dolphins, magpies, and great apes with a means to communicate among each other and with people online.

And through artificial intelligence, virtual reality, and other digital technologies, researchers hope to crack the code of all the chirps, yips, growls, and whistles that underpin animal communication.

Oh, and musician Peter Gabriel is involved.

“We can use data analysis and technology tools to give non-humans a lot more choice and control,” the former Genesis frontman, dressed in his signature Nehru-style collar shirt and loose, open waistcoat, told IEEE Spectrum at the inaugural Interspecies Internet Workshop, held Monday in Cambridge, Mass. “This will be integral to changing our relationship with the natural world.”

The workshop was a long time in the making.

Eighteen years ago, Gabriel visited a primate research center in Atlanta, Georgia, where he jammed with two bonobos, a male named Kanzi and his half-sister Panbanisha. It was the first time either bonobo had sat at a piano before, and both displayed an exquisite sense of musical timing and melody.

Gabriel seemed to be speaking to the great apes through his synthesizer. It was a shock to the man who once sang “Shock the Monkey.”

“It blew me away,” he says.

Add in the bonobos’ ability to communicate by pointing to abstract symbols, Gabriel notes, and “you’d have to be deaf, dumb, and very blind not to notice language being used.”

Gabriel eventually teamed up with Internet protocol co-inventor Vint Cerf, cognitive psychologist Diana Reiss, and IoT pioneer Neil Gershenfeld to propose building an Interspecies Internet. Presented in a 2013 TED Talk as an “idea in progress,” the concept proved to be ahead of the technology.

“It wasn’t ready,” says Gershenfeld, director of MIT’s Center for Bits and Atoms. “It needed to incubate.”

So, for the past six years, the architects of the Dolittlesque initiative embarked on two small pilot projects, one for dolphins and one for chimpanzees.

At her Hunter College lab in New York City, Reiss developed what she calls the D-Pad—a touchpad for dolphins.

Reiss had been trying for years to create an underwater touchscreen with which to probe the cognition and communication skills of bottlenose dolphins. But “it was a nightmare coming up with something that was dolphin-safe and would work,” she says.

Her first attempt emitted too much heat. A Wii-like system of gesture recognition proved too difficult to install in the dolphin tanks.

Eventually, she joined forces with Rockefeller University biophysicist Marcelo Magnasco and invented an optical detection system in which images and infrared sensors are projected through an underwater viewing window onto a glass panel, allowing the dolphins to play specially designed apps, including one dubbed Whack-a-Fish.

Meanwhile, in the United Kingdom, Gabriel worked with Alison Cronin, director of the ape rescue center Monkey World, to test the feasibility of using FaceTime with chimpanzees.

The chimps engaged with the technology, Cronin reported at this week’s workshop. However, our hominid cousins proved as adept at videotelephonic discourse as my three-year-old son is at video chatting with his grandparents—which is to say, there was a lot of pass-the-banana-through-the-screen and other silly games, and not much meaningful conversation.

“We can use data analysis and technology tools to give non-humans a lot more choice and control.”
—Peter Gabriel

The buggy, rudimentary attempt at interspecies online communication—what Cronin calls her “Max Headroom experiment”—shows that building the Interspecies Internet will not be as simple as giving out Skype-enabled tablets to smart animals.

“There are all sorts of problems with creating a human-centered experience for another animal,” says Gabriel Miller, director of research and development at the San Diego Zoo.

Miller has been working on animal-focused sensory tools such as an “Elephone” (for elephants) and a “Joybranch” (for birds), but it’s not easy to design efficient interactive systems for other creatures—and for the Interspecies Internet to be successful, Miller points out, “that will be super-foundational.”

Researchers are making progress on natural language processing of animal tongues. Through a non-profit organization called the Earth Species Project, former Firefox designer Aza Raskin and early Twitter engineer Britt Selvitelle are applying deep learning algorithms developed for unsupervised machine translation of human languages to fashion a Rosetta Stone–like tool capable of interpreting the vocalizations of whales, primates, and other animals.

