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#439105 This Robot Taught Itself to Walk in a ...

Recently, in a Berkeley lab, a robot called Cassie taught itself to walk, a little like a toddler might. Through trial and error, it learned to move in a simulated world. Then its handlers sent it strolling through a minefield of real-world tests to see how it’d fare.

And, as it turns out, it fared pretty damn well. With no further fine-tuning, the robot—which is basically just a pair of legs—was able to walk in all directions, squat down while walking, right itself when pushed off balance, and adjust to different kinds of surfaces.

It’s the first time a machine learning approach known as reinforcement learning has been so successfully applied in two-legged robots.

This likely isn’t the first robot video you’ve seen, nor the most polished.

For years, the internet has been enthralled by videos of robots doing far more than walking and regaining their balance. All that is table stakes these days. Boston Dynamics, the heavyweight champ of robot videos, regularly releases mind-blowing footage of robots doing parkour, back flips, and complex dance routines. At times, it can seem the world of iRobot is just around the corner.

This sense of awe is well-earned. Boston Dynamics is one of the world’s top makers of advanced robots.

But they still have to meticulously hand program and choreograph the movements of the robots in their videos. This is a powerful approach, and the Boston Dynamics team has done incredible things with it.

In real-world situations, however, robots need to be robust and resilient. They need to regularly deal with the unexpected, and no amount of choreography will do. Which is how, it’s hoped, machine learning can help.

Reinforcement learning has been most famously exploited by Alphabet’s DeepMind to train algorithms that thrash humans at some the most difficult games. Simplistically, it’s modeled on the way we learn. Touch the stove, get burned, don’t touch the damn thing again; say please, get a jelly bean, politely ask for another.

In Cassie’s case, the Berkeley team used reinforcement learning to train an algorithm to walk in a simulation. It’s not the first AI to learn to walk in this manner. But going from simulation to the real world doesn’t always translate.

Subtle differences between the two can (literally) trip up a fledgling robot as it tries out its sim skills for the first time.

To overcome this challenge, the researchers used two simulations instead of one. The first simulation, an open source training environment called MuJoCo, was where the algorithm drew upon a large library of possible movements and, through trial and error, learned to apply them. The second simulation, called Matlab SimMechanics, served as a low-stakes testing ground that more precisely matched real-world conditions.

Once the algorithm was good enough, it graduated to Cassie.

And amazingly, it didn’t need further polishing. Said another way, when it was born into the physical world—it knew how to walk just fine. In addition, it was also quite robust. The researchers write that two motors in Cassie’s knee malfunctioned during the experiment, but the robot was able to adjust and keep on trucking.

Other labs have been hard at work applying machine learning to robotics.

Last year Google used reinforcement learning to train a (simpler) four-legged robot. And OpenAI has used it with robotic arms. Boston Dynamics, too, will likely explore ways to augment their robots with machine learning. New approaches—like this one aimed at training multi-skilled robots or this one offering continuous learning beyond training—may also move the dial. It’s early yet, however, and there’s no telling when machine learning will exceed more traditional methods.

And in the meantime, Boston Dynamics bots are testing the commercial waters.

Still, robotics researchers, who were not part of the Berkeley team, think the approach is promising. Edward Johns, head of Imperial College London’s Robot Learning Lab, told MIT Technology Review, “This is one of the most successful examples I have seen.”

The Berkeley team hopes to build on that success by trying out “more dynamic and agile behaviors.” So, might a self-taught parkour-Cassie be headed our way? We’ll see.

Image Credit: University of California Berkeley Hybrid Robotics via YouTube Continue reading

Posted in Human Robots

#439077 How Scientists Grew Human Muscles in Pig ...

The little pigs bouncing around the lab looked exceedingly normal. Yet their adorable exterior hid a remarkable secret: each piglet carried two different sets of genes. For now, both sets came from their own species. But one day, one of those sets may be human.

The piglets are chimeras—creatures with intermingled sets of genes, as if multiple entities were seamlessly mashed together. Named after the Greek lion-goat-serpent monsters, chimeras may hold the key to an endless supply of human organs and tissues for transplant. The crux is growing these human parts in another animal—one close enough in size and function to our own.

Last week, a team from the University of Minnesota unveiled two mind-bending chimeras. One was joyous little piglets, each propelled by muscles grown from a different pig. Another was pig embryos, transplanted into surrogate pigs, that developed human muscles for more than 20 days.

