Tag Archives: european

#438001 How an Israeli Startup Is Using AI to ...

Posted on January 27, 2021 by Android

The first baby conceived using in-vitro fertilization (IVF) was born in the UK in 1978. Over 40 years later, the technique has become commonplace, but its success rate is still fairly low at around 22 to 30 percent. A female-founded Israeli startup called Embryonics is setting out to change this by using artificial intelligence to screen embryos.

IVF consists of fertilizing a woman’s egg with her partner’s or a donor’s sperm outside of her body, creating an embryo that’s then implanted in the uterus. It’s not an easy process in any sense of the word—physically, emotionally, or financially. Insurance rarely covers IVF, and the costs run anywhere from $12,000 to $25,000 per cycle (a cycle takes about a month and includes stimulating a woman’s ovaries to produce eggs, extracting the eggs, inseminating them outside the body, and implanting an embryo).

Women have to give themselves daily hormone shots to stimulate egg production, and these can cause uncomfortable side effects. After so much stress and expense, it’s disheartening to think that the odds of a successful pregnancy are, at best, one in three.

A crucial factor in whether or not an IVF cycle works—that is, whether the embryo implants in the uterus and begins to develop into a healthy fetus—is the quality of the embryo. Doctors examine embryos through a microscope to determine how many cells they contain and whether they appear healthy, and choose the one that looks most viable.

But the human eye can only see so much, even with the help of a microscope; despite embryologists’ efforts to select the “best” embryo, success rates are still relatively low. “Many decisions are based on gut feeling or personal experience,” said Embryonics founder and CEO Yael Gold-Zamir. “Even if you go to the same IVF center, two experts can give you different opinions on the same embryo.”

This is where Embryonics’ technology comes in. They used 8,789 time-lapse videos of developing embryos to train an algorithm that predicts the likelihood of successful embryo implantation. A little less than half of the embryos from the dataset were graded by embryologists, and implantation data was integrated when it was available (as a binary “successful” or “failed” metric).

The algorithm uses geometric deep learning, a technique that takes a traditional convolutional neural network—which filters input data to create maps of its features, and is most commonly used for image recognition—and applies it to more complex data like 3D objects and graphs. Within days after fertilization, the embryo is still at the blastocyst stage, essentially a microscopic clump of just 200-300 cells; the algorithm uses this deep learning technique to spot and identify patterns in embryo development that human embryologists either wouldn’t see at all, or would require massive collation of data to validate.

On top of the embryo videos, Embryonics’ team incorporated patient data and environmental data from the lab into its algorithm, with encouraging results: the company reports that using its algorithm resulted in a 12 percent increase in positive predictive value (identifying embryos that would lead to implantation and healthy pregnancy) and a 29 percent increase in negative predictive value (identifying embyros that would not result in successful pregnancy) when compared to an external panel of embryologists.

TechCrunch reported last week that in a pilot of 11 women who used Embryonics’ algorithm to select their embryos, 6 are enjoying successful pregnancies, while 5 are still awaiting results.

Embryonics wasn’t the first group to think of using AI to screen embryos; a similar algorithm developed in 2019 by researchers at Weill Cornell Medicine was able to classify the quality of a set of embryo images with 97 percent accuracy. But Embryonics will be one of the first to bring this sort of technology to market. The company is waiting to receive approval from European regulatory bodies to be able to sell the software to fertility clinics in Europe.

Its timing is ripe: as more and more women delay having kids due to lifestyle and career-related factors, demand for IVF is growing, and will likely accelerate in coming years.

The company ultimately hopes to bring its product to the US, as well as to expand its work to include using data to improve hormonal stimulation.

Image Credit: Gerd Altmann from Pixabay Continue reading →

Posted in Human Robots

#437872 AlphaFold Proves That AI Can Crack ...

