Tag Archives: 2019

#439077 How Scientists Grew Human Muscles in Pig ...

The little pigs bouncing around the lab looked exceedingly normal. Yet their adorable exterior hid a remarkable secret: each piglet carried two different sets of genes. For now, both sets came from their own species. But one day, one of those sets may be human.

The piglets are chimeras—creatures with intermingled sets of genes, as if multiple entities were seamlessly mashed together. Named after the Greek lion-goat-serpent monsters, chimeras may hold the key to an endless supply of human organs and tissues for transplant. The crux is growing these human parts in another animal—one close enough in size and function to our own.

Last week, a team from the University of Minnesota unveiled two mind-bending chimeras. One was joyous little piglets, each propelled by muscles grown from a different pig. Another was pig embryos, transplanted into surrogate pigs, that developed human muscles for more than 20 days.

The study, led by Drs. Mary and Daniel Garry at the University of Minnesota, had a therapeutic point: engineering a brilliant way to replace muscle loss, especially for the muscles around our skeletons that allow us to move and navigate the world. Trauma and injury, such as from firearm wounds or car crashes, can damage muscle tissue beyond the point of repair. Unfortunately, muscles are also stubborn in that donor tissue from cadavers doesn’t usually “take” at the injury site. For now, there are no effective treatments for severe muscle death, called volumetric muscle loss.

The new human-pig hybrids are designed to tackle this problem. Muscle wasting aside, the study also points to a clever “hack” that increases the amount of human tissue inside a growing pig embryo.

If further improved, the technology could “provide an unlimited supply of organs for transplantation,” said Dr. Mary Garry to Inverse. What’s more, because the human tissue can be sourced from patients themselves, the risk of rejection by the immune system is relatively low—even when grown inside a pig.

“The shortage of organs for heart transplantation, vascular grafting, and skeletal muscle is staggering,” said Garry. Human-animal chimeras could have a “seismic impact” that transforms organ transplantation and helps solve the organ shortage crisis.

That is, if society accepts the idea of a semi-humanoid pig.

Wait…But How?
The new study took a page from previous chimera recipes.

The main ingredients and steps go like this: first, you need an embryo that lacks the ability to develop a tissue or organ. This leaves an “empty slot” of sorts that you can fill with another set of genes—pig, human, or even monkey.

Second, you need to fine-tune the recipe so that the embryos “take” the new genes, incorporating them into their bodies as if they were their own. Third, the new genes activate to instruct the growing embryo to make the necessary tissue or organs without harming the overall animal. Finally, the foreign genes need to stay put, without cells migrating to another body part—say, the brain.

Not exactly straightforward, eh? The piglets are technological wonders that mix cutting-edge gene editing with cloning technologies.

The team went for two chimeras: one with two sets of pig genes, the other with a pig and human mix. Both started with a pig embryo that can’t make its own skeletal muscles (those are the muscles surrounding your bones). Using CRISPR, the gene-editing Swiss Army Knife, they snipped out three genes that are absolutely necessary for those muscles to develop. Like hitting a bullseye with three arrows simultaneously, it’s already a technological feat.

Here’s the really clever part: the muscles around your bones have a slightly different genetic makeup than the ones that line your blood vessels or the ones that pump your heart. While the resulting pig embryos had severe muscle deformities as they developed, their hearts beat as normal. This means the gene editing cut only impacted skeletal muscles.

Then came step two: replacing the missing genes. Using a microneedle, the team injected a fertilized and slightly developed pig egg—called a blastomere—into the embryo. If left on its natural course, a blastomere eventually develops into another embryo. This step “smashes” the two sets of genes together, with the newcomer filling the muscle void. The hybrid embryo was then placed into a surrogate, and roughly four months later, chimeric piglets were born.

Equipped with foreign DNA, the little guys nevertheless seemed totally normal, nosing around the lab and running everywhere without obvious clumsy stumbles. Under the microscope, their “xenomorph” muscles were indistinguishable from run-of-the-mill average muscle tissue—no signs of damage or inflammation, and as stretchy and tough as muscles usually are. What’s more, the foreign DNA seemed to have only developed into muscles, even though they were prevalent across the body. Extensive fishing experiments found no trace of the injected set of genes inside blood vessels or the brain.