Inspired by the scientists who first documented the complex sonic arrangements of humpback whales in the 1960s—a discovery that ushered in the modern marine conservation movement—Selvitelle hopes that an AI-powered animal translator can have a similar effect on environmentalism today.

“A lot of shifts happen when someone who doesn’t have a voice gains a voice,” he says.

A challenge with this sort of AI software remains verification and validation. Normally, machine-learning algorithms are benchmarked against a human expert, but who is to say if a cybernetic translation of a sperm whale’s clicks is accurate or not?

One could back-translate an English expression into sperm whale-ese and then into English again. But with the great apes, there might be a better option.

According to primatologist Sue Savage-Rumbaugh, expertly trained bonobos could serve as bilingual interpreters, translating the argot of apes into the parlance of people, and vice versa.

Not just any trained ape will do, though. They have to grow up in a mixed Pan/Homo environment, as Kanzi and Panbanisha were.

“If I can have a chat with a cow, maybe I can have more compassion for it.”
—Jeremy Coller

Those bonobos were raised effectively from birth both by Savage-Rumbaugh, who taught the animals to understand spoken English and to communicate via hundreds of different pictographic “lexigrams,” and a bonobo mother named Matata that had lived for six years in the Congolese rainforests before her capture.

Unlike all other research primates—which are brought into captivity as infants, reared by human caretakers, and have limited exposure to their natural cultures or languages—those apes thus grew up fluent in both bonobo and human.

Panbanisha died in 2012, but Kanzi, aged 38, is still going strong, living at an ape sanctuary in Des Moines, Iowa. Researchers continue to study his cognitive abilities—Francine Dolins, a primatologist at the University of Michigan-Dearborn, is running one study in which Kanzi and other apes hunt rabbits and forage for fruit through avatars on a touchscreen. Kanzi could, in theory, be recruited to check the accuracy of any Google Translate–like app for bonobo hoots, barks, grunts, and cries.

Alternatively, Kanzi could simply provide Internet-based interpreting services for our two species. He’s already proficient at video chatting with humans, notes Emily Walco, a PhD student at Harvard University who has personally Skyped with Kanzi. “He was super into it,” Walco says.

And if wild bonobos in Central Africa can be coaxed to gather around a computer screen, Savage-Rumbaugh is confident Kanzi could communicate with them that way. “It can all be put together,” she says. “We can have an Interspecies Internet.”

“Both the technology and the knowledge had to advance,” Savage-Rumbaugh notes. However, now, “the techniques that we learned could really be extended to a cow or a pig.”

That’s music to the ears of Jeremy Coller, a private equity specialist whose foundation partially funded the Interspecies Internet Workshop. Coller is passionate about animal welfare and has devoted much of his philanthropic efforts toward the goal of ending factory farming.

At the workshop, his foundation announced the creation of the Coller Doolittle Prize, a US $100,000 award to help fund further research related to the Interspecies Internet. (A working group also formed to synthesize plans for the emerging field, to facilitate future event planning, and to guide testing of shared technology platforms.)

Why would a multi-millionaire with no background in digital communication systems or cognitive psychology research want to back the initiative? For Coller, the motivation boils to interspecies empathy.

“If I can have a chat with a cow,” he says, “maybe I can have more compassion for it.”

An abridged version of this post appears in the September 2019 print issue as “Elephants, Dolphins, and Chimps Need the Internet, Too.” Continue reading →

Posted in Human Robots

#435575 How an AI Startup Designed a Drug ...

Posted on September 9, 2019 by Android

Discovering a new drug can take decades, billions of dollars, and untold man hours from some of the smartest people on the planet. Now a startup says it’s taken a significant step towards speeding the process up using AI.

The typical drug discovery process involves carrying out physical tests on enormous libraries of molecules, and even with the help of robotics it’s an arduous process. The idea of sidestepping this by using computers to virtually screen for promising candidates has been around for decades. But progress has been underwhelming, and it’s still not a major part of commercial pipelines.