The study, led by Drs. Mary and Daniel Garry at the University of Minnesota, had a therapeutic point: engineering a brilliant way to replace muscle loss, especially for the muscles around our skeletons that allow us to move and navigate the world. Trauma and injury, such as from firearm wounds or car crashes, can damage muscle tissue beyond the point of repair. Unfortunately, muscles are also stubborn in that donor tissue from cadavers doesn’t usually “take” at the injury site. For now, there are no effective treatments for severe muscle death, called volumetric muscle loss.

The new human-pig hybrids are designed to tackle this problem. Muscle wasting aside, the study also points to a clever “hack” that increases the amount of human tissue inside a growing pig embryo.

If further improved, the technology could “provide an unlimited supply of organs for transplantation,” said Dr. Mary Garry to Inverse. What’s more, because the human tissue can be sourced from patients themselves, the risk of rejection by the immune system is relatively low—even when grown inside a pig.

“The shortage of organs for heart transplantation, vascular grafting, and skeletal muscle is staggering,” said Garry. Human-animal chimeras could have a “seismic impact” that transforms organ transplantation and helps solve the organ shortage crisis.

That is, if society accepts the idea of a semi-humanoid pig.

Wait…But How?
The new study took a page from previous chimera recipes.

The main ingredients and steps go like this: first, you need an embryo that lacks the ability to develop a tissue or organ. This leaves an “empty slot” of sorts that you can fill with another set of genes—pig, human, or even monkey.

Second, you need to fine-tune the recipe so that the embryos “take” the new genes, incorporating them into their bodies as if they were their own. Third, the new genes activate to instruct the growing embryo to make the necessary tissue or organs without harming the overall animal. Finally, the foreign genes need to stay put, without cells migrating to another body part—say, the brain.

Not exactly straightforward, eh? The piglets are technological wonders that mix cutting-edge gene editing with cloning technologies.

The team went for two chimeras: one with two sets of pig genes, the other with a pig and human mix. Both started with a pig embryo that can’t make its own skeletal muscles (those are the muscles surrounding your bones). Using CRISPR, the gene-editing Swiss Army Knife, they snipped out three genes that are absolutely necessary for those muscles to develop. Like hitting a bullseye with three arrows simultaneously, it’s already a technological feat.

Here’s the really clever part: the muscles around your bones have a slightly different genetic makeup than the ones that line your blood vessels or the ones that pump your heart. While the resulting pig embryos had severe muscle deformities as they developed, their hearts beat as normal. This means the gene editing cut only impacted skeletal muscles.

Then came step two: replacing the missing genes. Using a microneedle, the team injected a fertilized and slightly developed pig egg—called a blastomere—into the embryo. If left on its natural course, a blastomere eventually develops into another embryo. This step “smashes” the two sets of genes together, with the newcomer filling the muscle void. The hybrid embryo was then placed into a surrogate, and roughly four months later, chimeric piglets were born.

Equipped with foreign DNA, the little guys nevertheless seemed totally normal, nosing around the lab and running everywhere without obvious clumsy stumbles. Under the microscope, their “xenomorph” muscles were indistinguishable from run-of-the-mill average muscle tissue—no signs of damage or inflammation, and as stretchy and tough as muscles usually are. What’s more, the foreign DNA seemed to have only developed into muscles, even though they were prevalent across the body. Extensive fishing experiments found no trace of the injected set of genes inside blood vessels or the brain.

A Better Human-Pig Hybrid
Confident in their recipe, the team next repeated the experiment with human cells, with a twist. Instead of using controversial human embryonic stem cells, which are obtained from aborted fetuses, they relied on induced pluripotent stem cells (iPSCs). These are skin cells that have been reverted back into a stem cell state.

Unlike previous attempts at making human chimeras, the team then scoured the genetic landscape of how pig and human embryos develop to find any genetic “brakes” that could derail the process. One gene, TP53, stood out, which was then promptly eliminated with CRISPR.

This approach provides a way for future studies to similarly increase the efficiency of interspecies chimeras, the team said.

The human-pig embryos were then carefully grown inside surrogate pigs for less than a month, and extensively analyzed. By day 20, the hybrids had already grown detectable human skeletal muscle. Similar to the pig-pig chimeras, the team didn’t detect any signs that the human genes had sprouted cells that would eventually become neurons or other non-muscle cells.

For now, human-animal chimeras are not allowed to grow to term, in part to stem the theoretical possibility of engineering humanoid hybrid animals (shudder). However, a sentient human-pig chimera is something that the team specifically addressed. Through multiple experiments, they found no trace of human genes in the embryos’ brain stem cells 20 and 27 days into development. Similarly, human donor genes were absent in cells that would become the hybrid embryos’ reproductive cells.