A Better Human-Pig Hybrid
Confident in their recipe, the team next repeated the experiment with human cells, with a twist. Instead of using controversial human embryonic stem cells, which are obtained from aborted fetuses, they relied on induced pluripotent stem cells (iPSCs). These are skin cells that have been reverted back into a stem cell state.

Unlike previous attempts at making human chimeras, the team then scoured the genetic landscape of how pig and human embryos develop to find any genetic “brakes” that could derail the process. One gene, TP53, stood out, which was then promptly eliminated with CRISPR.

This approach provides a way for future studies to similarly increase the efficiency of interspecies chimeras, the team said.

The human-pig embryos were then carefully grown inside surrogate pigs for less than a month, and extensively analyzed. By day 20, the hybrids had already grown detectable human skeletal muscle. Similar to the pig-pig chimeras, the team didn’t detect any signs that the human genes had sprouted cells that would eventually become neurons or other non-muscle cells.

For now, human-animal chimeras are not allowed to grow to term, in part to stem the theoretical possibility of engineering humanoid hybrid animals (shudder). However, a sentient human-pig chimera is something that the team specifically addressed. Through multiple experiments, they found no trace of human genes in the embryos’ brain stem cells 20 and 27 days into development. Similarly, human donor genes were absent in cells that would become the hybrid embryos’ reproductive cells.

Despite bioethical quandaries and legal restrictions, human-animal chimeras have taken off, both as a source of insight into human brain development and a well of personalized organs and tissues for transplant. In 2019, Japan lifted its ban on developing human brain cells inside animal embryos, as well as the term limit—to global controversy. There’s also the question of animal welfare, given that hybrid clones will essentially become involuntary organ donors.

As the debates rage on, scientists are nevertheless pushing the limits of human-animal chimeras, while treading as carefully as possible.

“Our data…support the feasibility of the generation of these interspecies chimeras, which will serve as a model for translational research or, one day, as a source for xenotransplantation,” the team said.

Image Credit: Christopher Carson on Unsplash Continue reading

Posted in Human Robots

#439004 Video Friday: A Walking, Wheeling ...

Video Friday is your weekly selection of awesome robotics videos, collected by your Automaton bloggers. We’ll also be posting a weekly calendar of upcoming robotics events for the next few months; here's what we have so far (send us your events!):

RoboSoft 2021 – April 12-16, 2021 – [Online Conference]
ICRA 2021 – May 30-5, 2021 – Xi'an, China
Let us know if you have suggestions for next week, and enjoy today's videos.

This is a pretty terrible video, I think because it was harvested from WeChat, which is where Tencent decided to premiere its new quadruped robot.

Not bad, right? Its name is Max, it has a top speed of 25 kph thanks to its elbow wheels, and we know almost nothing else about it.

[ Tencent ]

Thanks Fan!

Can't bring yourself to mask-shame others? Build a robot to do it for you instead!

[ GitHub ]

Researchers at Georgia Tech have recently developed an entirely soft, long-stroke electromagnetic actuator using liquid metal, compliant magnetic composites, and silicone polymers. The robot was inspired by the motion of the Xenia coral, which pulses its polyps to circulate oxygen under water to promote photosynthesis.

In this work, power applied to soft coils generates an electromagnetic field, which causes the internal compliant magnet to move upward. This forces the squishy silicone linkages to convert linear to the rotational motion with an arclength of up to 42 mm with a bandwidth up to 30 Hz. This highly deformable, fast, and long-stroke actuator topology can be utilized for a variety of applications from biomimicry to fully-soft grasping to wearables applications.

[ Paper ] via [ Georgia Tech ]

Thanks Noah!

Jueying Mini Lite may look a little like a Boston Dynamics Spot, but according to DeepRobotics, its coloring is based on Bruce Lee's Kung Fu clothes.

[ DeepRobotics ]

Henrique writes, “I would like to share with you the supplementary video of our recent work accepted to ICRA 2021. The video features a quadruped and a full-size humanoid performing dynamic jumps, after a brief animated intro of what direct transcription is. Me and my colleagues have put a lot of hard work into this, and I am very proud of the results.”