Posted on December 7, 2020 by Android

Any successful implementation of artificial intelligence hinges on asking the right questions in the right way. That’s what the British AI company DeepMind (a subsidiary of Alphabet) accomplished when it used its neural network to tackle one of biology’s grand challenges, the protein-folding problem. Its neural net, known as AlphaFold, was able to predict the 3D structures of proteins based on their amino acid sequences with unprecedented accuracy.

AlphaFold’s predictions at the 14th Critical Assessment of protein Structure Prediction (CASP14) were accurate to within an atom’s width for most of the proteins. The competition consisted of blindly predicting the structure of proteins that have only recently been experimentally determined—with some still awaiting determination.

Called the building blocks of life, proteins consist of 20 different amino acids in various combinations and sequences. A protein's biological function is tied to its 3D structure. Therefore, knowledge of the final folded shape is essential to understanding how a specific protein works—such as how they interact with other biomolecules, how they may be controlled or modified, and so on. “Being able to predict structure from sequence is the first real step towards protein design,” says Janet M. Thornton, director emeritus of the European Bioinformatics Institute. It also has enormous benefits in understanding disease-causing pathogens. For instance, at the moment only about 18 of the 26 proteins in the SARS-CoV-2 virus are known.

Predicting a protein’s 3D structure is a computational nightmare. In 1969 Cyrus Levinthal estimated that there are 10300 possible conformational combinations for a single protein, which would take longer than the age of the known universe to evaluate by brute force calculation. AlphaFold can do it in a few days.

As scientific breakthroughs go, AlphaFold’s discovery is right up there with the likes of James Watson and Francis Crick’s DNA double-helix model, or, more recently, Jennifer Doudna and Emmanuelle Charpentier’s CRISPR-Cas9 genome editing technique.

How did a team that just a few years ago was teaching an AI to master a 3,000-year-old game end up training one to answer a question plaguing biologists for five decades? That, says Briana Brownell, data scientist and founder of the AI company PureStrategy, is the beauty of artificial intelligence: The same kind of algorithm can be used for very different things.

“Whenever you have a problem that you want to solve with AI,” she says, “you need to figure out how to get the right data into the model—and then the right sort of output that you can translate back into the real world.”

DeepMind’s success, she says, wasn’t so much a function of picking the right neural nets but rather “how they set up the problem in a sophisticated enough way that the neural network-based modeling [could] actually answer the question.”

AlphaFold showed promise in 2018, when DeepMind introduced a previous iteration of their AI at CASP13, achieving the highest accuracy among all participants. The team had trained its to model target shapes from scratch, without using previously solved proteins as templates.

For 2020 they deployed new deep learning architectures into the AI, using an attention-based model that was trained end-to-end. Attention in a deep learning network refers to a component that manages and quantifies the interdependence between the input and output elements, as well as between the input elements themselves.

The system was trained on public datasets of the approximately 170,000 known experimental protein structures in addition to databases with protein sequences of unknown structures.

“If you look at the difference between their entry two years ago and this one, the structure of the AI system was different,” says Brownell. “This time, they’ve figured out how to translate the real world into data … [and] created an output that could be translated back into the real world.”

Like any AI system, AlphaFold may need to contend with biases in the training data. For instance, Brownell says, AlphaFold is using available information about protein structure that has been measured in other ways. However, there are also many proteins with as yet unknown 3D structures. Therefore, she says, a bias could conceivably creep in toward those kinds of proteins that we have more structural data for.

Thornton says it’s difficult to predict how long it will take for AlphaFold’s breakthrough to translate into real-world applications.

“We only have experimental structures for about 10 per cent of the 20,000 proteins [in] the human body,” she says. “A powerful AI model could unveil the structures of the other 90 per cent.”

Apart from increasing our understanding of human biology and health, she adds, “it is the first real step toward… building proteins that fulfill a specific function. From protein therapeutics to biofuels or enzymes that eat plastic, the possibilities are endless.” Continue reading →

Posted in Human Robots

#437796 AI Seeks ET: Machine Learning Powers ...