Recent advances in deep learning, however, have reignited hopes for the field, and major pharma companies have started tying up with AI-powered drug discovery startups. And now Insilico Medicine has used AI to design a molecule that effectively targets a protein involved in fibrosis—the formation of excess fibrous tissue—in mice in just 46 days.

The platform the company has developed combines two of the hottest sub-fields of AI: the generative adversarial networks, or GANs, which power deepfakes, and reinforcement learning, which is at the heart of the most impressive game-playing AI advances of recent years.

In a paper in Nature Biotechnology, the company’s researchers describe how they trained their model on all the molecules already known to target this protein as well as many other active molecules from various datasets. The model was then used to generate 30,000 candidate molecules.

Unlike most previous efforts, they went a step further and selected the most promising molecules for testing in the lab. The 30,000 candidates were whittled down to just 6 using more conventional drug discovery approaches and were then synthesized in the lab. They were put through increasingly stringent tests, but the leading candidate was found to be effective at targeting the desired protein and behaved as one would hope a drug would.

The authors are clear that the results are just a proof-of-concept, which company CEO Alex Zhavoronkov told Wired stemmed from a challenge set by a pharma partner to design a drug as quickly as possible. But they say they were able to carry out the process faster than traditional methods for a fraction of the cost.

There are some caveats. For a start, the protein being targeted is already very well known and multiple effective drugs exist for it. That gave the company a wealth of data to train their model on, something that isn’t the case for many of the diseases where we urgently need new drugs.

The company’s platform also only targets the very initial stages of the drug discovery process. The authors concede in their paper that the molecules would still take considerable optimization in the lab before they’d be true contenders for clinical trials.

“And that is where you will start to begin to commence to spend the vast piles of money that you will eventually go through in trying to get a drug to market,” writes Derek Lowe in his blog In The Pipeline. The part of the discovery process that the platform tackles represents a tiny fraction of the total cost of drug development, he says.

Nonetheless, the research is a definite advance for virtual screening technology and an important marker of the potential of AI for designing new medicines. Zhavoronkov also told Wired that this research was done more than a year ago, and they’ve since adapted the platform to go after harder drug targets with less data.

And with big pharma companies desperate to slash their ballooning development costs and find treatments for a host of intractable diseases, they can use all the help they can get.

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Posted in Human Robots

#435056 How Researchers Used AI to Better ...

Posted on May 9, 2019 by Android

A few years back, DeepMind’s Demis Hassabis famously prophesized that AI and neuroscience will positively feed into each other in a “virtuous circle.” If realized, this would fundamentally expand our insight into intelligence, both machine and human.

We’ve already seen some proofs of concept, at least in the brain-to-AI direction. For example, memory replay, a biological mechanism that fortifies our memories during sleep, also boosted AI learning when abstractly appropriated into deep learning models. Reinforcement learning, loosely based on our motivation circuits, is now behind some of AI’s most powerful tools.

Hassabis is about to be proven right again.

Last week, two studies independently tapped into the power of ANNs to solve a 70-year-old neuroscience mystery: how does our visual system perceive reality?

The first, published in Cell, used generative networks to evolve DeepDream-like images that hyper-activate complex visual neurons in monkeys. These machine artworks are pure nightmare fuel to the human eye; but together, they revealed a fundamental “visual hieroglyph” that may form a basic rule for how we piece together visual stimuli to process sight into perception.

In the second study, a team used a deep ANN model—one thought to mimic biological vision—to synthesize new patterns tailored to control certain networks of visual neurons in the monkey brain. When directly shown to monkeys, the team found that the machine-generated artworks could reliably activate predicted populations of neurons. Future improved ANN models could allow even better control, giving neuroscientists a powerful noninvasive tool to study the brain. The work was published in Science.

The individual results, though fascinating, aren’t necessarily the point. Rather, they illustrate how scientists are now striving to complete the virtuous circle: tapping AI to probe natural intelligence. Vision is only the beginning—the tools can potentially be expanded into other sensory domains. And the more we understand about natural brains, the better we can engineer artificial ones.