Making big robots jump is definitely something to be proud of!

[ SLMC Edinburgh ]

Thanks Henrique!

The finals of the Powered Exoskeleton Race for Cybathlon Global 2020.

[ Cybathlon ]

Thanks Fan!

It's nice that every once in a while, the world can get excited about science and robots.

[ NASA ]

Playing the Imperial March over footage of an army of black quadrupeds may not be sending quite the right message.

[ Unitree ]

Kod*lab PhD students Abriana Stewart-Height, Diego Caporale and Wei-Hsi Chen, with former Kod*lab student Garrett Wenger were on set in the summer of 2019 to operate RHex for the filming of Lapsis, a first feature film by director and screenwriter Noah Hutton.

[ Kod*lab ]

In class 2.008, Design and Manufacturing II, mechanical engineering students at MIT learn the fundamental principles of manufacturing at scale by designing and producing their own yo-yos. Instructors stress the importance of sustainable practices in the global supply chain.

[ MIT ]

A short history of robotics, from ABB.

[ ABB ]

In this paper, we propose a whole-body planning framework that unifies dynamic locomotion and manipulation tasks by formulating a single multi-contact optimal control problem. This is demonstrated in a set of real hardware experiments done in free-motion, such as base or end-effector pose tracking, and while pushing/pulling a heavy resistive door. Robustness against model mismatches and external disturbances is also verified during these test cases.

[ Paper ]

This paper presents PANTHER, a real-time perception-aware (PA) trajectory planner in dynamic environments. PANTHER plans trajectories that avoid dynamic obstacles while also keeping them in the sensor field of view (FOV) and minimizing the blur to aid in object tracking.

Extensive hardware experiments in unknown dynamic environments with all the computation running onboard are presented, with velocities of up to 5.8 m/s, and with relative velocities (with respect to the obstacles) of up to 6.3 m/s. The only sensors used are an IMU, a forward-facing depth camera, and a downward-facing monocular camera.

[ MIT ]

With our SaaS solution, we enable robots to inspect industrial facilities. One of the robots our software supports, is the Boston Dynamics Spot robot. In this video we demonstrate how autonomous industrial inspection with the Boston Dynamics Spot Robot is performed with our teach and repeat solution.

[ Energy Robotics ]

In this week’s episode of Tech on Deck, learn about our first technology demonstration sent to Station: The Robotic Refueling Mission. This tech demo helped us develop the tools and techniques needed to robotically refuel a satellite in space, an important capability for space exploration.

[ NASA ]

At Covariant we are committed to research and development that will bring AI Robotics to the real world. As a part of this, we believe it's important to educate individuals on how these exciting innovations will make a positive, fundamental and global impact for years to come. In this presentation, our co-founder Pieter Abbeel breaks down his thoughts on the current state of play for AI robotics.

[ Covariant ]

How do you fly a helicopter on Mars? It takes Ingenuity and Perseverance. During this technology demo, Farah Alibay and Tim Canham will get into the details of how these craft will manage this incredible task.

[ NASA ]

Complex real-world environments continue to present significant challenges for fielding robotic teams, which often face expansive spatial scales, difficult and dynamic terrain, degraded environmental conditions, and severe communication constraints. Breakthrough technologies call for integrated solutions across autonomy, perception, networking, mobility, and human teaming thrusts. As such, the DARPA OFFSET program and the DARPA Subterranean Challenge seek novel approaches and new insights for discovering and demonstrating these innovative technologies, to help close critical gaps for robotic operations in complex urban and underground environments.

[ UPenn ] Continue reading

Posted in Human Robots

#438738 This Week’s Awesome Tech Stories From ...

ARTIFICIAL INTELLIGENCE
A New Artificial Intelligence Makes Mistakes—on Purpose
Will Knight | Wired
“It took about 50 years for computers to eviscerate humans in the venerable game of chess. A standard smartphone can now play the kind of moves that make a grandmaster’s head spin. But one artificial intelligence program is taking a few steps backward, to appreciate how average humans play—blunders and all.”