Posted on November 30, 2020 by Android

Can artificial intelligence help the search for life elsewhere in the solar system? NASA thinks the answer may be “yes”—and not just on Mars either.

A pilot AI system is now being tested for use on the ExoMars mission that is currently slated to launch in the summer or fall of 2022. The machine-learning algorithms being developed will help science teams decide how to test Martian soil samples to return only the most meaningful data.

For ExoMars, the AI system will only be used back on earth to analyze data gather by the ExoMars rover. But if the system proves to be as useful to the rovers as now suspected, a NASA mission to Saturn’s moon Titan (now scheduled for 2026 launch) could automate the scientific sleuthing process in the field. This mission will rely on the Dragonfly octocopter drone to fly from surface location to surface location through Titan’s dense atmosphere and drill for signs of life there.

The hunt for microbial life in another world’s soil, either as fossilized remnants or as present-day samples, is very challenging, says Eric Lyness, software lead of the NASA Goddard Planetary Environments Lab in Greenbelt, Md. There is of course no precedent to draw upon, because no one has yet succeeded in astrobiology’s holy grail quest.

But that doesn’t mean AI can’t provide substantial assistance. Lyness explained that for the past few years he’d been puzzling over how to automate portions of an exploratory mission’s geochemical investigation, wherever in the solar system the scientific craft may be.

Last year he decided to try machine learning. “So we got some interns,” he said. “People right out of college or in college, who have been studying machine learning. … And they did some amazing stuff. It turned into much more than we expected.” Lyness and his collaborators presented their scientific analysis algorithm at a geochemistry conference last month.

Illustration: ESA

The ExoMars rover, named Rosalind Franklin, will be the first that can drill down to 2-meter depths, where living soil bacteria could possibly be found.

ExoMars’s rover—named Rosalind Franklin, after one of the co-discoverers of DNA—will be the first that can drill down to 2-meter depths, beyond where solar UV light might penetrate and kill any life forms. In other words, ExoMars will be the first Martian craft with the ability to reach soil depths where living soil bacteria could possibly be found.

“We could potentially find forms of life, microbes or other things like that,” Lyness said. However, he quickly added, very little conclusive evidence today exists to suggest that there’s present-day (microbial) life on Mars. (NASA’s Curiosity rover has sent back some inexplicable observations of both methane and molecular oxygen in the Martian atmosphere that could conceivably be a sign of microbial life forms, though non-biological processes could explain these anomalies too.)

Less controversially, the Rosalind Franklin rover’s drill could also turn up fossilized evidence of life in the Martian soil from earlier epochs when Mars was more hospitable.

NASA’s contribution to the joint Russian/European Space Agency ExoMars project is an instrument called a mass spectrometer that will be used to analyze soil samples from the drill cores. Here, Lyness said, is where AI could really provide a helping hand.

Because the Dragonfly drone and possibly a future mission to Jupiter’s moon Europa would be operating in hostile environments with less opportunity for data transmission to Earth, automating a craft’s astrobiological exploration would be practically a requirement

The spectrometer, which studies the mass distribution of ions in a sample of material, works by blasting the drilled soil sample with a laser and then mapping out the atomic masses of the various molecules and portions of molecules that the laser has liberated. The problem is any given mass spectrum could originate from any number of source compounds, minerals and components. Which always makes analyzing a mass spectrum a gigantic puzzle.

Lyness said his group is studying the mineral montmorillonite, a commonplace component of the Martian soil, to see the many ways it might reveal itself in a mass spectrum. Then his team sneaks in an organic compound with the montmorillonite sample to see how that changes the mass spectrometer output.

“It could take a long time to really break down a spectrum and understand why you’re seeing peaks at certain [masses] in the spectrum,” he said. “So anything you can do to point scientists into a direction that says, ‘Don’t worry, I know it’s not this kind of thing or that kind of thing,’ they can more quickly identify what’s in there.”

