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#436188 The Blogger Behind “AI ...

Sure, artificial intelligence is transforming the world’s societies and economies—but can an AI come up with plausible ideas for a Halloween costume?

Janelle Shane has been asking such probing questions since she started her AI Weirdness blog in 2016. She specializes in training neural networks (which underpin most of today’s machine learning techniques) on quirky data sets such as compilations of knitting instructions, ice cream flavors, and names of paint colors. Then she asks the neural net to generate its own contributions to these categories—and hilarity ensues. AI is not likely to disrupt the paint industry with names like “Ronching Blue,” “Dorkwood,” and “Turdly.”

Shane’s antics have a serious purpose. She aims to illustrate the serious limitations of today’s AI, and to counteract the prevailing narrative that describes AI as well on its way to superintelligence and complete human domination. “The danger of AI is not that it’s too smart,” Shane writes in her new book, “but that it’s not smart enough.”

The book, which came out on Tuesday, is called You Look Like a Thing and I Love You. It takes its odd title from a list of AI-generated pick-up lines, all of which would at least get a person’s attention if shouted, preferably by a robot, in a crowded bar. Shane’s book is shot through with her trademark absurdist humor, but it also contains real explanations of machine learning concepts and techniques. It’s a painless way to take AI 101.

She spoke with IEEE Spectrum about the perils of placing too much trust in AI systems, the strange AI phenomenon of “giraffing,” and her next potential Halloween costume.

Janelle Shane on . . .

The un-delicious origin of her blog
“The narrower the problem, the smarter the AI will seem”
Why overestimating AI is dangerous
Giraffing!
Machine and human creativity

The un-delicious origin of her blog IEEE Spectrum: You studied electrical engineering as an undergrad, then got a master’s degree in physics. How did that lead to you becoming the comedian of AI?
Janelle Shane: I’ve been interested in machine learning since freshman year of college. During orientation at Michigan State, a professor who worked on evolutionary algorithms gave a talk about his work. It was full of the most interesting anecdotes–some of which I’ve used in my book. He told an anecdote about people setting up a machine learning algorithm to do lens design, and the algorithm did end up designing an optical system that works… except one of the lenses was 50 feet thick, because they didn’t specify that it couldn’t do that.
I started working in his lab on optics, doing ultra-short laser pulse work. I ended up doing a lot more optics than machine learning, but I always found it interesting. One day I came across a list of recipes that someone had generated using a neural net, and I thought it was hilarious and remembered why I thought machine learning was so cool. That was in 2016, ages ago in machine learning land.
Spectrum: So you decided to “establish weirdness as your goal” for your blog. What was the first weird experiment that you blogged about?
Shane: It was generating cookbook recipes. The neural net came up with ingredients like: “Take ¼ pounds of bones or fresh bread.” That recipe started out: “Brown the salmon in oil, add creamed meat to the mixture.” It was making mistakes that showed the thing had no memory at all.
Spectrum: You say in the book that you can learn a lot about AI by giving it a task and watching it flail. What do you learn?
Shane: One thing you learn is how much it relies on surface appearances rather than deep understanding. With the recipes, for example: It got the structure of title, category, ingredients, instructions, yield at the end. But when you look more closely, it has instructions like “Fold the water and roll it into cubes.” So clearly this thing does not understand water, let alone the other things. It’s recognizing certain phrases that tend to occur, but it doesn’t have a concept that these recipes are describing something real. You start to realize how very narrow the algorithms in this world are. They only know exactly what we tell them in our data set.
BACK TO TOP↑ “The narrower the problem, the smarter the AI will seem” Spectrum: That makes me think of DeepMind’s AlphaGo, which was universally hailed as a triumph for AI. It can play the game of Go better than any human, but it doesn’t know what Go is. It doesn’t know that it’s playing a game.
Shane: It doesn’t know what a human is, or if it’s playing against a human or another program. That’s also a nice illustration of how well these algorithms do when they have a really narrow and well-defined problem.
The narrower the problem, the smarter the AI will seem. If it’s not just doing something repeatedly but instead has to understand something, coherence goes down. For example, take an algorithm that can generate images of objects. If the algorithm is restricted to birds, it could do a recognizable bird. If this same algorithm is asked to generate images of any animal, if its task is that broad, the bird it generates becomes an unrecognizable brown feathered smear against a green background.
Spectrum: That sounds… disturbing.
Shane: It’s disturbing in a weird amusing way. What’s really disturbing is the humans it generates. It hasn’t seen them enough times to have a good representation, so you end up with an amorphous, usually pale-faced thing with way too many orifices. If you asked it to generate an image of a person eating pizza, you’ll have blocks of pizza texture floating around. But if you give that image to an image-recognition algorithm that was trained on that same data set, it will say, “Oh yes, that’s a person eating pizza.”
BACK TO TOP↑ Why overestimating AI is dangerous Spectrum: Do you see it as your role to puncture the AI hype?
Shane: I do see it that way. Not a lot of people are bringing out this side of AI. When I first started posting my results, I’d get people saying, “I don’t understand, this is AI, shouldn’t it be better than this? Why doesn't it understand?” Many of the impressive examples of AI have a really narrow task, or they’ve been set up to hide how little understanding it has. There’s a motivation, especially among people selling products based on AI, to represent the AI as more competent and understanding than it actually is.
Spectrum: If people overestimate the abilities of AI, what risk does that pose?
Shane: I worry when I see people trusting AI with decisions it can’t handle, like hiring decisions or decisions about moderating content. These are really tough tasks for AI to do well on. There are going to be a lot of glitches. I see people saying, “The computer decided this so it must be unbiased, it must be objective.”