CRYPTOCURRENCY
Bitcoin’s Price Rises to $50,000 as Mainstream Institutions Hop On
Timothy B. Lee | Ars Technica
“Bitcoin’s price is now far above the previous peak of $19,500 reached in December 2017. Bitcoin’s value has risen by almost 70 percent since the start of 2021. No single factor seems to be driving the cryptocurrency’s rise. Instead, the price is rising as more and more mainstream organizations are deciding to treat it as an ordinary investment asset.”

SCIENCE
Million-Year-Old Mammoth Teeth Contain Oldest DNA Ever Found
Jeanne Timmons | Gizmodo
“An international team of scientists has sequenced DNA from mammoth teeth that is at least a million years old, if not older. This research, published today in Nature, not only provides exciting new insight into mammoth evolutionary history, it reveals an entirely unknown lineage of ancient mammoth.”

SCIENCE
Scientists Accidentally Discover Strange Creatures Under a Half Mile of Ice
Matt Simon | Wired
“i‘It’s like, bloody hell!’ Smith says. ‘It’s just one big boulder in the middle of a relatively flat seafloor. It’s not as if the seafloor is littered with these things.’ Just his luck to drill in the only wrong place. Wrong place for collecting seafloor muck, but the absolute right place for a one-in-a-million shot at finding life in an environment that scientists didn’t reckon could support much of it.”

BIOTECH
Highest-Resolution Images of DNA Reveal It’s Surprisingly Jiggly
George Dvorsky | Gizmodo
“Scientists have captured the highest-resolution images ever taken of DNA, revealing previously unseen twisting and squirming behaviors. …These hidden movements were revealed by computer simulations fed with the highest-resolution images ever taken of a single molecule of DNA. The new study is exposing previously unseen behaviors in the self-replicating molecule, and this research could eventually lead to the development of powerful new genetic therapies.”

TRANSPORTATION
The First Battery-Powered Tanker Is Coming to Tokyo
Maria Gallucci | IEEE Spectrum
“The Japanese tanker is Corvus’s first fully-electric coastal freighter project; the company hopes the e5 will be the first of hundreds more just like it. ‘We see it [as] a beachhead for the coastal shipping market globally,’ Puchalski said. ‘There are many other coastal freighter types that are similar in size and energy demand.’ The number of battery-powered ships has ballooned from virtually zero a decade ago to hundreds worldwide.”

SPACE
Report: NASA’s Only Realistic Path for Humans on Mars Is Nuclear Propulsion
Eric Berger | Ars Technica
“Conducted at the request of NASA, a broad-based committee of experts assessed the viability of two means of propulsion—nuclear thermal and nuclear electric—for a human mission launching to Mars in 2039. ‘One of the primary takeaways of the report is that if we want to send humans to Mars, and we want to do so repeatedly and in a sustainable way, nuclear space propulsion is on the path,’ said [JPL’s] Bobby Braun.”

NASA’s Perseverance Rover Successfully Lands on Mars
Joey Roulette | The Verge
“Perseverance hit Mars’ atmosphere on time at 3:48PM ET at speeds of about 12,100 miles per hour, diving toward the surface in an infamously challenging sequence engineers call the “seven minutes of terror.” With an 11-minute comms delay between Mars and Earth, the spacecraft had to carry out its seven-minute plunge at all by itself with a wickedly complex set of pre-programmed instructions.”

ENVIRONMENT
A First-of-Its-Kind Geoengineering Experiment Is About to Take Its First Step
James Temple | MIT Technology Review
“When I visited Frank Keutsch in the fall of 2019, he walked me down to the lab, where the tube, wrapped in gray insulation, ran the length of a bench in the back corner. By filling it with the right combination of gases, at particular temperatures and pressures, Keutsch and his colleagues had simulated the conditions some 20 kilometers above Earth’s surface. In testing how various chemicals react in this rarefied air, the team hoped to conduct a crude test of a controversial scheme known as solar geoengineering.”

Image Credit: Garcia / Unsplash Continue reading

Posted in Human Robots

#438001 How an Israeli Startup Is Using AI to ...