Despite bioethical quandaries and legal restrictions, human-animal chimeras have taken off, both as a source of insight into human brain development and a well of personalized organs and tissues for transplant. In 2019, Japan lifted its ban on developing human brain cells inside animal embryos, as well as the term limit—to global controversy. There’s also the question of animal welfare, given that hybrid clones will essentially become involuntary organ donors.

As the debates rage on, scientists are nevertheless pushing the limits of human-animal chimeras, while treading as carefully as possible.

“Our data…support the feasibility of the generation of these interspecies chimeras, which will serve as a model for translational research or, one day, as a source for xenotransplantation,” the team said.

Image Credit: Christopher Carson on Unsplash Continue reading

Posted in Human Robots

#439062 Xenobots 2.0: These Living Robots ...

The line between animals and machines was already getting blurry after a team of scientists and roboticists unveiled the first living robots last year. Now the same team has released version 2.0 of their so-called xenobots, and they’re faster, stronger, and more capable than ever.

In January 2020, researchers from Tufts University and the University of Vermont laid out a method for building tiny biological machines out of the eggs of the African claw frog Xenopus laevis. Dubbed xenobots after their animal forebear, they could move independently, push objects, and even team up to create swarms.

Remarkably, building them involved no genetic engineering. Instead, the team used an evolutionary algorithm running on a supercomputer to test out thousands of potential designs made up of different configurations of cells.

Once they’d found some promising candidates that could solve the tasks they were interested in, they used microsurgical tools to build real-world versions out of living cells. The most promising design was built by splicing heart muscle cells (which could contract to propel the xenobots), and skin cells (which provided a rigid support).

Impressive as that might sound, having to build each individual xenobot by hand is obviously tedious. But now the team has devised a new approach that works from the bottom up by getting the xenobots to self-assemble their bodies from single cells. Not only is the approach more scalable, the new xenobots are faster, live longer, and even have a rudimentary memory.

In a paper in Science Robotics, the researchers describe how they took stem cells from frog embryos and allowed them to grow into clumps of several thousand cells called spheroids. After a few days, the stem cells had turned into skin cells covered in small hair-like projections called cilia, which wriggle back and forth.

Normally, these structures are used to spread mucus around on the frog’s skin. But when divorced from their normal context they took on a function more similar to that seen in microorganisms, which use cilia to move about by acting like tiny paddles.

“We are witnessing the remarkable plasticity of cellular collectives, which build a rudimentary new ‘body’ that is quite distinct from their default—in this case, a frog—despite having a completely normal genome,” corresponding author Michael Levin from Tufts University said in a press release.

“We see that cells can re-purpose their genetically encoded hardware, like cilia, for new functions such as locomotion. It is amazing that cells can spontaneously take on new roles and create new body plans and behaviors without long periods of evolutionary selection for those features,” he said.

Not only were the new xenobots faster and longer-lived, they were also much better at tasks like working together as a swarm to gather piles of iron oxide particles. And while the form and function of the xenobots was achieved without any genetic engineering, in an extra experiment the team injected them with RNA that caused them to produce a fluorescent protein that changes color when exposed to a particular color of light.

This allowed the xenobots to record whether they had come into contact with a specific light source while traveling about. The researchers say this is a proof of principle that the xenobots can be imbued with a molecular memory, and future work could allow them to record multiple stimuli and potentially even react to them.

What exactly these xenobots could eventually be used for is still speculative, but they have features that make them a promising alternative to non-organic alternatives. For a start, robots made of stem cells are completely biodegradable and also have their own power source in the form of “yolk platelets” found in all amphibian embryos. They are also able to self-heal in as little as five minutes if cut, and can take advantage of cells’ ability to process all kinds of chemicals.

That suggests they could have applications in everything from therapeutics to environmental engineering. But the researchers also hope to use them to better understand the processes that allow individual cells to combine and work together to create a larger organism, and how these processes might be harnessed and guided for regenerative medicine.

As these animal-machine hybrids advance, they are sure to raise ethical concerns and question marks over the potential risks. But it looks like the future of robotics could be a lot more wet and squishy than we imagined.

Image Credit: Doug Blackiston/Tufts University Continue reading

Posted in Human Robots

#439010 Video Friday: Nanotube-Powered Insect ...

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

HRI 2021 – March 8-11, 2021 – [Online Conference]
RoboSoft 2021 – April 12-16, 2021 – [Online Conference]
ICRA 2021 – May 30-5, 2021 – Xi'an, China
Let us know if you have suggestions for next week, and enjoy today's videos.