“If the algorithm’s task is to replicate human hiring decisions, it’s going to glom onto gender bias and race bias.”
—Janelle Shane, AI Weirdness blogger
That’s another thing I find myself highlighting in the work I’m doing. If the data includes bias, the algorithm will copy that bias. You can’t tell it not to be biased, because it doesn’t understand what bias is. I think that message is an important one for people to understand.
If there’s bias to be found, the algorithm is going to go after it. It’s like, “Thank goodness, finally a signal that’s reliable.” But for a tough problem like: Look at these resumes and decide who’s best for the job. If its task is to replicate human hiring decisions, it’s going to glom onto gender bias and race bias. There’s an example in the book of a hiring algorithm that Amazon was developing that discriminated against women, because the historical data it was trained on had that gender bias.
Spectrum: What are the other downsides of using AI systems that don’t really understand their tasks?
Shane: There is a risk in putting too much trust in AI and not examining its decisions. Another issue is that it can solve the wrong problems, without anyone realizing it. There have been a couple of cases in medicine. For example, there was an algorithm that was trained to recognize things like skin cancer. But instead of recognizing the actual skin condition, it latched onto signals like the markings a surgeon makes on the skin, or a ruler placed there for scale. It was treating those things as a sign of skin cancer. It’s another indication that these algorithms don’t understand what they’re looking at and what the goal really is.
BACK TO TOP↑ Giraffing Spectrum: In your blog, you often have neural nets generate names for things—such as ice cream flavors, paint colors, cats, mushrooms, and types of apples. How do you decide on topics?
Shane: Quite often it’s because someone has written in with an idea or a data set. They’ll say something like, “I’m the MIT librarian and I have a whole list of MIT thesis titles.” That one was delightful. Or they’ll say, “We are a high school robotics team, and we know where there’s a list of robotics team names.” It’s fun to peek into a different world. I have to be careful that I’m not making fun of the naming conventions in the field. But there’s a lot of humor simply in the neural net’s complete failure to understand. Puns in particular—it really struggles with puns.
Spectrum: Your blog is quite absurd, but it strikes me that machine learning is often absurd in itself. Can you explain the concept of giraffing?
Shane: This concept was originally introduced by [internet security expert] Melissa Elliott. She proposed this phrase as a way to describe the algorithms’ tendency to see giraffes way more often than would be likely in the real world. She posted a whole bunch of examples, like a photo of an empty field in which an image-recognition algorithm has confidently reported that there are giraffes. Why does it think giraffes are present so often when they’re actually really rare? Because they’re trained on data sets from online. People tend to say, “Hey look, a giraffe!” And then take a photo and share it. They don’t do that so often when they see an empty field with rocks.
There’s also a chatbot that has a delightful quirk. If you show it some photo and ask it how many giraffes are in the picture, it will always answer with some non zero number. This quirk comes from the way the training data was generated: These were questions asked and answered by humans online. People tended not to ask the question “How many giraffes are there?” when the answer was zero. So you can show it a picture of someone holding a Wii remote. If you ask it how many giraffes are in the picture, it will say two.
BACK TO TOP↑ Machine and human creativity Spectrum: AI can be absurd, and maybe also creative. But you make the point that AI art projects are really human-AI collaborations: Collecting the data set, training the algorithm, and curating the output are all artistic acts on the part of the human. Do you see your work as a human-AI art project?
Shane: Yes, I think there is artistic intent in my work; you could call it literary or visual. It’s not so interesting to just take a pre-trained algorithm that’s been trained on utilitarian data, and tell it to generate a bunch of stuff. Even if the algorithm isn’t one that I’ve trained myself, I think about, what is it doing that’s interesting, what kind of story can I tell around it, and what do I want to show people.