The first baby conceived using in-vitro fertilization (IVF) was born in the UK in 1978. Over 40 years later, the technique has become commonplace, but its success rate is still fairly low at around 22 to 30 percent. A female-founded Israeli startup called Embryonics is setting out to change this by using artificial intelligence to screen embryos.

IVF consists of fertilizing a woman’s egg with her partner’s or a donor’s sperm outside of her body, creating an embryo that’s then implanted in the uterus. It’s not an easy process in any sense of the word—physically, emotionally, or financially. Insurance rarely covers IVF, and the costs run anywhere from $12,000 to $25,000 per cycle (a cycle takes about a month and includes stimulating a woman’s ovaries to produce eggs, extracting the eggs, inseminating them outside the body, and implanting an embryo).

Women have to give themselves daily hormone shots to stimulate egg production, and these can cause uncomfortable side effects. After so much stress and expense, it’s disheartening to think that the odds of a successful pregnancy are, at best, one in three.

A crucial factor in whether or not an IVF cycle works—that is, whether the embryo implants in the uterus and begins to develop into a healthy fetus—is the quality of the embryo. Doctors examine embryos through a microscope to determine how many cells they contain and whether they appear healthy, and choose the one that looks most viable.

But the human eye can only see so much, even with the help of a microscope; despite embryologists’ efforts to select the “best” embryo, success rates are still relatively low. “Many decisions are based on gut feeling or personal experience,” said Embryonics founder and CEO Yael Gold-Zamir. “Even if you go to the same IVF center, two experts can give you different opinions on the same embryo.”

This is where Embryonics’ technology comes in. They used 8,789 time-lapse videos of developing embryos to train an algorithm that predicts the likelihood of successful embryo implantation. A little less than half of the embryos from the dataset were graded by embryologists, and implantation data was integrated when it was available (as a binary “successful” or “failed” metric).

The algorithm uses geometric deep learning, a technique that takes a traditional convolutional neural network—which filters input data to create maps of its features, and is most commonly used for image recognition—and applies it to more complex data like 3D objects and graphs. Within days after fertilization, the embryo is still at the blastocyst stage, essentially a microscopic clump of just 200-300 cells; the algorithm uses this deep learning technique to spot and identify patterns in embryo development that human embryologists either wouldn’t see at all, or would require massive collation of data to validate.

On top of the embryo videos, Embryonics’ team incorporated patient data and environmental data from the lab into its algorithm, with encouraging results: the company reports that using its algorithm resulted in a 12 percent increase in positive predictive value (identifying embryos that would lead to implantation and healthy pregnancy) and a 29 percent increase in negative predictive value (identifying embyros that would not result in successful pregnancy) when compared to an external panel of embryologists.

TechCrunch reported last week that in a pilot of 11 women who used Embryonics’ algorithm to select their embryos, 6 are enjoying successful pregnancies, while 5 are still awaiting results.

Embryonics wasn’t the first group to think of using AI to screen embryos; a similar algorithm developed in 2019 by researchers at Weill Cornell Medicine was able to classify the quality of a set of embryo images with 97 percent accuracy. But Embryonics will be one of the first to bring this sort of technology to market. The company is waiting to receive approval from European regulatory bodies to be able to sell the software to fertility clinics in Europe.

Its timing is ripe: as more and more women delay having kids due to lifestyle and career-related factors, demand for IVF is growing, and will likely accelerate in coming years.

The company ultimately hopes to bring its product to the US, as well as to expand its work to include using data to improve hormonal stimulation.

Image Credit: Gerd Altmann from Pixabay Continue reading

Posted in Human Robots

#437884 Hyundai Buys Boston Dynamics for Nearly ...

This morning just after 3 a.m. ET, Boston Dynamics sent out a media release confirming that Hyundai Motor Group has acquired a controlling interest in the company that values Boston Dynamics at US $1.1 billion:

Under the agreement, Hyundai Motor Group will hold an approximately 80 percent stake in Boston Dynamics and SoftBank, through one of its affiliates, will retain an approximately 20 percent stake in Boston Dynamics after the closing of the transaction.