Lyness said the ExoMars mission will provide a fertile training ground for his team’s as-yet-unnamed AI algorithm. (He said he’s open to suggestions—though, please, no spoof Boaty McBoatface submissions need apply.)

Because the Dragonfly drone and possibly a future astrobiology mission to Jupiter’s moon Europa would be operating in much more hostile environments with much less opportunity for data transmission back and forth to Earth, automating a craft’s astrobiological exploration would be practically a requirement.

All of which points to a future in mid-2030s in which a nuclear-powered octocopter on a moon of Saturn flies from location to location to drill for evidence of life on this tantalizingly bio-possible world. And machine learning will help power the science.

“We should be researching how to make the science instruments smarter,” Lyness said. “If you can make it smarter at the source, especially for planetary exploration, it has huge payoffs.” Continue reading →

Posted in Human Robots

#437745 Video Friday: Japan’s Giant Gundam ...

Posted on November 27, 2020 by Android

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):

AWS Cloud Robotics Summit – August 18-19, 2020 – [Online Conference]
CLAWAR 2020 – August 24-26, 2020 – [Virtual Conference]
ICUAS 2020 – September 1-4, 2020 – Athens, Greece
ICRES 2020 – September 28-29, 2020 – Taipei, Taiwan
AUVSI EXPONENTIAL 2020 – October 5-8, 2020 – [Online Conference]
IROS 2020 – October 25-29, 2020 – Las Vegas, Nev., USA
ICSR 2020 – November 14-16, 2020 – Golden, Co., USA
Let us know if you have suggestions for next week, and enjoy today’s videos.

It’s coming together—literally! Japan’s giant Gundam appears nearly finished and ready for its first steps. In a recent video, Gundam Factory Yokohama, which is constructing the 18-meter-tall, 25-ton walking robot, provided an update on the project. The video shows the Gundam getting its head attached—after being blessed by Shinto priests.

In the video update, they say the project is “steadily progressing” and further details will be announced around the end of September.

[ Gundam Factory Yokohama ]

Creating robots with emotional personalities will transform the usability of robots in the real-world. As previous emotive social robots are mostly based on statically stable robots whose mobility is limited, this work develops an animation to real-world pipeline that enables dynamic bipedal robots that can twist, wiggle, and walk to behave with emotions.

So that’s where Cassie’s eyes go.

[ Berkeley ]

Now that the DARPA SubT Cave Circuit is all virtual, here’s a good reminder of how it’ll work.

[ SubT ]

Since July 20, anyone 11+ years of age must wear a mask in closed public places in France. This measure also is highly recommended in many European, African and Persian Gulf countries. To support businesses and public places, SoftBank Robotics Europe unveils a new feature with Pepper: AI Face Mask Detection.

[ Softbank ]

University of Michigan researchers are developing new origami inspired methods for designing, fabricating and actuating micro-robots using heat.These improvements will expand the mechanical capabilities of the tiny bots, allowing them to fold into more complex shapes.

[ University of Michigan ]

Suzumori Endo Lab, Tokyo Tech has created various types of IPMC robots. Those robots are fabricated by novel 3D fabrication methods.

[ Suzimori Endo Lab ]

The most explode-y of drones manages not to explode this time.

[ SpaceX ]

At Amazon, we’re constantly innovating to support our employees, customers, and communities as effectively as possible. As our fulfillment and delivery teams have been hard at work supplying customers with items during the pandemic, Amazon’s robotics team has been working behind the scenes to re-engineer bots and processes to increase safety in our fulfillment centers.

While some folks are able to do their jobs at home with just a laptop and internet connection, it’s not that simple for other employees at Amazon, including those who spend their days building and testing robots. Some engineers have turned their homes into R&D labs to continue building these new technologies to better serve our customers and employees. Their creativity and resourcefulness to keep our important programs going is inspiring.