The Halloween costume algorithm “was able to draw on its knowledge of which words are related to suggest things like sexy barnacle.”
—Janelle Shane, AI Weirdness blogger
Spectrum: For the past three years you’ve been getting neural nets to generate ideas for Halloween costumes. As language models have gotten dramatically better over the past three years, are the costume suggestions getting less absurd?
Shane: Yes. Before I would get a lot more nonsense words. This time I got phrases that were related to real things in the data set. I don’t believe the training data had the words Flying Dutchman or barnacle. But it was able to draw on its knowledge of which words are related to suggest things like sexy barnacle and sexy Flying Dutchman.
Spectrum: This year, I saw on Twitter that someone made the gothy giraffe costume happen. Would you ever dress up for Halloween in a costume that the neural net suggested?
Shane: I think that would be fun. But there would be some challenges. I would love to go as the sexy Flying Dutchman. But my ambition may constrict me to do something more like a list of leg parts.
BACK TO TOP↑ Continue reading

Posted in Human Robots

#435614 3 Easy Ways to Evaluate AI Claims

When every other tech startup claims to use artificial intelligence, it can be tough to figure out if an AI service or product works as advertised. In the midst of the AI “gold rush,” how can you separate the nuggets from the fool’s gold?

There’s no shortage of cautionary tales involving overhyped AI claims. And applying AI technologies to health care, education, and law enforcement mean that getting it wrong can have real consequences for society—not just for investors who bet on the wrong unicorn.

So IEEE Spectrum asked experts to share their tips for how to identify AI hype in press releases, news articles, research papers, and IPO filings.

“It can be tricky, because I think the people who are out there selling the AI hype—selling this AI snake oil—are getting more sophisticated over time,” says Tim Hwang, director of the Harvard-MIT Ethics and Governance of AI Initiative.

The term “AI” is perhaps most frequently used to describe machine learning algorithms (and deep learning algorithms, which require even less human guidance) that analyze huge amounts of data and make predictions based on patterns that humans might miss. These popular forms of AI are mostly suited to specialized tasks, such as automatically recognizing certain objects within photos. For that reason, they are sometimes described as “weak” or “narrow” AI.

Some researchers and thought leaders like to talk about the idea of “artificial general intelligence” or “strong AI” that has human-level capacity and flexibility to handle many diverse intellectual tasks. But for now, this type of AI remains firmly in the realm of science fiction and is far from being realized in the real world.

“AI has no well-defined meaning and many so-called AI companies are simply trying to take advantage of the buzz around that term,” says Arvind Narayanan, a computer scientist at Princeton University. “Companies have even been caught claiming to use AI when, in fact, the task is done by human workers.”

Here are three ways to recognize AI hype.

Look for Buzzwords
One red flag is what Hwang calls the “hype salad.” This means stringing together the term “AI” with many other tech buzzwords such as “blockchain” or “Internet of Things.” That doesn’t automatically disqualify the technology, but spotting a high volume of buzzwords in a post, pitch, or presentation should raise questions about what exactly the company or individual has developed.

Other experts agree that strings of buzzwords can be a red flag. That’s especially true if the buzzwords are never really explained in technical detail, and are simply tossed around as vague, poorly-defined terms, says Marzyeh Ghassemi, a computer scientist and biomedical engineer at the University of Toronto in Canada.

“I think that if it looks like a Google search—picture ‘interpretable blockchain AI deep learning medicine’—it's probably not high-quality work,” Ghassemi says.

Hwang also suggests mentally replacing all mentions of “AI” in an article with the term “magical fairy dust.” It’s a way of seeing whether an individual or organization is treating the technology like magic. If so—that’s another good reason to ask more questions about what exactly the AI technology involves.

And even the visual imagery used to illustrate AI claims can indicate that an individual or organization is overselling the technology.

“I think that a lot of the people who work on machine learning on a day-to-day basis are pretty humble about the technology, because they’re largely confronted with how frequently it just breaks and doesn't work,” Hwang says. “And so I think that if you see a company or someone representing AI as a Terminator head, or a big glowing HAL eye or something like that, I think it’s also worth asking some questions.”