The release is very long, but does have some interesting bits—we’ll go through them, and talk about what this might mean for both Boston Dynamics and Hyundai.

We’ve asked Boston Dynamics for comment, but they’ve been unusually quiet for the last few days (I wonder why!). So at this point just keep in mind that the only things we know for sure are the ones in the release. If (when?) we hear anything from either Boston Dynamics or Hyundai, we’ll update this post.

The first thing to be clear on is that the acquisition is split between Hyundai Motor Group’s affiliates, including Hyundai Motor, Hyundai Mobis, and Hyundai Glovis. Hyundai Motor makes cars, Hyundai Mobis makes car parts and seems to be doing some autonomous stuff as well, and Hyundai Glovis does logistics. There are many other groups that share the Hyundai name, but they’re separate entities, at least on paper. For example, there’s a Hyundai Robotics, but that’s part of Hyundai Heavy Industries, a different company than Hyundai Motor Group. But for this article, when we say “Hyundai,” we’re talking about Hyundai Motor Group.

What’s in it for Hyundai?
Let’s get into the press release, which is filled with press release-y terms like “synergies” and “working together”—you can view the whole thing here—but still has some parts that convey useful info.

By establishing a leading presence in the field of robotics, the acquisition will mark another major step for Hyundai Motor Group toward its strategic transformation into a Smart Mobility Solution Provider. To propel this transformation, Hyundai Motor Group has invested substantially in development of future technologies, including in fields such as autonomous driving technology, connectivity, eco-friendly vehicles, smart factories, advanced materials, artificial intelligence (AI), and robots.

If Hyundai wants to be a “Smart Mobility Solution Provider” with a focus on vehicles, it really seems like there’s a whole bunch of other ways they could have spent most of a billion dollars that would get them there quicker. Will Boston Dynamics’ expertise help them develop autonomous driving technology? Sure, I guess, but why not just buy an autonomous car startup instead? Boston Dynamics is more about “robots,” which happens to be dead last on the list above.

There was some speculation a couple of weeks ago that Hyundai was going to try and leverage Boston Dynamics to make a real version of this hybrid wheeled/legged concept car, so if that’s what Hyundai means by “Smart Mobility Solution Provider,” then I suppose the Boston Dynamics acquisition makes more sense. Still, I think that’s unlikely, because it’s just a concept car, after all.

In addition to “smart mobility,” which seems like a longer-term goal for Hyundai, the company also mentions other, more immediate benefits from the acquisition:

Advanced robotics offer opportunities for rapid growth with the potential to positively impact society in multiple ways. Boston Dynamics is the established leader in developing agile, mobile robots that have been successfully integrated into various business operations. The deal is also expected to allow Hyundai Motor Group and Boston Dynamics to leverage each other’s respective strengths in manufacturing, logistics, construction and automation.

“Successfully integrated” might be a little optimistic here. They’re talking about Spot, of course, but I think the best you could say at this point is that Spot is in the middle of some promising pilot projects. Whether it’ll be successfully integrated in the sense that it’ll have long-term commercial usefulness and value remains to be seen. I’m optimistic about this as well, but Spot is definitely not there yet.

What does probably hold a lot of value for Hyundai is getting Spot, Pick, and perhaps even Handle into that “manufacturing, logistics, construction” stuff. This is the bread and butter for robots right now, and Boston Dynamics has plenty of valuable technology to offer in those spaces.

Photo: Bob O’Connor

Boston Dynamics is selling Spot for $74,500, shipping included.

Betting on Spot and Pick
With Boston Dynamics founder Marc Raibert’s transition to Chairman of the company, the CEO position is now occupied by Robert Playter, the long-time VP of engineering and more recently COO at Boston Dynamics. Here’s his statement from the release:

“Boston Dynamics’ commercial business has grown rapidly as we’ve brought to market the first robot that can automate repetitive and dangerous tasks in workplaces designed for human-level mobility. We and Hyundai share a view of the transformational power of mobility and look forward to working together to accelerate our plans to enable the world with cutting edge automation, and to continue to solve the world’s hardest robotics challenges for our customers.”