[ Amazon ]

Australian Army soldiers from 2nd/14th Light Horse Regiment (Queensland Mounted Infantry) demonstrated the PD-100 Black Hornet Nano unmanned aircraft vehicle during a training exercise at Shoalwater Bay Training Area, Queensland, on 4 May 2018.

This robot has been around for a long time—maybe 10 years or more? It makes you wonder what the next generation will look like, and if they can manage to make it even smaller.

[ FLIR ]

Event-based cameras are bio-inspired vision sensors whose pixels work independently from each other and respond asynchronously to brightness changes, with microsecond resolution. Their advantages make it possible to tackle challenging scenarios in robotics, such as high-speed and high dynamic range scenes. We present a solution to the problem of visual odometry from the data acquired by a stereo event-based camera rig.

[ Paper ] via [ HKUST ]

Emys can help keep kindergarteners sitting still for a long time, which is not small feat!

[ Emys ]

Introducing the RoboMaster EP Core, an advanced educational robot that was built to take learning to the next level and provides an all-in-one solution for STEAM-based classrooms everywhere, offering AI and programming projects for students of all ages and experience levels.

[ DJI ]

This Dutch food company Heemskerk uses ABB robots to automate their order picking. Their new solution reduces the amount of time the fresh produce spends in the supply chain, extending its shelf life, minimizing wastage, and creating a more sustainable solution for the fresh food industry.

[ ABB ]

This week’s episode of Pass the Torque features NASA’s Satellite Servicing Projects Division (NExIS) Robotics Engineer, Zakiya Tomlinson.

[ NASA ]

Massachusetts has been challenging Silicon Valley as the robotics capital of the United States. They’re not winning, yet. But they’re catching up.

[ MassTech ]

San Francisco-based Formant is letting anyone remotely take its Spot robot for a walk. Watch The Robot Report editors, based in Boston, take Spot for a walk around Golden Gate Park.

You can apply for this experience through Formant at the link below.

[ Formant ] via [ TRR ]

Thanks Steve!

An Institute for Advanced Study Seminar on “Theoretical Machine Learning,” featuring Peter Stone from UT Austin.

For autonomous robots to operate in the open, dynamically changing world, they will need to be able to learn a robust set of skills from relatively little experience. This talk begins by introducing Grounded Simulation Learning as a way to bridge the so-called reality gap between simulators and the real world in order to enable transfer learning from simulation to a real robot. It then introduces two new algorithms for imitation learning from observation that enable a robot to mimic demonstrated skills from state-only trajectories, without any knowledge of the actions selected by the demonstrator. Connections to theoretical advances in off-policy reinforcement learning will be highlighted throughout.

[ IAS ] Continue reading →

Posted in Human Robots

#437733 Video Friday: MIT Media Lab Developing ...

Posted on November 26, 2020 by Android

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here’s what we have so far (send us your events!):

AWS Cloud Robotics Summit – August 18-19, 2020 – [Online Conference]
CLAWAR 2020 – August 24-26, 2020 – [Online Conference]
ICUAS 2020 – September 1-4, 2020 – Athens, Greece
ICRES 2020 – September 28-29, 2020 – Taipei, Taiwan
AUVSI EXPONENTIAL 2020 – October 5-8, 2020 – [Online Conference]
IROS 2020 – October 25-29, 2020 – Las Vegas, Nev., USA
ICSR 2020 – November 14-16, 2020 – Golden, Colo., USA
Let us know if you have suggestions for next week, and enjoy today’s videos.

Very impressive local obstacle avoidance at a fairly high speed on a small drone, both indoors and outdoors.

[ FAST Lab ]

Matt Carney writes:

My PhD at MIT Media Lab has been the design and build of a next generation powered prosthesis. The bionic ankle, named TF8, was designed to provide biologically equivalent power and range of motion for plantarflexion-dorsiflexion. This video shows the process of going from a blank sheet of paper to people walking on it. Shown are three different people wearing the robot. About a dozen people have since been able to test the hardware.