If you’ve ever swatted a mosquito away from your face, only to have it return again (and again and again), you know that insects can be remarkably acrobatic and resilient in flight. Those traits help them navigate the aerial world, with all of its wind gusts, obstacles, and general uncertainty. Such traits are also hard to build into flying robots, but MIT Assistant Professor Kevin Yufeng Chen has built a system that approaches insects’ agility.

Chen’s actuators can flap nearly 500 times per second, giving the drone insect-like resilience. “You can hit it when it’s flying, and it can recover,” says Chen. “It can also do aggressive maneuvers like somersaults in the air.” And it weighs in at just 0.6 grams, approximately the mass of a large bumble bee. The drone looks a bit like a tiny cassette tape with wings, though Chen is working on a new prototype shaped like a dragonfly.

[ MIT ]

National Robotics Week is April 3-11, 2021!

[ NRW ]

This is in a motion capture environment, but still, super impressive!

[ Paper ]

Thanks Fan!

Why wait for Boston Dynamics to add an arm to your Spot if you can just do it yourself?

[ ETHZ ]

This video shows the deep-sea free swimming of soft robot in the South China Sea. The soft robot was grasped by a robotic arm on ‘HAIMA’ ROV and reached the bottom of the South China Sea (depth of 3,224 m). After the releasing, the soft robot was actuated with an on-board AC voltage of 8 kV at 1 Hz and demonstrated free swimming locomotion with its flapping fins.

Um, did they bring it back?

[ Nature ]

Quadruped Yuki Mini is 12 DOF robot equipped with a Raspberry Pi that runs ROS. Also, BUNNIES!

[ Lingkang Zhang ]

Thanks Lingkang!

Deployment of drone swarms usually relies on inter-agent communication or visual markers that are mounted on the vehicles to simplify their mutual detection. The vswarm package enables decentralized vision-based control of drone swarms without relying on inter-agent communication or visual fiducial markers. The results show that the drones can safely navigate in an outdoor environment despite substantial background clutter and difficult lighting conditions.

[ Vswarm ]

A conventional adopted method for operating a waiter robot is based on the static position control, where pre-defined goal positions are marked on a map. However, this solution is not optimal in a dynamic setting, such as in a coffee shop or an outdoor catering event, because the customers often change their positions. We explore an alternative human-robot interface design where a human operator communicates the identity of the customer to the robot instead. Inspired by how [a] human communicates, we propose a framework for communicating a visual goal to the robot, through interactive two-way communications.

[ Paper ]

Thanks Poramate!

In this video, LOLA reacts to undetected ground height changes, including a drop and leg-in-hole experiment. Further tests show the robustness to vertical disturbances using a seesaw. The robot is technically blind, not using any camera-based or prior information on the terrain.

[ TUM ]

RaiSim is a cross-platform multi-body physics engine for robotics and AI. It fully supports Linux, Mac OS, and Windows.

[ RaiSim ]

Thanks Fan!

The next generation of LoCoBot is here. The LoCoBot is an ROS research rover for mapping, navigation and manipulation (optional) that enables researchers, educators and students alike to focus on high level code development instead of hardware and building out lower level code. Development on the LoCoBot is simplified with open source software, full ROS-mapping and navigation packages and modular opensource Python API that allows users to move the platform as well as (optional) manipulator in as few as 10 lines of code.

[ Trossen ]

MIT Media Lab Research Specialist Dr. Kate Darling looks at how robots are portrayed in popular film and TV shows.

Kate's book, The New Breed: What Our History with Animals Reveals about Our Future with Robots can be pre-ordered now and comes out next month.

[ Kate Darling ]

The current autonomous mobility systems for planetary exploration are wheeled rovers, limited to flat, gently-sloping terrains and agglomerate regolith. These vehicles cannot tolerate instability and operate within a low-risk envelope (i.e., low-incline driving to avoid toppling). Here, we present ‘Mars Dogs’ (MD), four-legged robotic dogs, the next evolution of extreme planetary exploration.

[ Team CoSTAR ]

In 2020, first-year PhD students at the MIT Media Lab were tasked with a special project—to reimagine the Lab and write sci-fi stories about the MIT Media Lab in the year 2050. “But, we are researchers. We don't only write fiction, we also do science! So, we did what scientists do! We used a secret time machine under the MIT dome to go to the year 2050 and see what’s going on there! Luckily, the Media Lab still exists and we met someone…really cool!” Enjoy this interview of Cyber Joe, AI Mentor for MIT Media Lab Students of 2050.