Whether Spot is in fact “the first robot that can automate repetitive and dangerous tasks in workplaces designed for human-level mobility” on the market is perhaps something that could be argued against, although I won’t. Whether or not it was the first robot that can do these kinds of things, it’s definitely not the only robot that do these kinds of things, and going forward, it’s going to be increasingly challenging for Spot to maintain its uniqueness.

For a long time, Boston Dynamics totally owned the quadruped space. Now, they’re one company among many—ANYbotics and Unitree are just two examples of other quadrupeds that are being successfully commercialized. Spot is certainly very capable and easy to use, and we shouldn’t underestimate the effort required to create a robot as complex as Spot that can be commercially used and supported. But it’s not clear how long they’ll maintain that advantage, with much more affordable platforms coming out of Asia, and other companies offering some unique new capabilities.

Photo: Boston Dynamics

Boston Dynamics’ Handle is an all-electric robot featuring a leg-wheel hybrid mobility system, a manipulator arm with a vacuum gripper, and a counterbalancing tail.

Boston Dynamics’ picking system, which stemmed from their 2019 acquisition of Kinema Systems, faces the same kinds of challenges—it’s very good, but it’s not totally unique.

Boston Dynamics produces highly capable mobile robots with advanced mobility, dexterity and intelligence, enabling automation in difficult, dangerous, or unstructured environments. The company launched sales of its first commercial robot, Spot in June of 2020 and has since sold hundreds of robots in a variety of industries, such as power utilities, construction, manufacturing, oil and gas, and mining. Boston Dynamics plans to expand the Spot product line early next year with an enterprise version of the robot with greater levels of autonomy and remote inspection capabilities, and the release of a robotic arm, which will be a breakthrough in mobile manipulation.

Boston Dynamics is also entering the logistics automation market with the industry leading Pick, a computer vision-based depalletizing solution, and will introduce a mobile robot for warehouses in 2021.

Huh. We’ll be trying to figure out what “greater levels of autonomy” means, as well as whether the “mobile robot for warehouses” is Handle, or something more like an autonomous mobile robot (AMR) platform. I’d honestly be surprised if Handle was ready for work outside of Boston Dynamics next year, and it’s hard to imagine how Boston Dynamics could leverage their expertise into the AMR space with something that wouldn’t just seem… Dull, compared to what they usually do. I hope to be surprised, though!

A new deep-pocketed benefactor

Hyundai Motor Group’s decision to acquire Boston Dynamics is based on its growth potential and wide range of capabilities.

“Wide range of capabilities” we get, but that other phrase, “growth potential,” has a heck of a lot wrapped up in it. At the moment, Boston Dynamics is nowhere near profitable, as far as we know. SoftBank acquired Boston Dynamics in 2017 for between one hundred and two hundred million, and over the last three years they’ve poured hundreds of millions more into Boston Dynamics.

Hyundai’s 80 percent stake just means that they’ll need to take over the majority of that support, and perhaps even increase it if Boston Dynamics’ growth is one of their primary goals. Hyundai can’t have a reasonable expectation that Boston Dynamics will be profitable any time soon; they’re selling Spots now, but it’s an open question whether Spot will manage to find a scalable niche in which it’ll be useful in the sort of volume that will make it a sustainable commercial success. And even if it does become a success, it seems unlikely that Spot by itself will make a significant dent in Boston Dynamics’ burn rate anytime soon. Boston Dynamics will have more products of course, but it’s going to take a while, and Hyundai will need to support them in the interim.

Depending on whether Hyundai views Boston Dynamics as a company that does research or a company that makes robots that are useful and profitable, it may be difficult for Boston Dynamics to justify the cost to develop the
next Atlas, when the
current one still seems so far from commercialization

It’s become clear that to sustain itself, Boston Dynamics needs a benefactor with very deep pockets and a long time horizon. Initially, Boston Dynamics’ business model (or whatever you want to call it) was to do bespoke projects for defense-ish folks like DARPA, but from what we understand Boston Dynamics stopped that sort of work after Google acquired them back in 2013. From one perspective, that government funding did exactly what it was supposed to do, which was to fund the development of legged robots through low TRLs (technology readiness levels) to the point where they could start to explore commercialization.