It’s a “great example of leveraging artificial intelligence to study organic intelligence,” commented Dr. Roman Sandler at Kernel.co on Twitter.

Why Vision?
ANNs and biological vision have quite the history.

In the late 1950s, the legendary neuroscientist duo David Hubel and Torsten Wiesel became some of the first to use mathematical equations to understand how neurons in the brain work together.

In a series of experiments—many using cats—the team carefully dissected the structure and function of the visual cortex. Using myriads of images, they revealed that vision is processed in a hierarchy: neurons in “earlier” brain regions, those closer to the eyes, tend to activate when they “see” simple patterns such as lines. As we move deeper into the brain, from the early V1 to a nub located slightly behind our ears, the IT cortex, neurons increasingly respond to more complex or abstract patterns, including faces, animals, and objects. The discovery led some scientists to call certain IT neurons “Jennifer Aniston cells,” which fire in response to pictures of the actress regardless of lighting, angle, or haircut. That is, IT neurons somehow extract visual information into the “gist” of things.

That’s not trivial. The complex neural connections that lead to increasing abstraction of what we see into what we think we see—what we perceive—is a central question in machine vision: how can we teach machines to transform numbers encoding stimuli into dots, lines, and angles that eventually form “perceptions” and “gists”? The answer could transform self-driving cars, facial recognition, and other computer vision applications as they learn to better generalize.

Hubel and Wiesel’s Nobel-prize-winning studies heavily influenced the birth of ANNs and deep learning. Much of earlier ANN “feed-forward” model structures are based on our visual system; even today, the idea of increasing layers of abstraction—for perception or reasoning—guide computer scientists to build AI that can better generalize. The early romance between vision and deep learning is perhaps the bond that kicked off our current AI revolution.

It only seems fair that AI would feed back into vision neuroscience.

Hieroglyphs and Controllers
In the Cell study, a team led by Dr. Margaret Livingstone at Harvard Medical School tapped into generative networks to unravel IT neurons’ complex visual alphabet.

Scientists have long known that neurons in earlier visual regions (V1) tend to fire in response to “grating patches” oriented in certain ways. Using a limited set of these patches like letters, V1 neurons can “express a visual sentence” and represent any image, said Dr. Arash Afraz at the National Institute of Health, who was not involved in the study.

But how IT neurons operate remained a mystery. Here, the team used a combination of genetic algorithms and deep generative networks to “evolve” computer art for every studied neuron. In seven monkeys, the team implanted electrodes into various parts of the visual IT region so that they could monitor the activity of a single neuron.

The team showed each monkey an initial set of 40 images. They then picked the top 10 images that stimulated the highest neural activity, and married them to 30 new images to “evolve” the next generation of images. After 250 generations, the technique, XDREAM, generated a slew of images that mashed up contorted face-like shapes with lines, gratings, and abstract shapes.

This image shows the evolution of an optimum image for stimulating a visual neuron in a monkey. Image Credit: Ponce, Xiao, and Schade et al. – Cell.
“The evolved images look quite counter-intuitive,” explained Afraz. Some clearly show detailed structures that resemble natural images, while others show complex structures that can’t be characterized by our puny human brains.

This figure shows natural images (right) and images evolved by neurons in the inferotemporal cortex of a monkey (left). Image Credit: Ponce, Xiao, and Schade et al. – Cell.
“What started to emerge during each experiment were pictures that were reminiscent of shapes in the world but were not actual objects in the world,” said study author Carlos Ponce. “We were seeing something that was more like the language cells use with each other.”

This image was evolved by a neuron in the inferotemporal cortex of a monkey using AI. Image Credit: Ponce, Xiao, and Schade et al. – Cell.
Although IT neurons don’t seem to use a simple letter alphabet, it does rely on a vast array of characters like hieroglyphs or Chinese characters, “each loaded with more information,” said Afraz.

The adaptive nature of XDREAM turns it into a powerful tool to probe the inner workings of our brains—particularly for revealing discrepancies between biology and models.

The Science study, led by Dr. James DiCarlo at MIT, takes a similar approach. Using ANNs to generate new patterns and images, the team was able to selectively predict and independently control neuron populations in a high-level visual region called V4.