Interrogate the Data

It can be hard to evaluate AI claims without any relevant expertise, says Ghassemi at the University of Toronto. Even experts need to know the technical details of the AI algorithm in question and have some access to the training data that shaped the AI model’s predictions. Still, savvy readers with some basic knowledge of applied statistics can search for red flags.

To start, readers can look for possible bias in training data based on small sample sizes or a skewed population that fails to reflect the broader population, Ghassemi says. After all, an AI model trained only on health data from white men would not necessarily achieve similar results for other populations of patients.

“For me, a red flag is not demonstrating deep knowledge of how your labels are defined.”
—Marzyeh Ghassemi, University of Toronto

How machine learning and deep learning models perform also depends on how well humans labeled the sample datasets use to train these programs. This task can be straightforward when labeling photos of cats versus dogs, but gets more complicated when assigning disease diagnoses to certain patient cases.

Medical experts frequently disagree with each other on diagnoses—which is why many patients seek a second opinion. Not surprisingly, this ambiguity can also affect the diagnostic labels that experts assign in training datasets. “For me, a red flag is not demonstrating deep knowledge of how your labels are defined,” Ghassemi says.

Such training data can also reflect the cultural stereotypes and biases of the humans who labeled the data, says Narayanan at Princeton University. Like Ghassemi, he recommends taking a hard look at exactly what the AI has learned: “A good way to start critically evaluating AI claims is by asking questions about the training data.”

Another red flag is presenting an AI system’s performance through a single accuracy figure without much explanation, Narayanan says. Claiming that an AI model achieves “99 percent” accuracy doesn’t mean much without knowing the baseline for comparison—such as whether other systems have already achieved 99 percent accuracy—or how well that accuracy holds up in situations beyond the training dataset.

Narayanan also emphasized the need to ask questions about an AI model’s false positive rate—the rate of making wrong predictions about the presence of a given condition. Even if the false positive rate of a hypothetical AI service is just one percent, that could have major consequences if that service ends up screening millions of people for cancer.

Readers can also consider whether using AI in a given situation offers any meaningful improvement compared to traditional statistical methods, says Clayton Aldern, a data scientist and journalist who serves as managing director for Caldern LLC. He gave the hypothetical example of a “super-duper-fancy deep learning model” that achieves a prediction accuracy of 89 percent, compared to a “little polynomial regression model” that achieves 86 percent on the same dataset.

“We're talking about a three-percentage-point increase on something that you learned about in Algebra 1,” Aldern says. “So is it worth the hype?”

Don’t Ignore the Drawbacks

The hype surrounding AI isn’t just about the technical merits of services and products driven by machine learning. Overblown claims about the beneficial impacts of AI technology—or vague promises to address ethical issues related to deploying it—should also raise red flags.

“If a company promises to use its tech ethically, it is important to question if its business model aligns with that promise,” Narayanan says. “Even if employees have noble intentions, it is unrealistic to expect the company as a whole to resist financial imperatives.”

One example might be a company with a business model that depends on leveraging customers’ personal data. Such companies “tend to make empty promises when it comes to privacy,” Narayanan says. And, if companies hire workers to produce training data, it’s also worth asking whether the companies treat those workers ethically.

The transparency—or lack thereof—about any AI claim can also be telling. A company or research group can minimize concerns by publishing technical claims in peer-reviewed journals or allowing credible third parties to evaluate their AI without giving away big intellectual property secrets, Narayanan says. Excessive secrecy is a big red flag.

With these strategies, you don’t need to be a computer engineer or data scientist to start thinking critically about AI claims. And, Narayanan says, the world needs many people from different backgrounds for societies to fully consider the real-world implications of AI.

Editor’s Note: The original version of this story misspelled Clayton Aldern’s last name as Alderton. Continue reading

Posted in Human Robots

#434658 The Next Data-Driven Healthtech ...

Increasing your healthspan (i.e. making 100 years old the new 60) will depend to a large degree on artificial intelligence. And, as we saw in last week’s blog, healthcare AI systems are extremely data-hungry.

Fortunately, a slew of new sensors and data acquisition methods—including over 122 million wearables shipped in 2018—are bursting onto the scene to meet the massive demand for medical data.

From ubiquitous biosensors, to the mobile healthcare revolution, to the transformative power of the Health Nucleus, converging exponential technologies are fundamentally transforming our approach to healthcare.