[ MIT ]

Thanks Matt!

Exciting changes are coming to the iRobot® Home App. Get ready for new personalized experiences, improved features, and an easy-to-use interface. The update is rolling out over the next few weeks!

[ iRobot ]

MOFLIN is an AI Pet created from a totally new concept. It possesses emotional capabilities that evolve like living animals. With its warm soft fur, cute sounds, and adorable movement, you’d want to love it forever. We took a nature inspired approach and developed a unique algorithm that allows MOFLIN to learn and grow by constantly using its interactions to determine patterns and evaluate its surroundings from its sensors. MOFLIN will choose from an infinite number of mobile and sound pattern combinations to respond and express its feelings. To put it in simple terms, it’s like you’re interacting with a living pet.

You lost me at “it’s like you’re interacting with a living pet.”

[ Kickstarter ] via [ Gizmodo ]

This video is only robotics-adjacent, but it has applications for robotic insects. With a high-speed tracking system, we can now follow insects as they jump and fly, and watch how clumsy (but effective) they are at it.

[ Paper ]

Thanks Sawyer!

Suzumori Endo Lab, Tokyo Tech has developed self-excited pneumatic actuators that can be integrally molded by a 3D printer. These actuators use the “automatic flow path switching mechanism” we have devised.

[ Suzimori Endo Lab ]

Quadrupeds are getting so much better at deciding where to step rather than just stepping where they like and trying not to fall over.

[ RSL ]

Omnidirectional micro aerial vehicles are a growing field of research, with demonstrated advantages for aerial interaction and uninhibited observation. While systems with complete pose omnidirectionality and high hover efficiency have been developed independently, a robust system that combines the two has not been demonstrated to date. This paper presents the design and optimal control of a novel omnidirectional vehicle that can exert a wrench in any orientation while maintaining efficient flight configurations.

[ ASL ]

The latest in smooth humanoid walking from Dr. Guero.

[ YouTube ]

Will robots replace humans one day? When it comes to space exploration, robots are our precursors, gathering data to prepare humans for deep space. ESA robotics engineer Martin Azkarate discusses some of the upcoming missions involving robots and the unique science they will perform in this episode of Meet the Experts.

[ ESA ]

The Multi-robot Systems Group at FEE-CTU in Prague is working on an autonomous drone that detects fires and the shoots an extinguisher capsule at them.

[ MRS ]

This experiment with HEAP (Hydraulic Excavator for Autonomous Purposes) demonstrates our latest research in on-site and mobile digital fabrication with found materials. The embankment prototype in natural granular material was achieved using state of the art design and construction processes in mapping, modelling, planning and control. The entire process of building the embankment was fully autonomous. An operator was only present in the cabin for safety purposes.

[ RSL ]

The Simulation, Systems Optimization and Robotics Group (SIM) of Technische Universität Darmstadt’s Department of Computer Science conducts research on cooperating autonomous mobile robots, biologically inspired robots and numerical optimization and control methods.

[ SIM ]

Starting January 1, 2021, your drone platform of choice may be severely limited by the European Union’s new drone regulations. In this short video, senseFly’s Brock Ryder explains what that means for drone programs and operators and where senseFly drones fit in the EU’s new regulatory framework.

[ SenseFly ]

Nearly every company across every industry is looking for new ways to minimize human contact, cut costs and address the labor crunch in repetitive and dangerous jobs. WSJ explores why many are looking to robots as the solution for all three.

[ WSJ ]

You’ll need to prepare yourself emotionally for this video on “Examining Users’ Attitude Towards Robot Punishment.”

[ ACM ]

In this episode of the AI Podcast, Lex interviews Russ Tedrake (MIT and TRI) about biped locomotion, the DRC, home robots, and more.

[ AI Podcast ] Continue reading →

Posted in Human Robots