“So far, what has been done with these models is predicting what the neural responses would be to other stimuli that they have not seen before,” said study author Dr. Pouya Bashivan. “The main difference here is that we are going one step further and using the models to drive the neurons into desired states.”

It suggests that our current ANN models for visual computation “implicitly capture a great deal of visual knowledge” which we can’t really describe, but which the brain uses to turn vision information into perception, the authors said. By testing AI-generated images on biological vision, however, the team concluded that today’s ANNs have a degree of understanding and generalization. The results could potentially help engineer even more accurate ANN models of biological vision, which in turn could feed back into machine vision.

“One thing is clear already: Improved ANN models … have led to control of a high-level neural population that was previously out of reach,” the authors said. “The results presented here have likely only scratched the surface of what is possible with such implemented characterizations of the brain’s neural networks.”

To Afraz, the power of AI here is to find cracks in human perception—both our computational models of sensory processes, as well as our evolved biological software itself. AI can be used “as a perfect adversarial tool to discover design cracks” of IT, said Afraz, such as finding computer art that “fools” a neuron into thinking the object is something else.

“As artificial intelligence researchers develop models that work as well as the brain does—or even better—we will still need to understand which networks are more likely to behave safely and further human goals,” said Ponce. “More efficient AI can be grounded by knowledge of how the brain works.”

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Posted in Human Robots

#434865 5 AI Breakthroughs We’ll Likely See in ...

Posted on April 27, 2019 by Android

Convergence is accelerating disruption… everywhere! Exponential technologies are colliding into each other, reinventing products, services, and industries.

As AI algorithms such as Siri and Alexa can process your voice and output helpful responses, other AIs like Face++ can recognize faces. And yet others create art from scribbles, or even diagnose medical conditions.

Let’s dive into AI and convergence.

Top 5 Predictions for AI Breakthroughs (2019-2024)
My friend Neil Jacobstein is my ‘go-to expert’ in AI, with over 25 years of technical consulting experience in the field. Currently the AI and Robotics chair at Singularity University, Jacobstein is also a Distinguished Visiting Scholar in Stanford’s MediaX Program, a Henry Crown Fellow, an Aspen Institute moderator, and serves on the National Academy of Sciences Earth and Life Studies Committee. Neil predicted five trends he expects to emerge over the next five years, by 2024.

AI gives rise to new non-human pattern recognition and intelligence results

AlphaGo Zero, a machine learning computer program trained to play the complex game of Go, defeated the Go world champion in 2016 by 100 games to zero. But instead of learning from human play, AlphaGo Zero trained by playing against itself—a method known as reinforcement learning.

Building its own knowledge from scratch, AlphaGo Zero demonstrates a novel form of creativity, free of human bias. Even more groundbreaking, this type of AI pattern recognition allows machines to accumulate thousands of years of knowledge in a matter of hours.

While these systems can’t answer the question “What is orange juice?” or compete with the intelligence of a fifth grader, they are growing more and more strategically complex, merging with other forms of narrow artificial intelligence. Within the next five years, who knows what successors of AlphaGo Zero will emerge, augmenting both your business functions and day-to-day life.

Doctors risk malpractice when not using machine learning for diagnosis and treatment planning

A group of Chinese and American researchers recently created an AI system that diagnoses common childhood illnesses, ranging from the flu to meningitis. Trained on electronic health records compiled from 1.3 million outpatient visits of almost 600,000 patients, the AI program produced diagnosis outcomes with unprecedented accuracy.

While the US health system does not tout the same level of accessible universal health data as some Chinese systems, we’ve made progress in implementing AI in medical diagnosis. Dr. Kang Zhang, chief of ophthalmic genetics at the University of California, San Diego, created his own system that detects signs of diabetic blindness, relying on both text and medical images.

With an eye to the future, Jacobstein has predicted that “we will soon see an inflection point where doctors will feel it’s a risk to not use machine learning and AI in their everyday practices because they don’t want to be called out for missing an important diagnostic signal.”