In Part 4 of this blog series on Longevity & Vitality, I expand on how we’re acquiring the data to fuel today’s AI healthcare revolution.

In this blog, I’ll explore:

How the Health Nucleus is transforming “sick care” to healthcare
Sensors, wearables, and nanobots
The advent of mobile health

Let’s dive in.

Health Nucleus: Transforming ‘Sick Care’ to Healthcare
Much of today’s healthcare system is actually sick care. Most of us assume that we’re perfectly healthy, with nothing going on inside our bodies, until the day we travel to the hospital writhing in pain only to discover a serious or life-threatening condition.

Chances are that your ailment didn’t materialize that morning; rather, it’s been growing or developing for some time. You simply weren’t aware of it. At that point, once you’re diagnosed as “sick,” our medical system engages to take care of you.

What if, instead of this retrospective and reactive approach, you were constantly monitored, so that you could know the moment anything was out of whack?

Better yet, what if you more closely monitored those aspects of your body that your gene sequence predicted might cause you difficulty? Think: your heart, your kidneys, your breasts. Such a system becomes personalized, predictive, and possibly preventative.

This is the mission of the Health Nucleus platform built by Human Longevity, Inc. (HLI). While not continuous—that will come later, with the next generation of wearable and implantable sensors—the Health Nucleus was designed to ‘digitize’ you once per year to help you determine whether anything is going on inside your body that requires immediate attention.

The Health Nucleus visit provides you with the following tests during a half-day visit:

Whole genome sequencing (30x coverage)
Whole body (non-contrast) MRI
Brain magnetic resonance imaging/angiography (MRI/MRA)
CT (computed tomography) of the heart and lungs
Coronary artery calcium scoring
Electrocardiogram
Echocardiogram
Continuous cardiac monitoring
Clinical laboratory tests and metabolomics

In late 2018, HLI published the results of the first 1,190 clients through the Health Nucleus. The results were eye-opening—especially since these patients were all financially well-off, and already had access to the best doctors.

Following are the physiological and genomic findings in these clients who self-selected to undergo evaluation at HLI’s Health Nucleus.

Physiological Findings [TG]

Two percent had previously unknown tumors detected by MRI
2.5 percent had previously undetected aneurysms detected by MRI
Eight percent had cardiac arrhythmia found on cardiac rhythm monitoring, not previously known
Nine percent had moderate-severe coronary artery disease risk, not previously known
16 percent discovered previously unknown cardiac structure/function abnormalities
30 percent had elevated liver fat, not previously known

Genomic Findings [TG]

24 percent of clients uncovered a rare (unknown) genetic mutation found on WGS
63 percent of clients had a rare genetic mutation with a corresponding phenotypic finding

In summary, HLI’s published results found that 14.4 percent of clients had significant findings that are actionable, requiring immediate or near-term follow-up and intervention.

Long-term value findings were found in 40 percent of the clients we screened. Long-term clinical findings include discoveries that require medical attention or monitoring but are not immediately life-threatening.

The bottom line: most people truly don’t know their actual state of health. The ability to take a fully digital deep dive into your health status at least once per year will enable you to detect disease at stage zero or stage one, when it is most curable.

Sensors, Wearables, and Nanobots
Wearables, connected devices, and quantified self apps will allow us to continuously collect enormous amounts of useful health information.

Wearables like the Quanttus wristband and Vital Connect can transmit your electrocardiogram data, vital signs, posture, and stress levels anywhere on the planet.

In April 2017, we were proud to grant $2.5 million in prize money to the winning team in the Qualcomm Tricorder XPRIZE, Final Frontier Medical Devices.

Using a group of noninvasive sensors that collect data on vital signs, body chemistry, and biological functions, Final Frontier integrates this data in their powerful, AI-based DxtER diagnostic engine for rapid, high-precision assessments.

Their engine combines learnings from clinical emergency medicine and data analysis from actual patients.

Google is developing a full range of internal and external sensors (e.g. smart contact lenses) that can monitor the wearer’s vitals, ranging from blood sugar levels to blood chemistry.

In September 2018, Apple announced its Series 4 Apple Watch, including an FDA-approved mobile, on-the-fly ECG. Granted its first FDA approval, Apple appears to be moving deeper into the sensing healthcare market.

Further, Apple is reportedly now developing sensors that can non-invasively monitor blood sugar levels in real time for diabetic treatment. IoT-connected sensors are also entering the world of prescription drugs.