[ MIT ]

In this talk, we will give an overview of the diverse research we do at CSIRO’s Robotics and Autonomous Systems Group and delve into some specific technologies we have developed including SLAM and Legged robotics. We will also give insights into CSIRO’s participation in the current DARPA Subterranean Challenge where we are deploying a fleet of heterogeneous robots into GPS-denied unknown underground environments.

[ GRASP Seminar ]

Marco Hutter (ETH) and Hae-Won Park (KAIST) talk about “Robotics Inspired by Nature.”

[ Swiss-Korean Science Club ]

Thanks Fan!

In this keynote, Guy Hoffman Assistant Professor and the Mills Family Faculty Fellow in the Sibley School of Mechanical and Aerospace Engineering at Cornell University, discusses “The Social Uncanny of Robotic Companions.”

[ Designerly HRI ] Continue reading

Posted in Human Robots

#438886 This Week’s Awesome Tech Stories From ...

ARTIFICIAL INTELLIGENCE
This Chip for AI Works Using Light, Not Electrons
Will Knight | Wired
“As demand for artificial intelligence grows, so does hunger for the computer power needed to keep AI running. Lightmatter, a startup born at MIT, is betting that AI’s voracious hunger will spawn demand for a fundamentally different kind of computer chip—one that uses light to perform key calculations. ‘Either we invent new kinds of computers to continue,’ says Lightmatter CEO Nick Harris, ‘or AI slows down.’i”

BIOTECH
With This CAD for Genomes, You Can Design New Organisms
Eliza Strickland | IEEE Spectrum
“Imagine being able to design a new organism as easily as you can design a new integrated circuit. That’s the ultimate vision behind the computer-aided design (CAD) program being developed by the GP-write consortium. ‘We’re taking the same things we’d do for design automation in electronics, and applying them to biology,’ says Doug Densmore, an associate professor of electrical and computer engineering at Boston University.”

BIOLOGY
Hey, So These Sea Slugs Decapitate Themselves and Grow New Bodies
Matt Simon | Wired
“That’s right: It pulled a Deadpool. Just a few hours after its self-decapitation, the head began dragging itself around to feed. After a day, the neck wound had closed. After a week, it started to regenerate a heart. In less than a month, the whole body had grown back, and the disembodied slug was embodied once more.”

INTERNET
Move Over, Deep Nostalgia, This AI App Can Make Kim Jong-un Sing ‘I Will Survive’
Helen Sullivan | The Guardian
“If you’ve ever wanted to know what it might be like to see Kim Jong-un let loose at karaoke, your wish has been granted, thanks to an app that lets users turn photographs of anyone—or anything remotely resembling a face—into uncanny AI-powered videos of them lip syncing famous songs.”

ENERGY
GM Unveils Plans for Lithium-Metal Batteries That Could Boost EV Range
Steve Dent | Engadget
“GM has released more details about its next-generation Ultium batteries, including plans for lithium-metal (Li-metal) technology to boost performance and energy density. The automaker announced that it has signed an agreement to work with SolidEnergy Systems (SES), an MIT spinoff developing prototype Li-metal batteries with nearly double the capacity of current lithium-ion cells.”

TECHNOLOGY
Xi’s Gambit: China Plans for a World Without American Technology
Paul Mozur and Steven Lee Myers | The New York Times
“China is freeing up tens of billions of dollars for its tech industry to borrow. It is cataloging the sectors where the United States or others could cut off access to crucial technologies. And when its leaders released their most important economic plans last week, they laid out their ambitions to become an innovation superpower beholden to none.”

SCIENCE
Imaginary Numbers May Be Essential for Describing Reality
Charlie Wood | Wired
“…physicists may have just shown for the first time that imaginary numbers are, in a sense, real. A group of quantum theorists designed an experiment whose outcome depends on whether nature has an imaginary side. Provided that quantum mechanics is correct—an assumption few would quibble with—the team’s argument essentially guarantees that complex numbers are an unavoidable part of our description of the physical universe.”

PHILOSOPHY
What Is Life? Its Vast Diversity Defies Easy Definition
Carl Zimmer | Quanta
“i‘It is commonly said,’ the scientists Frances Westall and André Brack wrote in 2018, ‘that there are as many definitions of life as there are people trying to define it.’ …As an observer of science and of scientists, I find this behavior strange. It is as if astronomers kept coming up with new ways to define stars. …With scientists adrift in an ocean of definitions, philosophers rowed out to offer lifelines.”

Image Credit: Kir Simakov / Unsplash Continue reading

Posted in Human Robots