Quantum advantage will massively accelerate drug design and testing

Researchers estimate that there are 1060 possible drug-like molecules—more than the number of atoms in our solar system. But today, chemists must make drug predictions based on properties influenced by molecular structure, then synthesize numerous variants to test their hypotheses.

Quantum computing could transform this time-consuming, highly costly process into an efficient, not to mention life-changing, drug discovery protocol.

“Quantum computing is going to have a major industrial impact… not by breaking encryption,” said Jacobstein, “but by making inroads into design through massive parallel processing that can exploit superposition and quantum interference and entanglement, and that can wildly outperform classical computing.”

AI accelerates security systems’ vulnerability and defense

With the incorporation of AI into almost every aspect of our lives, cyberattacks have grown increasingly threatening. “Deep attacks” can use AI-generated content to avoid both human and AI controls.

Previous examples include fake videos of former President Obama speaking fabricated sentences, and an adversarial AI fooling another algorithm into categorizing a stop sign as a 45 mph speed limit sign. Without the appropriate protections, AI systems can be manipulated to conduct any number of destructive objectives, whether ruining reputations or diverting autonomous vehicles.

Jacobstein’s take: “We all have security systems on our buildings, in our homes, around the healthcare system, and in air traffic control, financial organizations, the military, and intelligence communities. But we all know that these systems have been hacked periodically and we’re going to see that accelerate. So, there are major business opportunities there and there are major opportunities for you to get ahead of that curve before it bites you.”

AI design systems drive breakthroughs in atomically precise manufacturing

Just as the modern computer transformed our relationship with bits and information, AI will redefine and revolutionize our relationship with molecules and materials. AI is currently being used to discover new materials for clean-tech innovations, such as solar panels, batteries, and devices that can now conduct artificial photosynthesis.

Today, it takes about 15 to 20 years to create a single new material, according to industry experts. But as AI design systems skyrocket in capacity, these will vastly accelerate the materials discovery process, allowing us to address pressing issues like climate change at record rates. Companies like Kebotix are already on their way to streamlining the creation of chemistries and materials at the click of a button.

Atomically precise manufacturing will enable us to produce the previously unimaginable.

Final Thoughts
Within just the past three years, countries across the globe have signed into existence national AI strategies and plans for ramping up innovation. Businesses and think tanks have leaped onto the scene, hiring AI engineers and tech consultants to leverage what computer scientist Andrew Ng has even called the new ‘electricity’ of the 21st century.

As AI plays an exceedingly vital role in everyday life, how will your business leverage it to keep up and build forward?

In the wake of burgeoning markets, new ventures will quickly arise, each taking advantage of untapped data sources or unmet security needs.

And as your company aims to ride the wave of AI’s exponential growth, consider the following pointers to leverage AI and disrupt yourself before it reaches you first:

Determine where and how you can begin collecting critical data to inform your AI algorithms
Identify time-intensive processes that can be automated and accelerated within your company
Discern which global challenges can be expedited by hyper-fast, all-knowing minds

Remember: good data is vital fuel. Well-defined problems are the best compass. And the time to start implementing AI is now.

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Posted in Human Robots

#434837 In Defense of Black Box AI

Posted on April 17, 2019 by Android

Deep learning is powering some amazing new capabilities, but we find it hard to scrutinize the workings of these algorithms. Lack of interpretability in AI is a common concern and many are trying to fix it, but is it really always necessary to know what’s going on inside these “black boxes”?

In a recent perspective piece for Science, Elizabeth Holm, a professor of materials science and engineering at Carnegie Mellon University, argued in defense of the black box algorithm. I caught up with her last week to find out more.

Edd Gent: What’s your experience with black box algorithms?

Elizabeth Holm: I got a dual PhD in materials science and engineering and scientific computing. I came to academia about six years ago and part of what I wanted to do in making this career change was to refresh and revitalize my computer science side.

I realized that computer science had changed completely. It used to be about algorithms and making codes run fast, but now it’s about data and artificial intelligence. There are the interpretable methods like random forest algorithms, where we can tell how the machine is making its decisions. And then there are the black box methods, like convolutional neural networks.