Last year, the FDA approved the first sensor-embedded pill, Abilify MyCite. This new class of digital pills can now communicate medication data to a user-controlled app, to which doctors may be granted access for remote monitoring.

Perhaps what is most impressive about the next generation of wearables and implantables is the density of sensors, processing, networking, and battery capability that we can now cheaply and compactly integrate.

Take the second-generation OURA ring, for example, which focuses on sleep measurement and management.

The OURA ring looks like a slightly thick wedding band, yet contains an impressive array of sensors and capabilities, including:

Two infrared LED
One infrared sensor
Three temperature sensors
One accelerometer
A six-axis gyro
A curved battery with a seven-day life
The memory, processing, and transmission capability required to connect with your smartphone

Disrupting Medical Imaging Hardware
In 2018, we saw lab breakthroughs that will drive the cost of an ultrasound sensor to below $100, in a packaging smaller than most bandages, powered by a smartphone. Dramatically disrupting ultrasound is just the beginning.

Nanobots and Nanonetworks
While wearables have long been able to track and transmit our steps, heart rate, and other health data, smart nanobots and ingestible sensors will soon be able to monitor countless new parameters and even help diagnose disease.

Some of the most exciting breakthroughs in smart nanotechnology from the past year include:

Researchers from the École Polytechnique Fédérale de Lausanne (EPFL) and the Swiss Federal Institute of Technology in Zurich (ETH Zurich) demonstrated artificial microrobots that can swim and navigate through different fluids, independent of additional sensors, electronics, or power transmission.

Researchers at the University of Chicago proposed specific arrangements of DNA-based molecular logic gates to capture the information contained in the temporal portion of our cells’ communication mechanisms. Accessing the otherwise-lost time-dependent information of these cellular signals is akin to knowing the tune of a song, rather than solely the lyrics.

MIT researchers built micron-scale robots able to sense, record, and store information about their environment. These tiny robots, about 100 micrometers in diameter (approximately the size of a human egg cell), can also carry out pre-programmed computational tasks.

Engineers at University of California, San Diego developed ultrasound-powered nanorobots that swim efficiently through your blood, removing harmful bacteria and the toxins they produce.

But it doesn’t stop there.

As nanosensor and nanonetworking capabilities develop, these tiny bots may soon communicate with each other, enabling the targeted delivery of drugs and autonomous corrective action.

Mobile Health
The OURA ring and the Series 4 Apple Watch are just the tip of the spear when it comes to our future of mobile health. This field, predicted to become a $102 billion market by 2022, puts an on-demand virtual doctor in your back pocket.

Step aside, WebMD.

In true exponential technology fashion, mobile device penetration has increased dramatically, while image recognition error rates and sensor costs have sharply declined.

As a result, AI-powered medical chatbots are flooding the market; diagnostic apps can identify anything from a rash to diabetic retinopathy; and with the advent of global connectivity, mHealth platforms enable real-time health data collection, transmission, and remote diagnosis by medical professionals.

Already available to residents across North London, Babylon Health offers immediate medical advice through AI-powered chatbots and video consultations with doctors via its app.

Babylon now aims to build up its AI for advanced diagnostics and even prescription. Others, like Woebot, take on mental health, using cognitive behavioral therapy in communications over Facebook messenger with patients suffering from depression.

In addition to phone apps and add-ons that test for fertility or autism, the now-FDA-approved Clarius L7 Linear Array Ultrasound Scanner can connect directly to iOS and Android devices and perform wireless ultrasounds at a moment’s notice.

Next, Healthy.io, an Israeli startup, uses your smartphone and computer vision to analyze traditional urine test strips—all you need to do is take a few photos.

With mHealth platforms like ClickMedix, which connects remotely-located patients to medical providers through real-time health data collection and transmission, what’s to stop us from delivering needed treatments through drone delivery or robotic telesurgery?

Welcome to the age of smartphone-as-a-medical-device.

Conclusion
With these DIY data collection and diagnostic tools, we save on transportation costs (time and money), and time bottlenecks.

No longer will you need to wait for your urine or blood results to go through the current information chain: samples will be sent to the lab, analyzed by a technician, results interpreted by your doctor, and only then relayed to you.

Just like the “sage-on-the-stage” issue with today’s education system, healthcare has a “doctor-on-the-dais” problem. Current medical procedures are too complicated and expensive for a layperson to perform and analyze on their own.

The coming abundance of healthcare data promises to transform how we approach healthcare, putting the power of exponential technologies in the patient’s hands and revolutionizing how we live.