The question now, though, is whether Hyundai is willing to let Boston Dynamics undertake the kinds of low-TRL, high-risk projects that led from BigDog to LS3 to Spot, and from PETMAN to DRC Atlas to the current Atlas. So will Hyundai be cool about the whole thing and be the sort of benefactor that’s willing to give Boston Dynamics the resources that they need to keep doing what they’re doing, without having to answer too many awkward questions about things like practicality and profitability? Hyundai can certainly afford to do this, but so could SoftBank, and Google—the question is whether Hyundai will want to, over the length of time that’s required for the development of the kind of ultra-sophisticated robotics hardware that Boston Dynamics specializes in.

To put it another way: Depending whether Hyundai’s perspective on Boston Dynamics is as a company that does research or a company that makes robots that are useful and profitable, it may be difficult for Boston Dynamics to justify the cost to develop the next Atlas, when the current one still seems so far from commercialization.

Google, SoftBank, now Hyundai

Boston Dynamics possesses multiple key technologies for high-performance robots equipped with perception, navigation, and intelligence.

Hyundai Motor Group’s AI and Human Robot Interaction (HRI) expertise is highly synergistic with Boston Dynamics’s 3D vision, manipulation, and bipedal/quadruped expertise.

As it turns out, Hyundai Motors does have its own robotics lab, called Hyundai Motors Robotics Lab. Their website is not all that great, but here’s a video from last year:

I’m not entirely clear on what Hyundai means when they use the word “synergistic” when they talk about their robotics lab and Boston Dynamics, but it’s a little bit concerning. Usually, when a big company buys a little company that specializes in something that the big company is interested in, the idea is that the little company, to some extent, will be absorbed into the big company to give them some expertise in that area. Historically, however, Boston Dynamics has been highly resistant to this, maintaining its post-acquisition independence and appearing to be very reluctant to do anything besides what it wants to do, at whatever pace it wants to do it, and as by itself as possible.

From what we understand, Boston Dynamics didn’t integrate particularly well with Google’s robotics push in 2013, and we haven’t seen much evidence that SoftBank’s experience was much different. The most direct benefit to SoftBank (or at least the most visible one) was the addition of a fleet of Spot robots to the SoftBank Hawks baseball team cheerleading squad, along with a single (that we know about) choreographed gymnastics routine from an Atlas robot that was only shown on video.

And honestly, if you were a big manufacturing company with a bunch of money and you wanted to build up your own robotics program quickly, you’d probably have much better luck picking up some smaller robotics companies who were a bit less individualistic and would probably be more amenable to integration and would cost way less than a billion dollars-ish. And if integration is ultimately Hyundai’s goal, we’ll be very sad, because it’ll likely signal the end of Boston Dynamics doing the unfettered crazy stuff that we’ve grown to love.

Photo: Bob O’Connor

Possibly the most agile humanoid robot ever built, Atlas can run, climb, jump over obstacles, and even get up after a fall.

Boston Dynamics contemplates its future

The release ends by saying that the transaction is “subject to regulatory approvals and other customary closing conditions” and “is expected to close by June of 2021.” Again, you can read the whole thing here.

My initial reaction is that, despite the “synergies” described by Hyundai, it’s certainly not immediately obvious why the company wants to own 80 percent of Boston Dynamics. I’d also like a better understanding of how they arrived at the $1.1 billion valuation. I’m not saying this because I don’t believe in what Boston Dynamics is doing or in the inherent value of the company, because I absolutely do, albeit perhaps in a slightly less tangible sense. But when you start tossing around numbers like these, a big pile of expectations inevitably comes along with them. I hope that Boston Dynamics is unique enough that the kinds of rules that normally apply to robotics companies (or companies in general) can be set aside, at least somewhat, but I also worry that what made Boston Dynamics great was the explicit funding for the kinds of radical ideas that eventually resulted in robots like Atlas and Spot.

Can Hyundai continue giving Boston Dynamics the support and freedom that they need to keep doing the kinds of things that have made them legendary? I certainly hope so. Continue reading

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