Once in a while we can find some information about their inner workings, but most of the time we have to accept their answers and kind of probe around the edges to figure out the space in which we can use them and how reliable and accurate they are.

EG: What made you feel like you had to mount a defense of these black box algorithms?

EH: When I started talking with my colleagues, I found that the black box nature of many of these algorithms was a real problem for them. I could understand that because we’re scientists, we always want to know why and how.

It got me thinking as a bit of a contrarian, “Are black boxes all bad? Must we reject them?” Surely not, because human thought processes are fairly black box. We often rely on human thought processes that the thinker can’t necessarily explain.

It’s looking like we’re going to be stuck with these methods for a while, because they’re really helpful. They do amazing things. And so there’s a very pragmatic realization that these are the best methods we’ve got to do some really important problems, and we’re not right now seeing alternatives that are interpretable. We’re going to have to use them, so we better figure out how.

EG: In what situations do you think we should be using black box algorithms?

EH: I came up with three rules. The simplest rule is: when the cost of a bad decision is small and the value of a good decision is high, it’s worth it. The example I gave in the paper is targeted advertising. If you send an ad no one wants it doesn’t cost a lot. If you’re the receiver it doesn’t cost a lot to get rid of it.

There are cases where the cost is high, and that’s then we choose the black box if it’s the best option to do the job. Things get a little trickier here because we have to ask “what are the costs of bad decisions, and do we really have them fully characterized?” We also have to be very careful knowing that our systems may have biases, they may have limitations in where you can apply them, they may be breakable.

But at the same time, there are certainly domains where we’re going to test these systems so extensively that we know their performance in virtually every situation. And if their performance is better than the other methods, we need to do it. Self driving vehicles are a significant example—it’s almost certain they’re going to have to use black box methods, and that they’re going to end up being better drivers than humans.

The third rule is the more fun one for me as a scientist, and that’s the case where the black box really enlightens us as to a new way to look at something. We have trained a black box to recognize the fracture energy of breaking a piece of metal from a picture of the broken surface. It did a really good job, and humans can’t do this and we don’t know why.

What the computer seems to be seeing is noise. There’s a signal in that noise, and finding it is very difficult, but if we do we may find something significant to the fracture process, and that would be an awesome scientific discovery.

EG: Do you think there’s been too much emphasis on interpretability?

EH: I think the interpretability problem is a fundamental, fascinating computer science grand challenge and there are significant issues where we need to have an interpretable model. But how I would frame it is not that there’s too much emphasis on interpretability, but rather that there’s too much dismissiveness of uninterpretable models.

I think that some of the current social and political issues surrounding some very bad black box outcomes have convinced people that all machine learning and AI should be interpretable because that will somehow solve those problems.

Asking humans to explain their rationale has not eliminated bias, or stereotyping, or bad decision-making in humans. Relying too much on interpreted ability perhaps puts the responsibility in the wrong place for getting better results. I can make a better black box without knowing exactly in what way the first one was bad.

EG: Looking further into the future, do you think there will be situations where humans will have to rely on black box algorithms to solve problems we can’t get our heads around?

EH: I do think so, and it’s not as much of a stretch as we think it is. For example, humans don’t design the circuit map of computer chips anymore. We haven’t for years. It’s not a black box algorithm that designs those circuit boards, but we’ve long since given up trying to understand a particular computer chip’s design.

With the billions of circuits in every computer chip, the human mind can’t encompass it, either in scope or just the pure time that it would take to trace every circuit. There are going to be cases where we want a system so complex that only the patience that computers have and their ability to work in very high-dimensional spaces is going to be able to do it.

So we can continue to argue about interpretability, but we need to acknowledge that we’re going to need to use black boxes. And this is our opportunity to do our due diligence to understand how to use them responsibly, ethically, and with benefits rather than harm. And that’s going to be a social conversation as well as as a scientific one.

*Responses have been edited for length and style

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Posted in Human Robots