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Posted in Human Robots

#434532 How Microrobots Will Fix Our Roads and ...

Swarms of microrobots will scuttle along beneath our roads and pavements, finding and fixing leaky pipes and faulty cables. Thanks to their efforts, we can avoid costly road work that costs billions of dollars each year—not to mention frustrating traffic delays.

That is, if a new project sponsored by the U.K. government is a success. Recent developments in the space seem to point towards a bright future for microrobots.

Microrobots Saving Billions
Each year, around 1.5 million road excavations take place across the U.K. Many are due to leaky pipes and faulty cables that necessitate excavation of road surfaces in order to fix them. The resulting repairs, alongside disruptions to traffic and businesses, are estimated to cost a whopping £6.3 billion ($8 billion).

A consortium of scientists, led by University of Sheffield Professor Kirill Horoshenkov, are planning to use microrobots to negate most of these costs. The group has received a £7.2 million ($9.2 million) grant to develop and build their bots.

According to Horoshenkov, the microrobots will come in two versions. One is an inspection bot, which will navigate along underground infrastructure and examine its condition via sonar. The inspectors will be complemented by worker bots capable of carrying out repairs with cement and adhesives or cleaning out blockages with a high-powered jet. The inspector bots will be around one centimeter long and possibly autonomous, while the worker bots will be slightly larger and steered via remote control.

If successful, it is believed the bots could potentially save the U.K. economy around £5 billion ($6.4 billion) a year.

The U.K. government has set aside a further £19 million ($24 million) for research into robots for hazardous environments, such as nuclear decommissioning, drones for oil pipeline monitoring, and artificial intelligence software to detect the need for repairs on satellites in orbit.

The Lowest-Hanging Fruit
Microrobots like the ones now under development in the U.K. have many potential advantages and use cases. Thanks to their small size they can navigate tight spaces, for example in search and rescue operations, and robot swarm technology would allow them to collaborate to perform many different functions, including in construction projects.

To date, the number of microrobots in use is relatively limited, but that could be about to change, with bots closing in on other types of inspection jobs, which could be considered one of the lowest-hanging fruits.

Engineering firm Rolls-Royce (not the car company, but the one that builds aircraft engines) is looking to use microrobots to inspect some of the up to 25,000 individual parts that make up an engine. The microrobots use the cockroach as a model, and Rolls Royce believes they could save engineers time when performing the maintenance checks that can take over a month per engine.

Even Smaller Successes
Going further down in scale, recent years have seen a string of successes for nanobots. For example, a team of researchers at the Femto-ST Institute have used nanobots to build what is likely the world’s smallest house (if this isn’t a category at Guinness, someone needs to get on the phone with them), which stands a ‘towering’ 0.015 millimeters.

One of the areas where nanobots have shown great promise is in medicine. Several studies have shown how the minute bots are capable of delivering drugs directly into dense biological tissue, which can otherwise be highly challenging to target directly. Such delivery systems have a great potential for improving the treatment of a wide range of ailments and illnesses, including cancer.

There’s no question that the ecosystem of microrobots and nanobots is evolving. While still in their early days, the above successes point to a near-future boom in the bots we may soon refer to as our ‘littlest everyday helpers.’

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#434151 Life-or-Death Algorithms: The Black Box ...

When it comes to applications for machine learning, few can be more widely hyped than medicine. This is hardly surprising: it’s a huge industry that generates a phenomenal amount of data and revenue, where technological advances can improve or save the lives of millions of people. Hardly a week passes without a study that suggests algorithms will soon be better than experts at detecting pneumonia, or Alzheimer’s—diseases in complex organs ranging from the eye to the heart.

The problems of overcrowded hospitals and overworked medical staff plague public healthcare systems like Britain’s NHS and lead to rising costs for private healthcare systems. Here, again, algorithms offer a tantalizing solution. How many of those doctor’s visits really need to happen? How many could be replaced by an interaction with an intelligent chatbot—especially if it can be combined with portable diagnostic tests, utilizing the latest in biotechnology? That way, unnecessary visits could be reduced, and patients could be diagnosed and referred to specialists more quickly without waiting for an initial consultation.

As ever with artificial intelligence algorithms, the aim is not to replace doctors, but to give them tools to reduce the mundane or repetitive parts of the job. With an AI that can examine thousands of scans in a minute, the “dull drudgery” is left to machines, and the doctors are freed to concentrate on the parts of the job that require more complex, subtle, experience-based judgement of the best treatments and the needs of the patient.

High Stakes
But, as ever with AI algorithms, there are risks involved with relying on them—even for tasks that are considered mundane. The problems of black-box algorithms that make inexplicable decisions are bad enough when you’re trying to understand why that automated hiring chatbot was unimpressed by your job interview performance. In a healthcare context, where the decisions made could mean life or death, the consequences of algorithmic failure could be grave.

A new paper in Science Translational Medicine, by Nicholson Price, explores some of the promises and pitfalls of using these algorithms in the data-rich medical environment.

Neural networks excel at churning through vast quantities of training data and making connections, absorbing the underlying patterns or logic for the system in hidden layers of linear algebra; whether it’s detecting skin cancer from photographs or learning to write in pseudo-Shakespearean script. They are terrible, however, at explaining the underlying logic behind the relationships that they’ve found: there is often little more than a string of numbers, the statistical “weights” between the layers. They struggle to distinguish between correlation and causation.

This raises interesting dilemmas for healthcare providers. The dream of big data in medicine is to feed a neural network on “huge troves of health data, finding complex, implicit relationships and making individualized assessments for patients.” What if, inevitably, such an algorithm proves to be unreasonably effective at diagnosing a medical condition or prescribing a treatment, but you have no scientific understanding of how this link actually works?

Too Many Threads to Unravel?
The statistical models that underlie such neural networks often assume that variables are independent of each other, but in a complex, interacting system like the human body, this is not always the case.

In some ways, this is a familiar concept in medical science—there are many phenomena and links which have been observed for decades but are still poorly understood on a biological level. Paracetamol is one of the most commonly-prescribed painkillers, but there’s still robust debate about how it actually works. Medical practitioners may be keen to deploy whatever tool is most effective, regardless of whether it’s based on a deeper scientific understanding. Fans of the Copenhagen interpretation of quantum mechanics might spin this as “Shut up and medicate!”

But as in that field, there’s a debate to be had about whether this approach risks losing sight of a deeper understanding that will ultimately prove more fruitful—for example, for drug discovery.

Away from the philosophical weeds, there are more practical problems: if you don’t understand how a black-box medical algorithm is operating, how should you approach the issues of clinical trials and regulation?

Price points out that, in the US, the “21st-Century Cures Act” allows the FDA to regulate any algorithm that analyzes images, or doesn’t allow a provider to review the basis for its conclusions: this could completely exclude “black-box” algorithms of the kind described above from use.

Transparency about how the algorithm functions—the data it looks at, and the thresholds for drawing conclusions or providing medical advice—may be required, but could also conflict with the profit motive and the desire for secrecy in healthcare startups.

One solution might be to screen algorithms that can’t explain themselves, or don’t rely on well-understood medical science, from use before they enter the healthcare market. But this could prevent people from reaping the benefits that they can provide.

Evaluating Algorithms
New healthcare algorithms will be unable to do what physicists did with quantum mechanics, and point to a track record of success, because they will not have been deployed in the field. And, as Price notes, many algorithms will improve as they’re deployed in the field for a greater amount of time, and can harvest and learn from the performance data that’s actually used. So how can we choose between the most promising approaches?

Creating a standardized clinical trial and validation system that’s equally valid across algorithms that function in different ways, or use different input or training data, will be a difficult task. Clinical trials that rely on small sample sizes, such as for algorithms that attempt to personalize treatment to individuals, will also prove difficult. With a small sample size and little scientific understanding, it’s hard to tell whether the algorithm succeeded or failed because it’s bad at its job or by chance.

Add learning into the mix and the picture gets more complex. “Perhaps more importantly, to the extent that an ideal black-box algorithm is plastic and frequently updated, the clinical trial validation model breaks down further, because the model depends on a static product subject to stable validation.” As Price describes, the current system for testing and validation of medical products needs some adaptation to deal with this new software before it can successfully test and validate the new algorithms.

Striking a Balance
The story in healthcare reflects the AI story in so many other fields, and the complexities involved perhaps illustrate why even an illustrious company like IBM appears to be struggling to turn its famed Watson AI into a viable product in the healthcare space.

A balance must be struck, both in our rush to exploit big data and the eerie power of neural networks, and to automate thinking. We must be aware of the biases and flaws of this approach to problem-solving: to realize that it is not a foolproof panacea.

But we also need to embrace these technologies where they can be a useful complement to the skills, insights, and deeper understanding that humans can provide. Much like a neural network, our industries need to train themselves to enhance this cooperation in the future.

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